hydrogen sulfide has been researched along with Hyperhomocysteinemia in 47 studies
Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.
Hyperhomocysteinemia: Condition in which the plasma levels of homocysteine and related metabolites are elevated (
| Excerpt | Relevance | Reference |
|---|---|---|
| "The influence of hyperhomocysteinemia (HHCy) on cardiovascular disease (CVD) remains unclear." | 9.12 | Hyperhomocysteinemia and Cardiovascular Disease: Is the Adenosinergic System the Missing Link? ( Deharo, P; Fromonot, J; Guieu, R; Marlinge, M; Mottola, G; Paganelli, F; Ruf, J, 2021) |
| "Hyperhomocysteinemia, an increased level of plasma homocysteine, is an independent risk factor for the development of premature arterial fibrosis with peripheral and cerebro-vascular, neurogenic and hypertensive heart disease, coronary occlusion and myocardial infarction, as well as venous thromboembolism." | 8.86 | Homocysteine to hydrogen sulfide or hypertension. ( Mishra, PK; Sen, U; Tyagi, N; Tyagi, SC, 2010) |
| "Hydrogen sulfide donors can block the cardiovascular injury of hyperhomocysteinemia." | 7.91 | Hydrogen sulfide lowers hyperhomocysteinemia dependent on cystathionine γ lyase S-sulfhydration in ApoE-knockout atherosclerotic mice. ( Cai, J; Cui, C; Cui, Q; Fan, J; Geng, B; Jiang, S; Li, S; Tang, X; Xu, G; Yang, J; Zhang, J; Zheng, F, 2019) |
| "Elevated level of homocysteine (Hcy), known as hyperhomocysteinemia (HHcy), is associated with end-stage renal diseases." | 7.75 | Hydrogen sulfide ameliorates hyperhomocysteinemia-associated chronic renal failure. ( Abe, OA; Basu, P; Givvimani, S; Metreveli, N; Passmore, JC; Sen, U; Shah, KS; Tyagi, N; Tyagi, SC, 2009) |
| "Atherosclerosis is a chronic, complex, and progressive pathological process in large and medium sized arteries." | 6.46 | Endogenous hydrogen sulfide is involved in the pathogenesis of atherosclerosis. ( Chaoshu, T; Hongfang, J; Junbao, D; Qiao, W, 2010) |
| "Hydrogen sulfide (H2S) is a gaseous mediator that promotes tissue repair and resolution of inflammation." | 5.40 | Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis. ( Agbor, TA; Blackler, RW; Ferraz, JG; Flannigan, KL; Khan, WI; Kim, JJ; Verdu, EF; Wallace, JL, 2014) |
| "Hydrogen sulfide (H(2)S) has recently been identified as a regulator of various physiological events, including vasodilation, angiogenesis, antiapoptotic, and cellular signaling." | 5.38 | Increased endogenous H2S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia. ( Coley, DM; Givvimani, S; Kundu, S; Metreveli, N; Mishra, PK; Qipshidze, N; Sathnur, PB; Sen, U; Tyagi, N; Tyagi, SC, 2012) |
| "The influence of hyperhomocysteinemia (HHCy) on cardiovascular disease (CVD) remains unclear." | 5.12 | Hyperhomocysteinemia and Cardiovascular Disease: Is the Adenosinergic System the Missing Link? ( Deharo, P; Fromonot, J; Guieu, R; Marlinge, M; Mottola, G; Paganelli, F; Ruf, J, 2021) |
| "Hyperhomocysteinemia/Homocysteinuria is characterized by an increased level of toxic homocysteine in the plasma." | 5.01 | Disturbed homocysteine metabolism is associated with cancer. ( Arora, R; Bansal, AK; Bhattacharya, R; Hasan, T; Sharma, GS; Singh, LR, 2019) |
| "Hyperhomocysteinemia, an increased level of plasma homocysteine, is an independent risk factor for the development of premature arterial fibrosis with peripheral and cerebro-vascular, neurogenic and hypertensive heart disease, coronary occlusion and myocardial infarction, as well as venous thromboembolism." | 4.86 | Homocysteine to hydrogen sulfide or hypertension. ( Mishra, PK; Sen, U; Tyagi, N; Tyagi, SC, 2010) |
| "Hydrogen sulfide donors can block the cardiovascular injury of hyperhomocysteinemia." | 3.91 | Hydrogen sulfide lowers hyperhomocysteinemia dependent on cystathionine γ lyase S-sulfhydration in ApoE-knockout atherosclerotic mice. ( Cai, J; Cui, C; Cui, Q; Fan, J; Geng, B; Jiang, S; Li, S; Tang, X; Xu, G; Yang, J; Zhang, J; Zheng, F, 2019) |
| "An elevated level of homocysteine called hyperhomocysteinemia (HHcy) is associated with pathological cardiac remodeling." | 3.81 | Hydrogen sulfide mitigates homocysteine-mediated pathological remodeling by inducing miR-133a in cardiomyocytes. ( Kesherwani, V; Mishra, PK; Nandi, SS; Shahshahan, HR; Sharawat, SK, 2015) |
| "Hyperhomocysteinemia (HHcy) is an independent risk factor of atherosclerosis and other cardiovascular diseases." | 3.81 | Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter. ( Cao, YJ; Cheng, J; Du, HP; Hu, LF; Li, JJ; Li, Q; Liu, CF; Wang, F; Wang, YL; Xu, XS; You, SJ, 2015) |
| "Homocysteine (Hcy) can elicit neuronal cell death, and hyperhomocysteinemia is a strong independent risk factor for Alzheimer's disease." | 3.80 | Hydrogen sulfide inhibits homocysteine-induced endoplasmic reticulum stress and neuronal apoptosis in rat hippocampus via upregulation of the BDNF-TrkB pathway. ( Li, MH; Tang, JP; Tang, XQ; Wang, CY; Wang, L; Wei, HJ; Xu, JH; Zhang, P; Zou, W, 2014) |
| "In this study we tested the hypothesis that H(2)S regulates collagen deposition, matrix metalloproteinases (MMP) and inflammatory molecules during hyperhomocysteinemia (HHcy) resulting in attenuation of glomerulosclerosis and improved renal function." | 3.76 | Hydrogen sulfide regulates homocysteine-mediated glomerulosclerosis. ( Abe, O; Gargoum, R; Munjal, C; Qipshidze, N; Sen, U; Tyagi, SC, 2010) |
| "Elevated level of homocysteine (Hcy), known as hyperhomocysteinemia (HHcy), is associated with end-stage renal diseases." | 3.75 | Hydrogen sulfide ameliorates hyperhomocysteinemia-associated chronic renal failure. ( Abe, OA; Basu, P; Givvimani, S; Metreveli, N; Passmore, JC; Sen, U; Shah, KS; Tyagi, N; Tyagi, SC, 2009) |
| "Uremia is associated with a high cardiovascular mortality, the causes of which are still not completely explained, but are related to uremic toxicity, due to the accumulation of retention products." | 2.55 | The Sulfur Metabolite Lanthionine: Evidence for a Role as a Novel Uremic Toxin. ( Ingrosso, D; Perna, AF; Trepiccione, F; Zacchia, M, 2017) |
| "Atherosclerosis is a chronic, complex, and progressive pathological process in large and medium sized arteries." | 2.46 | Endogenous hydrogen sulfide is involved in the pathogenesis of atherosclerosis. ( Chaoshu, T; Hongfang, J; Junbao, D; Qiao, W, 2010) |
| "Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases." | 2.43 | [A new strategy to treat hyperhomocysteinemia]. ( Chang, L; Du, JB; Geng, B; Tang, CS, 2005) |
| " Chronic administration of CSE inhibitor induces arterial hypertension in the rat." | 2.42 | [Hydrogen sulfide as a biologically active mediator in the cardiovascular system]. ( Bełtowski, J, 2004) |
| "Hydrogen sulfide (H2S) has potent anti-inflammatory, anti-oxidative, and anti-apoptotic effects." | 1.42 | Hydrogen Sulfide Epigenetically Attenuates Homocysteine-Induced Mitochondrial Toxicity Mediated Through NMDA Receptor in Mouse Brain Endothelial (bEnd3) Cells. ( Kalani, A; Kamat, PK; Tyagi, N; Tyagi, SC, 2015) |
| "Hydrogen sulfide (H2S) is a gaseous mediator that promotes tissue repair and resolution of inflammation." | 1.40 | Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis. ( Agbor, TA; Blackler, RW; Ferraz, JG; Flannigan, KL; Khan, WI; Kim, JJ; Verdu, EF; Wallace, JL, 2014) |
| "Hydrogen sulfide (H(2)S) has recently been identified as a regulator of various physiological events, including vasodilation, angiogenesis, antiapoptotic, and cellular signaling." | 1.38 | Increased endogenous H2S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia. ( Coley, DM; Givvimani, S; Kundu, S; Metreveli, N; Mishra, PK; Qipshidze, N; Sathnur, PB; Sen, U; Tyagi, N; Tyagi, SC, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (14.89) | 29.6817 |
| 2010's | 31 (65.96) | 24.3611 |
| 2020's | 9 (19.15) | 2.80 |
| Authors | Studies |
|---|---|
| Nakladal, D | 1 |
| Lambooy, SPH | 1 |
| Mišúth, S | 1 |
| Čepcová, D | 1 |
| Joschko, CP | 1 |
| van Buiten, A | 1 |
| Goris, M | 1 |
| Hoogstra-Berends, F | 1 |
| Kloosterhuis, NJ | 1 |
| Huijkman, N | 1 |
| van de Sluis, B | 1 |
| Diercks, GF | 1 |
| Buikema, JH | 1 |
| Henning, RH | 1 |
| Deelman, LE | 1 |
| Yan, X | 1 |
| He, M | 1 |
| Huang, H | 1 |
| Wang, Q | 1 |
| Hu, Y | 1 |
| Wang, X | 1 |
| Jin, M | 1 |
| Wang, Y | 3 |
| Xia, Y | 1 |
| Li, Y | 1 |
| Chen, G | 1 |
| Cheng, J | 2 |
| Jia, J | 1 |
| Kumar, M | 3 |
| Sandhir, R | 3 |
| Nechiporuk, V | 1 |
| Mel'nyk, A | 1 |
| Korda, M | 1 |
| Pentiuk, N | 1 |
| Kachula, S | 1 |
| Yakovleva, O | 1 |
| Bogatova, K | 1 |
| Mukhtarova, R | 1 |
| Yakovlev, A | 1 |
| Shakhmatova, V | 1 |
| Gerasimova, E | 1 |
| Ziyatdinova, G | 1 |
| Hermann, A | 1 |
| Sitdikova, G | 1 |
| Blachier, F | 1 |
| Andriamihaja, M | 1 |
| Blais, A | 1 |
| Zhao, X | 1 |
| Zhang, L | 1 |
| Liu, X | 2 |
| Zhao, Z | 2 |
| Zhong, X | 2 |
| Paganelli, F | 1 |
| Mottola, G | 2 |
| Fromonot, J | 2 |
| Marlinge, M | 1 |
| Deharo, P | 2 |
| Guieu, R | 2 |
| Ruf, J | 2 |
| Jiang, S | 2 |
| Xu, W | 1 |
| Chen, Z | 1 |
| Cui, C | 2 |
| Fan, X | 1 |
| Cai, J | 2 |
| Gong, Y | 1 |
| Geng, B | 3 |
| Cui, X | 1 |
| Navneet, S | 1 |
| Wang, J | 1 |
| Roon, P | 1 |
| Chen, W | 1 |
| Xian, M | 1 |
| Smith, SB | 1 |
| Modi, M | 1 |
| Cianciolo, G | 1 |
| Cappuccilli, M | 1 |
| La Manna, G | 1 |
| Behera, J | 2 |
| George, AK | 1 |
| Voor, MJ | 2 |
| Tyagi, SC | 8 |
| Tyagi, N | 7 |
| Shi, S | 1 |
| Li, H | 1 |
| Gao, F | 1 |
| Kelly, KE | 1 |
| Metreveli, N | 3 |
| Yakovleva, OV | 1 |
| Ziganshina, AR | 1 |
| Dmitrieva, SA | 1 |
| Arslanova, AN | 1 |
| Yakovlev, AV | 1 |
| Minibayeva, FV | 1 |
| Khaertdinov, NN | 1 |
| Ziyatdinova, GK | 1 |
| Giniatullin, RA | 1 |
| Sitdikova, GF | 1 |
| Esse, R | 1 |
| Barroso, M | 1 |
| Tavares de Almeida, I | 1 |
| Castro, R | 1 |
| Hasan, T | 1 |
| Arora, R | 1 |
| Bansal, AK | 1 |
| Bhattacharya, R | 1 |
| Sharma, GS | 1 |
| Singh, LR | 1 |
| Fan, J | 1 |
| Zheng, F | 1 |
| Li, S | 1 |
| Zhang, J | 1 |
| Cui, Q | 1 |
| Yang, J | 1 |
| Tang, X | 2 |
| Xu, G | 1 |
| d'Emmanuele di Villa Bianca, R | 1 |
| Mitidieri, E | 1 |
| Di Minno, MN | 1 |
| Kirkby, NS | 1 |
| Warner, TD | 1 |
| Di Minno, G | 1 |
| Cirino, G | 1 |
| Sorrentino, R | 1 |
| Jurkowska, H | 1 |
| Kaczor-Kamińska, M | 1 |
| Bronowicka-Adamska, P | 1 |
| Wróbel, M | 1 |
| Wei, HJ | 1 |
| Xu, JH | 1 |
| Li, MH | 1 |
| Tang, JP | 1 |
| Zou, W | 1 |
| Zhang, P | 1 |
| Wang, L | 1 |
| Wang, CY | 1 |
| Tang, XQ | 1 |
| Altaany, Z | 1 |
| Moccia, F | 1 |
| Munaron, L | 1 |
| Mancardi, D | 1 |
| Wang, R | 1 |
| Kamat, PK | 1 |
| Kalani, A | 1 |
| Flannigan, KL | 1 |
| Agbor, TA | 1 |
| Blackler, RW | 1 |
| Kim, JJ | 1 |
| Khan, WI | 1 |
| Verdu, EF | 1 |
| Ferraz, JG | 1 |
| Wallace, JL | 1 |
| Nakano, S | 1 |
| Ishii, I | 1 |
| Shinmura, K | 1 |
| Tamaki, K | 1 |
| Hishiki, T | 1 |
| Akahoshi, N | 1 |
| Ida, T | 1 |
| Nakanishi, T | 1 |
| Kamata, S | 1 |
| Kumagai, Y | 1 |
| Akaike, T | 1 |
| Fukuda, K | 1 |
| Sano, M | 1 |
| Suematsu, M | 1 |
| Kesherwani, V | 1 |
| Nandi, SS | 1 |
| Sharawat, SK | 1 |
| Shahshahan, HR | 1 |
| Mishra, PK | 3 |
| Li, JJ | 1 |
| Li, Q | 1 |
| Du, HP | 1 |
| Wang, YL | 1 |
| You, SJ | 1 |
| Wang, F | 1 |
| Xu, XS | 1 |
| Cao, YJ | 1 |
| Liu, CF | 1 |
| Hu, LF | 1 |
| Bruzzese, L | 1 |
| Fenouillet, E | 1 |
| Durand-Gorde, JM | 1 |
| Condo, J | 1 |
| Kipson, N | 1 |
| Perna, AF | 3 |
| Di Nunzio, A | 1 |
| Amoresano, A | 1 |
| Pane, F | 1 |
| Fontanarosa, C | 1 |
| Pucci, P | 1 |
| Vigorito, C | 1 |
| Cirillo, G | 1 |
| Zacchia, M | 2 |
| Trepiccione, F | 2 |
| Ingrosso, D | 3 |
| Chiku, T | 1 |
| Padovani, D | 1 |
| Zhu, W | 1 |
| Singh, S | 1 |
| Vitvitsky, V | 1 |
| Banerjee, R | 1 |
| Sen, U | 4 |
| Basu, P | 1 |
| Abe, OA | 1 |
| Givvimani, S | 3 |
| Shah, KS | 1 |
| Passmore, JC | 1 |
| Wei, H | 1 |
| Zhang, R | 1 |
| Jin, H | 1 |
| Liu, D | 1 |
| Tang, C | 1 |
| Du, J | 1 |
| Qipshidze, N | 3 |
| Kundu, S | 2 |
| Kapoor, S | 1 |
| Vacek, JC | 1 |
| Qiao, W | 1 |
| Chaoshu, T | 1 |
| Hongfang, J | 1 |
| Junbao, D | 1 |
| Munjal, C | 1 |
| Abe, O | 1 |
| Gargoum, R | 1 |
| Luciano, MG | 1 |
| Raiola, I | 1 |
| Pulzella, P | 1 |
| Sepe, I | 1 |
| Lanza, D | 1 |
| Violetti, E | 1 |
| Capasso, R | 1 |
| Lombardi, C | 1 |
| De Santo, NG | 1 |
| Yuzawa, Y | 1 |
| Sathnur, PB | 1 |
| Coley, DM | 1 |
| Bełtowski, J | 1 |
| Carson, RJ | 1 |
| Chang, L | 1 |
| Du, JB | 1 |
| Tang, CS | 1 |
| Distrutti, E | 1 |
| Mencarelli, A | 1 |
| Santucci, L | 1 |
| Renga, B | 1 |
| Orlandi, S | 1 |
| Donini, A | 1 |
| Shah, V | 1 |
| Fiorucci, S | 1 |
| Tripodi, A | 1 |
| Chantarangkul, V | 1 |
| Tan, Y | 1 |
| Hoffman, RM | 1 |
| Cattaneo, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Homocysteine in Myocardial Infarction Patients in a Tertiary Care Hospital of Twin Cities of Pakistan[NCT05011032] | 0 participants (Actual) | Interventional | 2021-08-12 | Withdrawn (stopped due to Ethical approval was not done. Hence the funding was withhold.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 reviews available for hydrogen sulfide and Hyperhomocysteinemia
| Article | Year |
|---|---|
Sulfur-Containing Amino Acids and Lipid Metabolism.
Topics: Amino Acids, Sulfur; Animals; Atherosclerosis; Betaine; Cholesterol; Cysteine; Dietary Proteins; Die | 2020 |
Hyperhomocysteinemia and Cardiovascular Disease: Is the Adenosinergic System the Missing Link?
Topics: Animals; Cardiovascular Diseases; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Rece | 2021 |
The Contribution of Homocysteine Metabolism Disruption to Endothelial Dysfunction: State-of-the-Art.
Topics: Atherosclerosis; Cardiovascular Diseases; Endothelial Cells; Homocysteine; Humans; Hydrogen Sulfide; | 2019 |
Disturbed homocysteine metabolism is associated with cancer.
Topics: Alleles; Animals; Cystathionine beta-Synthase; Disease Susceptibility; Folic Acid; Genetic Predispos | 2019 |
[Cystathionine γ-lyase].
Topics: Animals; Cystathionine gamma-Lyase; Cysteine; Gene Expression; Glutathione; Humans; Hydrogen Sulfide | 2014 |
Hydrogen sulfide and endothelial dysfunction: relationship with nitric oxide.
Topics: Animals; Endothelium, Vascular; Hydrogen Sulfide; Hyperhomocysteinemia; Mice; Mice, Knockout; Nitric | 2014 |
The Sulfur Metabolite Lanthionine: Evidence for a Role as a Novel Uremic Toxin.
Topics: Alanine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Homocysteine; Humans; Hydrogen Sulf | 2017 |
Homocysteine to hydrogen sulfide or hypertension.
Topics: Calcium; Collagen; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Hypertension; Muscl | 2010 |
Endogenous hydrogen sulfide is involved in the pathogenesis of atherosclerosis.
Topics: Atherosclerosis; Blood Platelets; Calcinosis; Cell Proliferation; Humans; Hydrogen Sulfide; Hyperhom | 2010 |
Hydrogen sulfide, the third gaseous signaling molecule with cardiovascular properties, is decreased in hemodialysis patients.
Topics: Cardiovascular Diseases; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Humans; Hydrogen Su | 2010 |
[Role of hydrogen sulfide in chronic kidney disease and diabetic nephropathy].
Topics: Animals; Chronic Disease; Diabetic Nephropathies; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Hy | 2012 |
[Hydrogen sulfide as a biologically active mediator in the cardiovascular system].
Topics: Alzheimer Disease; Animals; Brain; Cardiovascular System; Cyclic AMP; Cystathionine beta-Synthase; D | 2004 |
[A new strategy to treat hyperhomocysteinemia].
Topics: Animals; Cardiovascular Diseases; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Metallothionein; T | 2005 |
1 trial available for hydrogen sulfide and Hyperhomocysteinemia
| Article | Year |
|---|---|
Divergent behavior of hydrogen sulfide pools and of the sulfur metabolite lanthionine, a novel uremic toxin, in dialysis patients.
Topics: Adult; Aged; Alanine; Female; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Male; Middle Aged; Ren | 2016 |
33 other studies available for hydrogen sulfide and Hyperhomocysteinemia
| Article | Year |
|---|---|
Homozygous whole body Cbs knockout in adult mice features minimal pathology during ageing despite severe homocysteinemia.
Topics: Aging; Alopecia; Animals; Cystathionine beta-Synthase; Disease Models, Animal; Female; Homocystinuri | 2022 |
Endogenous H
Topics: Animals; Cerebral Hemorrhage; Cystathionine beta-Synthase; Erythrocytes; Gasotransmitters; Hematoma; | 2022 |
Hydrogen sulfide attenuates hyperhomocysteinemia-induced mitochondrial dysfunctions in brain.
Topics: Animals; Apoptosis; Biomarkers; Electron Transport; Glutathione; Humans; Hydrogen Sulfide; Hyperhomo | 2020 |
INFLUENCE OF CHRONIC HYPERHOMOCYSTEINEMIA ON METABOLISM OF SULFUR CONTAINING AMINO ACIDS IN THE RATS' HEART AND BRAIN ON THE BACKGROUND OF HYPERTHYREOSIS AND HYPOTHYREOSIS.
Topics: Amino Acids; Animals; Brain; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia; Male; Myocardium; | 2019 |
Hydrogen Sulfide Alleviates Anxiety, Motor, and Cognitive Dysfunctions in Rats with Maternal Hyperhomocysteinemia via Mitigation of Oxidative Stress.
Topics: Animals; Anxiety; Cognitive Dysfunction; Cystathionine beta-Synthase; Female; Homocysteine; Hydrogen | 2020 |
Hydrogen sulfide attenuates hyperhomocysteinemia-induced blood-brain barrier permeability by inhibiting MMP-9.
Topics: Animals; Blood-Brain Barrier; Coloring Agents; Evans Blue; Fluorescein; Gelatin; Homocysteine; Hydro | 2022 |
Exogenous hydrogen sulfide inhibits neutrophils extracellular traps formation via the HMGB1/TLR4/p-38 MAPK/ROS axis in hyperhomocysteinemia rats.
Topics: Animals; Blood Platelets; Disease Models, Animal; Extracellular Traps; HMGB1 Protein; Hydrogen Sulfi | 2021 |
Hydrogen sulphide reduces hyperhomocysteinaemia-induced endothelial ER stress by sulfhydrating protein disulphide isomerase to attenuate atherosclerosis.
Topics: Animals; Atherosclerosis; Cell Line; Disease Models, Animal; Endoplasmic Reticulum Stress; Endotheli | 2021 |
Analysis of MTHFR, CBS, Glutathione, Taurine, and Hydrogen Sulfide Levels in Retinas of Hyperhomocysteinemic Mice.
Topics: Animals; Disease Models, Animal; Gene Expression Regulation; Glutathione; Hydrogen Sulfide; Hyperhom | 2017 |
Hydrogen sulfide attenuates homocysteine-induced cognitive deficits and neurochemical alterations by improving endogenous hydrogen sulfide levels.
Topics: Animals; Cerebral Cortex; Cognition; Cognitive Dysfunction; Cystathionine beta-Synthase; Cystathioni | 2017 |
The Hydrogen Sulfide-Vitamin B12-Folic Acid Axis: An Intriguing Issue in Chronic Kidney Disease. A Comment on Toohey JI: "Possible Involvement of Hydrosulfide in B12-Dependent Methyl Group Transfer". Molecules 2017, 22, 582, pii: E582.
Topics: Folic Acid; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Renal Insufficiency, Chronic; Vitamin B | 2017 |
Hydrogen sulfide epigenetically mitigates bone loss through OPG/RANKL regulation during hyperhomocysteinemia in mice.
Topics: Animals; Bone Diseases, Metabolic; Epigenomics; Female; Hydrogen Sulfide; Hyperhomocysteinemia; Mice | 2018 |
Exogenous hydrogen sulfide protects from endothelial cell damage, platelet activation, and neutrophils extracellular traps formation in hyperhomocysteinemia rats.
Topics: Animals; Blood Platelets; Cells, Cultured; Endothelial Cells; Extracellular Traps; Hydrogen Sulfide; | 2018 |
Hydrogen Sulfide Promotes Bone Homeostasis by Balancing Inflammatory Cytokine Signaling in CBS-Deficient Mice through an Epigenetic Mechanism.
Topics: Acetylation; Animals; Bone Remodeling; Chromatin; Core Binding Factor Alpha 1 Subunit; Cystathionine | 2018 |
Hydrogen Sulfide Ameliorates Developmental Impairments of Rat Offspring with Prenatal Hyperhomocysteinemia.
Topics: Animals; Antioxidants; Brain; Female; Glutathione Peroxidase; Homocysteine; Hydrogen Sulfide; Hyperh | 2018 |
Hydrogen sulfide lowers hyperhomocysteinemia dependent on cystathionine γ lyase S-sulfhydration in ApoE-knockout atherosclerotic mice.
Topics: Animals; Atherosclerosis; Cells, Cultured; Cystathionine gamma-Lyase; Disease Models, Animal; Dose-R | 2019 |
Hydrogen sulphide pathway contributes to the enhanced human platelet aggregation in hyperhomocysteinemia.
Topics: Adenosine Triphosphate; Arachidonic Acid; Blood Platelets; Cyclic AMP; Cystathionine beta-Synthase; | 2013 |
Hydrogen sulfide inhibits homocysteine-induced endoplasmic reticulum stress and neuronal apoptosis in rat hippocampus via upregulation of the BDNF-TrkB pathway.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Line; Endoplasmic Reticulum Stress; Hipp | 2014 |
Hydrogen Sulfide Epigenetically Attenuates Homocysteine-Induced Mitochondrial Toxicity Mediated Through NMDA Receptor in Mouse Brain Endothelial (bEnd3) Cells.
Topics: Animals; Brain; Endothelial Cells; Epigenesis, Genetic; Homocysteine; Hydrogen Sulfide; Hyperhomocys | 2015 |
Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis.
Topics: Animals; Colitis; Colon; Dextran Sulfate; Diet; Disease Progression; Humans; Hydrogen Sulfide; Hyper | 2014 |
Hyperhomocysteinemia abrogates fasting-induced cardioprotection against ischemia/reperfusion by limiting bioavailability of hydrogen sulfide anions.
Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Fasting; Humans; Hydrogen Sulfide; | 2015 |
Hydrogen sulfide mitigates homocysteine-mediated pathological remodeling by inducing miR-133a in cardiomyocytes.
Topics: Animals; Gene Expression Regulation; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; M | 2015 |
Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter.
Topics: Animals; Cells, Cultured; Cystathionine gamma-Lyase; DNA (Cytosine-5-)-Methyltransferases; DNA Methy | 2015 |
High homocysteine levels prevent via H2 S the CoCl2 -induced alteration of lymphocyte viability.
Topics: Adenosine; Adult; Alkynes; Cell Hypoxia; Cell Survival; Cobalt; Glycine; Homocysteine; Humans; Hydro | 2016 |
H2S biogenesis by human cystathionine gamma-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia.
Topics: Alanine; Catalysis; Cystathionine gamma-Lyase; Cysteine; Dose-Response Relationship, Drug; Humans; H | 2009 |
Hydrogen sulfide ameliorates hyperhomocysteinemia-associated chronic renal failure.
Topics: Animals; Antioxidants; Apoptosis; Cystathionine beta-Synthase; Desmin; Disease Models, Animal; Gluta | 2009 |
Hydrogen sulfide attenuates hyperhomocysteinemia-induced cardiomyocytic endoplasmic reticulum stress in rats.
Topics: Animals; Caspase 12; Endoplasmic Reticulum; Heat-Shock Proteins; Hydrogen Sulfide; Hyperhomocysteine | 2010 |
Hydrogen sulfide mitigates matrix metalloproteinase-9 activity and neurovascular permeability in hyperhomocysteinemic mice.
Topics: Animals; Capillary Permeability; Hydrogen Sulfide; Hyperhomocysteinemia; Matrix Metalloproteinase 9; | 2010 |
Hydrogen sulfide regulates homocysteine-mediated glomerulosclerosis.
Topics: Animals; Collagen; Cystathionine beta-Synthase; Down-Regulation; Homocysteine; Hydrogen Sulfide; Hyp | 2010 |
Increased endogenous H2S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia.
Topics: Animals; Cells, Cultured; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Endostatins; Forkh | 2012 |
Don't forget about hydrogen sulphide.
Topics: Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Thrombosis | 2004 |
The methionine connection: homocysteine and hydrogen sulfide exert opposite effects on hepatic microcirculation in rats.
Topics: Acetylcholine; Animals; Disease Models, Animal; Homocysteine; Hydrogen Sulfide; Hyperhomocysteinemia | 2008 |
Evaluation of an enzymatic method to measure total homocysteine in plasma.
Topics: Blood Preservation; Chromatography, High Pressure Liquid; Cryopreservation; Fasting; Homocysteine; H | 2002 |