hydrogen sulfide has been researched along with Heart Disease, Ischemic in 32 studies
Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydrogen sulfide (H2S) is an attractive agent for myocardial ischemia-reperfusion injury, however, systemic delivery of H2S may cause unwanted side effects." | 7.83 | Delivery of Hydrogen Sulfide by Ultrasound Targeted Microbubble Destruction Attenuates Myocardial Ischemia-reperfusion Injury. ( Bin, J; Cao, S; Chen, G; Cui, K; Huang, Q; Kutty, S; Liao, W; Liao, Y; Wang, Y; Wu, J; Xiu, J; Yang, L; Zhang, W; Zhong, L, 2016) |
| "To investigate the effect of hydrogen sulfide (H2S) on mitochondrial function in acute myocardial ischemia in rats." | 7.77 | [Effects of hydrogen sulfide on myocardial mitochondrial injury during acute myocardial ischemia in rats]. ( Ding, YY; Li, LF; Liu, F; Zhang, JX; Zhang, QZ; Zhang, XY, 2011) |
| "The role of hydrogen sulfide (H(2)S) in myocardial infarction (MI) has not been previously studied." | 7.74 | Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats. ( Ho, P; Huang, SH; Loke, YY; Lu, J; Moore, PK; Tan, CS; Wang, ZJ; Whiteman, M; Zhu, YC; Zhu, YZ, 2007) |
| "We investigated whether (endogenous) hydrogen sulfide (H2S) protects the heart against myocardial ischemia and reperfusion injury." | 7.73 | The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat. ( McDonald, MC; Sivarajah, A; Thiemermann, C, 2006) |
| "Ischemic heart disease is one of the major causes of cardiovascular‑related mortality worldwide." | 6.72 | Cardioprotective effects of hydrogen sulfide in attenuating myocardial ischemia‑reperfusion injury (Review). ( Gu, Y; Wu, D; Zhu, D, 2021) |
| "Hydrogen sulfide (H(2)S) is an endogenous signaling molecule with potent cytoprotective effects." | 5.36 | Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice. ( Calvert, JW; Elrod, JW; Elston, M; Gundewar, S; Jha, S; Lefer, DJ; Nicholson, CK; Ramachandran, A, 2010) |
| "Hydrogen sulfide (H2S) is a gaseous mediator, produced by the metabolic pathways that regulate tissue concentrations of sulfur-containing amino acids." | 5.33 | Exogenous hydrogen sulfide (H2S) protects against regional myocardial ischemia-reperfusion injury--Evidence for a role of K ATP channels. ( Baxter, GF; Johansen, D; Ytrehus, K, 2006) |
| "Hydrogen sulfide (H2S) is an attractive agent for myocardial ischemia-reperfusion injury, however, systemic delivery of H2S may cause unwanted side effects." | 3.83 | Delivery of Hydrogen Sulfide by Ultrasound Targeted Microbubble Destruction Attenuates Myocardial Ischemia-reperfusion Injury. ( Bin, J; Cao, S; Chen, G; Cui, K; Huang, Q; Kutty, S; Liao, W; Liao, Y; Wang, Y; Wu, J; Xiu, J; Yang, L; Zhang, W; Zhong, L, 2016) |
| "Bioavailability of nitric oxide (NO) and hydrogen sulfide (H2S) is reduced in heart failure (HF)." | 3.83 | Nitrite Therapy Ameliorates Myocardial Dysfunction via H2S and Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2)-Dependent Signaling in Chronic Heart Failure. ( Bhushan, S; Bradley, JM; Donnarumma, E; Donnelly, EL; Islam, KN; Lefer, DJ; Otsuka, H, 2016) |
| "To investigate the effect of hydrogen sulfide (H2S) on mitochondrial function in acute myocardial ischemia in rats." | 3.77 | [Effects of hydrogen sulfide on myocardial mitochondrial injury during acute myocardial ischemia in rats]. ( Ding, YY; Li, LF; Liu, F; Zhang, JX; Zhang, QZ; Zhang, XY, 2011) |
| "In this study, we determined the cardioprotective effects of S-propargyl-cysteine (SPRC), a structural analog of S-allylcysteine (SAC), using in vivo models of acute myocardial infarction (MI) and in vitro hypoxic cardiomyocytes models." | 3.75 | S-propargyl-cysteine protects both adult rat hearts and neonatal cardiomyocytes from ischemia/hypoxia injury: the contribution of the hydrogen sulfide-mediated pathway. ( Liu, HR; Mu, Q; Rose, P; Wang, Q; Zhu, YZ, 2009) |
| "The role of hydrogen sulfide (H(2)S) in myocardial infarction (MI) has not been previously studied." | 3.74 | Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats. ( Ho, P; Huang, SH; Loke, YY; Lu, J; Moore, PK; Tan, CS; Wang, ZJ; Whiteman, M; Zhu, YC; Zhu, YZ, 2007) |
| "We investigated whether (endogenous) hydrogen sulfide (H2S) protects the heart against myocardial ischemia and reperfusion injury." | 3.73 | The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat. ( McDonald, MC; Sivarajah, A; Thiemermann, C, 2006) |
| "Ischemic heart disease is one of the major causes of cardiovascular‑related mortality worldwide." | 2.72 | Cardioprotective effects of hydrogen sulfide in attenuating myocardial ischemia‑reperfusion injury (Review). ( Gu, Y; Wu, D; Zhu, D, 2021) |
| "Carbon monoxide (CO) is a gaseous product generated by heme oxygenase (HO), which oxidatively degrades heme." | 2.48 | Carbon monoxide: impact on remethylation/transsulfuration metabolism and its pathophysiologic implications. ( Hishiki, T; Kajimura, M; Kubo, A; Morikawa, T; Suematsu, M; Yamamoto, T, 2012) |
| "Hydrogen sulfide (H2S) is a gaseous signaling molecule that regulates cardiovascular function." | 1.42 | miRNA-30 family inhibition protects against cardiac ischemic injury by regulating cystathionine-γ-lyase expression. ( Guo, W; Lin, S; Miao, L; Shen, Y; Shen, Z; Xin, X; Zhu, Y; Zhu, YZ, 2015) |
| "Hydrogen sulfide (H( 2)S) is a biological mediator produced by enzyme-regulated pathways from L-cysteine, which is a substrate for cystathionine-gamma-lyase (CSE)." | 1.36 | L-cysteine stimulates hydrogen sulfide synthesis in myocardium associated with attenuation of ischemia-reperfusion injury. ( Baxter, GF; Elsey, DJ; Fowkes, RC, 2010) |
| "Hydrogen sulfide (H(2)S) is an endogenous signaling molecule with potent cytoprotective effects." | 1.36 | Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice. ( Calvert, JW; Elrod, JW; Elston, M; Gundewar, S; Jha, S; Lefer, DJ; Nicholson, CK; Ramachandran, A, 2010) |
| "Hydrogen sulfide (H2S) is a gaseous mediator, produced by the metabolic pathways that regulate tissue concentrations of sulfur-containing amino acids." | 1.33 | Exogenous hydrogen sulfide (H2S) protects against regional myocardial ischemia-reperfusion injury--Evidence for a role of K ATP channels. ( Baxter, GF; Johansen, D; Ytrehus, K, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (15.63) | 29.6817 |
| 2010's | 25 (78.13) | 24.3611 |
| 2020's | 2 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, D | 1 |
| Gu, Y | 1 |
| Zhu, D | 1 |
| Hsieh, MH | 1 |
| Tsai, HW | 1 |
| Lin, KJ | 1 |
| Wu, ZY | 1 |
| Hu, HY | 1 |
| Chang, Y | 1 |
| Wei, HJ | 1 |
| Sung, HW | 1 |
| Chen, Y | 2 |
| Zhang, F | 1 |
| Yin, J | 1 |
| Wu, S | 1 |
| Zhou, X | 1 |
| Takatani-Nakase, T | 1 |
| Katayama, M | 1 |
| Matsui, C | 1 |
| Hanaoka, K | 1 |
| van der Vlies, AJ | 1 |
| Takahashi, K | 1 |
| Nakase, I | 1 |
| Hasegawa, U | 1 |
| Bai, YD | 2 |
| Yang, YR | 1 |
| Mu, XP | 1 |
| Lin, G | 1 |
| Wang, YP | 1 |
| Jin, S | 2 |
| Wang, MJ | 2 |
| Zhu, YC | 3 |
| Wang, W | 1 |
| Liu, H | 1 |
| Lu, Y | 1 |
| Wang, X | 1 |
| Zhang, B | 1 |
| Cong, S | 1 |
| Zhao, Y | 3 |
| Ji, M | 1 |
| Tao, H | 1 |
| Wei, L | 1 |
| Casalini, ED | 1 |
| Goodwill, AG | 1 |
| Owen, MK | 1 |
| Moberly, SP | 1 |
| Berwick, ZC | 1 |
| Tune, JD | 1 |
| Kan, J | 1 |
| Guo, W | 2 |
| Huang, C | 1 |
| Bao, G | 1 |
| Zhu, Y | 2 |
| Zhu, YZ | 6 |
| Zhang, Y | 1 |
| Li, H | 3 |
| Zhao, G | 1 |
| Sun, A | 1 |
| Zong, NC | 1 |
| Li, Z | 1 |
| Zhu, H | 1 |
| Zou, Y | 1 |
| Yang, X | 1 |
| Ge, J | 1 |
| Toldo, S | 1 |
| Das, A | 1 |
| Mezzaroma, E | 1 |
| Chau, VQ | 1 |
| Marchetti, C | 1 |
| Durrant, D | 1 |
| Samidurai, A | 1 |
| Van Tassell, BW | 1 |
| Yin, C | 1 |
| Ockaili, RA | 1 |
| Vigneshwar, N | 1 |
| Mukhopadhyay, ND | 1 |
| Kukreja, RC | 1 |
| Abbate, A | 1 |
| Salloum, FN | 1 |
| Dudek, M | 1 |
| Knutelska, J | 1 |
| Bednarski, M | 1 |
| Nowiński, L | 1 |
| Zygmunt, M | 1 |
| Bilska-Wilkosz, A | 1 |
| Iciek, M | 1 |
| Otto, M | 1 |
| Żytka, I | 1 |
| Sapa, J | 1 |
| Włodek, L | 1 |
| Filipek, B | 1 |
| Andreadou, I | 2 |
| Iliodromitis, EK | 2 |
| Rassaf, T | 1 |
| Schulz, R | 1 |
| Papapetropoulos, A | 2 |
| Ferdinandy, P | 1 |
| Shen, Y | 1 |
| Shen, Z | 1 |
| Miao, L | 1 |
| Xin, X | 1 |
| Lin, S | 1 |
| Penna, C | 1 |
| Granata, R | 1 |
| Tocchetti, CG | 1 |
| Gallo, MP | 1 |
| Alloatti, G | 1 |
| Pagliaro, P | 1 |
| Wei, C | 1 |
| Wang, L | 1 |
| Peng, X | 1 |
| He, Y | 1 |
| Shao, H | 1 |
| Zhong, X | 1 |
| Xu, C | 1 |
| Wen, YD | 1 |
| Lougiakis, N | 1 |
| Gikas, E | 1 |
| Toumpas, S | 1 |
| Efentakis, P | 1 |
| Wedmann, R | 1 |
| Zoga, A | 1 |
| Zhou, Z | 1 |
| Skaltsounis, AL | 1 |
| Filipovic, MR | 1 |
| Pouli, N | 1 |
| Marakos, P | 1 |
| Shimizu, Y | 1 |
| Nicholson, CK | 2 |
| Lambert, JP | 1 |
| Barr, LA | 1 |
| Kuek, N | 1 |
| Herszenhaut, D | 1 |
| Tan, L | 1 |
| Murohara, T | 1 |
| Hansen, JM | 1 |
| Husain, A | 1 |
| Naqvi, N | 1 |
| Calvert, JW | 2 |
| Li, N | 1 |
| Hou, CL | 1 |
| Ma, FF | 1 |
| Li, XH | 1 |
| Wang, J | 1 |
| Hu, X | 1 |
| Jiang, H | 1 |
| Chen, G | 1 |
| Yang, L | 1 |
| Zhong, L | 1 |
| Kutty, S | 1 |
| Wang, Y | 1 |
| Cui, K | 1 |
| Xiu, J | 1 |
| Cao, S | 1 |
| Huang, Q | 1 |
| Liao, W | 1 |
| Liao, Y | 1 |
| Wu, J | 1 |
| Zhang, W | 1 |
| Bin, J | 1 |
| Donnarumma, E | 1 |
| Bhushan, S | 1 |
| Bradley, JM | 1 |
| Otsuka, H | 1 |
| Donnelly, EL | 1 |
| Lefer, DJ | 2 |
| Islam, KN | 1 |
| Wang, Q | 2 |
| Liu, HR | 2 |
| Mu, Q | 1 |
| Rose, P | 2 |
| Wang, XL | 1 |
| Elsey, DJ | 1 |
| Fowkes, RC | 1 |
| Baxter, GF | 2 |
| Elston, M | 1 |
| Gundewar, S | 1 |
| Jha, S | 1 |
| Elrod, JW | 1 |
| Ramachandran, A | 1 |
| Liu, F | 1 |
| Zhang, JX | 1 |
| Li, LF | 1 |
| Zhang, QZ | 1 |
| Ding, YY | 1 |
| Zhang, XY | 1 |
| Hishiki, T | 1 |
| Yamamoto, T | 1 |
| Morikawa, T | 1 |
| Kubo, A | 1 |
| Kajimura, M | 1 |
| Suematsu, M | 1 |
| Geng, B | 1 |
| Chang, L | 1 |
| Pan, C | 1 |
| Qi, Y | 1 |
| Zhao, J | 1 |
| Pang, Y | 1 |
| Du, J | 1 |
| Tang, C | 1 |
| Johansen, D | 1 |
| Ytrehus, K | 1 |
| Sivarajah, A | 1 |
| McDonald, MC | 1 |
| Thiemermann, C | 1 |
| Wang, ZJ | 1 |
| Ho, P | 1 |
| Loke, YY | 1 |
| Huang, SH | 1 |
| Tan, CS | 1 |
| Whiteman, M | 1 |
| Lu, J | 1 |
| Moore, PK | 1 |
6 reviews available for hydrogen sulfide and Heart Disease, Ischemic
| Article | Year |
|---|---|
Cardioprotective effects of hydrogen sulfide in attenuating myocardial ischemia‑reperfusion injury (Review).
Topics: Animals; Cardiotonic Agents; Heart; Humans; Hydrogen Sulfide; Ischemic Postconditioning; Myocardial | 2021 |
Protective mechanisms of hydrogen sulfide in myocardial ischemia.
Topics: Animals; Cardiovascular Diseases; Cystathionine gamma-Lyase; Humans; Hydrogen Sulfide; Mitochondria; | 2020 |
The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning.
Topics: Animals; Cardiotonic Agents; Gasotransmitters; Humans; Hydrogen Sulfide; Ischemic Postconditioning; | 2015 |
Endogenous Cardioprotective Agents: Role in Pre and Postconditioning.
Topics: Animals; Carbon Monoxide; Cardiotonic Agents; Gasotransmitters; Humans; Hydrogen Sulfide; Ischemic P | 2015 |
The Pharmacological Effects of S-Propargyl-Cysteine, a Novel Endogenous H2S-Producing Compound.
Topics: Animals; Chemistry, Pharmaceutical; Cysteine; Heart Failure; Humans; Hydrogen Sulfide; Myocardial Is | 2015 |
Carbon monoxide: impact on remethylation/transsulfuration metabolism and its pathophysiologic implications.
Topics: Carbon Monoxide; Cystathionine beta-Synthase; Heme Oxygenase (Decyclizing); Humans; Hydrogen Sulfide | 2012 |
26 other studies available for hydrogen sulfide and Heart Disease, Ischemic
| Article | Year |
|---|---|
An in situ slow-releasing H
Topics: Allyl Compounds; Animals; Antioxidants; Apoptosis; Cardiotonic Agents; Cell Line; Delayed-Action Pre | 2019 |
Hydrogen sulfide donor micelles protect cardiomyocytes from ischemic cell death.
Topics: Animals; Cell Death; Cell Survival; Cells, Cultured; Humans; Hydrogen Sulfide; Micelles; Myocardial | 2017 |
Hydrogen Sulfide Alleviates Acute Myocardial Ischemia Injury by Modulating Autophagy and Inflammation Response under Oxidative Stress.
Topics: Acute Disease; Animals; Hydrogen Sulfide; Male; Mice; Mice, Knockout; Myocardial Ischemia; Oxidative | 2018 |
Controlled-releasing hydrogen sulfide donor based on dual-modal iron oxide nanoparticles protects myocardial tissue from ischemia-reperfusion injury.
Topics: Allyl Compounds; Animals; Cardiotonic Agents; Cell Line; Delayed-Action Preparations; Ferric Compoun | 2019 |
Contribution of hydrogen sulfide to the control of coronary blood flow.
Topics: Animals; Blood Flow Velocity; Coronary Circulation; Dogs; Female; Gasotransmitters; Hydrogen Sulfide | 2014 |
S-propargyl-cysteine, a novel water-soluble modulator of endogenous hydrogen sulfide, promotes angiogenesis through activation of signal transducer and activator of transcription 3.
Topics: Active Transport, Cell Nucleus; Angiogenesis Inducing Agents; Animals; Cell Adhesion; Cell Movement; | 2014 |
Hydrogen sulfide attenuates the recruitment of CD11b⁺Gr-1⁺ myeloid cells and regulates Bax/Bcl-2 signaling in myocardial ischemia injury.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; bcl-2-Associated X Protein; CD11b Antigen; Cell Moveme | 2014 |
Induction of microRNA-21 with exogenous hydrogen sulfide attenuates myocardial ischemic and inflammatory injury in mice.
Topics: Animals; Cells, Cultured; Humans; Hydrogen Sulfide; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Myoca | 2014 |
Alpha lipoic acid protects the heart against myocardial post ischemia-reperfusion arrhythmias via KATP channel activation in isolated rat hearts.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Antioxidants; Arrhythmias, C | 2014 |
miRNA-30 family inhibition protects against cardiac ischemic injury by regulating cystathionine-γ-lyase expression.
Topics: Animals; Base Sequence; Binding Sites; Cystathionine gamma-Lyase; Enzyme Repression; HEK293 Cells; H | 2015 |
H2 S restores the cardioprotection from ischemic post-conditioning in isolated aged rat hearts.
Topics: Aging; Animals; Cardiotonic Agents; Heart; Hydrogen Sulfide; Ischemic Postconditioning; Myocardial I | 2015 |
Synthesis and Pharmacological Evaluation of Novel Adenine-Hydrogen Sulfide Slow Release Hybrids Designed as Multitarget Cardioprotective Agents.
Topics: Adenine; Animals; Blood Pressure; Cardiotonic Agents; Drug Design; Heart Rate; Hydrogen Sulfide; Mal | 2016 |
Sodium Sulfide Attenuates Ischemic-Induced Heart Failure by Enhancing Proteasomal Function in an Nrf2-Dependent Manner.
Topics: Animals; Cardiovascular Agents; Disease Models, Animal; Endoplasmic Reticulum Stress; Heart Failure; | 2016 |
The H2S Donor NaHS Changes the Expression Pattern of H2S-Producing Enzymes after Myocardial Infarction.
Topics: Animals; Cell Hypoxia; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cytoprotection; Hydro | 2016 |
ER stress-induced apoptosis: A novel therapeutic target in myocardial ischemia and reperfusion injury.
Topics: Apoptosis; Endoplasmic Reticulum Stress; Humans; Hydrogen Sulfide; Myocardial Ischemia; Myocardial R | 2016 |
Delivery of Hydrogen Sulfide by Ultrasound Targeted Microbubble Destruction Attenuates Myocardial Ischemia-reperfusion Injury.
Topics: Animals; Disease Models, Animal; Drug Delivery Systems; Hydrogen Sulfide; Lung; Microbubbles; Myocar | 2016 |
Nitrite Therapy Ameliorates Myocardial Dysfunction via H2S and Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2)-Dependent Signaling in Chronic Heart Failure.
Topics: Animals; Antioxidants; Cardiotonic Agents; Coronary Occlusion; Heart Failure; Hydrogen Sulfide; Male | 2016 |
S-propargyl-cysteine protects both adult rat hearts and neonatal cardiomyocytes from ischemia/hypoxia injury: the contribution of the hydrogen sulfide-mediated pathway.
Topics: Animals; Animals, Newborn; Cell Hypoxia; Cell Survival; Cystathionine gamma-Lyase; Cysteine; Disease | 2009 |
Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H(2)S production.
Topics: Air Pollutants; Animals; Antioxidants; Cardiotonic Agents; Catalase; Cysteine; Glutathione Peroxidas | 2010 |
L-cysteine stimulates hydrogen sulfide synthesis in myocardium associated with attenuation of ischemia-reperfusion injury.
Topics: Alkynes; Analysis of Variance; Animals; Cysteine; Disease Models, Animal; Drug Therapy, Combination; | 2010 |
Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice.
Topics: Animals; Body Weight; Cardiomegaly; Cystathionine gamma-Lyase; Gene Expression Regulation, Enzymolog | 2010 |
[Effects of hydrogen sulfide on myocardial mitochondrial injury during acute myocardial ischemia in rats].
Topics: Adenosine Triphosphatases; Animals; Glutathione Peroxidase; Hydrogen Sulfide; Lipid Peroxidation; Ma | 2011 |
Endogenous hydrogen sulfide regulation of myocardial injury induced by isoproterenol.
Topics: Alkenes; Animals; Carbon-Oxygen Lyases; Cardiotonic Agents; Creatine Kinase; Free Radical Scavengers | 2004 |
Exogenous hydrogen sulfide (H2S) protects against regional myocardial ischemia-reperfusion injury--Evidence for a role of K ATP channels.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Cardiac Output; Decanoic Acids; Glyburide; | 2006 |
The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat.
Topics: Alkynes; Animals; Cardiotonic Agents; Cystathionine gamma-Lyase; Decanoic Acids; Endotoxins; Enzyme | 2006 |
Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats.
Topics: Alkynes; Animals; Cell Death; Cells, Cultured; Culture Media; Cystathionine gamma-Lyase; Disease Mod | 2007 |