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hydrogen sulfide and Gastric Ulcer

hydrogen sulfide has been researched along with Gastric Ulcer in 15 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Research Excerpts

ExcerptRelevanceReference
"Studies have verified the protective effect of Hydrogen Sulfide (H2S) on gastric ulcer and ulcerative colitis, but the mechanisms are not fully illustrated."3.81Protective effect of hydrogen sulfide on TNF-α and IFN-γ-induced injury of intestinal epithelial barrier function in Caco-2 monolayers. ( Chen, GW; Chen, SW; Chen, ZY; Liu, YC; Pan, YS; Wang, PY; Wang, X; Zhang, JL; Zhu, J; Zuo, S, 2015)
" In the present study, we tested the effects (in rats) of a simple extract of medicinal cannabis (called "MFF") for its ability to promote resolution of colitis, to prevent gastric damage induced by naproxen, and to reduce gastric distention-induced visceral pain."3.79Pro-resolution, protective and anti-nociceptive effects of a cannabis extract in the rat gastrointestinal tract. ( Ferraz, JG; Flannigan, KL; McKnight, W; Tuitt, D; Wallace, JL; Wang, L, 2013)
"Hydrogen sulfide (H₂S) is an endogenous mediator, synthesized from l-cysteine by cystathionine γ-lyase (CSE), cystathionine β-synthase (CBS) or 3-mercaptopyruvate sulfurtransferase (3-MST)."1.46Exogenous and Endogenous Hydrogen Sulfide Protects Gastric Mucosa against the Formation and Time-Dependent Development of Ischemia/Reperfusion-Induced Acute Lesions Progressing into Deeper Ulcerations. ( Brzozowski, T; Ginter, G; Hubalewska-Mazgaj, M; Kwiecien, S; Magierowska, K; Magierowski, M; Pajdo, R; Sliwowski, Z, 2017)
"Pretreatment with naproxen in the WRS model caused an increase in severity of damage and a decrease in NOS activity."1.40Effects of conventional and hydrogen sulfide-releasing non-steroidal anti-inflammatory drugs in rats with stress-induced and epinephrine-induced gastric damage. ( Biletska, L; Bondarchuk, T; Fomenko, I; Panasyuk, N; Sklyarov, A; Wallace, JL, 2014)
"Hydrogen sulfide (H2S) is an endogenous gaseous mediator plays a potential role in modulating gastric inflammatory responses."1.39Protective effect of hydrogen sulfide against cold restraint stress-induced gastric mucosal injury in rats. ( Aboubakr, EM; El-Moselhy, MA; Hassan, MK; Taye, A, 2013)
"Hydrogen sulfide is an endogenous mediator that relaxes vascular smooth muscle, exhibits several antiinflammatory activities, and contributes to gastric mucosal defense."1.34Hydrogen sulfide enhances ulcer healing in rats. ( Dicay, M; Martin, GR; McKnight, W; Wallace, JL, 2007)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (26.67)29.6817
2010's10 (66.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Pineda-Peña, EA1
Orona-Ortiz, A1
Velázquez-Moyado, JA1
Tavares-Carvalho, JC1
Chávez-Piña, AE1
Balderas-López, JL1
Navarrete, A1
Bronowicka-Adamska, P1
Wróbel, M1
Magierowski, M3
Magierowska, K3
Kwiecień, S3
Brzozowski, T3
Wallace, JL5
Flannigan, KL1
McKnight, W2
Wang, L1
Ferraz, JG1
Tuitt, D1
Aboubakr, EM1
Taye, A1
El-Moselhy, MA1
Hassan, MK1
Fomenko, I1
Sklyarov, A1
Bondarchuk, T1
Biletska, L1
Panasyuk, N1
Diniz, PB1
Ribeiro, AR1
Estevam, CS1
Bani, CC1
Thomazzi, SM1
Chen, SW1
Zhu, J1
Zuo, S1
Zhang, JL1
Chen, ZY1
Chen, GW1
Wang, X1
Pan, YS1
Liu, YC1
Wang, PY1
Hubalewska-Mazgaj, M1
Sliwowski, Z1
Pajdo, R1
Ginter, G1
Caliendo, G1
Santagada, V1
Cirino, G1
Liu, L1
Cui, J1
Song, CJ1
Bian, JS1
Sparatore, A1
Soldato, PD1
Wang, XY1
Yan, CD1
Dicay, M1
Martin, GR1
Lou, LX1
Geng, B1
Du, JB1
Tang, CS1
Fiorucci, S1
Santucci, L1
Distrutti, E1

Reviews

3 reviews available for hydrogen sulfide and Gastric Ulcer

ArticleYear
Gaseous mediators nitric oxide and hydrogen sulfide in the mechanism of gastrointestinal integrity, protection and ulcer healing.
    Molecules (Basel, Switzerland), 2015, May-19, Volume: 20, Issue:5

    Topics: Animals; Gastric Mucosa; Humans; Hydrogen Sulfide; Nitric Oxide; Nitric Oxide Synthase; Stomach Ulce

2015
Building a better aspirin: gaseous solutions to a century-old problem.
    British journal of pharmacology, 2007, Volume: 152, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemistry, Pharmaceutical; Gastrointestinal Hemorr

2007
NSAIDs, coxibs, CINOD and H2S-releasing NSAIDs: what lies beyond the horizon.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2007, Volume: 39, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Disease Models, Animal;

2007

Other Studies

12 other studies available for hydrogen sulfide and Gastric Ulcer

ArticleYear
Anti-inflammatory, antioxidant, and gaso-protective mechanism of 3α-hydroxymasticadienoic acid and diligustilide combination on indomethacin gastric damage.
    Naunyn-Schmiedeberg's archives of pharmacology, 2020, Volume: 393, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Dinoprostone; Disease Models, An

2020
Hydrogen Sulphide Production in Healthy and Ulcerated Gastric Mucosa of Rats.
    Molecules (Basel, Switzerland), 2017, Mar-27, Volume: 22, Issue:4

    Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Disease Models, Animal; Gastric Muc

2017
Pro-resolution, protective and anti-nociceptive effects of a cannabis extract in the rat gastrointestinal tract.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2013, Volume: 64, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cannabis; Colitis; Gastrointestinal Tr

2013
Protective effect of hydrogen sulfide against cold restraint stress-induced gastric mucosal injury in rats.
    Archives of pharmacal research, 2013, Volume: 36, Issue:12

    Topics: Animals; Cold Temperature; Gastric Mucosa; Hydrogen Sulfide; Male; Protective Agents; Rats; Rats, Sp

2013
Effects of conventional and hydrogen sulfide-releasing non-steroidal anti-inflammatory drugs in rats with stress-induced and epinephrine-induced gastric damage.
    Stress (Amsterdam, Netherlands), 2014, Volume: 17, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Celecoxib; Disease Models, Animal; Epi

2014
Possible mechanisms of action of Caesalpinia pyramidalis against ethanol-induced gastric damage.
    Journal of ethnopharmacology, 2015, Jun-20, Volume: 168

    Topics: Animals; Anti-Ulcer Agents; Caesalpinia; Ethanol; Female; Gastric Mucosa; Hydrogen Sulfide; Interleu

2015
Protective effect of hydrogen sulfide on TNF-α and IFN-γ-induced injury of intestinal epithelial barrier function in Caco-2 monolayers.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2015, Volume: 64, Issue:10

    Topics: Biomarkers; Caco-2 Cells; Epithelium; Humans; Hydrogen Sulfide; Interferon-gamma; Intestinal Mucosa;

2015
Exogenous and Endogenous Hydrogen Sulfide Protects Gastric Mucosa against the Formation and Time-Dependent Development of Ischemia/Reperfusion-Induced Acute Lesions Progressing into Deeper Ulcerations.
    Molecules (Basel, Switzerland), 2017, Feb-15, Volume: 22, Issue:2

    Topics: Animals; Biomarkers; Disease Models, Animal; Disease Progression; Gastric Mucosa; Gene Expression; H

2017
Markedly reduced toxicity of a hydrogen sulphide-releasing derivative of naproxen (ATB-346).
    British journal of pharmacology, 2010, Volume: 159, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Blood Pressure; Cyclooxyg

2010
H(2)S-releasing aspirin protects against aspirin-induced gastric injury via reducing oxidative stress.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Aspirin; Cyclooxygenase 2; Delayed-Action Preparations; Dinoprostone; Disulfides; Dose-Resp

2012
Hydrogen sulfide enhances ulcer healing in rats.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2007, Volume: 21, Issue:14

    Topics: Acetic Acid; Animals; Hydrogen Sulfide; Intubation, Gastrointestinal; Male; Organothiophosphorus Com

2007
Hydrogen sulphide-induced hypothermia attenuates stress-related ulceration in rats.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Body Temperature; Caspase 12; Corticosterone; Disease Models,

2008