Page last updated: 2024-10-17

hydrogen sulfide and Endotoxin Shock

hydrogen sulfide has been researched along with Endotoxin Shock in 18 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Research Excerpts

ExcerptRelevanceReference
"To explore the changes of hydrogen sulfide (H(2)S) in vascular tissues of rats with septic shock and endotoxin shock and its possible pathophysiological implication."9.10Changes in arterial hydrogen sulfide (H(2)S) content during septic shock and endotoxin shock in rats. ( Bin, G; Du, J; Hui, Y; Jiang, H; Tang, C, 2003)
"To explore the role of hydrogen sulfide (H2S) in acute lung injury (ALI) during endotoxic shock (ES) and its relationship with nitric oxide (NO) and carbon monoxide (CO)."7.74[The role of hydrogen sulfide in acute lung injury during endotoxic shock and its relationship with nitric oxide and carbon monoxide]. ( Huang, XL; Ling, YL; Wei, P; Xian, XH; Zhou, XH, 2008)
"During resuscitated septic shock in swine with CAD, GYY4137 shifted metabolism to preferential carbohydrate utilization."5.46Metabolic, Cardiac, and Renal Effects of the Slow Hydrogen Sulfide-Releasing Molecule GYY4137 During Resuscitated Septic Shock in Swine with Pre-Existing Coronary Artery Disease. ( Calzia, E; Georgieff, M; Gröger, M; Hafner, S; Matallo, J; McCook, O; Nußbaum, BL; Radermacher, P; Vogt, J; Wachter, U; Wepler, M; Whiteman, M; Wood, ME, 2017)
"Hydrogen sulfide (H2S) is an important gaseous signaling agent mediated by many physiological processes and diseases."5.40Inorganic-organic hybrid nanoprobe for NIR-excited imaging of hydrogen sulfide in cell cultures and inflammation in a mouse model. ( Chen, W; Huang, L; Huang, W; Loo, JS; Pei, W; Wang, C; Yan, Q; Yao, C; Zhang, Q; Zhou, Y; Zhu, J, 2014)
"To explore the changes of hydrogen sulfide (H(2)S) in vascular tissues of rats with septic shock and endotoxin shock and its possible pathophysiological implication."5.10Changes in arterial hydrogen sulfide (H(2)S) content during septic shock and endotoxin shock in rats. ( Bin, G; Du, J; Hui, Y; Jiang, H; Tang, C, 2003)
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"Inhaling hydrogen sulfide (H2S) reduced energy expenditure resulting in hypothermia."3.77Inflammatory effects of hypothermia and inhaled H2S during resuscitated, hyperdynamic murine septic shock. ( Asfar, P; Calzia, E; Gebhard, F; Georgieff, M; Huber-Lang, M; Hysa, V; Knöferl, MW; Radermacher, P; Seitz, DH; Senftleben, U; Stahl, B; Wagner, F; Wagner, K; Weber, S, 2011)
"To explore the role of hydrogen sulfide (H2S) in acute lung injury (ALI) during endotoxic shock (ES) and its relationship with nitric oxide (NO) and carbon monoxide (CO)."3.74[The role of hydrogen sulfide in acute lung injury during endotoxic shock and its relationship with nitric oxide and carbon monoxide]. ( Huang, XL; Ling, YL; Wei, P; Xian, XH; Zhou, XH, 2008)
"We discuss the role of vasoplegia in these contexts and the criteria that are used to describe it are discussed."2.58Definitions and pathophysiology of vasoplegic shock. ( Creagh-Brown, BC; Forni, LG; Hunt, J; Lambden, S; Summers, C, 2018)
" Chronic administration of CSE inhibitor induces arterial hypertension in the rat."2.42[Hydrogen sulfide as a biologically active mediator in the cardiovascular system]. ( Bełtowski, J, 2004)
"Hemorrhagic shock was induced by bleeding the animals."1.48Time-Dependent Production of Endothelium-Related Biomarkers is Affected Differently in Hemorrhagic and Septic Shocks. ( Coskun, CN; Demirel-Yilmaz, E; Savci, V; Usanmaz, SE, 2018)
"During resuscitated septic shock in swine with CAD, GYY4137 shifted metabolism to preferential carbohydrate utilization."1.46Metabolic, Cardiac, and Renal Effects of the Slow Hydrogen Sulfide-Releasing Molecule GYY4137 During Resuscitated Septic Shock in Swine with Pre-Existing Coronary Artery Disease. ( Calzia, E; Georgieff, M; Gröger, M; Hafner, S; Matallo, J; McCook, O; Nußbaum, BL; Radermacher, P; Vogt, J; Wachter, U; Wepler, M; Whiteman, M; Wood, ME, 2017)
" (but not 1 mg/kg or 6 mg/kg), starting 24 h post-CLP, with dosing repeated every 6 h, improved the survival rate in CLP animals."1.43Delayed Treatment with Sodium Hydrosulfide Improves Regional Blood Flow and Alleviates Cecal Ligation and Puncture (CLP)-Induced Septic Shock. ( Ahmad, A; Druzhyna, N; Szabo, C, 2016)
"Hydrogen sulfide (H2S) is an important gaseous signaling agent mediated by many physiological processes and diseases."1.40Inorganic-organic hybrid nanoprobe for NIR-excited imaging of hydrogen sulfide in cell cultures and inflammation in a mouse model. ( Chen, W; Huang, L; Huang, W; Loo, JS; Pei, W; Wang, C; Yan, Q; Yao, C; Zhang, Q; Zhou, Y; Zhu, J, 2014)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (44.44)29.6817
2010's8 (44.44)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Merz, T1
Denoix, N1
Wigger, D1
Waller, C1
Wepler, M2
Vettorazzi, S1
Tuckermann, J1
Radermacher, P3
McCook, O2
Coskun, CN1
Usanmaz, SE1
Savci, V1
Demirel-Yilmaz, E1
Lambden, S1
Creagh-Brown, BC1
Hunt, J1
Summers, C1
Forni, LG1
Coletta, C1
Szabo, C2
Zhou, Y1
Chen, W1
Zhu, J1
Pei, W1
Wang, C1
Huang, L1
Yao, C1
Yan, Q1
Huang, W1
Loo, JS1
Zhang, Q1
Ahmad, A1
Druzhyna, N1
Tian, F1
Ling, Y1
Chen, Y1
Wang, Z1
Nußbaum, BL1
Vogt, J1
Wachter, U1
Matallo, J1
Calzia, E2
Gröger, M1
Georgieff, M2
Wood, ME1
Whiteman, M5
Hafner, S1
Huang, XL1
Zhou, XH1
Wei, P1
Xian, XH1
Ling, YL1
Li, L3
Moore, PK4
Salto-Tellez, M2
Tan, CH1
Wagner, F1
Wagner, K1
Weber, S1
Stahl, B1
Knöferl, MW1
Huber-Lang, M1
Seitz, DH1
Asfar, P1
Senftleben, U1
Gebhard, F1
Hysa, V1
Hui, Y1
Du, J1
Tang, C1
Bin, G1
Jiang, H1
Bełtowski, J1
Bhatia, M2
Zhu, YZ1
Zhu, YC1
Ramnath, RD1
Wang, ZJ1
Anuar, FB1
Jin, HF1
Du, JB1
Tang, CS1
Anuar, F1
Siau, JL1
Kwong, SE1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II Double Blind Randomized Controlled Trial of High Dose Vitamin B12 in Septic Shock[NCT03783091]Phase 220 participants (Anticipated)Interventional2019-08-05Recruiting
Postoperative Vasopressor Usage : a Prospective International Observational Study (SQUEEZE)[NCT03805230]40,000 participants (Anticipated)Observational2020-10-05Recruiting
Hydrogen Sulfide as Prognostic Factor[NCT01088490]50 participants (Actual)Observational2010-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for hydrogen sulfide and Endotoxin Shock

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Definitions and pathophysiology of vasoplegic shock.
    Critical care (London, England), 2018, 07-06, Volume: 22, Issue:1

    Topics: Anaphylaxis; Free Radicals; Humans; Hydrogen Sulfide; Prostaglandins; Shock, Septic; Vascular Resist

2018
Definitions and pathophysiology of vasoplegic shock.
    Critical care (London, England), 2018, 07-06, Volume: 22, Issue:1

    Topics: Anaphylaxis; Free Radicals; Humans; Hydrogen Sulfide; Prostaglandins; Shock, Septic; Vascular Resist

2018
Definitions and pathophysiology of vasoplegic shock.
    Critical care (London, England), 2018, 07-06, Volume: 22, Issue:1

    Topics: Anaphylaxis; Free Radicals; Humans; Hydrogen Sulfide; Prostaglandins; Shock, Septic; Vascular Resist

2018
Definitions and pathophysiology of vasoplegic shock.
    Critical care (London, England), 2018, 07-06, Volume: 22, Issue:1

    Topics: Anaphylaxis; Free Radicals; Humans; Hydrogen Sulfide; Prostaglandins; Shock, Septic; Vascular Resist

2018
Potential role of hydrogen sulfide in the pathogenesis of vascular dysfunction in septic shock.
    Current vascular pharmacology, 2013, Mar-01, Volume: 11, Issue:2

    Topics: Animals; Disease Models, Animal; Endothelium, Vascular; Humans; Hydrogen Sulfide; Muscle, Smooth, Va

2013
[Hydrogen sulfide as a biologically active mediator in the cardiovascular system].
    Postepy higieny i medycyny doswiadczalnej (Online), 2004, Jul-19, Volume: 58

    Topics: Alzheimer Disease; Animals; Brain; Cardiovascular System; Cyclic AMP; Cystathionine beta-Synthase; D

2004
[Significance of gaseous signal molecule in the pathogenesis of cardiovascular diseases].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2005, Volume: 27, Issue:4

    Topics: Animals; Carbon Monoxide; Cardiovascular Diseases; Humans; Hydrogen Sulfide; Hypertension; Hypertens

2005

Trials

2 trials available for hydrogen sulfide and Endotoxin Shock

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Changes in arterial hydrogen sulfide (H(2)S) content during septic shock and endotoxin shock in rats.
    The Journal of infection, 2003, Volume: 47, Issue:2

    Topics: Analysis of Variance; Animals; Arteries; Blood Glucose; Disease Models, Animal; Hemodynamics; Hydrog

2003

Other Studies

12 other studies available for hydrogen sulfide and Endotoxin Shock

ArticleYear
The Role of Glucocorticoid Receptor and Oxytocin Receptor in the Septic Heart in a Clinically Relevant, Resuscitated Porcine Model With Underlying Atherosclerosis.
    Frontiers in endocrinology, 2020, Volume: 11

    Topics: Animals; Atherosclerosis; Cystathionine gamma-Lyase; Disease Models, Animal; Gene Expression Regulat

2020
Time-Dependent Production of Endothelium-Related Biomarkers is Affected Differently in Hemorrhagic and Septic Shocks.
    Inflammation, 2018, Volume: 41, Issue:1

    Topics: Animals; Antioxidants; Arginine; Biomarkers; Blood Pressure; Disease Models, Animal; Endothelial Cel

2018
Inorganic-organic hybrid nanoprobe for NIR-excited imaging of hydrogen sulfide in cell cultures and inflammation in a mouse model.
    Small (Weinheim an der Bergstrasse, Germany), 2014, Dec-10, Volume: 10, Issue:23

    Topics: Animals; Carbocyanines; Coumarins; Disease Models, Animal; Fluorescent Dyes; HeLa Cells; Humans; Hyd

2014
Delayed Treatment with Sodium Hydrosulfide Improves Regional Blood Flow and Alleviates Cecal Ligation and Puncture (CLP)-Induced Septic Shock.
    Shock (Augusta, Ga.), 2016, Volume: 46, Issue:2

    Topics: Animals; Hydrogen Sulfide; Inflammation; Interleukin-5; Interleukin-6; Ligation; Male; Neutrophil In

2016
Effects of CCK-8 and Cystathionine γ-Lyase/Hydrogen Sulfide System on Acute Lung Injury in Rats.
    Inflammation, 2017, Volume: 40, Issue:1

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Cystathionine gamma-Lyase; Humans; Hydrogen Su

2017
Metabolic, Cardiac, and Renal Effects of the Slow Hydrogen Sulfide-Releasing Molecule GYY4137 During Resuscitated Septic Shock in Swine with Pre-Existing Coronary Artery Disease.
    Shock (Augusta, Ga.), 2017, Volume: 48, Issue:2

    Topics: Animals; Coronary Artery Disease; Delayed-Action Preparations; Disease Models, Animal; Heart; Hydrog

2017
[The role of hydrogen sulfide in acute lung injury during endotoxic shock and its relationship with nitric oxide and carbon monoxide].
    Zhonghua yi xue za zhi, 2008, Aug-19, Volume: 88, Issue:32

    Topics: Acute Lung Injury; Animals; Blood Pressure; Carbon Monoxide; Cystathionine gamma-Lyase; Heme Oxygena

2008
Dexamethasone inhibits lipopolysaccharide-induced hydrogen sulphide biosynthesis in intact cells and in an animal model of endotoxic shock.
    Journal of cellular and molecular medicine, 2009, Volume: 13, Issue:8B

    Topics: Animals; Blotting, Western; Cells, Cultured; Dexamethasone; Hydrogen Sulfide; Lipopolysaccharides; R

2009
GYY4137, a novel hydrogen sulfide-releasing molecule, protects against endotoxic shock in the rat.
    Free radical biology & medicine, 2009, Jul-01, Volume: 47, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Cell Line; Cyclooxygenase 2; Cytokines; Cytoprote

2009
Inflammatory effects of hypothermia and inhaled H2S during resuscitated, hyperdynamic murine septic shock.
    Shock (Augusta, Ga.), 2011, Volume: 35, Issue:4

    Topics: Animals; Chemokine CCL2; Chemokine CCL8; Chemokines; Electrophoretic Mobility Shift Assay; Heme Oxyg

2011
Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:9

    Topics: Alkynes; Animals; Extracellular Signal-Regulated MAP Kinases; Glycine; Hydrogen Sulfide; Inflammatio

2005
Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:9

    Topics: Alkynes; Animals; Extracellular Signal-Regulated MAP Kinases; Glycine; Hydrogen Sulfide; Inflammatio

2005
Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:9

    Topics: Alkynes; Animals; Extracellular Signal-Regulated MAP Kinases; Glycine; Hydrogen Sulfide; Inflammatio

2005
Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:9

    Topics: Alkynes; Animals; Extracellular Signal-Regulated MAP Kinases; Glycine; Hydrogen Sulfide; Inflammatio

2005
Nitric oxide-releasing flurbiprofen reduces formation of proinflammatory hydrogen sulfide in lipopolysaccharide-treated rat.
    British journal of pharmacology, 2006, Volume: 147, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cystathionine gamma-Lyase; Flurbiprofen; Hydrogen

2006