hydrogen sulfide has been researched along with Edema-Proteinuria-Hypertension Gestosis in 18 studies
Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our laboratory demonstrated that preeclampsia is associated with high soluble fms-like tyrosine kinase 1 (sFlt-1) and low heme oxygenase-1 (HO1/Hmox1) expression." | 5.62 | MZe786, a hydrogen sulfide-releasing aspirin prevents preeclampsia in heme oxygenase-1 haplodeficient pregnancy under high soluble flt-1 environment. ( Agrawal, S; Ahmad, S; Ahmed, A; Alzahrani, FA; Dias, IH; Rezai, H; Sanchez-Aranguren, L; Sparatore, A; Wang, K, 2021) |
| "In newborns born to mothers with preeclampsia, an increase in the concentration of hydrogen sulfide was detected in the blood, which is probably a compensatory reaction aimed at restoring vascular homeostasis during early postnatal adaptation." | 5.62 | Hydrogen sulfide content in pregnant women with preeclampsia in late gestation and their newborns. ( Baev, TO; Kharlamova, NV; Klycheva, MM; Kuzmenko, GN; Nazarov, SB; Panova, IA; Popova, IG; Sadov, RI; Sitnikova, OG; Veselkova, YN, 2021) |
| "Suramin treatment exerted negligible effect on the RAS pathway in the adult male offspring kidneys." | 5.43 | N-Acetylcysteine Prevents Programmed Hypertension in Male Rat Offspring Born to Suramin-Treated Mothers. ( Hsu, CN; Lee, CT; Lin, YJ; Tain, YL; Tsai, CC, 2016) |
| "The exact etiology of preeclampsia is unknown, but there is growing evidence of an imbalance in angiogenic growth factors and abnormal placentation." | 5.39 | Dysregulation of hydrogen sulfide producing enzyme cystathionine γ-lyase contributes to maternal hypertension and placental abnormalities in preeclampsia. ( Ahmad, S; Ahmed, A; Baily, J; Buhimschi, CS; Buhimschi, IA; Cai, M; Crispi, F; Cudmore, M; Fujisawa, T; Gratacós, E; Hadoke, PW; Miller, MR; Rennie, J; Wang, K; Wang, R, 2013) |
| "As hydrogen sulfide (H(2)S) has pro-angiogenic and anti-oxidative characteristics, we hypothesized that H(2)S levels could play a role in the pathogenesis of preeclampsia and studied the placental expression of the H(2)S-producing enzymes cystathionine-γ-lyase (CSE) and cystathionine-β-synthase (CBS)." | 5.38 | Hydrogen sulfide producing enzymes in pregnancy and preeclampsia. ( Bos, EM; Erwich, JJ; Faas, MM; Holwerda, KM; Lely, AT; Rajakumar, A; Ris-Stalpers, C; Timmer, A; van Goor, H; van Pampus, MG, 2012) |
| "The three known gasotransmitters, nitric oxide, carbon monoxide, and hydrogen sulfide are involved in key processes throughout pregnancy." | 5.05 | Maternal disease and gasotransmitters. ( Boeldt, DS; Mauro, AK; Rengarajan, A, 2020) |
| "The shift has been made to view preeclampsia as a systemic disease with widespread endothelial damage and the potential to affect future cardiovascular diseases rather than a self-limited occurrence." | 2.53 | Preeclampsia: Updates in Pathogenesis, Definitions, and Guidelines. ( Brima, W; Jim, B; Phipps, E; Prasanna, D, 2016) |
| " By having both direct effects on its receptor and increasing the bioavailability of vascular endothelial growth factor, H2S is proangiogenic." | 2.52 | Hydrogen sulfide: role in vascular physiology and pathology. ( Holwerda, KM; Karumanchi, SA; Lely, AT, 2015) |
| "Our laboratory demonstrated that preeclampsia is associated with high soluble fms-like tyrosine kinase 1 (sFlt-1) and low heme oxygenase-1 (HO1/Hmox1) expression." | 1.62 | MZe786, a hydrogen sulfide-releasing aspirin prevents preeclampsia in heme oxygenase-1 haplodeficient pregnancy under high soluble flt-1 environment. ( Agrawal, S; Ahmad, S; Ahmed, A; Alzahrani, FA; Dias, IH; Rezai, H; Sanchez-Aranguren, L; Sparatore, A; Wang, K, 2021) |
| "In newborns born to mothers with preeclampsia, an increase in the concentration of hydrogen sulfide was detected in the blood, which is probably a compensatory reaction aimed at restoring vascular homeostasis during early postnatal adaptation." | 1.62 | Hydrogen sulfide content in pregnant women with preeclampsia in late gestation and their newborns. ( Baev, TO; Kharlamova, NV; Klycheva, MM; Kuzmenko, GN; Nazarov, SB; Panova, IA; Popova, IG; Sadov, RI; Sitnikova, OG; Veselkova, YN, 2021) |
| "Suramin treatment exerted negligible effect on the RAS pathway in the adult male offspring kidneys." | 1.43 | N-Acetylcysteine Prevents Programmed Hypertension in Male Rat Offspring Born to Suramin-Treated Mothers. ( Hsu, CN; Lee, CT; Lin, YJ; Tain, YL; Tsai, CC, 2016) |
| "The exact etiology of preeclampsia is unknown, but there is growing evidence of an imbalance in angiogenic growth factors and abnormal placentation." | 1.39 | Dysregulation of hydrogen sulfide producing enzyme cystathionine γ-lyase contributes to maternal hypertension and placental abnormalities in preeclampsia. ( Ahmad, S; Ahmed, A; Baily, J; Buhimschi, CS; Buhimschi, IA; Cai, M; Crispi, F; Cudmore, M; Fujisawa, T; Gratacós, E; Hadoke, PW; Miller, MR; Rennie, J; Wang, K; Wang, R, 2013) |
| "As hydrogen sulfide (H(2)S) has pro-angiogenic and anti-oxidative characteristics, we hypothesized that H(2)S levels could play a role in the pathogenesis of preeclampsia and studied the placental expression of the H(2)S-producing enzymes cystathionine-γ-lyase (CSE) and cystathionine-β-synthase (CBS)." | 1.38 | Hydrogen sulfide producing enzymes in pregnancy and preeclampsia. ( Bos, EM; Erwich, JJ; Faas, MM; Holwerda, KM; Lely, AT; Rajakumar, A; Ris-Stalpers, C; Timmer, A; van Goor, H; van Pampus, MG, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 13 (72.22) | 24.3611 |
| 2020's | 5 (27.78) | 2.80 |
| Authors | Studies |
|---|---|
| Du, J | 1 |
| Wang, P | 1 |
| Gou, Q | 1 |
| Jin, S | 1 |
| Xue, H | 1 |
| Li, D | 1 |
| Tian, D | 1 |
| Sun, J | 1 |
| Zhang, X | 1 |
| Teng, X | 1 |
| Wu, Y | 1 |
| Rengarajan, A | 1 |
| Mauro, AK | 1 |
| Boeldt, DS | 1 |
| Rezai, H | 2 |
| Ahmad, S | 4 |
| Alzahrani, FA | 2 |
| Sanchez-Aranguren, L | 1 |
| Dias, IH | 1 |
| Agrawal, S | 1 |
| Sparatore, A | 2 |
| Wang, K | 4 |
| Ahmed, A | 5 |
| Saif, J | 1 |
| Litvinova, K | 1 |
| Popova, IG | 1 |
| Sitnikova, OG | 1 |
| Nazarov, SB | 1 |
| Sadov, RI | 1 |
| Panova, IA | 1 |
| Baev, TO | 1 |
| Kuzmenko, GN | 1 |
| Kharlamova, NV | 1 |
| Klycheva, MM | 1 |
| Veselkova, YN | 1 |
| Bos, M | 1 |
| Schoots, MH | 1 |
| Fernandez, BO | 1 |
| Mikus-Lelinska, M | 1 |
| Lau, LC | 1 |
| Eikmans, M | 1 |
| van Goor, H | 3 |
| Gordijn, SJ | 1 |
| Pasch, A | 1 |
| Feelisch, M | 1 |
| van der Hoorn, MP | 1 |
| Bir, SC | 1 |
| Kevil, CG | 1 |
| Cai, M | 2 |
| Rennie, J | 2 |
| Fujisawa, T | 2 |
| Crispi, F | 2 |
| Baily, J | 2 |
| Miller, MR | 2 |
| Cudmore, M | 2 |
| Hadoke, PW | 2 |
| Wang, R | 2 |
| Gratacós, E | 2 |
| Buhimschi, IA | 2 |
| Buhimschi, CS | 2 |
| Holwerda, KM | 3 |
| Faas, MM | 2 |
| Lely, AT | 3 |
| Tsikas, D | 1 |
| Cooper, AJ | 1 |
| Weissgerber, TL | 1 |
| Craici, IM | 1 |
| Wagner, SJ | 1 |
| Grande, JP | 1 |
| Garovic, VD | 1 |
| Ramma, W | 1 |
| Karumanchi, SA | 1 |
| Hu, T | 1 |
| Wang, G | 1 |
| Zhu, Z | 1 |
| Huang, Y | 1 |
| Gu, H | 1 |
| Ni, X | 1 |
| Phipps, E | 1 |
| Prasanna, D | 1 |
| Brima, W | 1 |
| Jim, B | 1 |
| Tain, YL | 1 |
| Hsu, CN | 1 |
| Lee, CT | 1 |
| Lin, YJ | 1 |
| Tsai, CC | 1 |
| Bos, EM | 1 |
| Rajakumar, A | 1 |
| Ris-Stalpers, C | 1 |
| van Pampus, MG | 1 |
| Timmer, A | 1 |
| Erwich, JJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pravastatin to Prevent Preeclampsia and Reduce Maternal-Neonatal Mortality and Morbidity in High Risk Preeclampsia Patients[NCT03648970] | Phase 2 | 280 participants (Anticipated) | Interventional | 2018-03-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for hydrogen sulfide and Edema-Proteinuria-Hypertension Gestosis
| Article | Year |
|---|---|
Maternal disease and gasotransmitters.
Topics: Animals; Carbon Monoxide; Female; Gasotransmitters; Humans; Hydrogen Sulfide; Nitric Oxide; Parturit | 2020 |
Gasotransmitters: a solution for the therapeutic dilemma in preeclampsia?
Topics: Carbon Monoxide; Female; Humans; Hydrogen Sulfide; Neurotransmitter Agents; Nitric Oxide; Placenta; | 2013 |
Advances in the pathophysiology of preeclampsia and related podocyte injury.
Topics: Animals; Disease Models, Animal; Female; Guidelines as Topic; Humans; Hydrogen Sulfide; Podocytes; P | 2014 |
Unravelling the theories of pre-eclampsia: are the protective pathways the new paradigm?
Topics: Animals; Carbon Monoxide; Drug Design; Female; Humans; Hydrogen Sulfide; Inflammation; Oxidative Str | 2015 |
Hydrogen sulfide: role in vascular physiology and pathology.
Topics: Animals; Female; Humans; Hydrogen Sulfide; Hypertension; Muscle, Smooth, Vascular; Myocytes, Smooth | 2015 |
Preeclampsia: Updates in Pathogenesis, Definitions, and Guidelines.
Topics: Autoantibodies; Endoglin; Female; Heme Oxygenase (Decyclizing); Humans; Hydrogen Sulfide; Nitric Oxi | 2016 |
12 other studies available for hydrogen sulfide and Edema-Proteinuria-Hypertension Gestosis
| Article | Year |
|---|---|
Hydrogen sulfide ameliorated preeclampsia via suppression of toll-like receptor 4-activated inflammation in the rostral ventrolateral medulla of rats.
Topics: Animals; Blood Pressure; Female; Humans; Hydrogen Sulfide; Inflammation; Medulla Oblongata; Pre-Ecla | 2022 |
MZe786, a hydrogen sulfide-releasing aspirin prevents preeclampsia in heme oxygenase-1 haplodeficient pregnancy under high soluble flt-1 environment.
Topics: Animals; Aspirin; Female; Heme Oxygenase-1; Hydrogen Sulfide; Membrane Proteins; Mice; Pre-Eclampsia | 2021 |
Hydrogen sulfide releasing molecule MZe786 inhibits soluble Flt-1 and prevents preeclampsia in a refined RUPP mouse model.
Topics: Animals; Disease Models, Animal; Female; Hydrogen Sulfide; Mice; Mice, Inbred C57BL; Perfusion; Plac | 2021 |
Hydrogen sulfide content in pregnant women with preeclampsia in late gestation and their newborns.
Topics: Female; Humans; Hydrogen Sulfide; Hypertension; Infant, Newborn; Mothers; Pre-Eclampsia; Pregnancy; | 2021 |
Reactive Species Interactome Alterations in Oocyte Donation Pregnancies in the Absence and Presence of Pre-Eclampsia.
Topics: Adult; Case-Control Studies; Female; Fertilization in Vitro; Humans; Hydrogen Sulfide; Maternal Age; | 2019 |
Sulfane sustains vascular health: insights into cystathionine γ-lyase function.
Topics: Animals; Atherosclerosis; Cystathionine gamma-Lyase; Female; Humans; Hydrogen Sulfide; Hypertension; | 2013 |
Dysregulation of hydrogen sulfide producing enzyme cystathionine γ-lyase contributes to maternal hypertension and placental abnormalities in preeclampsia.
Topics: Adolescent; Adult; Alkynes; Animals; Antigens, CD; Cells, Cultured; Cystathionine gamma-Lyase; Disea | 2013 |
Letter by Tsikas and Cooper regarding article, "dysregulation of hydrogen sulfide (H2S) producing enzyme cystathionine γ-lyase (CSE) contributes to maternal hypertension and placental abnormalities in preeclampsia".
Topics: Animals; Cystathionine gamma-Lyase; Female; Humans; Hydrogen Sulfide; Hypertension; Placenta Disease | 2014 |
Response to letter regarding article, "dysregulation of hydrogen sulfide (H2S) producing enzyme cystathionine γ-lyase (CSE) contributes to maternal hypertension and placental abnormalities in preeclampsia".
Topics: Animals; Cystathionine gamma-Lyase; Female; Humans; Hydrogen Sulfide; Hypertension; Placenta Disease | 2014 |
Increased ADAM10 expression in preeclamptic placentas is associated with decreased expression of hydrogen sulfide production enzymes.
Topics: ADAM Proteins; ADAM10 Protein; Amyloid Precursor Protein Secretases; Cystathionine beta-Synthase; Cy | 2015 |
N-Acetylcysteine Prevents Programmed Hypertension in Male Rat Offspring Born to Suramin-Treated Mothers.
Topics: Acetylcysteine; Animals; Arginine; Blood Pressure; Female; Fetal Development; Hydrogen Sulfide; Hype | 2016 |
Hydrogen sulfide producing enzymes in pregnancy and preeclampsia.
Topics: Adult; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Down-Regulation; Female; Humans; Hydr | 2012 |