hydrogen sulfide has been researched along with Down Syndrome in 10 studies
Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
Excerpt | Relevance | Reference |
---|---|---|
"Mental retardation is progressive in Down syndrome: individuals are born with normal intelligence which starts to decline linearly within the first year." | 5.31 | Mental retardation in Down syndrome: a hydrogen sulfide hpothesis. ( Kamoun, P, 2001) |
" Chronic administration of CSE inhibitor induces arterial hypertension in the rat." | 2.42 | [Hydrogen sulfide as a biologically active mediator in the cardiovascular system]. ( Bełtowski, J, 2004) |
"Prenatal treatment of Down syndrome fetuses is also suggested." | 1.51 | Mental retardation in Down syndrome: Two ways to treat. ( Kamoun, PP, 2019) |
"Mental retardation is progressive in Down syndrome: individuals are born with normal intelligence which starts to decline linearly within the first year." | 1.31 | Mental retardation in Down syndrome: a hydrogen sulfide hpothesis. ( Kamoun, P, 2001) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 5 (50.00) | 29.6817 |
2010's | 2 (20.00) | 24.3611 |
2020's | 3 (30.00) | 2.80 |
Authors | Studies |
---|---|
Kamoun, PP | 1 |
Panagaki, T | 2 |
Randi, EB | 2 |
Augsburger, F | 2 |
Szabo, C | 4 |
Zuhra, K | 1 |
Majtan, T | 1 |
Kamoun, P | 4 |
Belardinelli, MC | 2 |
Chabli, A | 2 |
Lallouchi, K | 1 |
Chadefaux-Vekemans, B | 2 |
Bełtowski, J | 1 |
4 reviews available for hydrogen sulfide and Down Syndrome
Article | Year |
---|---|
The re-emerging pathophysiological role of the cystathionine-β-synthase - hydrogen sulfide system in Down syndrome.
Topics: Animals; Cystathionine beta-Synthase; Down Syndrome; Energy Metabolism; Humans; Hydrogen Sulfide; Ox | 2020 |
Cystathionine-β-Synthase: Molecular Regulation and Pharmacological Inhibition.
Topics: Animals; Cystathionine beta-Synthase; Down Syndrome; Enzyme Inhibitors; Humans; Hydrogen Sulfide; Ne | 2020 |
Endogenous production of hydrogen sulfide in mammals.
Topics: Alzheimer Disease; Animals; Down Syndrome; Enzymes; Humans; Hydrogen Sulfide | 2004 |
[Hydrogen sulfide as a biologically active mediator in the cardiovascular system].
Topics: Alzheimer Disease; Animals; Brain; Cardiovascular System; Cyclic AMP; Cystathionine beta-Synthase; D | 2004 |
6 other studies available for hydrogen sulfide and Down Syndrome
Article | Year |
---|---|
Mental retardation in Down syndrome: Two ways to treat.
Topics: Aminooxyacetic Acid; Animals; Benserazide; Brain; Chromosomes, Human, Pair 21; Cobamides; Cystathion | 2019 |
Overproduction of H
Topics: Aminooxyacetic Acid; Cell Proliferation; Cells, Cultured; Cystathionine beta-Synthase; Down Syndrome | 2019 |
Role of 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation and Cellular Bioenergetics in Human Down Syndrome Fibroblasts.
Topics: Cell Proliferation; Child; Child, Preschool; Cysteine; Down Syndrome; Energy Metabolism; Female; Fib | 2020 |
Endogenous hydrogen sulfide overproduction in Down syndrome.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Down Syndrome; Female; Humans; Hydrogen Sulfide; I | 2003 |
Urinary sulfur compounds in Down syndrome.
Topics: Adult; Cystine; Down Syndrome; Female; Humans; Hydrogen Sulfide; Male; Sulfur Compounds; Taurine; Th | 2001 |
Mental retardation in Down syndrome: a hydrogen sulfide hpothesis.
Topics: Down Syndrome; Humans; Hydrogen Sulfide; Infant; Infant, Newborn; Intellectual Disability; Intellige | 2001 |