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hydrogen sulfide and Diabetic Cardiomyopathies

hydrogen sulfide has been researched along with Diabetic Cardiomyopathies in 18 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Diabetic Cardiomyopathies: Diabetes complications in which VENTRICULAR REMODELING in the absence of CORONARY ATHEROSCLEROSIS and hypertension results in cardiac dysfunctions, typically LEFT VENTRICULAR DYSFUNCTION. The changes also result in myocardial hypertrophy, myocardial necrosis and fibrosis, and collagen deposition due to impaired glucose tolerance.

Research Excerpts

ExcerptRelevanceReference
"The aim of the present study was to determine the role of hydrogen sulfide (H2S) in improving myocardial fibrosis and its effects on oxidative stress, endoplasmic reticulum (ER) stress and cell apoptosis in diabetic rats, by regulating the Janus kinase̸signal transducer and activator of transcription (JAK̸STAT) signaling pathway."7.88Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway. ( Chu, C; Jiang, Z; Li, Y; Li, Z; Liang, B; Liu, M; Yang, J, 2018)
"In order to explore the effects of hydrogen sulfide (H2S) on myocardial fibrosis in diabetic rats and its underlying mechanisms, intraperitoneal injections of streptozotocin were used to establish the diabetes models and sodium hydrosulfide (NaHS) was used as an exogenous donor of H2S."7.81Effects of hydrogen sulfide on myocardial fibrosis in diabetic rats: Changes in matrix metalloproteinases parameters. ( Li, F; Luo, J; Wu, Z; Xiao, T; Yang, J; Zeng, O, 2015)
"The aim of the present study was to determine the role of hydrogen sulfide (H2S) in improving myocardial fibrosis and its effects on oxidative stress, endoplasmic reticulum (ER) stress and cell apoptosis in diabetic rats, by regulating the Janus kinase̸signal transducer and activator of transcription (JAK̸STAT) signaling pathway."3.88Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway. ( Chu, C; Jiang, Z; Li, Y; Li, Z; Liang, B; Liu, M; Yang, J, 2018)
"Previous studies have suggested that exogenous hydrogen sulfide can alleviate the development of diabetic cardiomyopathy (DCM) by inhibiting oxidative stress, inflammation, and apoptosis."3.88Exogenous hydrogen sulfide attenuates the development of diabetic cardiomyopathy via the FoxO1 pathway. ( Chao, YL; Chen, SL; Gu, Y; Kong, XQ; Luo, J; Ren, XM; Ye, P; Zhang, DM; Zhu, YR; Zuo, GF, 2018)
"In order to explore the effects of hydrogen sulfide (H2S) on myocardial fibrosis in diabetic rats and its underlying mechanisms, intraperitoneal injections of streptozotocin were used to establish the diabetes models and sodium hydrosulfide (NaHS) was used as an exogenous donor of H2S."3.81Effects of hydrogen sulfide on myocardial fibrosis in diabetic rats: Changes in matrix metalloproteinases parameters. ( Li, F; Luo, J; Wu, Z; Xiao, T; Yang, J; Zeng, O, 2015)
"Hydrogen sulfide (H2S) has been found to be the third gaseous signaling molecule with anti‑ER stress effects."1.43Hydrogen sulfide exhibits cardioprotective effects by decreasing endoplasmic reticulum stress in a diabetic cardiomyopathy rat model. ( Li, F; Li, L; Li, Y; Luo, J; Wu, Z; Xiao, T; Yang, J; Zeng, O, 2016)
"Hydrogen sulfide (H2S) is an endogenously produced signaling molecule that is critical for the regulation of cardiovascular homeostasis."1.42Hydrogen sulfide attenuates high fat diet-induced cardiac dysfunction via the suppression of endoplasmic reticulum stress. ( Barr, LA; Calvert, JW; Lambert, JP; Nicholson, CK; Shimizu, Y, 2015)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's12 (66.67)24.3611
2020's6 (33.33)2.80

Authors

AuthorsStudies
Deng, NH1
Luo, W1
Gui, DD1
Yan, BJ1
Zhou, K1
Tian, KJ1
Ren, Z1
Xiong, WH1
Jiang, ZS1
Carbone, F1
Montecucco, F1
Zhao, H1
Liu, H2
Yang, Y1
Lan, T1
Wang, H2
Wu, D1
Dugbartey, GJ1
Wonje, QL1
Alornyo, KK1
Adams, I1
Diaba, DE1
Liu, X1
Yang, R2
Bai, W1
Xu, X1
Bi, F1
Hao, Y1
Yang, Q1
Li, H1
Lv, S1
Liu, M1
Li, Y2
Liang, B1
Li, Z1
Jiang, Z1
Chu, C1
Yang, J3
Ye, P1
Gu, Y1
Zhu, YR1
Chao, YL1
Kong, XQ1
Luo, J3
Ren, XM1
Zuo, GF1
Zhang, DM1
Chen, SL1
Kar, S1
Kambis, TN1
Mishra, PK1
Patel, VB1
McLean, BA1
Chen, X1
Oudit, GY1
Zhou, X1
An, G1
Lu, X1
Barr, LA1
Shimizu, Y1
Lambert, JP1
Nicholson, CK1
Calvert, JW1
Yang, H1
Mao, Y1
Tan, B1
Luo, S1
Zhu, Y1
Xiao, T2
Zeng, O2
Wu, Z2
Li, F2
Cheng, YS1
Dai, DZ1
Dai, Y1
Zhu, DD1
Liu, BC1
Li, L1
Jia, Q1
Liu, XF1
Gao, Q1
Wang, L1
Ma, SF1
Yang, F1
Yu, X1
Li, T1
Wu, J2
Zhao, Y1
Liu, J1
Sun, A1
Dong, S1
Zhong, X1
Xu, C1
Lu, F1
Zhang, W1

Reviews

4 reviews available for hydrogen sulfide and Diabetic Cardiomyopathies

ArticleYear
Hydrogen sulfide plays a potential alternative for the treatment of metabolic disorders of diabetic cardiomyopathy.
    Molecular and cellular biochemistry, 2022, Volume: 477, Issue:1

    Topics: Animals; Diabetic Cardiomyopathies; Energy Metabolism; Humans; Hydrogen Sulfide; Insulin Resistance;

2022
Hydrogen Sulfide Plays an Important Role by Regulating Endoplasmic Reticulum Stress in Diabetes-Related Diseases.
    International journal of molecular sciences, 2022, Jun-28, Volume: 23, Issue:13

    Topics: Diabetes Mellitus; Diabetic Cardiomyopathies; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; H

2022
Exogenous Hydrogen Sulfide Plays an Important Role by Regulating Autophagy in Diabetic-Related Diseases.
    International journal of molecular sciences, 2021, Jun-23, Volume: 22, Issue:13

    Topics: Animals; Autophagy; Depressive Disorder; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Cardiomy

2021
Hydrogen sulfide-mediated regulation of cell death signaling ameliorates adverse cardiac remodeling and diabetic cardiomyopathy.
    American journal of physiology. Heart and circulatory physiology, 2019, 06-01, Volume: 316, Issue:6

    Topics: Animals; Apoptosis; Autophagy; Cardiovascular Agents; Diabetic Cardiomyopathies; Humans; Hydrogen Su

2019

Other Studies

14 other studies available for hydrogen sulfide and Diabetic Cardiomyopathies

ArticleYear
Hydrogen sulphide: Diabetic cardiomyopathy as the paradigm of its pleiotropic function.
    European journal of clinical investigation, 2022, Volume: 52, Issue:9

    Topics: Diabetes Mellitus; Diabetic Cardiomyopathies; Humans; Hydrogen Sulfide

2022
Alpha-lipoic acid treatment improves adverse cardiac remodelling in the diabetic heart - The role of cardiac hydrogen sulfide-synthesizing enzymes.
    Biochemical pharmacology, 2022, Volume: 203

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Hydr

2022
Involvement of amylin B-H2S-connexin 43 signaling pathway in vascular dysfunction and enhanced ischemia-reperfusion-induced myocardial injury in diabetic rats.
    Bioscience reports, 2020, 06-26, Volume: 40, Issue:6

    Topics: Amylin Receptor Agonists; Animals; Carbenoxolone; Connexin 43; Diabetic Angiopathies; Diabetic Cardi

2020
Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway.
    International journal of molecular medicine, 2018, Volume: 41, Issue:4

    Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Endoplasmic Reticulu

2018
Exogenous hydrogen sulfide attenuates the development of diabetic cardiomyopathy via the FoxO1 pathway.
    Journal of cellular physiology, 2018, Volume: 233, Issue:12

    Topics: Animals; Apoptosis; Diabetic Cardiomyopathies; Disease Models, Animal; Forkhead Box Protein O1; Hear

2018
Hydrogen sulfide: an old gas with new cardioprotective effects.
    Clinical science (London, England : 1979), 2015, Volume: 128, Issue:5

    Topics: Animals; Diabetic Cardiomyopathies; Hydrogen Sulfide; Male

2015
Hydrogen sulfide attenuates the development of diabetic cardiomyopathy.
    Clinical science (London, England : 1979), 2015, Volume: 128, Issue:5

    Topics: Animals; Cytokines; Diabetic Cardiomyopathies; Hydrogen Sulfide; Inflammation Mediators; Male; Oxida

2015
Hydrogen sulfide attenuates high fat diet-induced cardiac dysfunction via the suppression of endoplasmic reticulum stress.
    Nitric oxide : biology and chemistry, 2015, Apr-30, Volume: 46

    Topics: Adiponectin; Administration, Oral; AMP-Activated Protein Kinases; Animals; Diabetic Cardiomyopathies

2015
The protective effects of endogenous hydrogen sulfide modulator, S-propargyl-cysteine, on high glucose-induced apoptosis in cardiomyocytes: A novel mechanism mediated by the activation of Nrf2.
    European journal of pharmacology, 2015, Aug-15, Volume: 761

    Topics: Animals; Antioxidants; Apoptosis; Blood Glucose; Cell Line; Cystathionine gamma-Lyase; Cysteine; Cyt

2015
Effects of hydrogen sulfide on myocardial fibrosis in diabetic rats: Changes in matrix metalloproteinases parameters.
    Bio-medical materials and engineering, 2015, Volume: 26 Suppl 1

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Fibrosis; Heart; Hydrogen Sulfi

2015
Exogenous hydrogen sulphide ameliorates diabetic cardiomyopathy in rats by reversing disordered calcium-handling system in sarcoplasmic reticulum.
    The Journal of pharmacy and pharmacology, 2016, Volume: 68, Issue:3

    Topics: Animals; Calcium; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Disease Models, Animal

2016
Hydrogen sulfide exhibits cardioprotective effects by decreasing endoplasmic reticulum stress in a diabetic cardiomyopathy rat model.
    Molecular medicine reports, 2016, Volume: 14, Issue:1

    Topics: Animals; Blood Glucose; Body Weight; Cardiotonic Agents; Diabetic Cardiomyopathies; Disease Models,

2016
[Effect of hydrogen sulfide on oxidative stress and endoplasmic reticulum stress in diabetic cardiomyopathy].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2016, Volume: 32, Issue:1

    Topics: Animals; Apoptosis; Caspase 12; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Endoplas

2016
Exogenous H
    American journal of physiology. Endocrinology and metabolism, 2017, 03-01, Volume: 312, Issue:3

    Topics: Animals; Apoptosis; Blood Glucose; Blotting, Western; Cytochromes c; Diabetes Mellitus, Experimental

2017