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hydrogen sulfide and Degenerative Diseases, Central Nervous System

hydrogen sulfide has been researched along with Degenerative Diseases, Central Nervous System in 26 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Research Excerpts

ExcerptRelevanceReference
"Accumulating evidence suggests that abnormal levels of homocysteine are associated with vascular dysfunctions, cancer cell proliferation and various neurodegenerative diseases."7.83Sulfheme formation during homocysteine S-oxygenation by catalase in cancers and neurodegenerative diseases. ( Andriamihaja, M; Artaud, I; Blachier, F; Castillo, FT; Galardon, E; Hessani, A; Lan, A; Liot, G; Padovani, D; Pilati, C; Sen, S, 2016)
"The manner in which hydrogen sulfide (H2S) suppresses neuroinflammation is poorly understood."7.80CaMKKβ-dependent activation of AMP-activated protein kinase is critical to suppressive effects of hydrogen sulfide on neuroinflammation. ( Alkayed, NJ; Ao, G; Cao, Y; Cheng, J; Hu, L; Jia, J; Jin, M; Liu, H; Wang, X; Wu, J; Zhen, X; Zheng, S; Zhou, X, 2014)
"Glaucoma is a neurodegenerative disease of visual system characterized by gradual loss of retinal ganglion cells (RGC)."5.72Hydrogen sulfide supplement preserves mitochondrial function of retinal ganglion cell in a rat glaucoma model. ( Chen, J; Huang, P; Huang, S; Liu, X; Shen, X; Wang, J; Yu, H; Zhong, Y, 2022)
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"Studies have shown that hydrogen sulfide (H2S) exerts a neuroprotective effect and may have a therapeutic value for treating neurodegenerative diseases including Parkinson's disease."3.88Involvement of adenosine triphosphate-sensitive potassium channels in the neuroprotective activity of hydrogen sulfide in the 6-hydroxydopamine-induced animal model of Parkinson's disease. ( Babayan-Tazehkand, A; Haghdoost-Yazdi, H; Rastgoo, N; Sarbazi-Golezari, A; Sarookhani, MR, 2018)
"Accumulating evidence suggests that abnormal levels of homocysteine are associated with vascular dysfunctions, cancer cell proliferation and various neurodegenerative diseases."3.83Sulfheme formation during homocysteine S-oxygenation by catalase in cancers and neurodegenerative diseases. ( Andriamihaja, M; Artaud, I; Blachier, F; Castillo, FT; Galardon, E; Hessani, A; Lan, A; Liot, G; Padovani, D; Pilati, C; Sen, S, 2016)
"The manner in which hydrogen sulfide (H2S) suppresses neuroinflammation is poorly understood."3.80CaMKKβ-dependent activation of AMP-activated protein kinase is critical to suppressive effects of hydrogen sulfide on neuroinflammation. ( Alkayed, NJ; Ao, G; Cao, Y; Cheng, J; Hu, L; Jia, J; Jin, M; Liu, H; Wang, X; Wu, J; Zhen, X; Zheng, S; Zhou, X, 2014)
"Hydrogen sulfide is a gaseous signaling molecule or gasotransmitter which plays important roles in a wide spectrum of physiologic processes in the brain and peripheral tissues."2.58Gasotransmitter hydrogen sulfide signaling in neuronal health and disease. ( Paul, BD; Snyder, SH, 2018)
"Hydrogen sulfide (H2S)has emerged as pivotal signaling molecules since it is recognized as the third gasotransmitter together with nitric oxide and carbon monoxide."2.55[The Molecular Switches and Atomic Biological Mechanisms Underlying the Physiological and Pathophysio-logical Effects of Hydrogen Sulfide to Regulate Its "Receptors"]. ( Cai, WJ; Li, XH; Tao, BB; Wang, MJ; Xue, WL; Zhu, YC, 2017)
"Formaldehyde (FA) has neurotoxic characteristics and causes neurodegenerative disease."1.91Hydrogen sulfide antagonizes formaldehyde-induced ferroptosis via preventing ferritinophagy by upregulation of GDF11 in HT22 cells. ( Huang, HL; Tang, XQ; Tang, YH; Tang, YY; Wu, L; Zhang, PP; Zou, W, 2023)
"Glaucoma is a neurodegenerative disease of visual system characterized by gradual loss of retinal ganglion cells (RGC)."1.72Hydrogen sulfide supplement preserves mitochondrial function of retinal ganglion cell in a rat glaucoma model. ( Chen, J; Huang, P; Huang, S; Liu, X; Shen, X; Wang, J; Yu, H; Zhong, Y, 2022)
"Hydrogen sulfide also plays an important role in promoting resolution of inflammation, and restoration of normal tissue function."1.42Anti-inflammatory and cytoprotective properties of hydrogen sulfide. ( Gemici, B; Wallace, JL, 2015)
"Hydrogen sulfide (H(2)S) has been shown to protect neurons."1.37Inhaled hydrogen sulfide prevents neurodegeneration and movement disorder in a mouse model of Parkinson's disease. ( Ichinose, F; Kakinohana, M; Kaneki, M; Kida, K; Marutani, E; Tokuda, K; Yamada, M, 2011)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's14 (53.85)24.3611
2020's12 (46.15)2.80

Authors

AuthorsStudies
Paul, BD2
Huang, S1
Huang, P1
Yu, H2
Chen, J1
Liu, X1
Wang, J3
Shen, X1
Zhong, Y1
Ma, B1
Mao, Y1
Chang, L1
Dai, T1
Xin, X1
Ma, F1
Wang, Z1
Shen, Z1
Mei, Q1
Zhu, Y1
Nie, S1
Jing, Z1
Deng, Y1
Zhang, Y1
Ye, Z1
Ge, Y1
Rodkin, S2
Nwosu, C2
Sannikov, A2
Tyurin, A1
Chulkov, VS1
Raevskaya, M2
Ermakov, A1
Kirichenko, E1
Gasanov, M2
Tang, YH1
Wu, L1
Huang, HL1
Zhang, PP1
Zou, W2
Tang, XQ2
Tang, YY2
Wu, K1
Wang, X4
Gong, L1
Zhai, X1
Wang, K1
Qiu, X1
Zhang, H1
Tang, Z1
Jiang, H1
Spalloni, A1
de Stefano, S1
Gimenez, J1
Greco, V1
Mercuri, NB1
Chiurchiù, V1
Longone, P1
Tushev, A1
Vasilieva, I1
Dogaru, BG1
Munteanu, C1
Zhuge, W1
Zhuge, Q1
Wang, W1
Lu, X1
You, R1
Liu, L1
Ye, Y1
Ding, S1
Snyder, SH1
Sarookhani, MR1
Haghdoost-Yazdi, H1
Sarbazi-Golezari, A1
Babayan-Tazehkand, A1
Rastgoo, N1
Xue, WL1
Cai, WJ1
Tao, BB1
Wang, MJ1
Li, XH1
Zhu, YC1
Mikami, Y1
Zhu, WW1
Ning, M1
Peng, YZ1
Kang, X1
Zhan, KB1
Zhang, P1
Zhou, X1
Cao, Y1
Ao, G1
Hu, L1
Liu, H1
Wu, J1
Jin, M1
Zheng, S1
Zhen, X1
Alkayed, NJ1
Jia, J1
Cheng, J1
Peers, C1
Boyle, JP1
Gemici, B1
Wallace, JL1
Nagpure, BV1
Bian, JS1
Padovani, D1
Hessani, A1
Castillo, FT1
Liot, G1
Andriamihaja, M1
Lan, A1
Pilati, C1
Blachier, F1
Sen, S1
Galardon, E1
Artaud, I1
Sen, N1
Wang, R1
Kida, K1
Yamada, M1
Tokuda, K1
Marutani, E1
Kakinohana, M1
Kaneki, M1
Ichinose, F1
Gong, QH1
Shi, XR1
Hong, ZY1
Pan, LL1
Liu, XH1
Zhu, YZ1

Reviews

13 reviews available for hydrogen sulfide and Degenerative Diseases, Central Nervous System

ArticleYear
Cysteine metabolism and hydrogen sulfide signaling in Huntington's disease.
    Free radical biology & medicine, 2022, Volume: 186

    Topics: Cystathionine gamma-Lyase; Cysteine; Humans; Huntington Disease; Hydrogen Sulfide; Neurodegenerative

2022
The Role of Gasotransmitter-Dependent Signaling Mechanisms in Apoptotic Cell Death in Cardiovascular, Rheumatic, Kidney, and Neurodegenerative Diseases and Mental Disorders.
    International journal of molecular sciences, 2023, Mar-23, Volume: 24, Issue:7

    Topics: Apoptosis; Carbon Monoxide; Gasotransmitters; Humans; Hydrogen Sulfide; Kidney; Mental Disorders; Ne

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
The Ying and Yang of Hydrogen Sulfide as a Paracrine/Autocrine Agent in Neurodegeneration: Focus on Amyotrophic Lateral Sclerosis.
    Cells, 2023, Jun-22, Volume: 12, Issue:13

    Topics: Amyotrophic Lateral Sclerosis; Central Nervous System; Humans; Hydrogen Sulfide; Neurodegenerative D

2023
The Role of Hydrogen Sulfide in Regulation of Cell Death following Neurotrauma and Related Neurodegenerative and Psychiatric Diseases.
    International journal of molecular sciences, 2023, Jun-28, Volume: 24, Issue:13

    Topics: Alzheimer Disease; Animals; Apoptosis; Hydrogen Sulfide; Neurodegenerative Diseases; Quality of Life

2023
The Role of Hydrogen Sulfide (H
    International journal of molecular sciences, 2023, Aug-08, Volume: 24, Issue:16

    Topics: Cell Survival; Epigenesis, Genetic; Humans; Huntington Disease; Hydrogen Sulfide; Neurodegenerative

2023
Gasotransmitter hydrogen sulfide signaling in neuronal health and disease.
    Biochemical pharmacology, 2018, Volume: 149

    Topics: Animals; Central Nervous System; Gasotransmitters; Humans; Hydrogen Sulfide; Neurodegenerative Disea

2018
[The Molecular Switches and Atomic Biological Mechanisms Underlying the Physiological and Pathophysio-logical Effects of Hydrogen Sulfide to Regulate Its "Receptors"].
    Sheng li ke xue jin zhan [Progress in physiology], 2017, Volume: 48, Issue:1

    Topics: Asthma; Atherosclerosis; Carbon Monoxide; Cardiovascular System; Humans; Hydrogen Sulfide; Hypertens

2017
[Pathophysiological functions of gas mediators in neurodegeneration].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2018, Volume: 152, Issue:5

    Topics: Animals; Calcium; Calcium Signaling; Cells, Cultured; Gasotransmitters; Hydrogen Sulfide; Mice; Neur

2018
Oxidative modulation of K+ channels in the central nervous system in neurodegenerative diseases and aging.
    Antioxidants & redox signaling, 2015, Feb-20, Volume: 22, Issue:6

    Topics: Aging; Animals; Apoptosis; Carbon Monoxide; Central Nervous System; Gasotransmitters; Humans; Hydrog

2015
Brain, Learning, and Memory: Role of H2S in Neurodegenerative Diseases.
    Handbook of experimental pharmacology, 2015, Volume: 230

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Brain; Calcium; Humans; Hydrogen Sulfide; Learning;

2015
Functional and Molecular Insights of Hydrogen Sulfide Signaling and Protein Sulfhydration.
    Journal of molecular biology, 2017, 02-17, Volume: 429, Issue:4

    Topics: Animals; Brain Injuries, Traumatic; Cell Cycle; Cell Differentiation; Cell Proliferation; Fibrosis;

2017
A new hope for neurodegeneration: possible role of hydrogen sulfide.
    Journal of Alzheimer's disease : JAD, 2011, Volume: 24 Suppl 2

    Topics: Animals; Antioxidants; Humans; Hydrogen Sulfide; Models, Biological; Neurodegenerative Diseases

2011

Trials

1 trial available for hydrogen sulfide and Degenerative Diseases, Central Nervous System

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Other Studies

13 other studies available for hydrogen sulfide and Degenerative Diseases, Central Nervous System

ArticleYear
Hydrogen sulfide supplement preserves mitochondrial function of retinal ganglion cell in a rat glaucoma model.
    Cell and tissue research, 2022, Volume: 389, Issue:2

    Topics: Animals; Cytochromes c; Disease Models, Animal; Glaucoma; Hydrogen Sulfide; Mitochondria; Neurodegen

2022
    Pharmaceutical biology, 2022, Volume: 60, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury, Chronic; Concanavalin A; Cysteine; Cytokines; Hydro

2022
The link between increased Desulfovibrio and disease severity in Parkinson's disease.
    Applied microbiology and biotechnology, 2023, Volume: 107, Issue:9

    Topics: Desulfovibrio; Humans; Hydrogen Sulfide; Neurodegenerative Diseases; Parkinson Disease; Patient Acui

2023
Hydrogen sulfide antagonizes formaldehyde-induced ferroptosis via preventing ferritinophagy by upregulation of GDF11 in HT22 cells.
    Toxicology, 2023, 06-01, Volume: 491

    Topics: Animals; Bone Morphogenetic Proteins; Ferroptosis; Formaldehyde; Growth Differentiation Factors; Hyd

2023
Screening of H
    Biosensors & bioelectronics, 2023, Oct-01, Volume: 237

    Topics: Biosensing Techniques; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Sulfide; Mitochondria; Neurode

2023
Hydrogen sulphide ameliorates dopamine-induced astrocytic inflammation and neurodegeneration in minimal hepatic encephalopathy.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:23

    Topics: Animals; Apoptosis; Astrocytes; bcl-Associated Death Protein; bcl-X Protein; Behavior, Animal; Bioma

2020
Involvement of adenosine triphosphate-sensitive potassium channels in the neuroprotective activity of hydrogen sulfide in the 6-hydroxydopamine-induced animal model of Parkinson's disease.
    Behavioural pharmacology, 2018, Volume: 29, Issue:4

    Topics: Adenosine Triphosphate; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dop

2018
Hydrogen Sulfide Inhibits Formaldehyde-Induced Senescence in HT-22 Cells via Upregulation of Leptin Signaling.
    Neuromolecular medicine, 2019, Volume: 21, Issue:2

    Topics: Animals; Apoptosis; Cell Division; Cell Line; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor

2019
CaMKKβ-dependent activation of AMP-activated protein kinase is critical to suppressive effects of hydrogen sulfide on neuroinflammation.
    Antioxidants & redox signaling, 2014, Oct-20, Volume: 21, Issue:12

    Topics: AMP-Activated Protein Kinases; Animals; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cells, C

2014
Anti-inflammatory and cytoprotective properties of hydrogen sulfide.
    Methods in enzymology, 2015, Volume: 555

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cystathionine beta-Syntha

2015
Sulfheme formation during homocysteine S-oxygenation by catalase in cancers and neurodegenerative diseases.
    Nature communications, 2016, 11-16, Volume: 7

    Topics: Animals; Catalase; Cell Line, Tumor; Chromatography, High Pressure Liquid; Enzyme Activation; Heme;

2016
Hydrogen sulfide: the third gasotransmitter in biology and medicine.
    Antioxidants & redox signaling, 2010, May-01, Volume: 12, Issue:9

    Topics: Animals; Antioxidants; Humans; Hydrogen Sulfide; Hypoxia; Inflammation; Ischemia; Neurodegenerative

2010
Inhaled hydrogen sulfide prevents neurodegeneration and movement disorder in a mouse model of Parkinson's disease.
    Antioxidants & redox signaling, 2011, Jul-15, Volume: 15, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Administration, Inhalation; Animals; Apoptosis; Base S

2011