Page last updated: 2024-10-17

hydrogen sulfide and Colorectal Neoplasms

hydrogen sulfide has been researched along with Colorectal Neoplasms in 22 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.

Research Excerpts

ExcerptRelevanceReference
"Colorectal cancer is a common malignancy occurring in the digestive system and ranks second in cancer mortality worldwide."5.62Zinc oxide nanosphere for hydrogen sulfide scavenging and ferroptosis of colorectal cancer. ( Ding, K; Du, Z; He, J; Lu, W; Pan, X; Qi, Y; Yao, S; Zhou, M, 2021)
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
" Specifically, we assess hydrogen sulfide production in colorectal cancer based on stool, mucosa, and tissue samples collected on and off the tumor site within the same individuals."3.88Synthesis of multi-omic data and community metabolic models reveals insights into the role of hydrogen sulfide in colon cancer. ( Boardman, L; Cheek, EH; Chia, N; Davidson, J; Diener, C; Dutta, T; Gransee, J; Greene, M; Hale, VL; Jeraldo, P; Keeney, G; Larson, D; Lehman, J; Lyke, K; Martinez, C; Mundy, M; Nelson, H; Petterson, XM; Pettry, C; Reed, E; Resendis-Antonio, O; Scott, N; White, BA; Yao, J, 2018)
"In colorectal and ovarian cancers, an increase in the intratumor production of hydrogen sulfide (H2S) from cystathionine β-synthase (CBS) plays an important role in promoting the cellular bioenergetics, proliferation, and migration of cancer cells."2.52The therapeutic potential of cystathionine β-synthetase/hydrogen sulfide inhibition in cancer. ( Chao, C; Coletta, C; Hellmich, MR; Szabo, C, 2015)
"Colorectal cancer is a common malignancy occurring in the digestive system and ranks second in cancer mortality worldwide."1.62Zinc oxide nanosphere for hydrogen sulfide scavenging and ferroptosis of colorectal cancer. ( Ding, K; Du, Z; He, J; Lu, W; Pan, X; Qi, Y; Yao, S; Zhou, M, 2021)
"Links between colorectal cancer (CRC) and the gut microbiome have been established, but the specific microbial species and their role in carcinogenesis remain an active area of inquiry."1.48Distinct microbes, metabolites, and ecologies define the microbiome in deficient and proficient mismatch repair colorectal cancers. ( Blekhman, R; Boardman, L; Chen, J; Chia, N; Diener, C; Dutta, T; French, AJ; Gransee, J; Hale, VL; Jeraldo, P; Keeney, G; Larson, D; Lyke, K; Mundy, M; Nelson, H; Petterson, XM; Priya, S; Resendis-Antonio, O; Ridlon, J; Sung, J; Thibodeau, SN; White, BA; Yao, J, 2018)
"To determine colorectal and overall cancer incidence as part of a three-pronged investigation in response to the concerns of a First Nations community in Alberta, Canada, located close to sulfur-rich natural gas installations, and to determine whether the incidence of cancers observed in this reserve was higher than expected."1.36An investigation of cancer incidence in a First Nations community in Alberta, Canada, 1995-2006. ( Ashbury, F; Chen, Y; Colquhoun, A; Drobina, W; Jiang, Z; Maiangowi, G; McLeod, L; Panaro, L; Sihota, S; Tustin, J; Yacoub, W, 2010)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's12 (54.55)24.3611
2020's10 (45.45)2.80

Authors

AuthorsStudies
Pan, X1
Qi, Y1
Du, Z1
He, J2
Yao, S1
Lu, W1
Ding, K1
Zhou, M1
Kajsik, M1
Chovancova, B1
Liskova, V1
Babula, P1
Krizanova, O1
Lin, H1
Yu, Y1
Zhu, L1
Lai, N1
Zhang, L1
Guo, Y1
Lin, X1
Yang, D1
Ren, N1
Zhu, Z1
Dong, Q1
Duizer, C1
de Zoete, MR1
Hanna, DA1
Vitvitsky, V1
Banerjee, R1
Wu, L1
Ishigaki, Y1
Hu, Y1
Sugimoto, K1
Zeng, W1
Harimoto, T1
Sun, Y1
Suzuki, T1
Jiang, X1
Chen, HY1
Ye, D1
Yan, C1
Liu, D1
An, L1
Wang, Y1
Tian, Q1
Lin, J1
Yang, S1
Liu, H1
Xu, G2
Zhu, T2
Wang, R2
Tan, J1
Zhao, C2
Gu, X1
Housein, Z1
Kareem, TS1
Salihi, A1
Chen, S1
Wang, P1
Liu, Y1
Hale, VL2
Jeraldo, P2
Mundy, M2
Yao, J2
Keeney, G2
Scott, N1
Cheek, EH1
Davidson, J1
Greene, M1
Martinez, C1
Lehman, J1
Pettry, C1
Reed, E1
Lyke, K2
White, BA2
Diener, C2
Resendis-Antonio, O2
Gransee, J2
Dutta, T2
Petterson, XM2
Boardman, L2
Larson, D2
Nelson, H2
Chia, N2
Shi, B1
Yan, Q1
Tang, J1
Xin, K1
Zhang, J1
Zhu, Y1
Chen, J2
Gao, W1
Shi, J1
Fan, C1
Tian, H1
Priya, S1
Ridlon, J1
French, AJ1
Thibodeau, SN1
Sung, J1
Blekhman, R1
Blachier, F1
Beaumont, M1
Kim, E1
Malagrinò, F1
Zuhra, K1
Mascolo, L1
Mastronicola, D1
Vicente, JB1
Forte, E1
Giuffrè, A1
Módis, K1
Coletta, C2
Asimakopoulou, A1
Szczesny, B1
Chao, C2
Papapetropoulos, A1
Hellmich, MR2
Szabo, C2
Kodela, R1
Nath, N1
Chattopadhyay, M1
Nesbitt, DE1
Velázquez-Martínez, CA1
Kashfi, K1
Colquhoun, A1
Jiang, Z1
Maiangowi, G2
Ashbury, F2
Chen, Y1
Drobina, W1
McLeod, L1
Panaro, L1
Sihota, S1
Tustin, J1
Yacoub, W1
Windey, K1
De Preter, V1
Verbeke, K1
Myung, DS1
Joo, YE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Promephy - Metabolic Fate of Plant-based Proteins[NCT05669612]20 participants (Anticipated)Interventional2023-05-02Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for hydrogen sulfide and Colorectal Neoplasms

ArticleYear
Implications of hydrogen sulfide in colorectal cancer: Mechanistic insights and diagnostic and therapeutic strategies.
    Redox biology, 2023, Volume: 59

    Topics: Colorectal Neoplasms; Humans; Hydrogen Sulfide; Mitochondria

2023
The Role of Microbiota-Derived Metabolites in Colorectal Cancer.
    International journal of molecular sciences, 2023, Apr-28, Volume: 24, Issue:9

    Topics: Animals; Bacteria; Bile Acids and Salts; Colorectal Neoplasms; Fatty Acids, Volatile; Gastrointestin

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Cysteine-derived hydrogen sulfide and gut health: a matter of endogenous or bacterial origin.
    Current opinion in clinical nutrition and metabolic care, 2019, Volume: 22, Issue:1

    Topics: Animals; Colon; Colorectal Neoplasms; Cysteine; Fusobacterium; Gastrointestinal Microbiome; Humans;

2019
The therapeutic potential of cystathionine β-synthetase/hydrogen sulfide inhibition in cancer.
    Antioxidants & redox signaling, 2015, Feb-10, Volume: 22, Issue:5

    Topics: Aminooxyacetic Acid; Animals; Antineoplastic Agents; Cell Proliferation; Colorectal Neoplasms; Cysta

2015
Relevance of protein fermentation to gut health.
    Molecular nutrition & food research, 2012, Volume: 56, Issue:1

    Topics: Ammonia; Animals; Colon; Colorectal Neoplasms; Cresols; Diet; Fermentation; Gastrointestinal Tract;

2012
[Gut microbial influence and probiotics on colorectal cancer].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2012, Volume: 60, Issue:5

    Topics: Animals; Bacteroides; Colorectal Neoplasms; Fatty Acids, Nonesterified; Humans; Hydrogen Sulfide; In

2012

Trials

1 trial available for hydrogen sulfide and Colorectal Neoplasms

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Other Studies

15 other studies available for hydrogen sulfide and Colorectal Neoplasms

ArticleYear
Zinc oxide nanosphere for hydrogen sulfide scavenging and ferroptosis of colorectal cancer.
    Journal of nanobiotechnology, 2021, Nov-27, Volume: 19, Issue:1

    Topics: Animals; Colorectal Neoplasms; Ferroptosis; Glutathione; HCT116 Cells; Humans; Hydrogen Sulfide; Mic

2021
Slow sulfide donor GYY4137 potentiates effect of paclitaxel on colorectal carcinoma cells.
    European journal of pharmacology, 2022, May-05, Volume: 922

    Topics: Adenosine Triphosphate; Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Humans; Hydrogen Sulfide;

2022
A growth chamber for chronic exposure of mammalian cells to H
    Analytical biochemistry, 2023, 07-15, Volume: 673

    Topics: Animals; Cell Proliferation; Colorectal Neoplasms; Humans; Hydrogen Sulfide; Mammals; Oxidation-Redu

2023
H
    Nature communications, 2020, 01-23, Volume: 11, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Colorectal Neoplasms; Cystathionine beta-Synthase; Cystathionine

2020
Magnetic-Photoacoustic Dual-Mode Probe for the Visualization of H
    Analytical chemistry, 2020, 06-16, Volume: 92, Issue:12

    Topics: Animals; Cell Line; Cell Survival; Colorectal Neoplasms; Copper; Ferric Compounds; HCT116 Cells; Hum

2020
Rational design of water-dispersible and biocompatible nanoprobes with H
    Journal of materials chemistry. B, 2020, 07-28, Volume: 8, Issue:28

    Topics: Biocompatible Materials; Colorectal Neoplasms; Fluorescent Dyes; HCT116 Cells; Humans; Hydrogen Sulf

2020
In vitro anticancer activity of hydrogen sulfide and nitric oxide alongside nickel nanoparticle and novel mutations in their genes in CRC patients.
    Scientific reports, 2021, 01-28, Volume: 11, Issue:1

    Topics: Alleles; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; DNA Mutationa

2021
[Research progress of the association of hydrogen sulfide with colorectal cancer and its associated anti-tumor drugs].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2017, Jul-25, Volume: 20, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Carcinogenesis; Colonic Neoplasms; C

2017
Synthesis of multi-omic data and community metabolic models reveals insights into the role of hydrogen sulfide in colon cancer.
    Methods (San Diego, Calif.), 2018, 10-01, Volume: 149

    Topics: Adult; Aged; Aged, 80 and over; Clostridium perfringens; Colorectal Neoplasms; Female; Fusobacterium

2018
Hydrogen Sulfide-Activatable Second Near-Infrared Fluorescent Nanoassemblies for Targeted Photothermal Cancer Therapy.
    Nano letters, 2018, 10-10, Volume: 18, Issue:10

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Colorectal Neoplasms; Fluorescent Dyes; Humans; H

2018
Distinct microbes, metabolites, and ecologies define the microbiome in deficient and proficient mismatch repair colorectal cancers.
    Genome medicine, 2018, 10-31, Volume: 10, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Bacteroides; Colorectal Neoplasms; DNA Mismatch Repair; Female; Huma

2018
Hydrogen Sulfide Oxidation: Adaptive Changes in Mitochondria of SW480 Colorectal Cancer Cells upon Exposure to Hypoxia.
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Cell Hypoxia; Cell Line, Tumor; Colorectal Neoplasms; Humans; Hydrogen Sulfide; Mitochondria; Models

2019
Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-β-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro.
    Nitric oxide : biology and chemistry, 2014, Sep-15, Volume: 41

    Topics: Cell Line; Cell Proliferation; Colorectal Neoplasms; Cystathionine beta-Synthase; Dose-Response Rela

2014
Hydrogen sulfide-releasing naproxen suppresses colon cancer cell growth and inhibits NF-κB signaling.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Colorectal Neoplasms; D

2015
An investigation of cancer incidence in a First Nations community in Alberta, Canada, 1995-2006.
    Chronic diseases in Canada, 2010, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Alberta; Child; Child, Preschool; Colorectal Neoplasms; Environmental Exposure; F

2010