Page last updated: 2024-10-17

hydrogen sulfide and Colonic Neoplasms

hydrogen sulfide has been researched along with Colonic Neoplasms in 27 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
" The impact of H(2)S on mitochondrial energy metabolism crucially depends on the bioavailability of this gaseous molecule and its interplay with the other two gasotransmitters."2.53Bioenergetic relevance of hydrogen sulfide and the interplay between gasotransmitters at human cystathionine β-synthase. ( Arese, M; Forte, E; Giuffrè, A; Malagrinò, F; Sarti, P; Vicente, JB, 2016)
"The main therapy for colon cancer with liver metastasis is chemotherapy based on 5-fluorouracil combined with targeted drugs."1.72The CBS-H ( Chen, S; Guo, S; Huang, Z; Li, J; Liu, Y; Wang, P; Wang, X; Yue, T; Zhu, J, 2022)
"Roflumilast was administered subcutaneously at two doses (1 and 5 mg/kg/day, from day 28 to 42)."1.56Roflumilast counteracts DMH-induced preneoplastic colon damage in albino Wistar rats. ( Ansari, MN; Rastogi, S; Saeedan, AS, 2020)
"Analysis of human colon cancer biopsies and patient-matched normal margin mucosa revealed the selective up-regulation of the H2S-producing enzyme cystathionine-β-synthase (CBS) in colon cancer, resulting in an increased rate of H2S production."1.39Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer. ( Chao, C; Coletta, C; Hellmich, MR; Módis, K; Papapetropoulos, A; Szabo, C; Szczesny, B, 2013)
"Flatus samples from patients with colon cancer and exhaled air samples from patients with lung cancer were analysed using near-edge x-ray fine adsorption structure spectroscopy and compared with those from healthy individuals."1.38Generation of gaseous sulfur-containing compounds in tumour tissue and suppression of gas diffusion as an antitumour treatment. ( Akita, K; Aoki, S; Chiba, Y; Fuji, M; Hosoya, N; Ishii, Y; Ishikawa, H; Kawai, K; Nakajima, M; Ohsaka, T; Okajima, T; Onuma, K; Saeki, Y; Sato, T; Senawongse, P; Shoun, H; Sugawara, Y; Sugiyama, S; Suzuki, T; Takahashi, M; Tsuboi, M; Urushiyama, A; Yagi, S; Yamagishi, K; Yamanaka, T, 2012)
" However, their long-term use is associated with adverse gastrointestinal effects."1.38NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse model. ( Chattopadhyay, M; Kashfi, K; Kodela, R; Olson, KR, 2012)
"In conclusion, NaHS induced human colon cancer cell proliferation."1.36Hydrogen sulfide induces human colon cancer cell proliferation: role of Akt, ERK and p21. ( Cai, WJ; Ju, LH; Wang, C; Wang, MJ; Zhu, YC, 2010)
"Hydrogen sulfide (H(2)S) is a prominent gaseous constituent of the gastrointestinal (GI) tract with known cytotoxic properties."1.33Hydrogen sulfide protects colon cancer cells from chemopreventative agent beta-phenylethyl isothiocyanate induced apoptosis. ( Armstrong, JS; Ming, SH; Moore, PK; Nam, OC; Rose, P; Whiteman, M, 2005)
"In HT-29 cells, a human colon cancer cell line, TST activity and expression were significantly increased by butyrate and by histone deacetylase inhibition, agents that promote HT-29 cell differentiation."1.33Sulfide-detoxifying enzymes in the human colon are decreased in cancer and upregulated in differentiation. ( Eggo, MC; Langman, MJ; Ramasamy, S; Singh, S; Taniere, P, 2006)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (11.11)29.6817
2010's15 (55.56)24.3611
2020's9 (33.33)2.80

Authors

AuthorsStudies
Guo, S2
Li, J3
Huang, Z2
Yue, T5
Zhu, J5
Wang, X7
Liu, Y6
Wang, P6
Chen, S6
Ascenção, K1
Lheimeur, B1
Szabo, C4
Tian, Q2
Song, S1
An, L2
Yang, S2
Huang, G1
Zuo, S2
Liu, J2
Liu, X2
Shi, B1
Ren, N1
Gu, L1
Xu, G1
Wang, R2
Zhu, T1
Zhu, Y1
Fan, C1
Zhao, C1
Tian, H1
Bu, D2
Pan, Y2
Saeedan, AS1
Rastogi, S1
Ansari, MN1
Chang, HW1
Frey, G1
Liu, H1
Xing, C1
Steinman, L1
Boyle, WJ1
Short, JM1
Feng, J1
Ren, WX1
Kong, F1
Dong, YB1
Untereiner, AA1
Pavlidou, A1
Druzhyna, N1
Papapetropoulos, A2
Hellmich, MR3
Rui, X1
Lin, J1
Yang, H1
Tao, C1
Zuhra, K1
Tomé, CS1
Masi, L1
Giardina, G1
Paulini, G1
Malagrinò, F2
Forte, E2
Vicente, JB2
Giuffrè, A2
Coletta, C1
Chao, C1
Módis, K1
Szczesny, B1
Hong, M1
Tang, X1
He, K1
Ridlon, JM2
Wolf, PG1
Gaskins, HR1
Arese, M1
Sarti, P1
Cao, Q1
Zhang, L1
Yang, G1
Xu, C1
Cai, WJ1
Wang, MJ1
Ju, LH1
Wang, C1
Zhu, YC1
Yamagishi, K1
Onuma, K1
Chiba, Y1
Yagi, S1
Aoki, S1
Sato, T1
Sugawara, Y1
Hosoya, N1
Saeki, Y1
Takahashi, M1
Fuji, M1
Ohsaka, T1
Okajima, T1
Akita, K1
Suzuki, T1
Senawongse, P1
Urushiyama, A1
Kawai, K1
Shoun, H1
Ishii, Y1
Ishikawa, H1
Sugiyama, S1
Nakajima, M1
Tsuboi, M1
Yamanaka, T1
Chattopadhyay, M1
Kodela, R1
Olson, KR1
Kashfi, K1
Rose, P1
Moore, PK1
Ming, SH1
Nam, OC1
Armstrong, JS1
Whiteman, M1
Kang, DJ1
Hylemon, PB1
Ramasamy, S1
Singh, S1
Taniere, P1
Langman, MJ1
Eggo, MC1

Reviews

4 reviews available for hydrogen sulfide and Colonic Neoplasms

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Taurocholic acid metabolism by gut microbes and colon cancer.
    Gut microbes, 2016, 05-03, Volume: 7, Issue:3

    Topics: Bile; Cholagogues and Choleretics; Colonic Neoplasms; Deoxycholic Acid; Detergents; Gastrointestinal

2016
Bioenergetic relevance of hydrogen sulfide and the interplay between gasotransmitters at human cystathionine β-synthase.
    Biochimica et biophysica acta, 2016, Volume: 1857, Issue:8

    Topics: Carbon Monoxide; Colonic Neoplasms; Cystathionine beta-Synthase; Electron Transport Complex IV; Gaso

2016
Bile salt biotransformations by human intestinal bacteria.
    Journal of lipid research, 2006, Volume: 47, Issue:2

    Topics: Amidohydrolases; Amino Acid Sequence; Bacteria; Bile Acids and Salts; Biotransformation; Cholic Acid

2006

Trials

1 trial available for hydrogen sulfide and Colonic Neoplasms

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Other Studies

23 other studies available for hydrogen sulfide and Colonic Neoplasms

ArticleYear
The CBS-H
    British journal of cancer, 2022, Volume: 126, Issue:7

    Topics: Animals; Cell Proliferation; Colonic Neoplasms; Cystathionine beta-Synthase; Humans; Hydrogen Sulfid

2022
Regulation of CyR61 expression and release by 3-mercaptopyruvate sulfurtransferase in colon cancer cells.
    Redox biology, 2022, Volume: 56

    Topics: Aminooxyacetic Acid; Antineoplastic Agents; Colonic Neoplasms; Cystathionine; Cystathionine beta-Syn

2022
Engineering of an endogenous hydrogen sulfide responsive smart agent for photoacoustic imaging-guided combination of photothermal therapy and chemotherapy for colon cancer.
    Journal of advanced research, 2022, Volume: 41

    Topics: Animals; Colonic Neoplasms; Curcumin; Hydrogen Sulfide; Mice; Photoacoustic Techniques; Photothermal

2022
Hydrogen Sulfide Creates a Favorable Immune Microenvironment for Colon Cancer.
    Cancer research, 2023, 02-15, Volume: 83, Issue:4

    Topics: Animals; CD8-Positive T-Lymphocytes; Colonic Neoplasms; Cysteine; Hydrogen Sulfide; Immunotherapy; M

2023
Hydrogen Sulfide Creates a Favorable Immune Microenvironment for Colon Cancer.
    Cancer research, 2023, 02-15, Volume: 83, Issue:4

    Topics: Animals; CD8-Positive T-Lymphocytes; Colonic Neoplasms; Cysteine; Hydrogen Sulfide; Immunotherapy; M

2023
Hydrogen Sulfide Creates a Favorable Immune Microenvironment for Colon Cancer.
    Cancer research, 2023, 02-15, Volume: 83, Issue:4

    Topics: Animals; CD8-Positive T-Lymphocytes; Colonic Neoplasms; Cysteine; Hydrogen Sulfide; Immunotherapy; M

2023
Hydrogen Sulfide Creates a Favorable Immune Microenvironment for Colon Cancer.
    Cancer research, 2023, 02-15, Volume: 83, Issue:4

    Topics: Animals; CD8-Positive T-Lymphocytes; Colonic Neoplasms; Cysteine; Hydrogen Sulfide; Immunotherapy; M

2023
Theranostic Nanoplatform with Hydrogen Sulfide Activatable NIR Responsiveness for Imaging-Guided On-Demand Drug Release.
    Angewandte Chemie (International ed. in English), 2019, 11-18, Volume: 58, Issue:47

    Topics: Animals; Apoptosis; Cell Proliferation; Colonic Neoplasms; Drug Liberation; Humans; Hydrogen Sulfide

2019
Inhibition of hydrogen sulfide synthesis reverses acquired resistance to 5-FU through miR-215-5p-EREG/TYMS axis in colon cancer cells.
    Cancer letters, 2019, 12-01, Volume: 466

    Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Cystathionine beta-

2019
Roflumilast counteracts DMH-induced preneoplastic colon damage in albino Wistar rats.
    Human & experimental toxicology, 2020, Volume: 39, Issue:11

    Topics: 1,2-Dimethylhydrazine; Aminopyridines; Animals; Anti-Inflammatory Agents; Antioxidants; Benzamides;

2020
Generating tumor-selective conditionally active biologic anti-CTLA4 antibodies via protein-associated chemical switches.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 03-02, Volume: 118, Issue:9

    Topics: 5'-Nucleotidase; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neo

2021
Endogenous hydrogen sulfide regulates xCT stability through persulfidation of OTUB1 at cysteine 91 in colon cancer cells.
    Neoplasia (New York, N.Y.), 2021, Volume: 23, Issue:5

    Topics: Amino Acid Transport System y+; Animals; Cell Line, Tumor; Colonic Neoplasms; Cysteine; Deubiquitina

2021
A covalent organic framework-based nanoagent for H
    Chemical communications (Cambridge, England), 2021, Jul-28, Volume: 57, Issue:59

    Topics: Animals; Colonic Neoplasms; Copper; HCT116 Cells; Humans; Hydrogen Sulfide; Infrared Rays; Metal-Org

2021
[Research progress of the association of hydrogen sulfide with colorectal cancer and its associated anti-tumor drugs].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2017, Jul-25, Volume: 20, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Carcinogenesis; Colonic Neoplasms; C

2017
Drug resistance induces the upregulation of H
    Biochemical pharmacology, 2018, Volume: 149

    Topics: Aminooxyacetic Acid; Antineoplastic Agents; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cy

2018
The In Situ Sulfidation of Cu
    Angewandte Chemie (International ed. in English), 2018, 11-26, Volume: 57, Issue:48

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; Colonic Neoplasms; Copper; HCT116 Cells; Humans;

2018
    Cells, 2019, 08-04, Volume: 8, Issue:8

    Topics: Acetylcysteine; Cell Line, Tumor; Colonic Neoplasms; Energy Metabolism; Free Radical Scavengers; Hum

2019
Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Jul-23, Volume: 110, Issue:30

    Topics: Animals; Cell Proliferation; Colonic Neoplasms; Cystathionine beta-Synthase; Energy Metabolism; Fema

2013
Endogenously produced hydrogen sulfide supports tumor cell growth and proliferation.
    Cell cycle (Georgetown, Tex.), 2013, Sep-15, Volume: 12, Issue:18

    Topics: Animals; Cell Proliferation; Colonic Neoplasms; Cystathionine beta-Synthase; Energy Metabolism; Fema

2013
[Effect of hydrogen sulfide on human colon cancer SW480 cell proliferation and migration in vitro].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2014, Volume: 34, Issue:5

    Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Humans; Hydrogen Sulfide; Su

2014
Butyrate-stimulated H2S production in colon cancer cells.
    Antioxidants & redox signaling, 2010, May-01, Volume: 12, Issue:9

    Topics: Animals; Butyrates; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cystathionine beta-Synthase;

2010
Hydrogen sulfide induces human colon cancer cell proliferation: role of Akt, ERK and p21.
    Cell biology international, 2010, Apr-14, Volume: 34, Issue:6

    Topics: Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclin D1; Cyclin-Dependent Kinase Inhibito

2010
Generation of gaseous sulfur-containing compounds in tumour tissue and suppression of gas diffusion as an antitumour treatment.
    Gut, 2012, Volume: 61, Issue:4

    Topics: Animals; Antineoplastic Agents; Breath Tests; Cell Proliferation; Chromatography, Gas; Colonic Neopl

2012
NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse model.
    Biochemical and biophysical research communications, 2012, Mar-16, Volume: 419, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Aspirin; Cell Cycle; Cell Proliferation; Colonic Neoplasm

2012
Hydrogen sulfide protects colon cancer cells from chemopreventative agent beta-phenylethyl isothiocyanate induced apoptosis.
    World journal of gastroenterology, 2005, Jul-14, Volume: 11, Issue:26

    Topics: Anticarcinogenic Agents; Apoptosis; Buthionine Sulfoximine; Cell Line, Tumor; Colonic Neoplasms; Hum

2005
Sulfide-detoxifying enzymes in the human colon are decreased in cancer and upregulated in differentiation.
    American journal of physiology. Gastrointestinal and liver physiology, 2006, Volume: 291, Issue:2

    Topics: Cell Differentiation; Cell Line, Tumor; Colonic Neoplasms; Enzyme Activation; Gene Expression Regula

2006