hydrogen sulfide has been researched along with Colitis in 27 studies
Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "During a course of colitis, production of the gaseous mediator hydrogen sulfide (H2S) is markedly up-regulated at sites of mucosal damage and contributes significantly to healing and resolution of inflammation." | 7.81 | Proresolution effects of hydrogen sulfide during colitis are mediated through hypoxia-inducible factor-1α. ( Agbor, TA; Buret, AG; Ferraz, JG; Flannigan, KL; Motta, JP; Wallace, JL; Wang, R, 2015) |
| "Mesalamine is the first-line therapy for colitis, but it lacks potency and is only effective for mild-to-moderate forms of this disease." | 7.74 | Enhanced activity of a hydrogen sulphide-releasing derivative of mesalamine (ATB-429) in a mouse model of colitis. ( Caliendo, G; Cirino, G; Distrutti, E; Fiorucci, S; Mencarelli, A; Orlandi, S; Santagada, V; Santucci, L; Wallace, JL, 2007) |
| "Colitis was induced in mice by intracolonic administration of dinitrobenzenesulfonic acid." | 5.42 | Orally administered allyl sulfides from garlic ameliorate murine colitis. ( Borrelli, F; Clavel, T; Fasolino, I; Haller, D; Izzo, AA; Romano, B, 2015) |
| "Hydrogen sulfide (H2S) is a gaseous mediator that promotes tissue repair and resolution of inflammation." | 5.40 | Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis. ( Agbor, TA; Blackler, RW; Ferraz, JG; Flannigan, KL; Khan, WI; Kim, JJ; Verdu, EF; Wallace, JL, 2014) |
| "Acute colitis was induced using 8% DSS in male BALB/c mice." | 5.37 | Endogenous hydrogen sulfide is an anti-inflammatory molecule in dextran sodium sulfate-induced colitis in mice. ( Handa, O; Hirata, I; Ichikawa, H; Mizushima, K; Naito, Y; Omatsu, T; Suzuki, T; Takagi, T; Ueda, H; Yoshikawa, T, 2011) |
| "Hydrogen sulfide (H(2)S) is an endogenous gaseous mediator of mucosal defense with antiinflammatory effects that promote ulcer healing." | 5.35 | Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats. ( Dicay, M; Martin, GR; McKnight, W; Vong, L; Wallace, JL, 2009) |
| "During a course of colitis, production of the gaseous mediator hydrogen sulfide (H2S) is markedly up-regulated at sites of mucosal damage and contributes significantly to healing and resolution of inflammation." | 3.81 | Proresolution effects of hydrogen sulfide during colitis are mediated through hypoxia-inducible factor-1α. ( Agbor, TA; Buret, AG; Ferraz, JG; Flannigan, KL; Motta, JP; Wallace, JL; Wang, R, 2015) |
| " In the present study, we tested the effects (in rats) of a simple extract of medicinal cannabis (called "MFF") for its ability to promote resolution of colitis, to prevent gastric damage induced by naproxen, and to reduce gastric distention-induced visceral pain." | 3.79 | Pro-resolution, protective and anti-nociceptive effects of a cannabis extract in the rat gastrointestinal tract. ( Ferraz, JG; Flannigan, KL; McKnight, W; Tuitt, D; Wallace, JL; Wang, L, 2013) |
| "2 are involved in the H(2)S-induced mucosal cytoprotection against 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis in rats." | 3.78 | Hydrogen sulfide-induced colonic mucosal cytoprotection involves T-type calcium channel-dependent neuronal excitation in rats. ( Kawabata, A; Kirishi, S; Matsunami, M; Okui, T, 2012) |
| "Mesalamine is the first-line therapy for colitis, but it lacks potency and is only effective for mild-to-moderate forms of this disease." | 3.74 | Enhanced activity of a hydrogen sulphide-releasing derivative of mesalamine (ATB-429) in a mouse model of colitis. ( Caliendo, G; Cirino, G; Distrutti, E; Fiorucci, S; Mencarelli, A; Orlandi, S; Santagada, V; Santucci, L; Wallace, JL, 2007) |
| "Colitis was induced in mice by intracolonic administration of dinitrobenzenesulfonic acid." | 1.42 | Orally administered allyl sulfides from garlic ameliorate murine colitis. ( Borrelli, F; Clavel, T; Fasolino, I; Haller, D; Izzo, AA; Romano, B, 2015) |
| "Hydrogen sulfide (H2S) is a gaseous mediator that promotes tissue repair and resolution of inflammation." | 1.40 | Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis. ( Agbor, TA; Blackler, RW; Ferraz, JG; Flannigan, KL; Khan, WI; Kim, JJ; Verdu, EF; Wallace, JL, 2014) |
| "Acute colitis was induced using 8% DSS in male BALB/c mice." | 1.37 | Endogenous hydrogen sulfide is an anti-inflammatory molecule in dextran sodium sulfate-induced colitis in mice. ( Handa, O; Hirata, I; Ichikawa, H; Mizushima, K; Naito, Y; Omatsu, T; Suzuki, T; Takagi, T; Ueda, H; Yoshikawa, T, 2011) |
| "Hydrogen sulfide (H(2)S) is an important modulator of many aspects of digestive function, both in health and disease." | 1.37 | Eukaryotic and prokaryotic contributions to colonic hydrogen sulfide synthesis. ( Flannigan, KL; McCoy, KD; Wallace, JL, 2011) |
| "Hydrogen sulfide (H(2)S) is an endogenous gaseous mediator of mucosal defense with antiinflammatory effects that promote ulcer healing." | 1.35 | Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats. ( Dicay, M; Martin, GR; McKnight, W; Vong, L; Wallace, JL, 2009) |
| "Hydrogen sulfide (H(2)S) functions as a neuromodulator, but whether it modulates visceral perception and pain is unknown." | 1.33 | Evidence that hydrogen sulfide exerts antinociceptive effects in the gastrointestinal tract by activating KATP channels. ( Antonelli, E; Cirino, G; Distrutti, E; Fiorucci, S; Mencarelli, A; Morelli, A; Orlandi, S; Renga, B; Roviezzo, F; Sediari, L; Wallace, JL, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (25.93) | 29.6817 |
| 2010's | 18 (66.67) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, J | 1 |
| Cen, L | 1 |
| Zhang, X | 1 |
| Tang, C | 1 |
| Chen, Y | 2 |
| Zhang, Y | 1 |
| Yu, M | 1 |
| Lu, C | 1 |
| Li, M | 1 |
| Li, S | 1 |
| Lin, B | 1 |
| Zhang, T | 1 |
| Song, X | 1 |
| Yu, C | 1 |
| Wu, H | 1 |
| Shen, Z | 1 |
| Guo, S | 1 |
| Huang, Z | 1 |
| Zhu, J | 1 |
| Yue, T | 1 |
| Wang, X | 1 |
| Pan, Y | 1 |
| Bu, D | 1 |
| Liu, Y | 2 |
| Wang, P | 1 |
| Chen, S | 1 |
| Qin, M | 1 |
| Long, F | 1 |
| Wu, W | 1 |
| Yang, D | 1 |
| Huang, M | 1 |
| Xiao, C | 1 |
| Chen, X | 2 |
| Liu, X | 1 |
| Zhu, YZ | 1 |
| Wallace, JL | 10 |
| Flannigan, KL | 6 |
| McKnight, W | 2 |
| Wang, L | 1 |
| Ferraz, JG | 4 |
| Tuitt, D | 1 |
| Wang, R | 3 |
| Agbor, TA | 3 |
| Blackler, RW | 2 |
| Kim, JJ | 1 |
| Khan, WI | 1 |
| Verdu, EF | 1 |
| Tsubota, M | 1 |
| Kawabata, A | 3 |
| Fasolino, I | 1 |
| Izzo, AA | 1 |
| Clavel, T | 1 |
| Romano, B | 1 |
| Haller, D | 1 |
| Borrelli, F | 1 |
| Motta, JP | 2 |
| Buret, AG | 2 |
| Beatty, JK | 1 |
| Workentine, ML | 1 |
| Da Silva, GJ | 1 |
| Yang, R | 1 |
| Qu, C | 1 |
| Zhou, Y | 2 |
| Konkel, JE | 1 |
| Shi, S | 2 |
| Chen, C | 1 |
| Liu, S | 1 |
| Liu, D | 1 |
| Zandi, E | 1 |
| Chen, W | 1 |
| Oh, SA | 1 |
| Li, MO | 1 |
| Liu, XS | 1 |
| Zhao, H | 1 |
| Yan, R | 1 |
| Zhou, X | 1 |
| Ji, F | 1 |
| Zhang, B | 1 |
| Vong, L | 1 |
| Dicay, M | 1 |
| Martin, GR | 1 |
| Schemann, M | 1 |
| Grundy, D | 1 |
| Taniguchi, E | 1 |
| Matsunami, M | 2 |
| Kimura, T | 1 |
| Yonezawa, D | 1 |
| Ishiki, T | 1 |
| Sekiguchi, F | 1 |
| Nishikawa, H | 1 |
| Maeda, Y | 1 |
| Ishikura, H | 1 |
| Coffey, JC | 1 |
| Docherty, NG | 1 |
| O'Connell, PR | 1 |
| Hirata, I | 1 |
| Naito, Y | 1 |
| Takagi, T | 1 |
| Mizushima, K | 1 |
| Suzuki, T | 1 |
| Omatsu, T | 1 |
| Handa, O | 1 |
| Ichikawa, H | 1 |
| Ueda, H | 1 |
| Yoshikawa, T | 1 |
| McCoy, KD | 1 |
| Kirishi, S | 1 |
| Okui, T | 1 |
| Steidle, J | 1 |
| Würner, L | 1 |
| Diener, M | 1 |
| Gade, AR | 1 |
| Kang, M | 1 |
| Akbarali, HI | 1 |
| Distrutti, E | 2 |
| Sediari, L | 1 |
| Mencarelli, A | 2 |
| Renga, B | 1 |
| Orlandi, S | 2 |
| Antonelli, E | 1 |
| Roviezzo, F | 1 |
| Morelli, A | 1 |
| Cirino, G | 2 |
| Fiorucci, S | 2 |
| Caliendo, G | 1 |
| Santagada, V | 1 |
| Santucci, L | 1 |
| Furne, JK | 1 |
| Suarez, FL | 1 |
| Ewing, SL | 1 |
| Springfield, J | 1 |
| Levitt, MD | 1 |
2 reviews available for hydrogen sulfide and Colitis
| Article | Year |
|---|---|
[Role of hydrogen sulfide, a gasotransmitter, in colonic pain and inflammation].
Topics: Animals; Colitis; Gasotransmitters; Humans; Hydrogen Sulfide; Inflammation; Pain; Signal Transductio | 2014 |
Physiological and pathophysiological roles of hydrogen sulfide in the gastrointestinal tract.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Gastrointestinal Tract; Humans; Hydrogen Sulfide; Inflam | 2010 |
25 other studies available for hydrogen sulfide and Colitis
| Article | Year |
|---|---|
MPST deficiency promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel disease via AKT.
Topics: Animals; Apoptosis; Colitis; Cytokines; Dextran Sulfate; Epithelial Cells; HT29 Cells; Humans; Hydro | 2022 |
CBS-H
Topics: Animals; Colitis; Cyclooxygenase 2; Humans; Hydrogen Sulfide; Inflammation; Lipopolysaccharides; Mic | 2023 |
Hydrogen sulfide protects against DSS-induced colitis by inhibiting NLRP3 inflammasome.
Topics: Animals; Anti-Inflammatory Agents; Caspase 1; Colitis; Colon; Cystathionine gamma-Lyase; Dextran Sul | 2019 |
Pro-resolution, protective and anti-nociceptive effects of a cannabis extract in the rat gastrointestinal tract.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cannabis; Colitis; Gastrointestinal Tr | 2013 |
Enhanced synthesis and diminished degradation of hydrogen sulfide in experimental colitis: a site-specific, pro-resolution mechanism.
Topics: Animals; Colitis; Colon; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Disease Models, Ani | 2013 |
Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis.
Topics: Animals; Colitis; Colon; Dextran Sulfate; Diet; Disease Progression; Humans; Hydrogen Sulfide; Hyper | 2014 |
Orally administered allyl sulfides from garlic ameliorate murine colitis.
Topics: Administration, Oral; Allyl Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzenesulf | 2015 |
Proresolution effects of hydrogen sulfide during colitis are mediated through hypoxia-inducible factor-1α.
Topics: Allyl Compounds; Animals; Benzenesulfonates; Colitis; Cystathionine gamma-Lyase; Disease Models, Ani | 2015 |
Hydrogen sulfide protects from colitis and restores intestinal microbiota biofilm and mucus production.
Topics: Animals; Biofilms; Colitis; Dextran Sulfate; Gasotransmitters; Gastrointestinal Microbiome; Humans; | 2015 |
Hydrogen Sulfide Promotes Tet1- and Tet2-Mediated Foxp3 Demethylation to Drive Regulatory T Cell Differentiation and Maintain Immune Homeostasis.
Topics: Adoptive Transfer; Animals; CCAAT-Binding Factor; Cell Differentiation; Colitis; Dioxygenases; DNA M | 2015 |
TETs Link Hydrogen Sulfide to Immune Tolerance.
Topics: Animals; Colitis; DNA-Binding Proteins; Forkhead Transcription Factors; Humans; Hydrogen Sulfide; Pr | 2015 |
Hydrogen sulfide from a NaHS source attenuates dextran sulfate sodium (DSS)-induced inflammation via inhibiting nuclear factor-κB.
Topics: Animals; Caco-2 Cells; Colitis; Cytokines; Dextran Sulfate; Humans; Hydrogen Sulfide; Immunoglobulin | 2016 |
Hydrogen sulfide improves colonic barrier integrity in DSS-induced inflammation in Caco-2 cells and mice.
Topics: Animals; Caco-2 Cells; Cell Membrane Permeability; Colitis; Colon; Cystathionine beta-Synthase; Dext | 2016 |
Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats.
Topics: Analysis of Variance; Animals; Biomarkers; Biopsy, Needle; Colitis; Cyclooxygenase 1; Cyclooxygenase | 2009 |
Role of hydrogen sulfide in visceral nociception.
Topics: Animals; Calcium Channels; Colitis; Colon; Hydrogen Sulfide; Mice; Models, Animal; Nociceptors; Pain | 2009 |
Rhodanese, but not cystathionine-gamma-lyase, is associated with dextran sulfate sodium-evoked colitis in mice: a sign of impaired colonic sulfide detoxification?
Topics: Anemia; Animals; Blotting, Western; Colitis; Colon; Cystathionine gamma-Lyase; Dextran Sulfate; Eryt | 2009 |
Hydrogen sulphide: an increasing need for scientific equipoise.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Colon; Disease Models, Animal; Dose-Response Relationshi | 2009 |
Endogenous hydrogen sulfide is an anti-inflammatory molecule in dextran sodium sulfate-induced colitis in mice.
Topics: Alkynes; Animals; Colitis; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Dextran Sulfate; | 2011 |
Eukaryotic and prokaryotic contributions to colonic hydrogen sulfide synthesis.
Topics: Animals; Bacteria; Colitis; Colon; Feces; Germ-Free Life; Hydrogen Sulfide; Male; Mice; Rats; Rats, | 2011 |
Hydrogen sulfide-induced colonic mucosal cytoprotection involves T-type calcium channel-dependent neuronal excitation in rats.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Capsaicin; Colitis; Colon; Cystathionin | 2012 |
Altered response to hydrogen sulphide during experimental colitis in rats.
Topics: Aminopyridines; Analgesics; Animals; Colitis; Diet; Female; Hydrogen Sulfide; Inflammation; Intestin | 2013 |
Hydrogen sulfide as an allosteric modulator of ATP-sensitive potassium channels in colonic inflammation.
Topics: Allosteric Regulation; Animals; ATP-Binding Cassette Transporters; Colitis; Colon; Cromakalim; Hydro | 2013 |
Evidence that hydrogen sulfide exerts antinociceptive effects in the gastrointestinal tract by activating KATP channels.
Topics: Air Pollutants; Analgesics; Animals; ATP-Binding Cassette Transporters; Behavior, Animal; Colitis; C | 2006 |
Enhanced activity of a hydrogen sulphide-releasing derivative of mesalamine (ATB-429) in a mouse model of colitis.
Topics: Animals; Anti-Inflammatory Agents; Chemokines; Colitis; Colon; Cytokines; Disease Models, Animal; Di | 2007 |
Binding of hydrogen sulfide by bismuth does not prevent dextran sulfate-induced colitis in rats.
Topics: Animals; Bismuth; Colitis; Colon; Dextran Sulfate; Feces; Hydrogen Sulfide; Male; Organometallic Com | 2000 |