Page last updated: 2024-10-17

hydrogen sulfide and Cognitive Dysfunction

hydrogen sulfide has been researched along with Cognitive Dysfunction in 20 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Cognitive Dysfunction: Diminished or impaired mental and/or intellectual function.

Research Excerpts

ExcerptRelevanceReference
"Hydrogen sulfide (H2S) has attracted interest as a gaseous mediator involved in diverse processes in the nervous system, particularly with respect to learning and memory."5.43The hydrogen sulfide releasing compounds ATB-346 and diallyl trisulfide attenuate streptozotocin-induced cognitive impairment, neuroinflammation, and oxidative stress in rats: involvement of asymmetric dimethylarginine. ( El Azhary, NM; Mostafa, DK; Nasra, RA, 2016)
"Cognitive dysfunction was detected in the hepatic I/R group, and this dysfunction was associated with a decrease in the mRNA and protein levels of the NR2B subunit of the NMDA receptors in the hippocampus."5.43Effects of hydrogen sulfide on cognitive dysfunction and NR2B in rats. ( Li, JX; Li, Q; Tu, FP; Wang, J, 2016)
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"To investigate the effect and mechanisms of exogenous hydrogen sulfide in surgery-induced neuroinflammatory cognitive dysfunction."3.96Exogenous hydrogen sulfide alleviates surgery-induced neuroinflammatory cognitive impairment in adult mice by inhibiting NO signaling. ( Gao, S; Li, C; Yin, L, 2020)
"Hydrogen sulfide (H2S) has attracted interest as a gaseous mediator involved in diverse processes in the nervous system, particularly with respect to learning and memory."1.43The hydrogen sulfide releasing compounds ATB-346 and diallyl trisulfide attenuate streptozotocin-induced cognitive impairment, neuroinflammation, and oxidative stress in rats: involvement of asymmetric dimethylarginine. ( El Azhary, NM; Mostafa, DK; Nasra, RA, 2016)
"Cognitive dysfunction was detected in the hepatic I/R group, and this dysfunction was associated with a decrease in the mRNA and protein levels of the NR2B subunit of the NMDA receptors in the hippocampus."1.43Effects of hydrogen sulfide on cognitive dysfunction and NR2B in rats. ( Li, JX; Li, Q; Tu, FP; Wang, J, 2016)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (45.00)24.3611
2020's11 (55.00)2.80

Authors

AuthorsStudies
Tian, Q1
Tang, HL1
Tang, YY3
Zhang, P3
Kang, X1
Zou, W3
Tang, XQ4
Hamidizad, Z1
Kadkhodaee, M1
Karimian, SM1
Ranjbaran, M1
Heidari, F1
Bakhshi, E1
Kianian, F1
Zahedi, E1
Seifi, B1
Chen, J1
Chen, Z1
Yu, D1
Yan, Y1
Hao, X1
Zhang, M1
Zhu, T1
Li, X3
Zhuang, YY1
Wu, L1
Xie, M1
Gu, HF1
Wang, B1
Yin, L1
Gao, S2
Li, C1
Lv, S1
Wu, N1
Wang, Q1
Yang, LH1
Yakovleva, O1
Bogatova, K1
Mukhtarova, R1
Yakovlev, A1
Shakhmatova, V1
Gerasimova, E1
Ziyatdinova, G1
Hermann, A1
Sitdikova, G1
Zhuge, W1
Zhuge, Q1
Wang, W1
Lu, X1
You, R1
Liu, L1
Yu, H1
Wang, J2
Wang, X1
Ye, Y1
Ding, S1
Disbrow, E1
Stokes, KY1
Ledbetter, C1
Patterson, J1
Kelley, R1
Pardue, S1
Reekes, T1
Larmeu, L1
Batra, V1
Yuan, S1
Cvek, U1
Trutschl, M1
Kilgore, P1
Alexander, JS1
Kevil, CG1
Jiang, L1
Lan, F1
Chen, YJ1
Ma, S1
Zhong, D1
Ma, P1
Li, G1
Hua, W1
Sun, Y1
Liu, N1
Zhang, L1
Zhang, W1
Kumar, M1
Modi, M1
Sandhir, R1
Guo, HY1
Wang, AP1
Wei, HJ1
Li, MH1
Wang, CY1
Xiong, JW1
Wei, B1
Li, YK1
Zhan, JQ1
Jiang, SZ1
Chen, HB1
Yan, K1
Yu, B1
Yang, YJ1
Mun, J1
Kang, HM1
Jung, J1
Park, C1
Mostafa, DK1
El Azhary, NM1
Nasra, RA1
Kumar, G1
Chhabra, A1
Mishra, S1
Kalam, H1
Kumar, D1
Meena, R1
Ahmad, Y1
Bhargava, K1
Prasad, DN1
Sharma, M1
Tu, FP1
Li, JX1
Li, Q1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Plasma Hydrogen Sulfide as a Biomarker for Alzheimer's Disease and Related Dementias[NCT05060848]100 participants (Anticipated)Observational2021-04-01Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for hydrogen sulfide and Cognitive Dysfunction

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Role of hydrogen sulfide in cerebrovascular alteration during aging.
    Archives of pharmacal research, 2019, Volume: 42, Issue:5

    Topics: Aging; Animals; Apoptosis; Brain; Cellular Senescence; Cerebrovascular Circulation; Cognitive Dysfun

2019

Trials

1 trial available for hydrogen sulfide and Cognitive Dysfunction

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Other Studies

18 other studies available for hydrogen sulfide and Cognitive Dysfunction

ArticleYear
Hydrogen Sulfide Attenuates the Cognitive Dysfunction in Parkinson's Disease Rats via Promoting Hippocampal Microglia M2 Polarization by Enhancement of Hippocampal Warburg Effect.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Animals; Cognitive Dysfunction; Hippocampus; Humans; Hydrogen Sulfide; Male; Microglia; Parkinson Di

2022
Therapeutic effects of CORM3 and NaHS in chronic kidney disease induced cognitive impairment via the interaction between carbon monoxide and hydrogen sulfide on Nrf2/HO-1 signaling pathway in rats.
    Chemico-biological interactions, 2022, Dec-01, Volume: 368

    Topics: Animals; Carbon Monoxide; Cognitive Dysfunction; Heme Oxygenase-1; Hydrogen Sulfide; NF-E2-Related F

2022
Neuroprotective Effect of Hydrogen Sulfide Subchronic Treatment Against TBI-Induced Ferroptosis and Cognitive Deficits Mediated Through Wnt Signaling Pathway.
    Cellular and molecular neurobiology, 2023, Volume: 43, Issue:8

    Topics: Brain Injuries, Traumatic; Cognition; Cognitive Dysfunction; Ferroptosis; Humans; Hydrogen Sulfide;

2023
Hydrogen Sulfide Ameliorates Cognitive Dysfunction in Formaldehyde-Exposed Rats: Involvement in the Upregulation of Brain-Derived Neurotrophic Factor.
    Neuropsychobiology, 2020, Volume: 79, Issue:2

    Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; CA1 Region, Hippocampal; Cognitive Dys

2020
Exogenous hydrogen sulfide alleviates surgery-induced neuroinflammatory cognitive impairment in adult mice by inhibiting NO signaling.
    BMC anesthesiology, 2020, 01-09, Volume: 20, Issue:1

    Topics: Animals; Brain Chemistry; Cognitive Dysfunction; Encephalitis; Enzyme Inhibitors; Hippocampus; Hydro

2020
Endogenous hydrogen sulfide alleviates methotrexate-induced cognitive impairment by attenuating endoplasmic reticulum stress-induced apoptosis via CHOP and caspase-12.
    Fundamental & clinical pharmacology, 2020, Volume: 34, Issue:5

    Topics: Animals; Apoptosis; Cognitive Dysfunction; Doublecortin Protein; Endoplasmic Reticulum Stress; Hippo

2020
Hydrogen Sulfide Alleviates Anxiety, Motor, and Cognitive Dysfunctions in Rats with Maternal Hyperhomocysteinemia via Mitigation of Oxidative Stress.
    Biomolecules, 2020, 07-02, Volume: 10, Issue:7

    Topics: Animals; Anxiety; Cognitive Dysfunction; Cystathionine beta-Synthase; Female; Homocysteine; Hydrogen

2020
Hydrogen sulphide ameliorates dopamine-induced astrocytic inflammation and neurodegeneration in minimal hepatic encephalopathy.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:23

    Topics: Animals; Apoptosis; Astrocytes; bcl-Associated Death Protein; bcl-X Protein; Behavior, Animal; Bioma

2020
Plasma hydrogen sulfide: A biomarker of Alzheimer's disease and related dementias.
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2021, Volume: 17, Issue:8

    Topics: Aged; Alzheimer Disease; Biomarkers; Cognitive Dysfunction; Female; Humans; Hydrogen Sulfide; Magnet

2021
H
    Neurochemical research, 2021, Volume: 46, Issue:8

    Topics: Animals; Autophagy; Cognitive Dysfunction; Hippocampus; Hydrogen Sulfide; Male; Memory; Morris Water

2021
Exogenous Hydrogen Sulfide Ameliorates Diabetes-Associated Cognitive Decline by Regulating the Mitochondria-Mediated Apoptotic Pathway and IL-23/IL-17 Expression in db/db Mice.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 41, Issue:5

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cognitive Dysfunction; Diabetes Complications; Di

2017
Hydrogen sulfide attenuates homocysteine-induced cognitive deficits and neurochemical alterations by improving endogenous hydrogen sulfide levels.
    BioFactors (Oxford, England), 2017, May-06, Volume: 43, Issue:3

    Topics: Animals; Cerebral Cortex; Cognition; Cognitive Dysfunction; Cystathionine beta-Synthase; Cystathioni

2017
Significance of interleukin and matrix metalloproteinase in patients with cognitive dysfunction after single valve replacement.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:13

    Topics: Aged; Aged, 80 and over; Anesthesia, General; Biomarkers; Case-Control Studies; Cognitive Dysfunctio

2017
Role of silent information regulator 1 in the protective effect of hydrogen sulfide on homocysteine-induced cognitive dysfunction: Involving reduction of hippocampal ER stress.
    Behavioural brain research, 2018, 04-16, Volume: 342

    Topics: Animals; Cognitive Dysfunction; Endoplasmic Reticulum Stress; Hippocampus; Homocysteine; Hydrogen Su

2018
Decreased plasma levels of gasotransmitter hydrogen sulfide in patients with schizophrenia: correlation with psychopathology and cognition.
    Psychopharmacology, 2018, Volume: 235, Issue:8

    Topics: Adult; Biomarkers; Cognition; Cognitive Dysfunction; Executive Function; Female; Gasotransmitters; H

2018
The hydrogen sulfide releasing compounds ATB-346 and diallyl trisulfide attenuate streptozotocin-induced cognitive impairment, neuroinflammation, and oxidative stress in rats: involvement of asymmetric dimethylarginine.
    Canadian journal of physiology and pharmacology, 2016, Volume: 94, Issue:7

    Topics: Allyl Compounds; Animals; Arginine; Cognitive Dysfunction; Hydrogen Sulfide; Inflammation; Inflammat

2016
H2S Regulates Hypobaric Hypoxia-Induced Early Glio-Vascular Dysfunction and Neuro-Pathophysiological Effects.
    EBioMedicine, 2016, Volume: 6

    Topics: Altitude Sickness; Animals; Cerebrovascular Circulation; Cognitive Dysfunction; Disease Models, Anim

2016
Effects of hydrogen sulfide on cognitive dysfunction and NR2B in rats.
    The Journal of surgical research, 2016, Volume: 205, Issue:2

    Topics: Animals; Biomarkers; Blotting, Western; Cognitive Dysfunction; Drug Administration Schedule; Hippoca

2016