hydrogen sulfide has been researched along with Cirrhosis in 46 studies
Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Literature was collected from PubMed until February 2019, using the search terms including "Hydrogen sulfide," "Chronic kidney disease," "Renal interstitial fibrosis," "Kidney disease," "Inflammation factor," "Oxidative stress," "Epithelial-to-mesenchymal transition," "H2S donor," "Hypertensive kidney dysfunction," "Myofibroblasts," "Vascular remodeling," "transforming growth factor (TGF)-beta/Smads signaling," and "Sulfate potassium channels." | 9.01 | Involvement of hydrogen sulfide in the progression of renal fibrosis. ( Huang, L; Peng, ZZ; Qin, J; Tang, WB; Tao, LJ; Tu, JK; Wang, W; Wang, Y; Xiao, XC; Xie, YY; Xing, QQ; Xu, H; Yuan, QJ; Yuan, XN, 2019) |
| "Hydrogen sulfide is a critical endogenous signaling molecule that exerts protective effects in the setting of heart failure." | 8.31 | Hydrogen Sulfide Modulates Endothelial-Mesenchymal Transition in Heart Failure. ( Beck, KF; Elrod, JW; Goodchild, TT; Katsouda, A; LaPenna, KB; Lefer, DJ; Li, Z; Papapetropoulos, A; Pfeilschifter, J; Sharp, TE; Xia, H; Xian, M; Xu, S, 2023) |
| "The aim of the present study was to determine the role of hydrogen sulfide (H2S) in improving myocardial fibrosis and its effects on oxidative stress, endoplasmic reticulum (ER) stress and cell apoptosis in diabetic rats, by regulating the Janus kinase̸signal transducer and activator of transcription (JAK̸STAT) signaling pathway." | 7.88 | Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway. ( Chu, C; Jiang, Z; Li, Y; Li, Z; Liang, B; Liu, M; Yang, J, 2018) |
| "The present study aimed to explore the effect of hydrogen sulfide (H2S) on renal tissue fibrosis and its mechanism in diabetic rats." | 7.85 | Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats. ( Chu, C; Li, F; Li, L; Li, Y; Li, Z; Liang, B; Liu, M; Xiao, T; Yang, J; Zeng, O, 2017) |
| "To explore the eff ect of hydrogen sulfide (H2S) on protein kinase C α (PKCα) and heat shock protein 70 (HSP70) expression and myocardial fibrosis in diabetic rats." | 7.81 | [Effect of hydrogen sulfide on myocardial fibrosis and expression of PKCα and HSP70 in diabetic rats]. ( Li, F; Luo, J; Wu, Z; Xiao, T; Yang, J; Zhang, J, 2015) |
| "To explore the effects of hydrogen sulfide (H(2)S) on myocardial fibrosis and expressions of MAPK1/3 and MMP-8 in diabetic rats." | 7.81 | [Effects of hydrogen sulfide on myocardial fibrosis and MAPK1/3 and MMP-8 expression in diabetic rats]. ( Li, F; Luo, J; Wu, ZX; Xiao, T; Yang, J; Zeng, O; Zhang, JJ, 2015) |
| "In order to explore the effects of hydrogen sulfide (H2S) on myocardial fibrosis in diabetic rats and its underlying mechanisms, intraperitoneal injections of streptozotocin were used to establish the diabetes models and sodium hydrosulfide (NaHS) was used as an exogenous donor of H2S." | 7.81 | Effects of hydrogen sulfide on myocardial fibrosis in diabetic rats: Changes in matrix metalloproteinases parameters. ( Li, F; Luo, J; Wu, Z; Xiao, T; Yang, J; Zeng, O, 2015) |
| " The goal of the present study was to determine the therapeutic potential of a stable, long-acting H2S donor, diallyl trisulfide, in a model of pressure-overload heart failure and to assess the effects of chronic H2S therapy on myocardial vascular density and angiogenesis." | 7.79 | Hydrogen sulfide attenuates cardiac dysfunction after heart failure via induction of angiogenesis. ( Bhushan, S; Bir, SC; Calvert, JW; Kevil, CG; Kondo, K; Lefer, DJ; Murohara, T; Polhemus, D, 2013) |
| " Collectively, exercise restored bioavailability of hydrogen sulfide in the heart of aged rats, which partly explained the benefits of exercise against myocardial fibrosis of aged population." | 5.48 | Chronic aerobic exercise training alleviates myocardial fibrosis in aged rats through restoring bioavailability of hydrogen sulfide. ( Liu, HM; Liu, JD; Ma, N; Wang, XZ; Xia, T, 2018) |
| "Myocardial fibrosis is one of the most important pathological features of alcoholic cardiomyopathy (ACM)." | 5.46 | Hydrogen sulfide alleviates myocardial fibrosis in mice with alcoholic cardiomyopathy by downregulating autophagy. ( Li, Z; Liang, B; Liu, M; Liu, S; Long, J; Xiao, T; Yang, J, 2017) |
| "Myocardial fibrosis is the predominant pathological characteristic of diabetic myocardial damage." | 5.43 | Effects of hydrogen sulfide on myocardial fibrosis and PI3K/AKT1-regulated autophagy in diabetic rats. ( Li, F; Luo, J; Wu, Z; Xiao, T; Yang, J; Zeng, O, 2016) |
| "Hydrogen sulfide has recently been found decreased in chronic kidney disease." | 5.40 | Hydrogen sulfide inhibits the renal fibrosis of obstructive nephropathy. ( Hu, LF; Li, Q; Liu, CF; Peng, H; Shen, HY; Shi, YB; Song, K; Wang, F; Zheng, HF, 2014) |
| "Cirrhosis was induced by surgical ligation of bile duct in rats." | 5.38 | The role of endogenous hydrogen sulfide in pathogenesis of chronotropic dysfunction in rats with cirrhosis. ( Babaei-Karamshahlou, M; Hajizadeh, S; Hooshmand, B; Mani, AR, 2012) |
| "Hydrogen sulfide (H2S) has been recently found to be an endogenous signaling gasotransmitter." | 5.38 | Hydrogen sulfide attenuates cardiac hypertrophy and fibrosis induced by abdominal aortic coarctation in rats. ( Huang, J; Huang, X; Jin, H; Wang, D; Zheng, J, 2012) |
| "Literature was collected from PubMed until February 2019, using the search terms including "Hydrogen sulfide," "Chronic kidney disease," "Renal interstitial fibrosis," "Kidney disease," "Inflammation factor," "Oxidative stress," "Epithelial-to-mesenchymal transition," "H2S donor," "Hypertensive kidney dysfunction," "Myofibroblasts," "Vascular remodeling," "transforming growth factor (TGF)-beta/Smads signaling," and "Sulfate potassium channels." | 5.01 | Involvement of hydrogen sulfide in the progression of renal fibrosis. ( Huang, L; Peng, ZZ; Qin, J; Tang, WB; Tao, LJ; Tu, JK; Wang, W; Wang, Y; Xiao, XC; Xie, YY; Xing, QQ; Xu, H; Yuan, QJ; Yuan, XN, 2019) |
| "Hydrogen sulfide is a critical endogenous signaling molecule that exerts protective effects in the setting of heart failure." | 4.31 | Hydrogen Sulfide Modulates Endothelial-Mesenchymal Transition in Heart Failure. ( Beck, KF; Elrod, JW; Goodchild, TT; Katsouda, A; LaPenna, KB; Lefer, DJ; Li, Z; Papapetropoulos, A; Pfeilschifter, J; Sharp, TE; Xia, H; Xian, M; Xu, S, 2023) |
| "OBJECTIVETo investigate the roles and underlying mechanism of exogenous H2S (hydrogen sulfide) in attenuating the myocardial fibrosis in diabetic rats." | 3.91 | H2S attenuates the myocardial fibrosis in diabetic rats through modulating PKC-ERK1/2MAPK signaling pathway. ( Chu, C; Liu, M; Liu, S; Long, J; Tan, W; Tang, F; Xiao, T; Yang, J, 2019) |
| "The aim of the present study was to determine the role of hydrogen sulfide (H2S) in improving myocardial fibrosis and its effects on oxidative stress, endoplasmic reticulum (ER) stress and cell apoptosis in diabetic rats, by regulating the Janus kinase̸signal transducer and activator of transcription (JAK̸STAT) signaling pathway." | 3.88 | Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway. ( Chu, C; Jiang, Z; Li, Y; Li, Z; Liang, B; Liu, M; Yang, J, 2018) |
| "The present study aimed to explore the effect of hydrogen sulfide (H2S) on renal tissue fibrosis and its mechanism in diabetic rats." | 3.85 | Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats. ( Chu, C; Li, F; Li, L; Li, Y; Li, Z; Liang, B; Liu, M; Xiao, T; Yang, J; Zeng, O, 2017) |
| "Hydrogen sulfide (H2S) ameliorates cardiac fibrosis in several models by suppressing endoplasmic reticulum (ER) stress." | 3.83 | Hydrogen sulfide suppresses endoplasmic reticulum stress-induced endothelial-to-mesenchymal transition through Src pathway. ( Chen, YX; Gu, ZJ; Mai, JT; Qiu, Q; Wang, JF; Wang, XQ; Yang, Y; Ying, R, 2016) |
| "Hydrogen sulfide (H2S) can protect against hepatic ischemia-reperfusion injury (HIR)." | 3.83 | Silymarin preconditioning protected insulin resistant rats from liver ischemia-reperfusion injury: role of endogenous H2S. ( Mahmoud, MF; Shaheen, MA; Younis, NN, 2016) |
| "To explore the eff ect of hydrogen sulfide (H2S) on protein kinase C α (PKCα) and heat shock protein 70 (HSP70) expression and myocardial fibrosis in diabetic rats." | 3.81 | [Effect of hydrogen sulfide on myocardial fibrosis and expression of PKCα and HSP70 in diabetic rats]. ( Li, F; Luo, J; Wu, Z; Xiao, T; Yang, J; Zhang, J, 2015) |
| "To explore the effects of hydrogen sulfide (H(2)S) on myocardial fibrosis and expressions of MAPK1/3 and MMP-8 in diabetic rats." | 3.81 | [Effects of hydrogen sulfide on myocardial fibrosis and MAPK1/3 and MMP-8 expression in diabetic rats]. ( Li, F; Luo, J; Wu, ZX; Xiao, T; Yang, J; Zeng, O; Zhang, JJ, 2015) |
| "In order to explore the effects of hydrogen sulfide (H2S) on myocardial fibrosis in diabetic rats and its underlying mechanisms, intraperitoneal injections of streptozotocin were used to establish the diabetes models and sodium hydrosulfide (NaHS) was used as an exogenous donor of H2S." | 3.81 | Effects of hydrogen sulfide on myocardial fibrosis in diabetic rats: Changes in matrix metalloproteinases parameters. ( Li, F; Luo, J; Wu, Z; Xiao, T; Yang, J; Zeng, O, 2015) |
| "Accumulating evidence has demonstrated that hydrogen sulfide (H2S) plays critical roles in the pathogenesis of chronic kidney diseases." | 3.80 | Hydrogen sulfide alleviates diabetic nephropathy in a streptozotocin-induced diabetic rat model. ( Chen, J; Feng, Y; Zhan, Z; Zhou, X, 2014) |
| " The goal of the present study was to determine the therapeutic potential of a stable, long-acting H2S donor, diallyl trisulfide, in a model of pressure-overload heart failure and to assess the effects of chronic H2S therapy on myocardial vascular density and angiogenesis." | 3.79 | Hydrogen sulfide attenuates cardiac dysfunction after heart failure via induction of angiogenesis. ( Bhushan, S; Bir, SC; Calvert, JW; Kevil, CG; Kondo, K; Lefer, DJ; Murohara, T; Polhemus, D, 2013) |
| "To observe the level in plasma hydrogen sulfide (H2S) and the expression of cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CSE) (two key synthetases for endogenous H2S generation in the kidney) in obstructed kidney tissue among rats with tubulointerstitial fibrosis (TIF) induced by unilateral ureteral obstruction (UUO), and to explore the role of H2S in TIF." | 3.79 | [Change in plasma H2S level and therapeutic effect of H2S supplementation in tubulointerstitial fibrosis among rats with unilateral ureteral obstruction]. ( Han, ZM; Huang, Q; Liu, J; Zhao, DA, 2013) |
| "Fibrosis is defined as the pathological progress of excessive extracellular matrix (ECM), such as collagen, fibronectin, and elastin deposition, as the regenerative capacity of cells cannot satisfy the dynamic repair of chronic damage." | 2.72 | Gasotransmitters: Potential Therapeutic Molecules of Fibrotic Diseases. ( Cao, Y; Chen, Y; Jiang, F; Kong, G; Li, Y; Liu, L; Tang, M; Wang, Q; Yuan, S; Zhang, Q, 2021) |
| "Hydrogen sulfide (H2S) has antifibrotic activity in the kidneys, heart, lungs, and other organs." | 1.51 | Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway. ( Chen, Y; Jia, Q; Ma, SF; Mehmood, S; Wang, Y; Yang, R, 2019) |
| " Collectively, exercise restored bioavailability of hydrogen sulfide in the heart of aged rats, which partly explained the benefits of exercise against myocardial fibrosis of aged population." | 1.48 | Chronic aerobic exercise training alleviates myocardial fibrosis in aged rats through restoring bioavailability of hydrogen sulfide. ( Liu, HM; Liu, JD; Ma, N; Wang, XZ; Xia, T, 2018) |
| "Myocardial fibrosis is one of the most important pathological features of alcoholic cardiomyopathy (ACM)." | 1.46 | Hydrogen sulfide alleviates myocardial fibrosis in mice with alcoholic cardiomyopathy by downregulating autophagy. ( Li, Z; Liang, B; Liu, M; Liu, S; Long, J; Xiao, T; Yang, J, 2017) |
| "Myocardial fibrosis is the predominant pathological characteristic of diabetic myocardial damage." | 1.43 | Effects of hydrogen sulfide on myocardial fibrosis and PI3K/AKT1-regulated autophagy in diabetic rats. ( Li, F; Luo, J; Wu, Z; Xiao, T; Yang, J; Zeng, O, 2016) |
| "Hydrogen sulfide (H2S) has been found to be the third gaseous signaling molecule with anti‑ER stress effects." | 1.43 | Hydrogen sulfide exhibits cardioprotective effects by decreasing endoplasmic reticulum stress in a diabetic cardiomyopathy rat model. ( Li, F; Li, L; Li, Y; Luo, J; Wu, Z; Xiao, T; Yang, J; Zeng, O, 2016) |
| "Hydrogen sulfide has recently been found decreased in chronic kidney disease." | 1.40 | Hydrogen sulfide inhibits the renal fibrosis of obstructive nephropathy. ( Hu, LF; Li, Q; Liu, CF; Peng, H; Shen, HY; Shi, YB; Song, K; Wang, F; Zheng, HF, 2014) |
| "Hydrogen sulfide (H2S) has been recently found to be an endogenous signaling gasotransmitter." | 1.38 | Hydrogen sulfide attenuates cardiac hypertrophy and fibrosis induced by abdominal aortic coarctation in rats. ( Huang, J; Huang, X; Jin, H; Wang, D; Zheng, J, 2012) |
| "Cirrhosis was induced by surgical ligation of bile duct in rats." | 1.38 | The role of endogenous hydrogen sulfide in pathogenesis of chronotropic dysfunction in rats with cirrhosis. ( Babaei-Karamshahlou, M; Hajizadeh, S; Hooshmand, B; Mani, AR, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (2.17) | 29.6817 |
| 2010's | 35 (76.09) | 24.3611 |
| 2020's | 10 (21.74) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y | 3 |
| Yuan, S | 1 |
| Cao, Y | 1 |
| Kong, G | 1 |
| Jiang, F | 1 |
| Li, Y | 6 |
| Wang, Q | 2 |
| Tang, M | 1 |
| Zhang, Q | 1 |
| Liu, L | 1 |
| Zhang, Y | 2 |
| Gong, W | 1 |
| Xu, M | 1 |
| Zhang, S | 2 |
| Shen, J | 1 |
| Zhu, M | 1 |
| Wang, Y | 3 |
| Shi, J | 1 |
| Meng, G | 1 |
| Singh, M | 1 |
| Pushpakumar, S | 1 |
| Zheng, Y | 1 |
| Homme, RP | 1 |
| Smolenkova, I | 1 |
| Mokshagundam, SPL | 1 |
| Tyagi, SC | 1 |
| Li, Z | 5 |
| Xia, H | 1 |
| Sharp, TE | 1 |
| LaPenna, KB | 1 |
| Katsouda, A | 1 |
| Elrod, JW | 1 |
| Pfeilschifter, J | 1 |
| Beck, KF | 1 |
| Xu, S | 1 |
| Xian, M | 1 |
| Goodchild, TT | 1 |
| Papapetropoulos, A | 1 |
| Lefer, DJ | 2 |
| Hou, J | 1 |
| Huang, Y | 1 |
| Fu, L | 1 |
| Sun, M | 1 |
| Wang, L | 2 |
| Guo, R | 1 |
| Chen, L | 1 |
| Lv, C | 1 |
| Sun, HJ | 1 |
| Wu, ZY | 1 |
| Cao, L | 1 |
| Zhu, MY | 1 |
| Liu, TT | 1 |
| Guo, L | 1 |
| Lin, Y | 1 |
| Nie, XW | 1 |
| Bian, JS | 1 |
| Xing, QQ | 1 |
| Tu, JK | 1 |
| Tang, WB | 1 |
| Yuan, XN | 1 |
| Xie, YY | 1 |
| Wang, W | 1 |
| Peng, ZZ | 1 |
| Huang, L | 1 |
| Xu, H | 1 |
| Qin, J | 1 |
| Xiao, XC | 1 |
| Tao, LJ | 1 |
| Yuan, QJ | 1 |
| Tran, BH | 2 |
| Yu, Y | 1 |
| Chang, L | 1 |
| Tan, B | 1 |
| Jia, W | 1 |
| Xiong, Y | 1 |
| Dai, T | 1 |
| Zhong, R | 1 |
| Zhang, W | 2 |
| Le, VM | 1 |
| Rose, P | 1 |
| Wang, Z | 1 |
| Mao, Y | 1 |
| Zhu, YZ | 2 |
| Kang, SC | 1 |
| Sohn, EH | 1 |
| Lee, SR | 1 |
| Yang, R | 3 |
| Jia, Q | 3 |
| Mehmood, S | 2 |
| Xi, YX | 1 |
| Wen, X | 1 |
| Jiao, LJ | 1 |
| Wei, YX | 1 |
| Chang, GQ | 1 |
| Wu, R | 1 |
| Sun, FQ | 1 |
| Hao, JH | 1 |
| Li, HZ | 1 |
| Liu, M | 5 |
| Yi, J | 1 |
| Song, X | 1 |
| Zheng, X | 1 |
| Liu, D | 1 |
| Wang, S | 3 |
| Chu, C | 4 |
| Yang, J | 10 |
| Su, H | 2 |
| Liu, CH | 1 |
| Hu, HJ | 1 |
| Zhao, JB | 1 |
| Zou, T | 1 |
| Tang, YX | 1 |
| Li, L | 2 |
| Xiao, T | 8 |
| Li, F | 6 |
| Zeng, O | 5 |
| Liang, B | 3 |
| Han, SJ | 2 |
| Noh, MR | 1 |
| Jung, JM | 1 |
| Ishii, I | 1 |
| Yoo, J | 1 |
| Kim, JI | 2 |
| Park, KM | 2 |
| Long, J | 2 |
| Liu, S | 2 |
| Lin, S | 1 |
| Juriasingani, S | 1 |
| Sener, A | 1 |
| Jiang, Z | 2 |
| Qian, LL | 1 |
| Liu, XY | 1 |
| Chai, Q | 1 |
| Wang, RX | 1 |
| Ma, N | 1 |
| Liu, HM | 1 |
| Xia, T | 1 |
| Liu, JD | 1 |
| Wang, XZ | 1 |
| Wang, QY | 1 |
| Liu, XF | 1 |
| Ma, SF | 2 |
| Tang, F | 1 |
| Tan, W | 1 |
| Jiang, D | 1 |
| Yang, M | 1 |
| Polhemus, D | 1 |
| Kondo, K | 1 |
| Bhushan, S | 1 |
| Bir, SC | 1 |
| Kevil, CG | 1 |
| Murohara, T | 1 |
| Calvert, JW | 1 |
| Jung, KJ | 1 |
| Jang, HS | 1 |
| Park, JW | 1 |
| Huang, C | 1 |
| Kan, J | 1 |
| Liu, X | 1 |
| Ma, F | 1 |
| Zou, Y | 1 |
| Zhao, DA | 1 |
| Liu, J | 1 |
| Huang, Q | 1 |
| Han, ZM | 1 |
| Song, K | 2 |
| Wang, F | 1 |
| Li, Q | 2 |
| Shi, YB | 1 |
| Zheng, HF | 1 |
| Peng, H | 1 |
| Shen, HY | 1 |
| Liu, CF | 2 |
| Hu, LF | 2 |
| Zhou, X | 2 |
| Feng, Y | 1 |
| Zhan, Z | 1 |
| Chen, J | 2 |
| Zhao, L | 1 |
| Mao, J | 1 |
| Huang, J | 2 |
| Luo, J | 5 |
| Wu, Z | 4 |
| Zhang, J | 1 |
| Wu, ZX | 1 |
| Zhang, JJ | 1 |
| Yang, G | 1 |
| An, SS | 1 |
| Ji, Y | 1 |
| Pei, Y | 1 |
| Yin, XY | 1 |
| Lu, Y | 1 |
| Pan, C | 1 |
| Zhou, F | 1 |
| Yuan, Z | 1 |
| Wang, H | 1 |
| Cui, W | 1 |
| Zhang, G | 1 |
| Ying, R | 1 |
| Wang, XQ | 1 |
| Yang, Y | 1 |
| Gu, ZJ | 1 |
| Mai, JT | 1 |
| Qiu, Q | 1 |
| Chen, YX | 1 |
| Wang, JF | 1 |
| Younis, NN | 1 |
| Shaheen, MA | 1 |
| Mahmoud, MF | 1 |
| Sen, N | 1 |
| Renga, B | 1 |
| Mencarelli, A | 1 |
| Migliorati, M | 1 |
| Distrutti, E | 1 |
| Fiorucci, S | 1 |
| Wang, D | 1 |
| Zheng, J | 1 |
| Huang, X | 1 |
| Jin, H | 1 |
| Babaei-Karamshahlou, M | 1 |
| Hooshmand, B | 1 |
| Hajizadeh, S | 1 |
| Mani, AR | 1 |
| Fan, HN | 1 |
| Wang, HJ | 1 |
| Yang-Dan, CR | 1 |
| Ren, L | 1 |
| Wang, C | 1 |
| Li, YF | 1 |
| Deng, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Short-Term Endogenous Hydrogen Sulfide Upregulation For Vein Graft Disease[NCT05457881] | 226 participants (Anticipated) | Interventional | 2024-03-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for hydrogen sulfide and Cirrhosis
| Article | Year |
|---|---|
Gasotransmitters: Potential Therapeutic Molecules of Fibrotic Diseases.
Topics: Antioxidants; Fibrosis; Gasotransmitters; Heart Diseases; Humans; Hydrogen Sulfide; Liver Cirrhosis; | 2021 |
Hydrogen Sulfide: Recent Progression and Perspectives for the Treatment of Diabetic Nephropathy.
Topics: Animals; Diabetic Nephropathies; Drug Evaluation, Preclinical; Fibrosis; Humans; Hydrogen Sulfide; K | 2019 |
Involvement of hydrogen sulfide in the progression of renal fibrosis.
Topics: Animals; Disease Progression; Fibrosis; Humans; Hydrogen Sulfide; Kidney | 2019 |
Hydrogen Sulfide as a Potential Alternative for the Treatment of Myocardial Fibrosis.
Topics: Animals; Cardiomyopathies; Diabetes Mellitus; Fibrosis; Humans; Hydrogen Sulfide; Hypertension; Myoc | 2020 |
Is hydrogen sulfide a potential novel therapy to prevent renal damage during ureteral obstruction?
Topics: Animals; Carbon Monoxide; Disease Models, Animal; Fibrosis; Gasotransmitters; Humans; Hydrogen Sulfi | 2018 |
Hydrogen Sulfide in Diabetic Complications: Focus on Molecular Mechanisms.
Topics: Animals; Apoptosis; Diabetes Complications; Down-Regulation; Fibrosis; Humans; Hydrogen Sulfide; Inf | 2018 |
Hydrogen Sulfide: A Therapeutic Candidate for Fibrotic Disease?
Topics: Antifibrinolytic Agents; Fibrosis; Humans; Hydrogen Sulfide; Idiopathic Pulmonary Fibrosis; Liver Ci | 2015 |
Hydrogen Sulfide as a Potential Therapeutic Target in Fibrosis.
Topics: Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Fibrosis; Humans; Hydrogen Sulfide; Kidney; | 2015 |
Functional and Molecular Insights of Hydrogen Sulfide Signaling and Protein Sulfhydration.
Topics: Animals; Brain Injuries, Traumatic; Cell Cycle; Cell Differentiation; Cell Proliferation; Fibrosis; | 2017 |
37 other studies available for hydrogen sulfide and Cirrhosis
| Article | Year |
|---|---|
Necroptosis Inhibition by Hydrogen Sulfide Alleviated Hypoxia-Induced Cardiac Fibroblasts Proliferation via Sirtuin 3.
Topics: Animals; Animals, Newborn; Cell Proliferation; Fibroblasts; Fibrosis; Gasotransmitters; Heart; Hydro | 2021 |
Hydrogen sulfide mitigates skeletal muscle mitophagy-led tissue remodeling via epigenetic regulation of the gene writer and eraser function.
Topics: Animals; Epigenesis, Genetic; Fibrosis; Hydrogen Sulfide; Mice; Mitophagy; Muscle, Skeletal | 2022 |
Hydrogen Sulfide Modulates Endothelial-Mesenchymal Transition in Heart Failure.
Topics: Animals; Endothelial Cells; Endothelium, Vascular; Fibrosis; Heart Failure; Hydrogen Sulfide; Mice; | 2023 |
Evaluating the Effect of Hydrogen Sulfide in the Idiopathic Pulmonary Fibrosis Model with a Fluorescent Probe.
Topics: Animals; Fibrosis; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Sulfide; Idiopathic Pulmonary Fibr | 2023 |
A Novel Liposomal S-Propargyl-Cysteine: A Sustained Release of Hydrogen Sulfide Reducing Myocardial Fibrosis via TGF-β1/Smad Pathway.
Topics: Animals; Antioxidants; Cardiotonic Agents; Cystathionine gamma-Lyase; Cysteine; Disease Models, Anim | 2019 |
Protective effect of exogenous hydrogen sulfide on diaphragm muscle fibrosis in streptozotocin-induced diabetic rats.
Topics: Animals; Collagen; Cytokines; Diabetes Mellitus, Experimental; Diaphragm; Fibrosis; Hydrogen Sulfide | 2020 |
[Effects of exogenous H
Topics: Animals; Diabetes Mellitus, Experimental; Fibrosis; Hydrogen Sulfide; Liver Cirrhosis; Male; Matrix | 2020 |
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Topics: Animals; Apoptosis; Autophagy; Cell Line; Cystathionine gamma-Lyase; Disease Models, Animal; Endopla | 2020 |
H
Topics: Angiotensin II; Atrial Fibrillation; Base Sequence; Connective Tissue Growth Factor; Fibroblasts; Fi | 2021 |
Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats.
Topics: Animals; Autophagy; Autophagy-Related Proteins; Collagen Type IV; Diabetes Mellitus, Experimental; F | 2017 |
Hydrogen sulfide-producing cystathionine γ-lyase is critical in the progression of kidney fibrosis.
Topics: Actins; Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Disease Progression; Epithe | 2017 |
Hydrogen sulfide alleviates myocardial fibrosis in mice with alcoholic cardiomyopathy by downregulating autophagy.
Topics: Animals; Autophagy; Cardiomyopathy, Alcoholic; Down-Regulation; Fibrosis; Heart; Hydrogen Sulfide; M | 2017 |
Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway.
Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Endoplasmic Reticulu | 2018 |
Chronic aerobic exercise training alleviates myocardial fibrosis in aged rats through restoring bioavailability of hydrogen sulfide.
Topics: Aging; Animals; Chemokine CCL2; Endoplasmic Reticulum Stress; Fibrosis; Heart; Hydrogen Sulfide; Hyd | 2018 |
[Effects of hydrogen sulfide on renal fibrosis in diabetic rats and its mechanism].
Topics: Animals; Diabetes Mellitus, Experimental; Fibrosis; Hydrogen Sulfide; Male; Rats; Rats, Sprague-Dawl | 2018 |
H2S attenuates the myocardial fibrosis in diabetic rats through modulating PKC-ERK1/2MAPK signaling pathway.
Topics: Animals; Diabetes Mellitus, Experimental; Fibrosis; Hydrogen Sulfide; Male; MAP Kinase Signaling Sys | 2019 |
Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway.
Topics: Animals; Collagen; Diabetes Mellitus, Experimental; Fibrosis; Heart; Heart Diseases; Hydrogen Sulfid | 2019 |
Exogenous hydrogen sulfide prevents kidney damage following unilateral ureteral obstruction.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Fibrosis; Gasotransmitters; Hydrogen Sulfide; | 2014 |
Hydrogen sulfide attenuates cardiac dysfunction after heart failure via induction of angiogenesis.
Topics: Allyl Compounds; Angiostatins; Animals; Disease Models, Animal; Fibrosis; Heart Failure; Hydrogen Su | 2013 |
Involvement of hydrogen sulfide and homocysteine transsulfuration pathway in the progression of kidney fibrosis after ureteral obstruction.
Topics: Animals; Blood Pressure; Blotting, Western; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; | 2013 |
Cardioprotective effects of a novel hydrogen sulfide agent-controlled release formulation of S-propargyl-cysteine on heart failure rats and molecular mechanisms.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cysteine; Delayed-Action Preparations; Disease Models, Anima | 2013 |
[Change in plasma H2S level and therapeutic effect of H2S supplementation in tubulointerstitial fibrosis among rats with unilateral ureteral obstruction].
Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Dietary Supplements; Fibrosis; Hydr | 2013 |
Hydrogen sulfide inhibits the renal fibrosis of obstructive nephropathy.
Topics: Actins; Animals; Cell Line; Cell Proliferation; Collagen; Cystathionine beta-Synthase; Cystathionine | 2014 |
Hydrogen sulfide alleviates diabetic nephropathy in a streptozotocin-induced diabetic rat model.
Topics: Animals; Basement Membrane; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetic Nephropath | 2014 |
Antioxidant effects of hydrogen sulfide on left ventricular remodeling in smoking rats are mediated via PI3K/Akt-dependent activation of Nrf2.
Topics: Animals; Animals, Newborn; Antioxidants; Cells, Cultured; Cytoprotection; Disease Models, Animal; En | 2015 |
[Effect of hydrogen sulfide on myocardial fibrosis and expression of PKCα and HSP70 in diabetic rats].
Topics: Animals; Collagen Type III; Diabetes Mellitus, Experimental; Fibrosis; HSP70 Heat-Shock Proteins; Hy | 2015 |
[Effects of hydrogen sulfide on myocardial fibrosis and MAPK1/3 and MMP-8 expression in diabetic rats].
Topics: Animals; Collagen Type I; Diabetes Mellitus, Experimental; Fibrosis; Hydrogen Sulfide; Injections, I | 2015 |
Hydrogen Sulfide Signaling in Oxidative Stress and Aging Development.
Topics: Aging; Animals; Disease Models, Animal; Fibrosis; Humans; Hydrogen Sulfide; Oxidative Stress; Protec | 2015 |
Effects of hydrogen sulfide on myocardial fibrosis in diabetic rats: Changes in matrix metalloproteinases parameters.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Fibrosis; Heart; Hydrogen Sulfi | 2015 |
Hydrogen sulfide suppresses endoplasmic reticulum stress-induced endothelial-to-mesenchymal transition through Src pathway.
Topics: Down-Regulation; Endoplasmic Reticulum Stress; Epithelial-Mesenchymal Transition; Fibrosis; Human Um | 2016 |
Effects of hydrogen sulfide on myocardial fibrosis and PI3K/AKT1-regulated autophagy in diabetic rats.
Topics: Animals; Autophagy; Biomarkers; Collagen Type I; Collagen Type II; Cystathionine gamma-Lyase; Diabet | 2016 |
Hydrogen sulfide exhibits cardioprotective effects by decreasing endoplasmic reticulum stress in a diabetic cardiomyopathy rat model.
Topics: Animals; Blood Glucose; Body Weight; Cardiotonic Agents; Diabetic Cardiomyopathies; Disease Models, | 2016 |
Silymarin preconditioning protected insulin resistant rats from liver ischemia-reperfusion injury: role of endogenous H2S.
Topics: Animals; Antioxidants; Apoptosis; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Drug Evalu | 2016 |
Bile-acid-activated farnesoid X receptor regulates hydrogen sulfide production and hepatic microcirculation.
Topics: Adrenergic alpha-Agonists; Animals; Base Sequence; Bile Acids and Salts; Carbon Tetrachloride; Cell | 2009 |
Hydrogen sulfide attenuates cardiac hypertrophy and fibrosis induced by abdominal aortic coarctation in rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aortic Coarctation; Cardiomegaly; Connexin 43; Ena | 2012 |
The role of endogenous hydrogen sulfide in pathogenesis of chronotropic dysfunction in rats with cirrhosis.
Topics: Alkynes; Aminooxyacetic Acid; Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Fibro | 2012 |
Protective effects of hydrogen sulfide on oxidative stress and fibrosis in hepatic stellate cells.
Topics: Animals; Apoptosis; Calcium; Cell Line; Cell Proliferation; Collagen Type I; Cytoplasm; Disease Mode | 2013 |