hydrogen sulfide has been researched along with Cardiomegaly in 13 studies
Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Specific drugs for the treatment of cardiac hypertrophy are still in urgent need." | 5.72 | Identification of a Hydrogen-Sulfide-Releasing Isochroman-4-One Hybrid as a Cardioprotective Candidate for the Treatment of Cardiac Hypertrophy. ( Liu, Y; Ma, F; Wang, Y; Wu, H; Xu, S, 2022) |
| "Hydrogen sulfide (H2S) has been recently found to be an endogenous signaling gasotransmitter." | 5.38 | Hydrogen sulfide attenuates cardiac hypertrophy and fibrosis induced by abdominal aortic coarctation in rats. ( Huang, J; Huang, X; Jin, H; Wang, D; Zheng, J, 2012) |
| "Hydrogen sulfide (H(2)S) is an endogenous signaling molecule with potent cytoprotective effects." | 5.36 | Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice. ( Calvert, JW; Elrod, JW; Elston, M; Gundewar, S; Jha, S; Lefer, DJ; Nicholson, CK; Ramachandran, A, 2010) |
| "Dietary methionine restriction (MR) has been reported to extend lifespan, reduce obesity and decrease oxidative damage to mtDNA in the heart of rats, and increase endogenous hydrogen sulfide (H2S) production in the liver and blood." | 3.96 | Dietary methionine restriction improves the impairment of cardiac function in middle-aged obese mice. ( Feng, C; Ge, Y; Han, L; Jiang, Y; Le, G; Li, B; Shi, Y; Wu, G; Yang, Y, 2020) |
| "The aim of the study was to evaluate the clinical efficacy of hydrogen sulfide (H2S) treatment on the endothelin-induced cardiac hypertrophy." | 3.80 | Hydrogen sulfide endothelin-induced myocardial hypertrophy in rats and the mechanism involved. ( Li, Z; Liu, Z; Wang, Q; Wang, Y; Yang, F; Yu, H, 2014) |
| "Specific drugs for the treatment of cardiac hypertrophy are still in urgent need." | 1.72 | Identification of a Hydrogen-Sulfide-Releasing Isochroman-4-One Hybrid as a Cardioprotective Candidate for the Treatment of Cardiac Hypertrophy. ( Liu, Y; Ma, F; Wang, Y; Wu, H; Xu, S, 2022) |
| "Cardiac hypertrophy is a critical component of phenotype in the failing heart." | 1.46 | Protective effect of hydrogen sulphide against myocardial hypertrophy in mice. ( Chen, G; Hu, L; Jiang, R; Lin, C; Ping, J; Shan, J; Shao, M; Tian, H; Wang, L; Zhuo, C, 2017) |
| "Hydrogen sulfide (H2S) is a gasotransmitter that regulates multiple cardiovascular functions." | 1.43 | Hydrogen Sulfide Regulates Krüppel-Like Factor 5 Transcription Activity via Specificity Protein 1 S-Sulfhydration at Cys664 to Prevent Myocardial Hypertrophy. ( Ferro, A; Gu, Y; Han, Y; Ji, Y; Liu, J; Ma, Y; Meng, G; Moore, PK; Park, CM; Tang, X; Wang, H; Wang, R; Wang, X; Xian, M; Xiao, Y; Xie, L; Yu, Y; Zhang, Z, 2016) |
| "Hydrogen sulfide (H2S) is an endogenously produced gasotransmitter with cardioprotective properties." | 1.42 | Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats. ( de Boer, RA; Frenay, AR; Hillebrands, JL; Leuvenink, HG; Pasch, A; Snijder, PM; van Goor, H, 2015) |
| "Hydrogen sulfide (H2S) has been recently found to be an endogenous signaling gasotransmitter." | 1.38 | Hydrogen sulfide attenuates cardiac hypertrophy and fibrosis induced by abdominal aortic coarctation in rats. ( Huang, J; Huang, X; Jin, H; Wang, D; Zheng, J, 2012) |
| "Hydrogen sulfide (H(2)S) is an endogenous signaling molecule with potent cytoprotective effects." | 1.36 | Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice. ( Calvert, JW; Elrod, JW; Elston, M; Gundewar, S; Jha, S; Lefer, DJ; Nicholson, CK; Ramachandran, A, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 11 (84.62) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 2 |
| Liu, Y | 1 |
| Wu, H | 1 |
| Xu, S | 1 |
| Ma, F | 1 |
| Han, L | 1 |
| Wu, G | 1 |
| Feng, C | 1 |
| Yang, Y | 1 |
| Li, B | 1 |
| Ge, Y | 1 |
| Jiang, Y | 1 |
| Shi, Y | 1 |
| Le, G | 1 |
| Shao, M | 1 |
| Zhuo, C | 1 |
| Jiang, R | 1 |
| Chen, G | 1 |
| Shan, J | 1 |
| Ping, J | 1 |
| Tian, H | 1 |
| Wang, L | 2 |
| Lin, C | 1 |
| Hu, L | 1 |
| Meng, G | 2 |
| Liu, J | 3 |
| Liu, S | 1 |
| Song, Q | 1 |
| Liu, L | 1 |
| Xie, L | 2 |
| Han, Y | 2 |
| Ji, Y | 2 |
| Wu, Y | 1 |
| Guo, YY | 1 |
| Zhang, YY | 1 |
| Zhang, Y | 1 |
| Lu, F | 1 |
| Xing, J | 1 |
| Zhang, X | 1 |
| Dong, S | 1 |
| Zhao, Y | 1 |
| Li, H | 1 |
| Yang, F | 2 |
| Xu, C | 1 |
| Zhang, W | 1 |
| Snijder, PM | 1 |
| Frenay, AR | 1 |
| de Boer, RA | 1 |
| Pasch, A | 1 |
| Hillebrands, JL | 1 |
| Leuvenink, HG | 1 |
| van Goor, H | 1 |
| Liu, Z | 1 |
| Li, Z | 1 |
| Yu, H | 1 |
| Wang, Q | 1 |
| Xiao, Y | 1 |
| Ma, Y | 1 |
| Tang, X | 1 |
| Gu, Y | 1 |
| Yu, Y | 1 |
| Park, CM | 1 |
| Xian, M | 1 |
| Wang, X | 1 |
| Ferro, A | 1 |
| Wang, R | 1 |
| Moore, PK | 1 |
| Zhang, Z | 1 |
| Wang, H | 1 |
| Calvert, JW | 1 |
| Elston, M | 1 |
| Nicholson, CK | 1 |
| Gundewar, S | 1 |
| Jha, S | 1 |
| Elrod, JW | 1 |
| Ramachandran, A | 1 |
| Lefer, DJ | 1 |
| Givvimani, S | 1 |
| Munjal, C | 1 |
| Gargoum, R | 1 |
| Sen, U | 1 |
| Tyagi, N | 1 |
| Vacek, JC | 1 |
| Tyagi, SC | 1 |
| Hao, DD | 1 |
| Zhang, JS | 1 |
| Zhu, YC | 1 |
| Huang, J | 1 |
| Wang, D | 1 |
| Zheng, J | 1 |
| Huang, X | 1 |
| Jin, H | 1 |
13 other studies available for hydrogen sulfide and Cardiomegaly
| Article | Year |
|---|---|
Identification of a Hydrogen-Sulfide-Releasing Isochroman-4-One Hybrid as a Cardioprotective Candidate for the Treatment of Cardiac Hypertrophy.
Topics: Cardiomegaly; Heart; Humans; Hydrogen; Hydrogen Sulfide; Myocytes, Cardiac; Sulfides | 2022 |
Dietary methionine restriction improves the impairment of cardiac function in middle-aged obese mice.
Topics: Animals; Body Weight; Cardiomegaly; Diet; Energy Metabolism; Homocysteine; Hydrogen Sulfide; Male; M | 2020 |
Protective effect of hydrogen sulphide against myocardial hypertrophy in mice.
Topics: Animals; Aorta; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Echocardiography; Heart Failu | 2017 |
Hydrogen sulfide pretreatment improves mitochondrial function in myocardial hypertrophy via a SIRT3-dependent manner.
Topics: Angiotensin II; Animals; Cardiomegaly; Hydrogen Sulfide; Male; Membrane Potential, Mitochondrial; Mi | 2018 |
[Effects of hydrogen sulfide (H
Topics: Animals; Calcineurin; Cardiomegaly; Cells, Cultured; Cystathionine gamma-Lyase; Hydrogen Sulfide; Mi | 2018 |
Exogenous hydrogen sulfide prevents cardiomyocyte apoptosis from cardiac hypertrophy induced by isoproterenol.
Topics: Animals; Animals, Newborn; Apoptosis; Benzimidazoles; Carbocyanines; Cardiomegaly; Cardiotonic Agent | 2013 |
Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Models, Anim | 2015 |
Hydrogen sulfide endothelin-induced myocardial hypertrophy in rats and the mechanism involved.
Topics: Animals; Cardiomegaly; Collagen; Disease Models, Animal; Endothelins; Heart Ventricles; Hydrogen Sul | 2014 |
Hydrogen Sulfide Regulates Krüppel-Like Factor 5 Transcription Activity via Specificity Protein 1 S-Sulfhydration at Cys664 to Prevent Myocardial Hypertrophy.
Topics: Angiotensin II; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Case-Control Stu | 2016 |
Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice.
Topics: Animals; Body Weight; Cardiomegaly; Cystathionine gamma-Lyase; Gene Expression Regulation, Enzymolog | 2010 |
Hydrogen sulfide mitigates transition from compensatory hypertrophy to heart failure.
Topics: Analysis of Variance; Animals; Blotting, Western; Cardiomegaly; Disease Progression; Echocardiograph | 2011 |
Hydrogen sulphide inhibits cardiomyocyte hypertrophy by up-regulating miR-133a.
Topics: Animals; Cardiomegaly; Cell Line; Hydrogen Sulfide; Hypertrophy; MicroRNAs; Myocytes, Cardiac; Natri | 2011 |
Hydrogen sulfide attenuates cardiac hypertrophy and fibrosis induced by abdominal aortic coarctation in rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aortic Coarctation; Cardiomegaly; Connexin 43; Ena | 2012 |