Page last updated: 2024-10-17

hydrogen sulfide and Cardiomegaly

hydrogen sulfide has been researched along with Cardiomegaly in 13 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.

Research Excerpts

ExcerptRelevanceReference
"Specific drugs for the treatment of cardiac hypertrophy are still in urgent need."5.72Identification of a Hydrogen-Sulfide-Releasing Isochroman-4-One Hybrid as a Cardioprotective Candidate for the Treatment of Cardiac Hypertrophy. ( Liu, Y; Ma, F; Wang, Y; Wu, H; Xu, S, 2022)
"Hydrogen sulfide (H2S) has been recently found to be an endogenous signaling gasotransmitter."5.38Hydrogen sulfide attenuates cardiac hypertrophy and fibrosis induced by abdominal aortic coarctation in rats. ( Huang, J; Huang, X; Jin, H; Wang, D; Zheng, J, 2012)
"Hydrogen sulfide (H(2)S) is an endogenous signaling molecule with potent cytoprotective effects."5.36Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice. ( Calvert, JW; Elrod, JW; Elston, M; Gundewar, S; Jha, S; Lefer, DJ; Nicholson, CK; Ramachandran, A, 2010)
"Dietary methionine restriction (MR) has been reported to extend lifespan, reduce obesity and decrease oxidative damage to mtDNA in the heart of rats, and increase endogenous hydrogen sulfide (H2S) production in the liver and blood."3.96Dietary methionine restriction improves the impairment of cardiac function in middle-aged obese mice. ( Feng, C; Ge, Y; Han, L; Jiang, Y; Le, G; Li, B; Shi, Y; Wu, G; Yang, Y, 2020)
"The aim of the study was to evaluate the clinical efficacy of hydrogen sulfide (H2S) treatment on the endothelin-induced cardiac hypertrophy."3.80Hydrogen sulfide endothelin-induced myocardial hypertrophy in rats and the mechanism involved. ( Li, Z; Liu, Z; Wang, Q; Wang, Y; Yang, F; Yu, H, 2014)
"Specific drugs for the treatment of cardiac hypertrophy are still in urgent need."1.72Identification of a Hydrogen-Sulfide-Releasing Isochroman-4-One Hybrid as a Cardioprotective Candidate for the Treatment of Cardiac Hypertrophy. ( Liu, Y; Ma, F; Wang, Y; Wu, H; Xu, S, 2022)
"Cardiac hypertrophy is a critical component of phenotype in the failing heart."1.46Protective effect of hydrogen sulphide against myocardial hypertrophy in mice. ( Chen, G; Hu, L; Jiang, R; Lin, C; Ping, J; Shan, J; Shao, M; Tian, H; Wang, L; Zhuo, C, 2017)
"Hydrogen sulfide (H2S) is a gasotransmitter that regulates multiple cardiovascular functions."1.43Hydrogen Sulfide Regulates Krüppel-Like Factor 5 Transcription Activity via Specificity Protein 1 S-Sulfhydration at Cys664 to Prevent Myocardial Hypertrophy. ( Ferro, A; Gu, Y; Han, Y; Ji, Y; Liu, J; Ma, Y; Meng, G; Moore, PK; Park, CM; Tang, X; Wang, H; Wang, R; Wang, X; Xian, M; Xiao, Y; Xie, L; Yu, Y; Zhang, Z, 2016)
"Hydrogen sulfide (H2S) is an endogenously produced gasotransmitter with cardioprotective properties."1.42Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats. ( de Boer, RA; Frenay, AR; Hillebrands, JL; Leuvenink, HG; Pasch, A; Snijder, PM; van Goor, H, 2015)
"Hydrogen sulfide (H2S) has been recently found to be an endogenous signaling gasotransmitter."1.38Hydrogen sulfide attenuates cardiac hypertrophy and fibrosis induced by abdominal aortic coarctation in rats. ( Huang, J; Huang, X; Jin, H; Wang, D; Zheng, J, 2012)
"Hydrogen sulfide (H(2)S) is an endogenous signaling molecule with potent cytoprotective effects."1.36Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice. ( Calvert, JW; Elrod, JW; Elston, M; Gundewar, S; Jha, S; Lefer, DJ; Nicholson, CK; Ramachandran, A, 2010)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's11 (84.62)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Wang, Y2
Liu, Y1
Wu, H1
Xu, S1
Ma, F1
Han, L1
Wu, G1
Feng, C1
Yang, Y1
Li, B1
Ge, Y1
Jiang, Y1
Shi, Y1
Le, G1
Shao, M1
Zhuo, C1
Jiang, R1
Chen, G1
Shan, J1
Ping, J1
Tian, H1
Wang, L2
Lin, C1
Hu, L1
Meng, G2
Liu, J3
Liu, S1
Song, Q1
Liu, L1
Xie, L2
Han, Y2
Ji, Y2
Wu, Y1
Guo, YY1
Zhang, YY1
Zhang, Y1
Lu, F1
Xing, J1
Zhang, X1
Dong, S1
Zhao, Y1
Li, H1
Yang, F2
Xu, C1
Zhang, W1
Snijder, PM1
Frenay, AR1
de Boer, RA1
Pasch, A1
Hillebrands, JL1
Leuvenink, HG1
van Goor, H1
Liu, Z1
Li, Z1
Yu, H1
Wang, Q1
Xiao, Y1
Ma, Y1
Tang, X1
Gu, Y1
Yu, Y1
Park, CM1
Xian, M1
Wang, X1
Ferro, A1
Wang, R1
Moore, PK1
Zhang, Z1
Wang, H1
Calvert, JW1
Elston, M1
Nicholson, CK1
Gundewar, S1
Jha, S1
Elrod, JW1
Ramachandran, A1
Lefer, DJ1
Givvimani, S1
Munjal, C1
Gargoum, R1
Sen, U1
Tyagi, N1
Vacek, JC1
Tyagi, SC1
Hao, DD1
Zhang, JS1
Zhu, YC1
Huang, J1
Wang, D1
Zheng, J1
Huang, X1
Jin, H1

Other Studies

13 other studies available for hydrogen sulfide and Cardiomegaly

ArticleYear
Identification of a Hydrogen-Sulfide-Releasing Isochroman-4-One Hybrid as a Cardioprotective Candidate for the Treatment of Cardiac Hypertrophy.
    Molecules (Basel, Switzerland), 2022, Jun-27, Volume: 27, Issue:13

    Topics: Cardiomegaly; Heart; Humans; Hydrogen; Hydrogen Sulfide; Myocytes, Cardiac; Sulfides

2022
Dietary methionine restriction improves the impairment of cardiac function in middle-aged obese mice.
    Food & function, 2020, Feb-26, Volume: 11, Issue:2

    Topics: Animals; Body Weight; Cardiomegaly; Diet; Energy Metabolism; Homocysteine; Hydrogen Sulfide; Male; M

2020
Protective effect of hydrogen sulphide against myocardial hypertrophy in mice.
    Oncotarget, 2017, Apr-04, Volume: 8, Issue:14

    Topics: Animals; Aorta; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Echocardiography; Heart Failu

2017
Hydrogen sulfide pretreatment improves mitochondrial function in myocardial hypertrophy via a SIRT3-dependent manner.
    British journal of pharmacology, 2018, Volume: 175, Issue:8

    Topics: Angiotensin II; Animals; Cardiomegaly; Hydrogen Sulfide; Male; Membrane Potential, Mitochondrial; Mi

2018
[Effects of hydrogen sulfide (H
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2018, Jan-08, Volume: 34, Issue:1

    Topics: Animals; Calcineurin; Cardiomegaly; Cells, Cultured; Cystathionine gamma-Lyase; Hydrogen Sulfide; Mi

2018
Exogenous hydrogen sulfide prevents cardiomyocyte apoptosis from cardiac hypertrophy induced by isoproterenol.
    Molecular and cellular biochemistry, 2013, Volume: 381, Issue:1-2

    Topics: Animals; Animals, Newborn; Apoptosis; Benzimidazoles; Carbocyanines; Cardiomegaly; Cardiotonic Agent

2013
Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats.
    British journal of pharmacology, 2015, Volume: 172, Issue:6

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Models, Anim

2015
Hydrogen sulfide endothelin-induced myocardial hypertrophy in rats and the mechanism involved.
    Cell biochemistry and biophysics, 2014, Volume: 70, Issue:3

    Topics: Animals; Cardiomegaly; Collagen; Disease Models, Animal; Endothelins; Heart Ventricles; Hydrogen Sul

2014
Hydrogen Sulfide Regulates Krüppel-Like Factor 5 Transcription Activity via Specificity Protein 1 S-Sulfhydration at Cys664 to Prevent Myocardial Hypertrophy.
    Journal of the American Heart Association, 2016, 09-16, Volume: 5, Issue:9

    Topics: Angiotensin II; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Case-Control Stu

2016
Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice.
    Circulation, 2010, Jul-06, Volume: 122, Issue:1

    Topics: Animals; Body Weight; Cardiomegaly; Cystathionine gamma-Lyase; Gene Expression Regulation, Enzymolog

2010
Hydrogen sulfide mitigates transition from compensatory hypertrophy to heart failure.
    Journal of applied physiology (Bethesda, Md. : 1985), 2011, Volume: 110, Issue:4

    Topics: Analysis of Variance; Animals; Blotting, Western; Cardiomegaly; Disease Progression; Echocardiograph

2011
Hydrogen sulphide inhibits cardiomyocyte hypertrophy by up-regulating miR-133a.
    Biochemical and biophysical research communications, 2011, Sep-23, Volume: 413, Issue:2

    Topics: Animals; Cardiomegaly; Cell Line; Hydrogen Sulfide; Hypertrophy; MicroRNAs; Myocytes, Cardiac; Natri

2011
Hydrogen sulfide attenuates cardiac hypertrophy and fibrosis induced by abdominal aortic coarctation in rats.
    Molecular medicine reports, 2012, Volume: 5, Issue:4

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aortic Coarctation; Cardiomegaly; Connexin 43; Ena

2012