Page last updated: 2024-10-17

hydrogen sulfide and Cardiac Diseases

hydrogen sulfide has been researched along with Cardiac Diseases in 16 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Research Excerpts

ExcerptRelevanceReference
"Cirrhosis was induced by surgical ligation of bile duct in rats."5.38The role of endogenous hydrogen sulfide in pathogenesis of chronotropic dysfunction in rats with cirrhosis. ( Babaei-Karamshahlou, M; Hajizadeh, S; Hooshmand, B; Mani, AR, 2012)
"Fibrosis is defined as the pathological progress of excessive extracellular matrix (ECM), such as collagen, fibronectin, and elastin deposition, as the regenerative capacity of cells cannot satisfy the dynamic repair of chronic damage."2.72Gasotransmitters: Potential Therapeutic Molecules of Fibrotic Diseases. ( Cao, Y; Chen, Y; Jiang, F; Kong, G; Li, Y; Liu, L; Tang, M; Wang, Q; Yuan, S; Zhang, Q, 2021)
"Hydrogen sulfide (H2S) has been long recognized as a highly poisonous gas that is rapidly lethal in intoxicating dosage."2.52Hydrogen sulfide and cardioprotection--Mechanistic insights and clinical translatability. ( Salloum, FN, 2015)
"Hydrogen sulfide (H2S) has antifibrotic activity in the kidneys, heart, lungs, and other organs."1.51Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway. ( Chen, Y; Jia, Q; Ma, SF; Mehmood, S; Wang, Y; Yang, R, 2019)
"Cirrhosis was induced by surgical ligation of bile duct in rats."1.38The role of endogenous hydrogen sulfide in pathogenesis of chronotropic dysfunction in rats with cirrhosis. ( Babaei-Karamshahlou, M; Hajizadeh, S; Hooshmand, B; Mani, AR, 2012)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (25.00)29.6817
2010's9 (56.25)24.3611
2020's3 (18.75)2.80

Authors

AuthorsStudies
Chen, Y2
Yuan, S1
Cao, Y1
Kong, G1
Jiang, F1
Li, Y1
Wang, Q2
Tang, M1
Zhang, Q1
Liu, L1
Bai, L1
Dai, J1
Xia, Y1
He, K1
Xue, H1
Guo, Q1
Tian, D1
Xiao, L1
Zhang, X1
Teng, X1
Wu, Y1
Jin, S1
Merz, T1
Denoix, N1
Wigger, D1
Waller, C1
Wepler, M1
Vettorazzi, S1
Tuckermann, J1
Radermacher, P1
McCook, O1
Kuang, Q1
Xue, N1
Chen, J1
Shen, Z2
Cui, X1
Fang, Y1
Ding, X1
Yang, R1
Jia, Q1
Ma, SF1
Wang, Y1
Mehmood, S1
Salloum, FN1
Shen, Y1
Luo, S1
Guo, W1
Zhu, YZ1
Liu, MH1
Lin, XL1
Zhang, Y1
He, J1
Tan, TP1
Wu, SJ1
Liu, J1
Tian, W1
Chen, L1
Yu, S1
Li, J1
Yuan, C1
Finnbjornsdottir, RG1
Carlsen, HK1
Thorsteinsson, T1
Oudin, A1
Lund, SH1
Gislason, T1
Rafnsson, V1
Yong, QC2
Lee, SW1
Foo, CS1
Neo, KL2
Chen, X1
Bian, JS2
Liao, F1
Zheng, Y1
Geng, B2
Louis, XL1
Murphy, R1
Thandapilly, SJ1
Yu, L1
Netticadan, T1
Babaei-Karamshahlou, M1
Hooshmand, B1
Hajizadeh, S1
Mani, AR1
Llorca, J1
Salas, A1
Prieto-Salceda, D1
Chinchon-Bengoechea, V1
Delgado-Rodríguez, M1
Hu, LF1
Pan, TT1
Chang, L1
Yu, F1
Zhao, J1
Jiang, H1
Du, J1
Tang, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Plasma Measurement of Hydrogen Sulfide, Nitric Oxide and Stress Hyperglycemia in Acute Myocardial Infarction[NCT03829605]50 participants (Anticipated)Observational2019-02-15Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for hydrogen sulfide and Cardiac Diseases

ArticleYear
Gasotransmitters: Potential Therapeutic Molecules of Fibrotic Diseases.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Antioxidants; Fibrosis; Gasotransmitters; Heart Diseases; Humans; Hydrogen Sulfide; Liver Cirrhosis;

2021
Hydrogen sulfide and cardioprotection--Mechanistic insights and clinical translatability.
    Pharmacology & therapeutics, 2015, Volume: 152

    Topics: Animals; Cardiotonic Agents; Heart; Heart Diseases; Humans; Hydrogen Sulfide; Oxidative Stress; Sign

2015
The Cardioprotective Effects of Hydrogen Sulfide in Heart Diseases: From Molecular Mechanisms to Therapeutic Potential.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Animals; Heart Diseases; Heart Failure; Hydrogen Sulfide; Mitochondria; Nitric Oxide; Protective Age

2015
[Hydrogen sulfide--a novel cardiac disease protector].
    Sheng li ke xue jin zhan [Progress in physiology], 2012, Volume: 43, Issue:2

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Heart Diseases; Humans; Hydrogen Sulfid

2012

Other Studies

12 other studies available for hydrogen sulfide and Cardiac Diseases

ArticleYear
Hydrogen Sulfide Ameliorated High Choline-Induced Cardiac Dysfunction by Inhibiting cGAS-STING-NLRP3 Inflammasome Pathway.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Animals; Caspase 1; Choline; Cystathionine gamma-Lyase; Heart Diseases; Hydrogen Sulfide; Inflammaso

2022
The Role of Glucocorticoid Receptor and Oxytocin Receptor in the Septic Heart in a Clinically Relevant, Resuscitated Porcine Model With Underlying Atherosclerosis.
    Frontiers in endocrinology, 2020, Volume: 11

    Topics: Animals; Atherosclerosis; Cystathionine gamma-Lyase; Disease Models, Animal; Gene Expression Regulat

2020
Low Plasma Hydrogen Sulfide Is Associated with Impaired Renal Function and Cardiac Dysfunction.
    American journal of nephrology, 2018, Volume: 47, Issue:5

    Topics: Adult; Aged; Biomarkers; Disease Progression; Echocardiography; Female; Glomerular Filtration Rate;

2018
Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway.
    International journal of molecular medicine, 2019, Volume: 44, Issue:2

    Topics: Animals; Collagen; Diabetes Mellitus, Experimental; Fibrosis; Heart; Heart Diseases; Hydrogen Sulfid

2019
Hydrogen sulfide attenuates doxorubicin-induced cardiotoxicity by inhibiting reactive oxygen species-activated extracellular signal-regulated kinase 1/2 in H9c2 cardiac myocytes.
    Molecular medicine reports, 2015, Volume: 12, Issue:5

    Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Cardiotonic Agents; Cell Line; Cystathionine g

2015
Association between Daily Hydrogen Sulfide Exposure and Incidence of Emergency Hospital Visits: A Population-Based Study.
    PloS one, 2016, Volume: 11, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Emergency Service, Hospital; Environmental Exposure; Female; Heart D

2016
Endogenous hydrogen sulphide mediates the cardioprotection induced by ischemic postconditioning.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:3

    Topics: Alkynes; Animals; Antibodies, Blocking; Blood Pressure; Chromones; Dimethyl Sulfoxide; Electrocardio

2008
Garlic extracts prevent oxidative stress, hypertrophy and apoptosis in cardiomyocytes: a role for nitric oxide and hydrogen sulfide.
    BMC complementary and alternative medicine, 2012, Aug-29, Volume: 12

    Topics: Animals; Antioxidants; Apoptosis; Cysteine; Disulfides; Garlic; Heart; Heart Diseases; Hydrogen Sulf

2012
The role of endogenous hydrogen sulfide in pathogenesis of chronotropic dysfunction in rats with cirrhosis.
    European journal of pharmacology, 2012, Dec-05, Volume: 696, Issue:1-3

    Topics: Alkynes; Aminooxyacetic Acid; Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Fibro

2012
Nitrogen dioxide increases cardiorespiratory admissions in Torrelavega (Spain).
    Journal of environmental health, 2005, Volume: 68, Issue:2

    Topics: Air Pollutants; Heart Diseases; Hospitalization; Humans; Hydrogen Sulfide; Nitrogen Dioxide; Nitroge

2005
Cyclooxygenase-2 mediates the delayed cardioprotection induced by hydrogen sulfide preconditioning in isolated rat cardiomyocytes.
    Pflugers Archiv : European journal of physiology, 2008, Volume: 455, Issue:6

    Topics: Air Pollutants; Animals; Blotting, Western; Cell Separation; Cell Survival; Cyclooxygenase 2; Cycloo

2008
Hydrogen sulfide inhibits myocardial injury induced by homocysteine in rats.
    Amino acids, 2008, Volume: 34, Issue:4

    Topics: Animals; Cystathionine gamma-Lyase; Disease Models, Animal; Electron Transport Complex IV; Endoplasm

2008