Page last updated: 2024-10-17

hydrogen sulfide and Asthma

hydrogen sulfide has been researched along with Asthma in 27 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Results have been conflicting whether long-term ambient hydrogen sulfide (H2S) affects lung function or is a risk factor for asthma or chronic obstructive pulmonary disease (COPD)."7.81Investigation of hydrogen sulfide exposure and lung function, asthma and chronic obstructive pulmonary disease in a geothermal area of New Zealand. ( Balmes, JR; Bates, MN; Crane, J; Garrett, N, 2015)
"Endogenous hydrogen sulfide (H2 S) may be a biomarker of asthma severity and activity."7.80Correlation between levels of exhaled hydrogen sulfide and airway inflammatory phenotype in patients with chronic persistent asthma. ( Chen, Y; Wang, X; Yao, W; Zhang, J, 2014)
"Whether long-term, low-level hydrogen sulfide (H2S) gas is a cause of health effects, including asthma, is uncertain."7.79Associations of ambient hydrogen sulfide exposure with self-reported asthma and asthma symptoms. ( Balmes, JR; Bates, MN; Crane, J; Garrett, N, 2013)
"To investigate plasma hydrogen sulfide (H₂S) levels and cystathionine-gamma- lyase (CSE) and cystathionine-beta-synthase (CBS) mRNA expression in the lung tissues in asthmatic rats and to explore the roles of endogenous H₂S, CSE and CBS system in the pathogenesis of asthma."7.76[Regulative mechanism of budesonide on endogenous hydrogen sulfide, cystathionine-gamma-lyase and cystathionine-beta-synthase system in asthmatic rats]. ( Jin, XH; Li, SB; Tong, XS; Wang, XX; Ye, H, 2010)
"Endogenous hydrogen sulfide (H(2)S) is hypothesized to have an important role in systemic inflammation."7.75Endogenous hydrogen sulfide reduces airway inflammation and remodeling in a rat model of asthma. ( Chen, YH; Geng, B; Qi, YF; Tang, CS; Wang, PP; Wu, R; Yao, WZ, 2009)
"To investigate the role of endogenous hydrogen sulfide (H2S) in patients with asthma."7.74[Plasma level of endogenous hydrogen sulfide in patients with acute asthma]. ( Chen, YH; Geng, B; Tang, CS; Wu, R; Yao, WZ, 2008)
"To study the changes of endogenous hydrogen sulfide (H(2)S) and the effect of exogenously applied H(2)S on ovalbumin-induced acute asthma."7.74[The regulatory effect of endogenous hydrogen sulfide on acute asthma]. ( Chen, YH; Geng, B; Lu, M; Tang, CS; Wu, R; Yao, WZ, 2007)
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"Allergic asthma was induced with ovalbumin in wild-type (WT) and CSE knock-out (KO) mice at young and old ages."3.85Age-Dependent Allergic Asthma Development and Cystathionine Gamma-Lyase Deficiency. ( Fu, M; Ju, Y; Qian, Z; Shuang, T; Wang, P; Wang, R; Wu, L, 2017)
"Results have been conflicting whether long-term ambient hydrogen sulfide (H2S) affects lung function or is a risk factor for asthma or chronic obstructive pulmonary disease (COPD)."3.81Investigation of hydrogen sulfide exposure and lung function, asthma and chronic obstructive pulmonary disease in a geothermal area of New Zealand. ( Balmes, JR; Bates, MN; Crane, J; Garrett, N, 2015)
"Endogenous hydrogen sulfide (H2 S) may be a biomarker of asthma severity and activity."3.80Correlation between levels of exhaled hydrogen sulfide and airway inflammatory phenotype in patients with chronic persistent asthma. ( Chen, Y; Wang, X; Yao, W; Zhang, J, 2014)
"Whether long-term, low-level hydrogen sulfide (H2S) gas is a cause of health effects, including asthma, is uncertain."3.79Associations of ambient hydrogen sulfide exposure with self-reported asthma and asthma symptoms. ( Balmes, JR; Bates, MN; Crane, J; Garrett, N, 2013)
"To investigate plasma hydrogen sulfide (H₂S) levels and cystathionine-gamma- lyase (CSE) and cystathionine-beta-synthase (CBS) mRNA expression in the lung tissues in asthmatic rats and to explore the roles of endogenous H₂S, CSE and CBS system in the pathogenesis of asthma."3.76[Regulative mechanism of budesonide on endogenous hydrogen sulfide, cystathionine-gamma-lyase and cystathionine-beta-synthase system in asthmatic rats]. ( Jin, XH; Li, SB; Tong, XS; Wang, XX; Ye, H, 2010)
"Endogenous hydrogen sulfide (H(2)S) is hypothesized to have an important role in systemic inflammation."3.75Endogenous hydrogen sulfide reduces airway inflammation and remodeling in a rat model of asthma. ( Chen, YH; Geng, B; Qi, YF; Tang, CS; Wang, PP; Wu, R; Yao, WZ, 2009)
"To investigate the role of endogenous hydrogen sulfide (H2S) in patients with asthma."3.74[Plasma level of endogenous hydrogen sulfide in patients with acute asthma]. ( Chen, YH; Geng, B; Tang, CS; Wu, R; Yao, WZ, 2008)
"To study the changes of endogenous hydrogen sulfide (H(2)S) and the effect of exogenously applied H(2)S on ovalbumin-induced acute asthma."3.74[The regulatory effect of endogenous hydrogen sulfide on acute asthma]. ( Chen, YH; Geng, B; Lu, M; Tang, CS; Wu, R; Yao, WZ, 2007)
"The number of daily attendances for asthma attacks at the emergency room of Oulu University Central Hospital was recorded over one year together with daily meteorological readings (temperature, humidity, barometric pressure, rainfall), levels of air pollutants (nitrogen dioxide (NO2), sulphur dioxide (SO2), hydrogen sulphide (H2S), total suspended particles (TSP)), and pollen counts (birch, alder, pine, willow, total pollen)."3.68Association of severe asthma attacks with weather, pollen, and air pollutants. ( Huhti, E; Kinnula, VL; Rossi, OV; Tienari, J, 1993)
"Hydrogen sulfide (H2S)has emerged as pivotal signaling molecules since it is recognized as the third gasotransmitter together with nitric oxide and carbon monoxide."2.55[The Molecular Switches and Atomic Biological Mechanisms Underlying the Physiological and Pathophysio-logical Effects of Hydrogen Sulfide to Regulate Its "Receptors"]. ( Cai, WJ; Li, XH; Tao, BB; Wang, MJ; Xue, WL; Zhu, YC, 2017)
"Hydrogen sulfide (H2S) is a biologically active gas that is synthesized naturally by three enzymes, cystathionine γ-lyase (CSE), cystathionine β-synthetase (CBS) and 3-mercaptopyruvate sulfurtransferase (3-MST)."2.52H2S Synthesizing Enzymes: Biochemistry and Molecular Aspects. ( Huang, CW; Moore, PK, 2015)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.70)18.7374
1990's2 (7.41)18.2507
2000's4 (14.81)29.6817
2010's17 (62.96)24.3611
2020's3 (11.11)2.80

Authors

AuthorsStudies
Corvino, A1
Citi, V1
Fiorino, F1
Frecentese, F1
Magli, E1
Perissutti, E1
Santagada, V1
Calderone, V2
Martelli, A2
Gorica, E1
Brogi, S1
Colombo, FF1
Capello, CN1
Araujo Ferreira, HH1
Rimoli, MG1
Sodano, F1
Rolando, B1
Pavese, F1
Petti, A1
Muscará, MN2
Caliendo, G1
Severino, B1
Suzuki, Y2
Saito, J3
Munakata, M2
Shibata, Y1
Kroll, JL1
Werchan, CA1
Reeves, AG1
Bruemmer, KJ1
Lippert, AR1
Ritz, T1
Kikuchi, M1
Uematsu, M1
Fukuhara, A1
Sato, S1
Xue, WL1
Cai, WJ1
Tao, BB1
Wang, MJ1
Li, XH1
Zhu, YC1
Bates, MN2
Garrett, N2
Crane, J2
Balmes, JR2
Chung, KF2
Zhang, J1
Wang, X1
Chen, Y1
Yao, W1
Kaur, S1
Schwartz, AL1
Miller, TW1
Roberts, DD1
Huang, CW1
Moore, PK1
Roviezzo, F1
Bertolino, A1
Sorrentino, R1
Terlizzi, M1
Matteis, M1
Mattera, V1
Spaziano, G1
Pinto, A1
D'Agostino, B1
Cirino, G1
Campos, D1
Ravagnani, FG1
Gurgueira, SA1
Vercesi, AE1
Teixeira, SA1
Costa, SKP1
Ferreira, HHA1
Wang, P2
Wu, L1
Ju, Y1
Fu, M1
Shuang, T1
Qian, Z1
Wang, R2
Wu, R3
Yao, WZ3
Chen, YH3
Geng, B3
Tang, CS3
Qi, YF1
Wang, PP1
Li, SB1
Tong, XS1
Wang, XX1
Jin, XH1
Ye, H1
Zhang, G1
Wondimu, T1
Ross, B1
Carlsen, HK1
Zoëga, H1
Valdimarsdóttir, U1
Gíslason, T1
Hrafnkelsson, B1
Tian, M1
Wang, Y1
Lu, YQ1
Yan, M1
Jiang, YH1
Zhao, DY1
Zhang, Q1
Hui, C1
Macedo, P1
Gibeon, D1
Menzies-Gow, A1
Bhavsar, PK1
DREYFUS, S1
Campagna, D1
Kathman, SJ1
Pierson, R1
Inserra, SG1
Phifer, BL1
Middleton, DC1
Zarus, GM1
White, MC1
Lu, M1
Rossi, OV1
Kinnula, VL1
Tienari, J1
Huhti, E1
Jäppinen, P1
Vilkka, V1
Marttila, O1
Haahtela, T1

Reviews

4 reviews available for hydrogen sulfide and Asthma

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Hydrogen sulfide as a novel biomarker of asthma and chronic obstructive pulmonary disease.
    Allergology international : official journal of the Japanese Society of Allergology, 2021, Volume: 70, Issue:2

    Topics: Animals; Asthma; Biomarkers; Humans; Hydrogen Sulfide; Pulmonary Disease, Chronic Obstructive

2021
[The Molecular Switches and Atomic Biological Mechanisms Underlying the Physiological and Pathophysio-logical Effects of Hydrogen Sulfide to Regulate Its "Receptors"].
    Sheng li ke xue jin zhan [Progress in physiology], 2017, Volume: 48, Issue:1

    Topics: Asthma; Atherosclerosis; Carbon Monoxide; Cardiovascular System; Humans; Hydrogen Sulfide; Hypertens

2017
H2S Synthesizing Enzymes: Biochemistry and Molecular Aspects.
    Handbook of experimental pharmacology, 2015, Volume: 230

    Topics: Animals; Asthma; Atherosclerosis; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Diabetes M

2015

Trials

1 trial available for hydrogen sulfide and Asthma

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Other Studies

23 other studies available for hydrogen sulfide and Asthma

ArticleYear
H
    Journal of advanced research, 2022, Volume: 35

    Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Asthma; Disease Models, Animal; Humans;

2022
Sensitivity of salivary hydrogen sulfide to psychological stress and its association with exhaled nitric oxide and affect.
    Physiology & behavior, 2017, Oct-01, Volume: 179

    Topics: Adolescent; Adult; Affect; Asthma; Breath Tests; Educational Measurement; Exhalation; Female; Humans

2017
Sputum-to-serum hydrogen sulphide ratio as a novel biomarker of predicting future risks of asthma exacerbation.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2018, Volume: 48, Issue:9

    Topics: Adult; Aged; Asthma; Biomarkers; Cross-Sectional Studies; Cytokines; Disease Progression; Female; Hu

2018
Associations of ambient hydrogen sulfide exposure with self-reported asthma and asthma symptoms.
    Environmental research, 2013, Volume: 122

    Topics: Adolescent; Adult; Aged; Asthma; Cross-Sectional Studies; Female; Humans; Hydrogen Sulfide; Male; Mi

2013
Hydrogen sulfide as a potential biomarker of asthma.
    Expert review of respiratory medicine, 2014, Volume: 8, Issue:1

    Topics: Asthma; Biomarkers; Humans; Hydrogen Sulfide; Inflammation; Lung; Phenotype; Sputum

2014
Correlation between levels of exhaled hydrogen sulfide and airway inflammatory phenotype in patients with chronic persistent asthma.
    Respirology (Carlton, Vic.), 2014, Volume: 19, Issue:8

    Topics: Adult; Asthma; Biomarkers; Exhalation; Female; Forced Expiratory Volume; Humans; Hydrogen Sulfide; I

2014
CD47-dependent regulation of H₂S biosynthesis and signaling in T cells.
    Methods in enzymology, 2015, Volume: 555

    Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Asthma

2015
Investigation of hydrogen sulfide exposure and lung function, asthma and chronic obstructive pulmonary disease in a geothermal area of New Zealand.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Adolescent; Adult; Air Pollutants; Asthma; Bronchodilator Agents; Female; Humans; Hydrogen Sulfide;

2015
Hydrogen sulfide inhalation ameliorates allergen induced airway hypereactivity by modulating mast cell activation.
    Pharmacological research, 2015, Volume: 100

    Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Cell Transdifferentiation; Disease Models, An

2015
Increased glutathione levels contribute to the beneficial effects of hydrogen sulfide and inducible nitric oxide inhibition in allergic lung inflammation.
    International immunopharmacology, 2016, Volume: 39

    Topics: Aconitate Hydratase; Animals; Asthma; Cell Movement; Enzyme Inhibitors; Female; Glutathione; Hydroge

2016
Age-Dependent Allergic Asthma Development and Cystathionine Gamma-Lyase Deficiency.
    Antioxidants & redox signaling, 2017, Nov-01, Volume: 27, Issue:13

    Topics: Age Factors; Animals; Asthma; Cells, Cultured; Cystathionine gamma-Lyase; Cytokines; Disease Models,

2017
[Plasma level of endogenous hydrogen sulfide in patients with acute asthma].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2008, Oct-18, Volume: 40, Issue:5

    Topics: Acute Disease; Adult; Aged; Asthma; Biomarkers; Female; Humans; Hydrogen Sulfide; Male; Middle Aged;

2008
Endogenous hydrogen sulfide reduces airway inflammation and remodeling in a rat model of asthma.
    Cytokine, 2009, Volume: 45, Issue:2

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cystathionine gamma-Lyase; Disease Models, Animal; En

2009
[Regulative mechanism of budesonide on endogenous hydrogen sulfide, cystathionine-gamma-lyase and cystathionine-beta-synthase system in asthmatic rats].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2010, Volume: 12, Issue:8

    Topics: Animals; Asthma; Budesonide; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Hydrogen Sulfid

2010
Hydrogen sulfide and asthma.
    Experimental physiology, 2011, Volume: 96, Issue:9

    Topics: Airway Remodeling; Animals; Asthma; Biomarkers; Bronchoconstriction; Cystathionine beta-Synthase; Cy

2011
Hydrogen sulfide and particle matter levels associated with increased dispensing of anti-asthma drugs in Iceland's capital.
    Environmental research, 2012, Volume: 113

    Topics: Adult; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Anti-Asthmatic Agents; Asthma; Drug U

2012
Correlation between serum H2S and pulmonary function in children with bronchial asthma.
    Molecular medicine reports, 2012, Volume: 6, Issue:2

    Topics: Asthma; Blood Chemical Analysis; Case-Control Studies; Child; Female; Forced Expiratory Volume; Huma

2012
Sputum hydrogen sulfide as a novel biomarker of obstructive neutrophilic asthma.
    The Journal of allergy and clinical immunology, 2013, Volume: 131, Issue:1

    Topics: Adult; Asthma; Biomarkers; Female; Humans; Hydrogen Sulfide; Male; Middle Aged; Sputum; Young Adult

2013
[The spasmolytic effect of pyribenzamine-ritalin as an admixture to inhalation of hydrogen sulfide-containing mineral springs].
    Praxis, 1962, Feb-22, Volume: 51

    Topics: Asthma; Humans; Hydrogen Sulfide; Methylphenidate; Mineral Waters; Minerals; Parasympatholytics; Res

1962
Ambient hydrogen sulfide, total reduced sulfur, and hospital visits for respiratory diseases in northeast Nebraska, 1998-2000.
    Journal of exposure analysis and environmental epidemiology, 2004, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Air Pollutants; Asthma; Child; Digestive System Diseases; Emergency Service, Hosp

2004
[The regulatory effect of endogenous hydrogen sulfide on acute asthma].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2007, Volume: 30, Issue:7

    Topics: Animals; Asthma; Cystathionine gamma-Lyase; Disease Models, Animal; Hydrogen Sulfide; Lung; Male; Ov

2007
Association of severe asthma attacks with weather, pollen, and air pollutants.
    Thorax, 1993, Volume: 48, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Air Pollutants; Asthma; Cold Temperature; Female; Humans

1993
Exposure to hydrogen sulphide and respiratory function.
    British journal of industrial medicine, 1990, Volume: 47, Issue:12

    Topics: Adult; Asthma; Bronchial Provocation Tests; Cohort Studies; Forced Expiratory Volume; Humans; Hydrog

1990