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hydrogen sulfide and Angiogenesis, Pathologic

hydrogen sulfide has been researched along with Angiogenesis, Pathologic in 25 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Research Excerpts

ExcerptRelevanceReference
"To address the hypothesis that hydrogen sulfide (H(2)S) is a functionally significant stimulator in the development of glioblastoma (GBM) and explore the mechanism of stimulation."7.78[Hydrogen sulfide stimulates the development of rat glioblastoma]. ( Li, ZY; Liu, SC; Xu, PJ; Yang, Z; Zhang, T, 2012)
"Hydrogen sulfide (H2S) is an endogenous gaseous signaling molecule with significant pathophysiological importance, but its role in retinal neovascular diseases is unknown."5.43Hydrogen Sulfide Contributes to Retinal Neovascularization in Ischemia-Induced Retinopathy. ( Coletta, C; Gersztenkorn, D; Ha, Y; Liu, H; Motamedi, M; Szabo, C; Tie, H; Zhang, W; Zhou, J; Zhu, S, 2016)
"Hydrogen sulfide (H2 S) is a potent vasodilator and regulates cardiovascular homeostasis."5.40Hydrogen sulfide treatment induces angiogenesis after cerebral ischemia. ( Choi, IY; Jang, H; Kim, YJ; Lee, SH; Oh, MY; Ryu, WS; Yang, HS; Yoon, BW, 2014)
"To address the hypothesis that hydrogen sulfide (H(2)S) is a functionally significant stimulator in the development of glioblastoma (GBM) and explore the mechanism of stimulation."3.78[Hydrogen sulfide stimulates the development of rat glioblastoma]. ( Li, ZY; Liu, SC; Xu, PJ; Yang, Z; Zhang, T, 2012)
"In addition to promoting cancer cell death, H2S donors were also found to inhibit cancer angiogenesis and metastasis."2.52Role of H2S Donors in Cancer Biology. ( Deng, LW; Lee, ZW, 2015)
" In patients with diabetes, a lower bioavailability of the different gasotransmitters is observed when compared with healthy individuals."1.43Gasotransmitters in Vascular Complications of Diabetes. ( Greffrath, W; Hammes, HP; Hillebrands, JL; van den Born, JC; van Goor, H, 2016)
"Hydrogen sulfide (H2S) is an endogenous gaseous signaling molecule with significant pathophysiological importance, but its role in retinal neovascular diseases is unknown."1.43Hydrogen Sulfide Contributes to Retinal Neovascularization in Ischemia-Induced Retinopathy. ( Coletta, C; Gersztenkorn, D; Ha, Y; Liu, H; Motamedi, M; Szabo, C; Tie, H; Zhang, W; Zhou, J; Zhu, S, 2016)
"PLC/PRF/5 hepatoma cells were pretreated with 500 µmol/l NaHS (a donor of H2S) for 24 h."1.42Exogenous hydrogen sulfide exerts proliferation/anti-apoptosis/angiogenesis/migration effects via amplifying the activation of NF-κB pathway in PLC/PRF/5 hepatoma cells. ( Chen, J; Feng, J; Hu, F; Pan, W; Wu, H; Zhang, Y; Zhen, Y, 2015)
"Hydrogen sulfide (H2S) is an endogenously-produced gasotransmitter that accumulates under hypoxia and has been shown to be pro-angiogenic and cytoprotective in cancer."1.42Inhibition of endogenous hydrogen sulfide production in clear-cell renal cell carcinoma cell lines and xenografts restricts their growth, survival and angiogenic potential. ( Chambers, AF; Hammers, MD; Leong, HS; Lobb, I; Mazzola, CR; Pardhan, S; Pluth, MD; Postenka, CO; Power, NE; Sener, A; Sonke, E; Verrydt, M; Willie, CJ, 2015)
"Hydrogen sulfide (H2 S) is a potent vasodilator and regulates cardiovascular homeostasis."1.40Hydrogen sulfide treatment induces angiogenesis after cerebral ischemia. ( Choi, IY; Jang, H; Kim, YJ; Lee, SH; Oh, MY; Ryu, WS; Yang, HS; Yoon, BW, 2014)
"Analysis of human colon cancer biopsies and patient-matched normal margin mucosa revealed the selective up-regulation of the H2S-producing enzyme cystathionine-β-synthase (CBS) in colon cancer, resulting in an increased rate of H2S production."1.39Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer. ( Chao, C; Coletta, C; Hellmich, MR; Módis, K; Papapetropoulos, A; Szabo, C; Szczesny, B, 2013)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (4.00)29.6817
2010's18 (72.00)24.3611
2020's6 (24.00)2.80

Authors

AuthorsStudies
Mendiola, PJ1
Naik, JS1
Gonzalez Bosc, LV1
Gardiner, AS1
Birg, A1
Kanagy, NL2
Xue, W1
Zhang, Q1
Chen, Y2
Zhu, Y3
Ascenção, K1
Lheimeur, B1
Szabo, C5
Wang, M1
Yan, J1
Cao, X1
Hua, P1
Li, Z1
Wang, D1
Yang, H1
Zhang, Y2
Hu, R1
Hu, D1
Wang, Q1
Liu, Y2
Liu, M1
Meng, Z1
Zhou, W1
Song, W1
Li, M1
Deng, Y1
Pan, L2
Fu, H1
Han, X1
Li, Y1
Shi, H1
Wang, T1
Rajendran, S1
Shen, X1
Glawe, J1
Kolluru, GK1
Kevil, CG2
Altaany, Z1
Yang, G1
Wang, R1
Coletta, C2
Chao, C1
Módis, K1
Szczesny, B1
Papapetropoulos, A2
Hellmich, MR2
Kan, J1
Guo, W1
Huang, C1
Bao, G1
Zhu, YZ1
Jang, H1
Oh, MY1
Kim, YJ1
Choi, IY1
Yang, HS1
Ryu, WS1
Lee, SH1
Yoon, BW1
Zhen, Y2
Pan, W1
Hu, F1
Wu, H1
Feng, J2
Chen, J2
Sonke, E1
Verrydt, M1
Postenka, CO1
Pardhan, S1
Willie, CJ1
Mazzola, CR1
Hammers, MD1
Pluth, MD1
Lobb, I1
Power, NE1
Chambers, AF1
Leong, HS1
Sener, A1
Lee, ZW1
Deng, LW1
Yuan, S1
van den Born, JC1
Hammes, HP1
Greffrath, W1
van Goor, H1
Hillebrands, JL1
Lei, Y1
Zhang, W2
Sun, X1
Lin, X1
Luo, H1
Chen, Z1
Su, C1
Zeng, B1
Gersztenkorn, D1
Zhu, S1
Ha, Y1
Liu, H1
Tie, H1
Zhou, J1
Motamedi, M1
Taylor, CE1
Miller, TW1
Isenberg, JS1
Roberts, DD1
Wang, MJ1
Cai, WJ1
Li, N1
Ding, YJ1
Zhu, YC1
Liu, X1
Zhuo, Y1
Gong, Q1
Rose, P1
Li, ZY1
Liu, SC1
Xu, PJ1
Yang, Z1
Zhang, T1

Reviews

6 reviews available for hydrogen sulfide and Angiogenesis, Pathologic

ArticleYear
Therapeutic potential of endogenous hydrogen sulfide inhibition in breast cancer (Review).
    Oncology reports, 2021, Volume: 45, Issue:5

    Topics: Animals; Apoptosis; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cystathi

2021
Nitric Oxide and Hydrogen Sulfide Regulation of Ischemic Vascular Growth and Remodeling.
    Comprehensive Physiology, 2019, 06-12, Volume: 9, Issue:3

    Topics: Cardiovascular Diseases; Humans; Hydrogen Sulfide; Intercellular Signaling Peptides and Proteins; Is

2019
Role of H2S Donors in Cancer Biology.
    Handbook of experimental pharmacology, 2015, Volume: 230

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Humans; Hydrogen Sulfide; Neoplas

2015
Nitric Oxide and Hydrogen Sulfide Regulation of Ischemic Vascular Remodeling.
    Microcirculation (New York, N.Y. : 1994), 2016, Volume: 23, Issue:2

    Topics: Animals; Humans; Hydrogen Sulfide; Ischemia; Neovascularization, Pathologic; Nitric Oxide; Vascular

2016
Vascular biology of hydrogen sulfide.
    American journal of physiology. Cell physiology, 2017, May-01, Volume: 312, Issue:5

    Topics: Animals; Arteries; Atherosclerosis; Humans; Hydrogen Sulfide; Models, Cardiovascular; Neovasculariza

2017
Molecular regulation of tumor angiogenesis and perfusion via redox signaling.
    Chemical reviews, 2009, Volume: 109, Issue:7

    Topics: Angiogenesis Inhibitors; Angiogenic Proteins; Animals; Carbon Monoxide; Humans; Hydrogen Peroxide; H

2009

Other Studies

19 other studies available for hydrogen sulfide and Angiogenesis, Pathologic

ArticleYear
Hydrogen Sulfide Actions in the Vasculature.
    Comprehensive Physiology, 2021, 09-23, Volume: 11, Issue:4

    Topics: Humans; Hydrogen Sulfide; Inflammation; Neovascularization, Pathologic; Oxidation-Reduction; Signal

2021
Hydrogen Sulfide Improves Angiogenesis by Regulating the Transcription of pri-miR-126 in Diabetic Endothelial Cells.
    Cells, 2022, 08-25, Volume: 11, Issue:17

    Topics: Angiogenesis Inducing Agents; Animals; Diabetes Mellitus, Experimental; Glucose; Human Umbilical Vei

2022
Regulation of CyR61 expression and release by 3-mercaptopyruvate sulfurtransferase in colon cancer cells.
    Redox biology, 2022, Volume: 56

    Topics: Aminooxyacetic Acid; Antineoplastic Agents; Colonic Neoplasms; Cystathionine; Cystathionine beta-Syn

2022
Hydrogen sulfide modulates epithelial-mesenchymal transition and angiogenesis in non-small cell lung cancer via HIF-1α activation.
    Biochemical pharmacology, 2020, Volume: 172

    Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Movement; Cel

2020
Inhibition of cystathionine β-synthase promotes apoptosis and reduces cell proliferation in chronic myeloid leukemia.
    Signal transduction and targeted therapy, 2021, 02-08, Volume: 6, Issue:1

    Topics: Animals; Apoptosis; Bone Marrow Cells; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Child;

2021
Crosstalk between hydrogen sulfide and nitric oxide in endothelial cells.
    Journal of cellular and molecular medicine, 2013, Volume: 17, Issue:7

    Topics: Cell Proliferation; Chromones; Collagen; Cystathionine gamma-Lyase; Drug Combinations; Endothelial C

2013
Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Jul-23, Volume: 110, Issue:30

    Topics: Animals; Cell Proliferation; Colonic Neoplasms; Cystathionine beta-Synthase; Energy Metabolism; Fema

2013
Endogenously produced hydrogen sulfide supports tumor cell growth and proliferation.
    Cell cycle (Georgetown, Tex.), 2013, Sep-15, Volume: 12, Issue:18

    Topics: Animals; Cell Proliferation; Colonic Neoplasms; Cystathionine beta-Synthase; Energy Metabolism; Fema

2013
S-propargyl-cysteine, a novel water-soluble modulator of endogenous hydrogen sulfide, promotes angiogenesis through activation of signal transducer and activator of transcription 3.
    Antioxidants & redox signaling, 2014, May-20, Volume: 20, Issue:15

    Topics: Active Transport, Cell Nucleus; Angiogenesis Inducing Agents; Animals; Cell Adhesion; Cell Movement;

2014
Hydrogen sulfide treatment induces angiogenesis after cerebral ischemia.
    Journal of neuroscience research, 2014, Volume: 92, Issue:11

    Topics: Analysis of Variance; Angiogenesis Inhibitors; Animals; Brain Infarction; Brain Ischemia; Cells, Cul

2014
Exogenous hydrogen sulfide exerts proliferation/anti-apoptosis/angiogenesis/migration effects via amplifying the activation of NF-κB pathway in PLC/PRF/5 hepatoma cells.
    International journal of oncology, 2015, Volume: 46, Issue:5

    Topics: Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proli

2015
Inhibition of endogenous hydrogen sulfide production in clear-cell renal cell carcinoma cell lines and xenografts restricts their growth, survival and angiogenic potential.
    Nitric oxide : biology and chemistry, 2015, Sep-15, Volume: 49

    Topics: Animals; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chick Embryo; H

2015
Gasotransmitters in Vascular Complications of Diabetes.
    Diabetes, 2016, Volume: 65, Issue:2

    Topics: Biological Availability; Carbon Monoxide; Diabetes Mellitus; Diabetic Angiopathies; Gasotransmitters

2016
Exogenous hydrogen sulfide exerts proliferation, anti-apoptosis, angiopoiesis and migration effects via activating HSP90 pathway in EC109 cells.
    Oncology reports, 2016, Volume: 35, Issue:6

    Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Proliferatio

2016
Hydrogen Sulfide Contributes to Retinal Neovascularization in Ischemia-Induced Retinopathy.
    Investigative ophthalmology & visual science, 2016, 06-01, Volume: 57, Issue:7

    Topics: Animals; Blotting, Western; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Disease Models,

2016
A novel treatment for "morning sickness": Nausea of pregnancy could be induced by excess sulfite which molybdenum can help alleviate.
    Medical hypotheses, 2016, Volume: 95

    Topics: Catalysis; Female; Humans; Hydrogen Sulfide; Models, Theoretical; Molybdenum; Morning Sickness; Naus

2016
The hydrogen sulfide donor NaHS promotes angiogenesis in a rat model of hind limb ischemia.
    Antioxidants & redox signaling, 2010, May-01, Volume: 12, Issue:9

    Topics: Animals; Cell Communication; Endothelial Cells; Extremities; Hemodynamics; Hydrogen Sulfide; Ischemi

2010
Hypoxia-inducible factor-1α is involved in the pro-angiogenic effect of hydrogen sulfide under hypoxic stress.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:9

    Topics: Animals; Cell Hypoxia; Cell Proliferation; Cell Survival; Cells, Cultured; Cerebrovascular Circulati

2010
[Hydrogen sulfide stimulates the development of rat glioblastoma].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2012, Volume: 34, Issue:4

    Topics: Animals; Antigens, CD34; Brain; Brain Neoplasms; Glioblastoma; Hydrogen Sulfide; Hypoxia-Inducible F

2012