hydrogen sulfide has been researched along with Alloxan Diabetes in 69 studies
Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rats with type 2 diabetes were exposed to GYY4137, a slow release donor of hydrogen sulfide with or without administration of the Sirtuin3 short hairpin ribonucleic acid plasmid, and then subjected to a surgical model of ischemia-reperfusion injury of the lung (n = 8)." | 7.91 | Hydrogen sulfide attenuates lung ischemia-reperfusion injury through SIRT3-dependent regulation of mitochondrial function in type 2 diabetic rats. ( Cui, X; Ding, W; Jiang, T; Liu, T; Liu, Y; Lv, X; Meng, Q; Yue, Z, 2019) |
| "The aim of the present study was to determine the role of hydrogen sulfide (H2S) in improving myocardial fibrosis and its effects on oxidative stress, endoplasmic reticulum (ER) stress and cell apoptosis in diabetic rats, by regulating the Janus kinase̸signal transducer and activator of transcription (JAK̸STAT) signaling pathway." | 7.88 | Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway. ( Chu, C; Jiang, Z; Li, Y; Li, Z; Liang, B; Liu, M; Yang, J, 2018) |
| "The present study aimed to explore the effect of hydrogen sulfide (H2S) on renal tissue fibrosis and its mechanism in diabetic rats." | 7.85 | Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats. ( Chu, C; Li, F; Li, L; Li, Y; Li, Z; Liang, B; Liu, M; Xiao, T; Yang, J; Zeng, O, 2017) |
| "To explore the eff ect of hydrogen sulfide (H2S) on protein kinase C α (PKCα) and heat shock protein 70 (HSP70) expression and myocardial fibrosis in diabetic rats." | 7.81 | [Effect of hydrogen sulfide on myocardial fibrosis and expression of PKCα and HSP70 in diabetic rats]. ( Li, F; Luo, J; Wu, Z; Xiao, T; Yang, J; Zhang, J, 2015) |
| "To explore the effects of hydrogen sulfide (H(2)S) on myocardial fibrosis and expressions of MAPK1/3 and MMP-8 in diabetic rats." | 7.81 | [Effects of hydrogen sulfide on myocardial fibrosis and MAPK1/3 and MMP-8 expression in diabetic rats]. ( Li, F; Luo, J; Wu, ZX; Xiao, T; Yang, J; Zeng, O; Zhang, JJ, 2015) |
| "In order to explore the effects of hydrogen sulfide (H2S) on myocardial fibrosis in diabetic rats and its underlying mechanisms, intraperitoneal injections of streptozotocin were used to establish the diabetes models and sodium hydrosulfide (NaHS) was used as an exogenous donor of H2S." | 7.81 | Effects of hydrogen sulfide on myocardial fibrosis in diabetic rats: Changes in matrix metalloproteinases parameters. ( Li, F; Luo, J; Wu, Z; Xiao, T; Yang, J; Zeng, O, 2015) |
| " The aim of present study was to investigate the therapeutic effect of hydrogen sulfide on streptozotocin (STZ)-induced diabetic retinopathy in rats." | 7.79 | Treatment with hydrogen sulfide alleviates streptozotocin-induced diabetic retinopathy in rats. ( Guan, J; Sheng, Y; Si, YF; Wang, J; Zhao, J; Zhou, L, 2013) |
| "Hydrogen sulfide (H2S) has drawn considerable attention in recent years for its potential as a cardiovascular protector." | 5.56 | Exogenous hydrogen sulfide reduces atrial remodeling and atrial fibrillation induced by diabetes mellitus via activation of the PI3K/Akt/eNOS pathway. ( Ling, X; Sun, J; Wang, P; Xi, W; Xiao, J; Xue, X; Yang, Q, 2020) |
| "Myocardial fibrosis is the predominant pathological characteristic of diabetic myocardial damage." | 5.43 | Effects of hydrogen sulfide on myocardial fibrosis and PI3K/AKT1-regulated autophagy in diabetic rats. ( Li, F; Luo, J; Wu, Z; Xiao, T; Yang, J; Zeng, O, 2016) |
| "Hydrogen sulfide (H2S) is an endogenous gasotransmitter." | 5.43 | Decreased Endogenous Hydrogen Sulfide Generation in Penile Tissues of Diabetic Rats with Erectile Dysfunction. ( Liu, JH; Wang, SG; Wang, T; Yang, J; Ye, ZQ; Yin, CP; Zhang, Y, 2016) |
| "Hydrogen sulfide (H2S) is a gasotransmitter endogenously generated from the metabolism of L-cysteine by action of two main enzymes called cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE)." | 5.39 | Role of hydrogen sulfide in the pain processing of non-diabetic and diabetic rats. ( Araiza-Saldaña, CI; Barragán-Iglesias, P; Flores-Murrieta, FJ; Godínez-Chaparro, B; Navarrete, A; Roa-Coria, JE; Rocha-González, HI; Torres-López, JE; Velasco-Xolalpa, ME, 2013) |
| "Rats with type 2 diabetes were exposed to GYY4137, a slow release donor of hydrogen sulfide with or without administration of the Sirtuin3 short hairpin ribonucleic acid plasmid, and then subjected to a surgical model of ischemia-reperfusion injury of the lung (n = 8)." | 3.91 | Hydrogen sulfide attenuates lung ischemia-reperfusion injury through SIRT3-dependent regulation of mitochondrial function in type 2 diabetic rats. ( Cui, X; Ding, W; Jiang, T; Liu, T; Liu, Y; Lv, X; Meng, Q; Yue, Z, 2019) |
| "OBJECTIVETo investigate the roles and underlying mechanism of exogenous H2S (hydrogen sulfide) in attenuating the myocardial fibrosis in diabetic rats." | 3.91 | H2S attenuates the myocardial fibrosis in diabetic rats through modulating PKC-ERK1/2MAPK signaling pathway. ( Chu, C; Liu, M; Liu, S; Long, J; Tan, W; Tang, F; Xiao, T; Yang, J, 2019) |
| "The aim of the present study was to determine the role of hydrogen sulfide (H2S) in improving myocardial fibrosis and its effects on oxidative stress, endoplasmic reticulum (ER) stress and cell apoptosis in diabetic rats, by regulating the Janus kinase̸signal transducer and activator of transcription (JAK̸STAT) signaling pathway." | 3.88 | Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway. ( Chu, C; Jiang, Z; Li, Y; Li, Z; Liang, B; Liu, M; Yang, J, 2018) |
| "The present study aimed to explore the effect of hydrogen sulfide (H2S) on renal tissue fibrosis and its mechanism in diabetic rats." | 3.85 | Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats. ( Chu, C; Li, F; Li, L; Li, Y; Li, Z; Liang, B; Liu, M; Xiao, T; Yang, J; Zeng, O, 2017) |
| "To explore the eff ect of hydrogen sulfide (H2S) on protein kinase C α (PKCα) and heat shock protein 70 (HSP70) expression and myocardial fibrosis in diabetic rats." | 3.81 | [Effect of hydrogen sulfide on myocardial fibrosis and expression of PKCα and HSP70 in diabetic rats]. ( Li, F; Luo, J; Wu, Z; Xiao, T; Yang, J; Zhang, J, 2015) |
| "To explore the effects of hydrogen sulfide (H(2)S) on myocardial fibrosis and expressions of MAPK1/3 and MMP-8 in diabetic rats." | 3.81 | [Effects of hydrogen sulfide on myocardial fibrosis and MAPK1/3 and MMP-8 expression in diabetic rats]. ( Li, F; Luo, J; Wu, ZX; Xiao, T; Yang, J; Zeng, O; Zhang, JJ, 2015) |
| "In order to explore the effects of hydrogen sulfide (H2S) on myocardial fibrosis in diabetic rats and its underlying mechanisms, intraperitoneal injections of streptozotocin were used to establish the diabetes models and sodium hydrosulfide (NaHS) was used as an exogenous donor of H2S." | 3.81 | Effects of hydrogen sulfide on myocardial fibrosis in diabetic rats: Changes in matrix metalloproteinases parameters. ( Li, F; Luo, J; Wu, Z; Xiao, T; Yang, J; Zeng, O, 2015) |
| "To investigate the impact of hyperglycemia on the hydrogen sulfide (H2S) signaling pathway in rat penile tissue and its relationship with erectile function." | 3.80 | [Expressions of CSE and CBS in the penile corpus cavernosum of hyperglycemia rats and their implications]. ( Huang, YM; Jiang, R; Xia, JY, 2014) |
| "Accumulating evidence has demonstrated that hydrogen sulfide (H2S) plays critical roles in the pathogenesis of chronic kidney diseases." | 3.80 | Hydrogen sulfide alleviates diabetic nephropathy in a streptozotocin-induced diabetic rat model. ( Chen, J; Feng, Y; Zhan, Z; Zhou, X, 2014) |
| " The aim of present study was to investigate the therapeutic effect of hydrogen sulfide on streptozotocin (STZ)-induced diabetic retinopathy in rats." | 3.79 | Treatment with hydrogen sulfide alleviates streptozotocin-induced diabetic retinopathy in rats. ( Guan, J; Sheng, Y; Si, YF; Wang, J; Zhao, J; Zhou, L, 2013) |
| "Hydrogen sulfide (H2S) has drawn considerable attention in recent years for its potential as a cardiovascular protector." | 1.56 | Exogenous hydrogen sulfide reduces atrial remodeling and atrial fibrillation induced by diabetes mellitus via activation of the PI3K/Akt/eNOS pathway. ( Ling, X; Sun, J; Wang, P; Xi, W; Xiao, J; Xue, X; Yang, Q, 2020) |
| " Chronic administration of NaSH in particular at high doses impaired carbohydrate metabolism in type 2 diabetic rats." | 1.51 | Effects of Hydrogen Sulfide on Carbohydrate Metabolism in Obese Type 2 Diabetic Rats. ( Ghasemi, A; Gheibi, S; Jeddi, S; Kashfi, K, 2019) |
| "Hydrogen sulfide (H2S) has antifibrotic activity in the kidneys, heart, lungs, and other organs." | 1.51 | Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway. ( Chen, Y; Jia, Q; Ma, SF; Mehmood, S; Wang, Y; Yang, R, 2019) |
| "Myocardial fibrosis is the predominant pathological characteristic of diabetic myocardial damage." | 1.43 | Effects of hydrogen sulfide on myocardial fibrosis and PI3K/AKT1-regulated autophagy in diabetic rats. ( Li, F; Luo, J; Wu, Z; Xiao, T; Yang, J; Zeng, O, 2016) |
| "Hydrogen sulfide (H2S) is an endogenous gasotransmitter." | 1.43 | Decreased Endogenous Hydrogen Sulfide Generation in Penile Tissues of Diabetic Rats with Erectile Dysfunction. ( Liu, JH; Wang, SG; Wang, T; Yang, J; Ye, ZQ; Yin, CP; Zhang, Y, 2016) |
| "001), reduced NO bioavailability and H2S production (P<0." | 1.42 | Ginkgolide B increases hydrogen sulfide and protects against endothelial dysfunction in diabetic rats. ( Chen, QY; Li, W; Lu, XH; Wang, GG; Zhao, X, 2015) |
| "In vivo, NaHS treatment inhibited hyperglycemia-induced expression of type I and III collagen, MMP-2 and MMP-9 in diabetic hearts." | 1.42 | Exogenous Hydrogen Sulfide Attenuates Cardiac Fibrosis Through Reactive Oxygen Species Signal Pathways in Experimental Diabetes Mellitus Models. ( Dong, S; Li, T; Lu, F; Wang, L; Wu, J; Xu, C; Yang, F; Yu, X; Zhang, W; Zhao, Y; Zheng, D; Zhong, X, 2015) |
| "Sodium bisulfide treatment raised the activity of superoxide dismutase (SOD) and heme oxygenase-1 (HO-1) protein expression, and decreased tumor necrosis factor α (TNF-α) protein expression in diabetic rats." | 1.42 | Hydrogen sulfide accelerates wound healing in diabetic rats. ( Chen, Q; Jiang, Y; Li, W; Lu, X; Wang, G; Zhao, X, 2015) |
| "Hydrogen sulfide (H2S) is a gasotransmitter endogenously generated from the metabolism of L-cysteine by action of two main enzymes called cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE)." | 1.39 | Role of hydrogen sulfide in the pain processing of non-diabetic and diabetic rats. ( Araiza-Saldaña, CI; Barragán-Iglesias, P; Flores-Murrieta, FJ; Godínez-Chaparro, B; Navarrete, A; Roa-Coria, JE; Rocha-González, HI; Torres-López, JE; Velasco-Xolalpa, ME, 2013) |
| "Hydrogen sulfide (H(2)S) displays anti-inflammatory and cytoprotective activities to attenuate myocardial ischemia-reperfusion (MIR)-induced injury, but its role in MIR in diabetics is not known." | 1.37 | The protective role of hydrogen sulfide in myocardial ischemia-reperfusion-induced injury in diabetic rats. ( Gao, Y; Kang, K; Li, W; Sun, L; Sun, X; Yao, X; Zhang, Y, 2011) |
| "Hydrogen sulfide (H₂S) is an endogenous gas which has potent relaxant effect in vascular and nonvascular smooth muscles." | 1.37 | The vasorelaxant effect of hydrogen sulfide is enhanced in streptozotocin-induced diabetic rats. ( Abacıoğlu, N; Akpulat, U; Bozkurt, TE; Denizalti, M; Sahin-Erdemli, I, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (2.90) | 29.6817 |
| 2010's | 53 (76.81) | 24.3611 |
| 2020's | 14 (20.29) | 2.80 |
| Authors | Studies |
|---|---|
| Dugbartey, GJ | 1 |
| Wonje, QL | 1 |
| Alornyo, KK | 1 |
| Adams, I | 1 |
| Diaba, DE | 1 |
| Xue, W | 1 |
| Zhang, Q | 2 |
| Chen, Y | 4 |
| Zhu, Y | 3 |
| Gheibi, S | 3 |
| Jeddi, S | 3 |
| Carlström, M | 2 |
| Kashfi, K | 3 |
| Ghasemi, A | 3 |
| Liu, HY | 1 |
| Wei, HJ | 2 |
| Wu, L | 4 |
| Liu, SM | 1 |
| Tang, YY | 1 |
| Zou, W | 2 |
| Wang, CY | 1 |
| Zhang, P | 3 |
| Tang, XQ | 2 |
| Elbassuoni, EA | 1 |
| Аziz, NM | 1 |
| Habeeb, WN | 1 |
| Jia, Q | 11 |
| Mehmood, S | 3 |
| Liu, X | 6 |
| Ma, S | 6 |
| Yang, R | 11 |
| Li, Y | 3 |
| Xue, X | 1 |
| Ling, X | 1 |
| Xi, W | 1 |
| Wang, P | 1 |
| Sun, J | 1 |
| Yang, Q | 1 |
| Xiao, J | 1 |
| Dorofeyeva, NA | 1 |
| Korkach, IP | 1 |
| Kutsyk, OE | 1 |
| Sagach, VF | 1 |
| Xi, YX | 1 |
| Wen, X | 1 |
| Jiao, LJ | 1 |
| Wei, YX | 1 |
| Chang, GQ | 1 |
| Wu, R | 1 |
| Sun, FQ | 1 |
| Hao, JH | 1 |
| Li, HZ | 1 |
| Zhang, J | 2 |
| Cai, X | 1 |
| Li, X | 2 |
| Li, S | 3 |
| Ma, J | 1 |
| Zhu, W | 1 |
| Wei, M | 1 |
| Tu, W | 1 |
| Shen, Y | 2 |
| Liu, J | 4 |
| Lai, X | 1 |
| Yu, P | 1 |
| Mohammad, G | 1 |
| Radhakrishnan, R | 1 |
| Kowluru, RA | 1 |
| Wang, L | 5 |
| Tang, Y | 1 |
| He, H | 1 |
| Wei, W | 1 |
| Yu, Y | 1 |
| Xiao, L | 1 |
| Ren, Z | 1 |
| Zhu, G | 1 |
| Wang, W | 2 |
| Jia, Y | 1 |
| Peng, A | 1 |
| Wang, X | 2 |
| Chen, GP | 1 |
| Zhang, XQ | 1 |
| Wu, T | 1 |
| Han, J | 1 |
| Ye, D | 1 |
| Zhong, D | 1 |
| Ma, P | 1 |
| Li, G | 1 |
| Hua, W | 1 |
| Sun, Y | 1 |
| Liu, N | 1 |
| Zhang, L | 2 |
| Zhang, W | 6 |
| Cui, S | 1 |
| Wang, Y | 6 |
| Gao, Q | 6 |
| Wang, J | 2 |
| Han, Y | 1 |
| Meng, G | 1 |
| Xiao, Y | 1 |
| Xie, L | 1 |
| Sha, J | 1 |
| Chen, Q | 2 |
| Moore, PK | 2 |
| Wang, R | 6 |
| Xiang, W | 1 |
| Ji, Y | 1 |
| Li, L | 1 |
| Xiao, T | 6 |
| Li, F | 5 |
| Zeng, O | 4 |
| Liu, M | 3 |
| Liang, B | 2 |
| Li, Z | 2 |
| Chu, C | 3 |
| Yang, J | 8 |
| Liu, XF | 4 |
| Wang, YY | 1 |
| Ma, SF | 5 |
| Jiang, Z | 2 |
| Li, ZH | 1 |
| Roa-Coria, JE | 2 |
| Pineda-Farias, JB | 1 |
| Barragán-Iglesias, P | 2 |
| Quiñonez-Bastidas, GN | 1 |
| Zúñiga-Romero, Á | 1 |
| Huerta-Cruz, JC | 1 |
| Reyes-García, JG | 1 |
| Flores-Murrieta, FJ | 2 |
| Granados-Soto, V | 1 |
| Rocha-González, HI | 2 |
| Ansari, M | 1 |
| Kurian, GA | 1 |
| Jiang, T | 1 |
| Liu, Y | 1 |
| Meng, Q | 1 |
| Lv, X | 1 |
| Yue, Z | 1 |
| Ding, W | 1 |
| Liu, T | 1 |
| Cui, X | 1 |
| Centeno, JM | 1 |
| López-Morales, MA | 1 |
| Aliena-Valero, A | 1 |
| Jover-Mengual, T | 1 |
| Burguete, MC | 1 |
| Castelló-Ruiz, M | 1 |
| Miranda, FJ | 1 |
| Wang, QY | 1 |
| Long, J | 1 |
| Liu, S | 1 |
| Tang, F | 1 |
| Tan, W | 1 |
| Luhinich, N | 1 |
| Gerush, I | 1 |
| Si, YF | 1 |
| Guan, J | 1 |
| Zhou, L | 3 |
| Sheng, Y | 1 |
| Zhao, J | 2 |
| Velasco-Xolalpa, ME | 1 |
| Godínez-Chaparro, B | 1 |
| Torres-López, JE | 1 |
| Araiza-Saldaña, CI | 1 |
| Navarrete, A | 1 |
| Xue, H | 2 |
| Yuan, P | 2 |
| Ni, J | 2 |
| Li, C | 2 |
| Shao, D | 1 |
| Wang, Z | 2 |
| Huang, Y | 2 |
| Yu, C | 2 |
| Lu, L | 2 |
| Talaei, F | 1 |
| Van Praag, VM | 1 |
| Shishavan, MH | 1 |
| Landheer, SW | 1 |
| Buikema, H | 1 |
| Henning, RH | 1 |
| Huang, YM | 1 |
| Xia, JY | 1 |
| Jiang, R | 1 |
| Zhou, X | 1 |
| Feng, Y | 1 |
| Zhan, Z | 1 |
| Chen, J | 1 |
| Safar, MM | 1 |
| Abdelsalam, RM | 1 |
| Luo, J | 4 |
| Wu, Z | 3 |
| Wang, GG | 1 |
| Chen, QY | 1 |
| Li, W | 3 |
| Lu, XH | 1 |
| Zhao, X | 2 |
| Zhong, X | 4 |
| Wu, J | 4 |
| Sun, A | 2 |
| Yang, F | 3 |
| Zheng, D | 2 |
| Li, T | 3 |
| Dong, S | 4 |
| Zhao, Y | 4 |
| Yang, G | 3 |
| Xu, C | 4 |
| Sun, D | 1 |
| Lu, F | 4 |
| Wu, ZX | 1 |
| Zhang, JJ | 1 |
| Tang, ZJ | 1 |
| Yuan, J | 1 |
| Tian, Y | 1 |
| Xiao, ZF | 1 |
| Li, MH | 1 |
| Yang, H | 1 |
| Mao, Y | 1 |
| Tan, B | 2 |
| Luo, S | 2 |
| Jin, S | 1 |
| Pu, SX | 1 |
| Hou, CL | 1 |
| Ma, FF | 1 |
| Li, N | 1 |
| Li, XH | 2 |
| Tao, BB | 1 |
| Wang, MJ | 1 |
| Zhu, YC | 2 |
| Yu, X | 2 |
| Wang, G | 1 |
| Jiang, Y | 1 |
| Lu, X | 1 |
| Guo, X | 1 |
| Guan, S | 1 |
| Zhang, Y | 2 |
| Wang, T | 1 |
| Wang, SG | 1 |
| Liu, JH | 1 |
| Yin, CP | 1 |
| Ye, ZQ | 1 |
| Cheng, YS | 1 |
| Dai, DZ | 1 |
| Dai, Y | 1 |
| Zhu, DD | 1 |
| Liu, BC | 1 |
| Qian, X | 1 |
| Ma, F | 1 |
| Ge, R | 1 |
| El-Sayed, SS | 1 |
| Zakaria, MN | 1 |
| Abdel-Ghany, RH | 1 |
| Abdel-Rahman, AA | 1 |
| Mard, SA | 1 |
| Ahmadi, I | 1 |
| Ahangarpour, A | 1 |
| Gharib-Naseri, MK | 1 |
| Badavi, M | 1 |
| Feng, X | 1 |
| Tang, C | 1 |
| Geng, B | 1 |
| Qu, L | 1 |
| Yao, T | 1 |
| Gao, Y | 1 |
| Yao, X | 1 |
| Kang, K | 1 |
| Sun, L | 1 |
| Sun, X | 1 |
| Denizalti, M | 1 |
| Bozkurt, TE | 1 |
| Akpulat, U | 1 |
| Sahin-Erdemli, I | 1 |
| Abacıoğlu, N | 1 |
| Tang, G | 1 |
| Suzuki, K | 1 |
| Olah, G | 1 |
| Modis, K | 1 |
| Coletta, C | 1 |
| Kulp, G | 1 |
| Gerö, D | 1 |
| Szoleczky, P | 1 |
| Chang, T | 1 |
| Zhou, Z | 1 |
| Papapetropoulos, A | 1 |
| Szabo, C | 1 |
| Leng, X | 1 |
| Jia, J | 1 |
| Li, H | 1 |
| Zhang, X | 1 |
| Xue, R | 1 |
| Hao, DD | 1 |
| Sun, JP | 1 |
| Li, WW | 1 |
| Zhao, MM | 1 |
| Zhu, JH | 1 |
| Ding, YJ | 1 |
| Yusuf, M | 1 |
| Kwong Huat, BT | 1 |
| Hsu, A | 1 |
| Whiteman, M | 1 |
| Bhatia, M | 1 |
1 trial available for hydrogen sulfide and Alloxan Diabetes
| Article | Year |
|---|---|
[Effect of hydrogen sulfide on inducible nitric oxide synthase in kidneys of Type 1 diabetic rats].
Topics: Animals; Blotting, Western; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Hydrogen Sulfid | 2017 |
68 other studies available for hydrogen sulfide and Alloxan Diabetes
| Article | Year |
|---|---|
Alpha-lipoic acid treatment improves adverse cardiac remodelling in the diabetic heart - The role of cardiac hydrogen sulfide-synthesizing enzymes.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Hydr | 2022 |
Hydrogen Sulfide Improves Angiogenesis by Regulating the Transcription of pri-miR-126 in Diabetic Endothelial Cells.
Topics: Angiogenesis Inducing Agents; Animals; Diabetes Mellitus, Experimental; Glucose; Human Umbilical Vei | 2022 |
Hydrogen sulfide potentiates the favorable metabolic effects of inorganic nitrite in type 2 diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, | 2019 |
BDNF-TrkB pathway mediates antidepressant-like roles of H
Topics: Animals; Antidepressive Agents; Autophagy; Brain-Derived Neurotrophic Factor; Depression; Diabetes M | 2020 |
The role of activation of K
Topics: Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Diabetes Mellitus, Experimental; Diabetic | 2020 |
Hydrogen sulfide mitigates myocardial inflammation by inhibiting nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome activation in diabetic rats.
Topics: Animals; Carrier Proteins; Diabetes Mellitus, Experimental; Hydrogen Sulfide; Inflammasomes; Inflamm | 2020 |
Protective effect of intermediate doses of hydrogen sulfide against myocardial ischemia-reperfusion injury in obese type 2 diabetic rats.
Topics: Animals; Cardiotonic Agents; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High- | 2020 |
Protective effect of exogenous hydrogen sulfide on diaphragm muscle fibrosis in streptozotocin-induced diabetic rats.
Topics: Animals; Collagen; Cytokines; Diabetes Mellitus, Experimental; Diaphragm; Fibrosis; Hydrogen Sulfide | 2020 |
Exogenous hydrogen sulfide reduces atrial remodeling and atrial fibrillation induced by diabetes mellitus via activation of the PI3K/Akt/eNOS pathway.
Topics: Animals; Atrial Fibrillation; Cell Culture Techniques; Diabetes Mellitus, Experimental; Disease Mode | 2020 |
Modulation of hydrogen sulfide synthesis improves heart function and endothelium-dependent vasorelaxation in diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Hydrogen Sulfide; Nitric Oxide Synthase Type III; Oxidativ | 2021 |
[Effects of exogenous H
Topics: Animals; Diabetes Mellitus, Experimental; Fibrosis; Hydrogen Sulfide; Liver Cirrhosis; Male; Matrix | 2020 |
Hydrogen sulfide restores sevoflurane postconditioning mediated cardioprotection in diabetic rats: Role of SIRT1/Nrf2 signaling-modulated mitochondrial dysfunction and oxidative stress.
Topics: Animals; Cardiotonic Agents; Diabetes Mellitus, Experimental; Heme Oxygenase (Decyclizing); Hydrogen | 2021 |
Hydrogen Sulfide: A Potential Therapeutic Target in the Development of Diabetic Retinopathy.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Female; Fluorescent Antibody Techniq | 2020 |
Liraglutide restores late cardioprotective effects of remote preconditioning in diabetic rats via activation of hydrogen sulfide and nuclear factor erythroid 2-related factor 2 signaling pathway.
Topics: Animals; Diabetes Mellitus, Experimental; Hydrogen Sulfide; Ischemic Preconditioning; Ischemic Preco | 2021 |
Glucose-induced decrease of cystathionine β-synthase mediates renal injuries.
Topics: Animals; Cystathionine beta-Synthase; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gluco | 2021 |
Inhibition of farnesyl pyrophosphate synthase attenuates high glucose‑induced vascular smooth muscle cells proliferation.
Topics: Alendronate; Animals; Aorta; Blood Glucose; Cell Proliferation; Cells, Cultured; Chromatography, Hig | 2017 |
Exogenous Hydrogen Sulfide Ameliorates Diabetes-Associated Cognitive Decline by Regulating the Mitochondria-Mediated Apoptotic Pathway and IL-23/IL-17 Expression in db/db Mice.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cognitive Dysfunction; Diabetes Complications; Di | 2017 |
Hydrogen Sulfide As a Potential Target in Preventing Spermatogenic Failure and Testicular Dysfunction.
Topics: Animals; Diabetes Mellitus, Experimental; Humans; Hydrogen Sulfide; Infertility, Male; Male; Mice; M | 2018 |
Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats.
Topics: Animals; Autophagy; Autophagy-Related Proteins; Collagen Type IV; Diabetes Mellitus, Experimental; F | 2017 |
Effects of hydrogen sulfide on inducible nitric oxide synthase activity and expression of cardiomyocytes in diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Creatine Kinase, MB Form; Diabetes Mellitus, Experimental; Fast | 2017 |
Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway.
Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Endoplasmic Reticulu | 2018 |
[Protective effect of hydrogen sulfide on kidneys of type 1 diabetic rats].
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Urea Nitrogen; Caspase 3; Creatinine; Diabetes | 2016 |
Possible involvement of peripheral TRP channels in the hydrogen sulfide-induced hyperalgesia in diabetic rats.
Topics: Acetanilides; Analgesics; Animals; Capsaicin; Cystathionine beta-Synthase; Diabetes Mellitus, Experi | 2019 |
Effects of Hydrogen Sulfide on Carbohydrate Metabolism in Obese Type 2 Diabetic Rats.
Topics: Animals; Blood Glucose; Blood Pressure; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Di | 2019 |
Hydrogen sulfide preconditioning could ameliorate reperfusion associated injury in diabetic cardiomyopathy rat heart through preservation of mitochondria.
Topics: Animals; Cardiomyopathies; Diabetes Complications; Diabetes Mellitus, Experimental; Hydrogen Sulfide | 2019 |
Hydrogen sulfide attenuates lung ischemia-reperfusion injury through SIRT3-dependent regulation of mitochondrial function in type 2 diabetic rats.
Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Drug | 2019 |
Potassium channels contribute to the increased sensitivity of the rabbit carotid artery to hydrogen sulfide in diabetes.
Topics: Animals; Carotid Arteries; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hydrog | 2019 |
[Effects of hydrogen sulfide on renal fibrosis in diabetic rats and its mechanism].
Topics: Animals; Diabetes Mellitus, Experimental; Fibrosis; Hydrogen Sulfide; Male; Rats; Rats, Sprague-Dawl | 2018 |
H2S attenuates the myocardial fibrosis in diabetic rats through modulating PKC-ERK1/2MAPK signaling pathway.
Topics: Animals; Diabetes Mellitus, Experimental; Fibrosis; Hydrogen Sulfide; Male; MAP Kinase Signaling Sys | 2019 |
Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway.
Topics: Animals; Collagen; Diabetes Mellitus, Experimental; Fibrosis; Heart; Heart Diseases; Hydrogen Sulfid | 2019 |
EFFECTS OF 7-DAY MELATONIN INTRODUCTION ON THE HYDROGEN SULFIDE PRODUCTION AND GLUTATHIONE SYSTEM IN THE LIVER OF ALLOXAN INDUCED DIABETIC RATS.
Topics: Alloxan; Animals; Antioxidants; Diabetes Mellitus, Experimental; Glutathione; Hydrogen; Hydrogen Sul | 2019 |
Treatment with hydrogen sulfide alleviates streptozotocin-induced diabetic retinopathy in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Capillary Permeability; Cells, Cultu | 2013 |
Role of hydrogen sulfide in the pain processing of non-diabetic and diabetic rats.
Topics: Algorithms; Alkynes; Animals; Blood Glucose; Cystathionine gamma-Lyase; Cysteine; Data Interpretatio | 2013 |
H(2)S inhibits hyperglycemia-induced intrarenal renin-angiotensin system activation via attenuation of reactive oxygen species generation.
Topics: Acetophenones; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Blood Glucose; Cel | 2013 |
Increased protein aggregation in Zucker diabetic fatty rat brain: identification of key mechanistic targets and the therapeutic application of hydrogen sulfide.
Topics: Animals; Autophagy; Brain; Diabetes Mellitus, Experimental; Disease Models, Animal; Fibronectins; Gl | 2014 |
[Expressions of CSE and CBS in the penile corpus cavernosum of hyperglycemia rats and their implications].
Topics: Animals; Blood Pressure; Cystathionine gamma-Lyase; Diabetes Mellitus, Experimental; Electric Stimul | 2014 |
Hydrogen sulfide alleviates diabetic nephropathy in a streptozotocin-induced diabetic rat model.
Topics: Animals; Basement Membrane; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetic Nephropath | 2014 |
H2S donors attenuate diabetic nephropathy in rats: Modulation of oxidant status and polyol pathway.
Topics: Aldehyde Reductase; Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Nephropathies; | 2015 |
[Effect of hydrogen sulfide on myocardial fibrosis and expression of PKCα and HSP70 in diabetic rats].
Topics: Animals; Collagen Type III; Diabetes Mellitus, Experimental; Fibrosis; HSP70 Heat-Shock Proteins; Hy | 2015 |
Ginkgolide B increases hydrogen sulfide and protects against endothelial dysfunction in diabetic rats.
Topics: Acetylcholine; Animals; Cystathionine gamma-Lyase; Diabetes Mellitus, Experimental; Endothelium, Vas | 2015 |
Calcium sensing receptor regulating smooth muscle cells proliferation through initiating cystathionine-gamma-lyase/hydrogen sulfide pathway in diabetic rat.
Topics: Animals; Aorta, Thoracic; Benzamides; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; C | 2015 |
[Effects of hydrogen sulfide on myocardial fibrosis and MAPK1/3 and MMP-8 expression in diabetic rats].
Topics: Animals; Collagen Type I; Diabetes Mellitus, Experimental; Fibrosis; Hydrogen Sulfide; Injections, I | 2015 |
Antidepressant-like and anxiolytic-like effects of hydrogen sulfide in streptozotocin-induced diabetic rats through inhibition of hippocampal oxidative stress.
Topics: Aldehydes; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Blood Glucose; De | 2015 |
The protective effects of endogenous hydrogen sulfide modulator, S-propargyl-cysteine, on high glucose-induced apoptosis in cardiomyocytes: A novel mechanism mediated by the activation of Nrf2.
Topics: Animals; Antioxidants; Apoptosis; Blood Glucose; Cell Line; Cystathionine gamma-Lyase; Cysteine; Cyt | 2015 |
Cardiac H2S Generation Is Reduced in Ageing Diabetic Mice.
Topics: Aging; Animals; Cell Survival; Cells, Cultured; Cystathionine beta-Synthase; Cystathionine gamma-Lya | 2015 |
Exogenous Hydrogen Sulfide Attenuates Cardiac Fibrosis Through Reactive Oxygen Species Signal Pathways in Experimental Diabetes Mellitus Models.
Topics: Animals; Animals, Newborn; Diabetes Mellitus, Experimental; Fibroblasts; Gene Expression Regulation; | 2015 |
Hydrogen sulfide accelerates wound healing in diabetic rats.
Topics: Administration, Topical; Angiogenesis Inducing Agents; Animals; Anti-Inflammatory Agents; Antioxidan | 2015 |
Effects of hydrogen sulfide on myocardial fibrosis in diabetic rats: Changes in matrix metalloproteinases parameters.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Fibrosis; Heart; Hydrogen Sulfi | 2015 |
[Protective effects of hydrogen sulfide on diaphragmatic muscle of Type 1 diabetic rats and its anti-apoptotic mechanisms].
Topics: Animals; Apoptosis; Caspase 3; Diabetes Mellitus, Experimental; Diaphragm; Hydrogen Sulfide; Male; M | 2015 |
Effects of hydrogen sulfide on myocardial fibrosis and PI3K/AKT1-regulated autophagy in diabetic rats.
Topics: Animals; Autophagy; Biomarkers; Collagen Type I; Collagen Type II; Cystathionine gamma-Lyase; Diabet | 2016 |
Decreased Endogenous Hydrogen Sulfide Generation in Penile Tissues of Diabetic Rats with Erectile Dysfunction.
Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Diabetes Mellitus, Experi | 2016 |
Exogenous hydrogen sulphide ameliorates diabetic cardiomyopathy in rats by reversing disordered calcium-handling system in sarcoplasmic reticulum.
Topics: Animals; Calcium; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Disease Models, Animal | 2016 |
Novel hydrogen sulfide-releasing compound, S-propargyl-cysteine, prevents STZ-induced diabetic nephropathy.
Topics: Animals; Cell Proliferation; Cell Size; Cells, Cultured; Cysteine; Diabetes Mellitus, Experimental; | 2016 |
Cystathionine-γ lyase-derived hydrogen sulfide mediates the cardiovascular protective effects of moxonidine in diabetic rats.
Topics: Adiponectin; Alkynes; Animals; Baroreflex; Blood Glucose; Body Weight; Cardiotonic Agents; Cystathio | 2016 |
[Effect of hydrogen sulfide on cardiac myosin light chain kinase expression in diabetic rats].
Topics: Animals; Cardiotonic Agents; Creatine Kinase, MB Form; Diabetes Mellitus, Experimental; Heart; Hemod | 2016 |
[Effect of hydrogen sulfide on oxidative stress and endoplasmic reticulum stress in diabetic cardiomyopathy].
Topics: Animals; Apoptosis; Caspase 12; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Endoplas | 2016 |
[Effects of hydrogen sulfide on contraction capacity of diaphragm from type 1 diabetic rats].
Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Diaphragm; Hydrogen Sulfide; L-Lactate Dehydr | 2016 |
Delayed gastric emptying in diabetic rats caused by decreased expression of cystathionine gamma lyase and H
Topics: Animals; Cystathionine gamma-Lyase; Diabetes Mellitus, Experimental; Gastric Emptying; Gastroparesis | 2016 |
Exogenous H
Topics: Animals; Apoptosis; Blood Glucose; Blotting, Western; Cytochromes c; Diabetes Mellitus, Experimental | 2017 |
Hydrogen sulfide from adipose tissue is a novel insulin resistance regulator.
Topics: Adipose Tissue; Animals; Cystathionine gamma-Lyase; Diabetes Mellitus, Experimental; Fructose; Gluco | 2009 |
Rescue of mesangial cells from high glucose-induced over-proliferation and extracellular matrix secretion by hydrogen sulfide.
Topics: Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; Collagen Type IV; Diabetes Mellitus | 2011 |
The protective role of hydrogen sulfide in myocardial ischemia-reperfusion-induced injury in diabetic rats.
Topics: Alkynes; Animals; Apoptosis; Caspase 3; Diabetes Mellitus, Experimental; Down-Regulation; Enzyme Inh | 2011 |
The vasorelaxant effect of hydrogen sulfide is enhanced in streptozotocin-induced diabetic rats.
Topics: Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Hydrogen Sulfide; Hypoglycemic Agents; In | 2011 |
The pathogenic role of cystathionine γ-lyase/hydrogen sulfide in streptozotocin-induced diabetes in mice.
Topics: Animals; Apoptosis; Blood Glucose; Cell Line; Cell Survival; Cystathionine gamma-Lyase; Diabetes Mel | 2011 |
Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function.
Topics: Animals; Cell Line; Diabetes Mellitus, Experimental; Endothelial Cells; Endothelium, Vascular; Gluco | 2011 |
Exogenous hydrogen sulfide attenuates diabetic myocardial injury through cardiac mitochondrial protection.
Topics: Animals; Caspase 3; Cystathionine gamma-Lyase; Cytochromes c; Diabetes Mellitus, Experimental; Hydro | 2012 |
Hydrogen sulfide treatment promotes glucose uptake by increasing insulin receptor sensitivity and ameliorates kidney lesions in type 2 diabetes.
Topics: 3T3-L1 Cells; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; | 2013 |
Streptozotocin-induced diabetes in the rat is associated with enhanced tissue hydrogen sulfide biosynthesis.
Topics: Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Diabetes Mellitus, Experimental; Hy | 2005 |