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hydrogen carbonate and Rhabdomyolysis

hydrogen carbonate has been researched along with Rhabdomyolysis in 26 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Rhabdomyolysis: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.

Research Excerpts

ExcerptRelevanceReference
"A rhabdomyolysis protocol (RP) with mannitol and bicarbonate to prevent acute renal dysfunction (ARD, creatinine >2."7.85Bicarbonate and mannitol treatment for traumatic rhabdomyolysis revisited. ( de la Cruz, JS; Ellis, MK; Gao, X; Groat, T; Malinoski, DJ; Mullins, RJ; Nielsen, JS; Sally, M; Schreiber, M; Slater, M, 2017)
"Clinicians should be aware of the complications of rhabdomyolysis in patients who ingest doxylamine succinate and other over-the-counter antihistamines."7.68Severe rhabdomyolysis after doxylamine overdose. ( Miller, CH; Ognibere, AJ; Soto, LF, 1993)
"Treatment with procainamide not only inhibited the overexpression of DNMT1 but also diminished the overproduction of IL-6 in rhabdomyolysis rats."5.43Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats. ( Chen, SJ; Hii, HP; Ka, SM; Liao, MH; Shih, CC; Tsao, CM; Wu, CC, 2016)
" Positive urine tests (myoglobinuria, dipstick heme or protein ≥ 2+), high white cell count, lower serum bicarbonate on admission, and high peak serum CK were associated with development of AKI."4.02Acute kidney injury in pediatric non-traumatic rhabdomyolysis. ( Chan, WKY; Kuok, CI, 2021)
"A rhabdomyolysis protocol (RP) with mannitol and bicarbonate to prevent acute renal dysfunction (ARD, creatinine >2."3.85Bicarbonate and mannitol treatment for traumatic rhabdomyolysis revisited. ( de la Cruz, JS; Ellis, MK; Gao, X; Groat, T; Malinoski, DJ; Mullins, RJ; Nielsen, JS; Sally, M; Schreiber, M; Slater, M, 2017)
" Nine hospitalized patients had crush syndrome, and a prophylactic mannitol-bicarbonate cocktail was started in all at admission."3.74Early and intensive fluid replacement prevents acute renal failure in the crush cases associated with spontaneous collapse of an apartment in Konya. ( Ağca, E; Altintepe, L; Guney, I; Mazi, M; Tonbul, Z; Türk, S; Yeksan, M, 2007)
"A chart review between January 1992 and December 1995 was conducted of patients aged 18 years or older with a diagnosis of rhabdomyolysis and an initial serum creatine phosphokinase greater than 1000 U/L."3.73Factors predictive of acute renal failure and need for hemodialysis among ED patients with rhabdomyolysis. ( Bruno, GR; Chiang, WK; Fernandez, WG; Galea, S; Hung, O, 2005)
"Clinicians should be aware of the complications of rhabdomyolysis in patients who ingest doxylamine succinate and other over-the-counter antihistamines."3.68Severe rhabdomyolysis after doxylamine overdose. ( Miller, CH; Ognibere, AJ; Soto, LF, 1993)
"Rhabdomyolysis was present in 21."1.72Motor Vehicle Collision and Acute Kidney Injury in Children. ( Chan, WKY; Kuok, CI, 2022)
"But he developed acute kidney failure (AKF) and hemodialysis was performed."1.48Rhabdomyolysis following status epilepticus with hyperuricemia: A case report and literature review. ( Hong, S; Huang, H; Wang, L; Yang, M, 2018)
"Treatment with procainamide not only inhibited the overexpression of DNMT1 but also diminished the overproduction of IL-6 in rhabdomyolysis rats."1.43Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats. ( Chen, SJ; Hii, HP; Ka, SM; Liao, MH; Shih, CC; Tsao, CM; Wu, CC, 2016)
"Rhabdomyolysis is the disintegration of striated muscles resulting in the release of muscular cell contents into the extracellular fluid."1.34Rhabdomyolysis. ( Sever, MS, 2007)
"Administration of alkali, a treatment for rhabdomyolysis, improved renal function and significantly reduced the urinary excretion of F2-isoprostanes by approximately 80%."1.30A causative role for redox cycling of myoglobin and its inhibition by alkalinization in the pathogenesis and treatment of rhabdomyolysis-induced renal failure. ( Anand, R; Clozel, M; Cooper, CE; Darley-Usmar, V; Goodier, D; Holt, SG; Moore, KP; Morrow, JD; Patel, RP; Reeder, BJ; Roberts, LJ; Svistunenko, DA; Wilson, MT; Zackert, W, 1998)
"Rhabdomyolysis is usually known to the anaesthetist, who may be confronted with this acute, life-threatening complication during anaesthesia."1.27[Rhabdomyolysis as a late complication of anesthesia--a case of malignant hyperthermia?]. ( Abbrederis, K; Gattringer, C; Greil, R, 1985)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19906 (23.08)18.7374
1990's6 (23.08)18.2507
2000's4 (15.38)29.6817
2010's5 (19.23)24.3611
2020's5 (19.23)2.80

Authors

AuthorsStudies
Sawhney, JS1
Kasotakis, G1
Goldenberg, A1
Abramson, S1
Dodgion, C1
Patel, N1
Khan, M1
Como, JJ1
Kuok, CI2
Chan, WKY2
Valente-Acosta, B1
Moreno-Sanchez, F1
Fueyo-Rodriguez, O1
Palomar-Lever, A1
Buitendag, JJP1
Patel, MQ1
Variawa, S1
Fichardt, J1
Mostert, B1
Goliath, A1
Clarke, DL1
Oosthuizen, GV1
Leissinger, MK1
Johnson, JG1
Tully, TN1
Gaunt, SD1
Wang, L1
Hong, S1
Huang, H1
Yang, M1
Shih, CC1
Hii, HP1
Tsao, CM1
Chen, SJ1
Ka, SM1
Liao, MH1
Wu, CC1
Nielsen, JS1
Sally, M1
Mullins, RJ1
Slater, M1
Groat, T1
Gao, X1
de la Cruz, JS1
Ellis, MK1
Schreiber, M1
Malinoski, DJ1
Zhang, B1
Yang, G1
Yu, X1
Mao, H1
Xing, C1
Liu, J1
BORMAN, JB1
DAVIDSON, JT1
BLONDHEIM, SH1
Fernandez, WG1
Hung, O1
Bruno, GR1
Galea, S1
Chiang, WK1
Altintepe, L1
Guney, I1
Tonbul, Z1
Türk, S1
Mazi, M1
Ağca, E1
Yeksan, M1
Sever, MS1
Kellum, JA1
Cerda, J1
Kaplan, LJ1
Nadim, MK1
Palevsky, PM1
Soto, LF1
Miller, CH1
Ognibere, AJ1
Adlakha, A1
Lobl, J1
Prendergast, BD1
George, CF1
Górriz, JL1
Sancho, A1
Lopez-Martin, JM1
Alcoy, E1
Catalán, C1
Pallardó, LM1
Moore, KP1
Holt, SG1
Patel, RP1
Svistunenko, DA1
Zackert, W1
Goodier, D1
Reeder, BJ1
Clozel, M1
Anand, R1
Cooper, CE1
Morrow, JD1
Wilson, MT1
Darley-Usmar, V1
Roberts, LJ1
Kaukonen, L1
Hoffman, RS1
Os, I1
Jacobsen, D1
Enger, E1
Lie, B1
Ory, JP1
Guyon, B1
Robb, EJ1
Kronfeld, DS1
Wolf, AM1
Greil, R1
Gattringer, C1
Abbrederis, K1

Reviews

3 reviews available for hydrogen carbonate and Rhabdomyolysis

ArticleYear
Fluids for prevention and management of acute kidney injury.
    The International journal of artificial organs, 2008, Volume: 31, Issue:2

    Topics: Acute Kidney Injury; Animals; Bicarbonates; Colloids; Fluid Therapy; Hemofiltration; Hemoglobins; Hu

2008
A crack addict with extremely high creatine kinase levels.
    Hospital practice (Office ed.), 1993, Jun-15, Volume: 28, Issue:6

    Topics: Acute Kidney Injury; Adult; Bicarbonates; Crack Cocaine; Creatine Kinase; Humans; Infusions, Intrave

1993
Drug-induced rhabdomyolysis--mechanisms and management.
    Postgraduate medical journal, 1993, Volume: 69, Issue:811

    Topics: Acute Kidney Injury; Bicarbonates; Humans; Rhabdomyolysis; Risk Factors; Sodium; Sodium Bicarbonate

1993

Other Studies

23 other studies available for hydrogen carbonate and Rhabdomyolysis

ArticleYear
Management of rhabdomyolysis: A practice management guideline from the Eastern Association for the Surgery of Trauma.
    American journal of surgery, 2022, Volume: 224, Issue:1 Pt A

    Topics: Acute Kidney Injury; Bicarbonates; Humans; Mannitol; Meta-Analysis as Topic; Practice Management; Re

2022
Motor Vehicle Collision and Acute Kidney Injury in Children.
    Pediatric emergency care, 2022, Oct-01, Volume: 38, Issue:10

    Topics: Acute Kidney Injury; Bicarbonates; Child; Creatine Kinase; Humans; Motor Vehicles; Retrospective Stu

2022
Rhabdomyolysis as an initial presentation in a patient diagnosed with COVID-19.
    BMJ case reports, 2020, Jun-24, Volume: 13, Issue:6

    Topics: Aged; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Anticoagulants; Azithromycin; Betaco

2020
Acute kidney injury in pediatric non-traumatic rhabdomyolysis.
    Pediatric nephrology (Berlin, Germany), 2021, Volume: 36, Issue:10

    Topics: Acute Kidney Injury; Bicarbonates; Child; Creatine Kinase; Heme; Humans; Myoglobinuria; Retrospectiv

2021
Venous bicarbonate and creatine kinase as diagnostic and prognostic tools in the setting of acute traumatic rhabdomyolysis.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2021, Mar-31, Volume: 111, Issue:4

    Topics: Acute Kidney Injury; Adult; Bicarbonates; Biomarkers; Creatine Kinase; Creatinine; Crush Syndrome; F

2021
Rhabdomyolysis and Artifactual Increase in Plasma Bicarbonate Concentration in an Amazon Parrot (Amazona species).
    Journal of avian medicine and surgery, 2017, Volume: 31, Issue:3

    Topics: Acid-Base Equilibrium; Amazona; Animals; Anti-Inflammatory Agents, Non-Steroidal; Artifacts; Bicarbo

2017
Rhabdomyolysis following status epilepticus with hyperuricemia: A case report and literature review.
    Medicine, 2018, Volume: 97, Issue:26

    Topics: Acute Kidney Injury; Bicarbonates; Humans; Hyperuricemia; Male; Renal Dialysis; Rhabdomyolysis; Risk

2018
Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Acidosis; Animals; Bicarbonates; Biomarkers; Creatinine; DNA (Cytosine-5-)-Methyltransferase 1; DNA

2016
Bicarbonate and mannitol treatment for traumatic rhabdomyolysis revisited.
    American journal of surgery, 2017, Volume: 213, Issue:1

    Topics: Acute Kidney Injury; Adult; Algorithms; Bicarbonates; Clinical Protocols; Creatine Kinase; Databases

2017
Haff disease after eating crayfish in east China.
    Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:5

    Topics: Adult; Animals; Astacoidea; Bicarbonates; China; Eating; Female; Fluid Therapy; Follow-Up Studies; H

2012
IDIOPATHIC RHABDOMYOLYSIS (MYOGLOBINURIA) AS AN ACUTE RESPIRATORY PROBLEM.
    British medical journal, 1963, Sep-21, Volume: 2, Issue:5359

    Topics: Bicarbonates; Heart Arrest; Heart Massage; Myoglobin; Myoglobinuria; Positive-Pressure Respiration;

1963
Factors predictive of acute renal failure and need for hemodialysis among ED patients with rhabdomyolysis.
    The American journal of emergency medicine, 2005, Volume: 23, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Bicarbonates; Blood Urea Nitrogen; Calcium; Comorbidit

2005
Early and intensive fluid replacement prevents acute renal failure in the crush cases associated with spontaneous collapse of an apartment in Konya.
    Renal failure, 2007, Volume: 29, Issue:6

    Topics: Acute Kidney Injury; Adolescent; Adult; Bicarbonates; Child; Crush Syndrome; Disasters; Female; Flui

2007
Rhabdomyolysis.
    Acta clinica Belgica, 2007, Volume: 62 Suppl 2

    Topics: Acute Kidney Injury; Aged; Bicarbonates; Compartment Syndromes; Crush Syndrome; Diuretics, Osmotic;

2007
Severe rhabdomyolysis after doxylamine overdose.
    Postgraduate medicine, 1993, Volume: 93, Issue:8

    Topics: Adult; Bicarbonates; Creatine Kinase; Doxylamine; Drug Overdose; Epilepsy, Tonic-Clonic; Histamine H

1993
Rhabdomyolysis and acute renal failure associated with gemfibrozil therapy.
    Nephron, 1996, Volume: 74, Issue:2

    Topics: Acute Kidney Injury; Aged; Angiotensin-Converting Enzyme Inhibitors; Bicarbonates; Diabetes Mellitus

1996
A causative role for redox cycling of myoglobin and its inhibition by alkalinization in the pathogenesis and treatment of rhabdomyolysis-induced renal failure.
    The Journal of biological chemistry, 1998, Nov-27, Volume: 273, Issue:48

    Topics: Animals; Bicarbonates; Dinoprost; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Glyc

1998
Cocaine.
    New York state journal of medicine, 1990, Volume: 90, Issue:1

    Topics: Acidosis; Ammonium Chloride; Bicarbonates; Cocaine; Dantrolene; Humans; Malignant Hyperthermia; Rhab

1990
[Forced alkalic diuresis. Still a current therapy in poisoning].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1989, Aug-10, Volume: 109, Issue:22

    Topics: Bicarbonates; Diuresis; Humans; Poisoning; Rhabdomyolysis; Sodium; Sodium Bicarbonate

1989
[Acute renal insufficiency caused by rhabdomyolysis. Etiopathogenetic and therapeutic aspects].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1985, Nov-26, Volume: 74, Issue:48

    Topics: Acute Kidney Injury; Bicarbonates; Dopamine; Furosemide; Humans; Rhabdomyolysis; Sodium; Sodium Bica

1985
Dietary sodium bicarbonate as a treatment for exertional rhabdomyolysis in a horse.
    Journal of the American Veterinary Medical Association, 1986, Mar-15, Volume: 188, Issue:6

    Topics: Animals; Aspartate Aminotransferases; Bicarbonates; Blood Glucose; Creatine Kinase; Diet; Female; Ho

1986
Dietary sodium bicarbonate for exertional rhabdomyolysis.
    Journal of the American Veterinary Medical Association, 1986, Jun-01, Volume: 188, Issue:11

    Topics: Animals; Bicarbonates; Horse Diseases; Horses; Physical Exertion; Rhabdomyolysis; Sodium; Sodium Bic

1986
[Rhabdomyolysis as a late complication of anesthesia--a case of malignant hyperthermia?].
    Wiener klinische Wochenschrift, 1985, Nov-08, Volume: 97, Issue:21

    Topics: Adult; Allopurinol; Ampicillin; Anesthesia; Bicarbonates; Humans; Male; Malignant Hyperthermia; Pota

1985