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hydrogen carbonate and Reperfusion Injury

hydrogen carbonate has been researched along with Reperfusion Injury in 26 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"St Thomas cardioplegia solution supplemented with emulsified isoflurane enhanced its cardioprotection in an isolated heart ischemia reperfusion injury model in rats."7.76Cardioprotection afforded by St Thomas solution is enhanced by emulsified isoflurane in an isolated heart ischemia reperfusion injury model in rats. ( Huang, H; Li, T; Liu, J; Liu, S; Yanfang, C; Zhang, W, 2010)
"Metabolic acidosis was induced in male Wistar rats by ingesting ammonium chloride (NH4Cl) in tap water, beginning 2 days before ischemic insult and maintained during the entire study."3.83Metabolic acidosis aggravates experimental acute kidney injury. ( da Silva, MT; de Brito, TS; de Menezes, DB; dos Santos, AA; Freire, RS; Libório, AB; Magalhães, PA; Martins, AM; Vale, ML, 2016)
"St Thomas cardioplegia solution supplemented with emulsified isoflurane enhanced its cardioprotection in an isolated heart ischemia reperfusion injury model in rats."3.76Cardioprotection afforded by St Thomas solution is enhanced by emulsified isoflurane in an isolated heart ischemia reperfusion injury model in rats. ( Huang, H; Li, T; Liu, J; Liu, S; Yanfang, C; Zhang, W, 2010)
"Reperfusion injury was not affected by DIDS or HEPES but was attenuated by hypoxia."1.31Vascular release of nonheme iron in perfused rabbit lungs. ( Ghio, AJ; Huang, YT; Nozik-Grayck, E; Piantadosi, CA, 2001)
"Tirilazad attenuates cerebral edema and improves somatosensory evoked potential recovery after incomplete ischemia associated with severe acidosis."1.29Effect of the 21-aminosteroid tirilazad on cerebral pH and somatosensory evoked potentials after incomplete ischemia. ( Blizzard, KK; Kirsch, JR; Koehler, RC; Maruki, Y; Traystman, RJ, 1993)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (38.46)18.2507
2000's8 (30.77)29.6817
2010's7 (26.92)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Lu, M1
Jia, M1
Wang, Q1
Guo, Y1
Li, C1
Ren, B1
Qian, F1
Wu, J1
Magalhães, PA1
de Brito, TS1
Freire, RS1
da Silva, MT1
dos Santos, AA1
Vale, ML1
de Menezes, DB1
Martins, AM1
Libório, AB1
Najafi, H1
Owji, SM1
Kamali-Sarvestani, E1
Moosavi, SM1
Nielsen, PM1
Laustsen, C1
Bertelsen, LB1
Qi, H1
Mikkelsen, E1
Kristensen, ML1
Nørregaard, R1
Stødkilde-Jørgensen, H1
Queliconi, BB2
Kowaltowski, AJ2
Gottlieb, RA1
Kato, N1
Abe, S1
Suto, M1
Hiraiwa, K1
Huang, H1
Zhang, W1
Liu, S1
Yanfang, C1
Li, T1
Liu, J1
deFoneska, A1
Kaunitz, JD1
Marazzi, TB1
Vaz, SM1
Brookes, PS1
Nehrke, K1
Augusto, O1
Koksal, C1
Bozkurt, AK1
Cangel, U1
Ustundag, N1
Konukoglu, D1
Musellim, B1
Sayin, AG1
Zinchuk, VV1
Khodosovsky, MN1
Maslakov, DA1
Hirt, SW1
Wahlers, T1
Jurmann, M1
Dammenhayn, L1
Rohde, R1
Haverich, A1
Drossos, G1
Lazou, A1
Panagopoulos, P1
Westaby, S1
Takoudes, TG1
Amirhamzeh, MM1
Hsu, DT1
Wise, BR1
Odeh, SO1
Spotnitz, HM1
Lennon, GM1
Ryan, PC1
Fitzpatrick, JM1
O'Neill, PJ1
Cobb, LM1
Steigman, CK1
Chaudry, IH1
Maruki, Y2
Koehler, RC2
Eleff, SM1
Traystman, RJ2
Kirsch, JR1
Blizzard, KK1
Selim Isbir, C1
Doğan, R1
Farsak, B1
Aydin, M1
Kilinç, K1
Ducko, CT1
Stephenson, ER1
Jayawant, AM1
Vigilance, DW1
Damiano, RJ1
Featherstone, RL1
Chambers, DJ1
Kelly, FJ1
Huang, YT1
Ghio, AJ1
Nozik-Grayck, E1
Piantadosi, CA1
Kim, YI1
Kawano, K1
Goto, S1
Yoshida, T1
Kamada, N1
Heijnen, BH1
Elkhaloufi, Y1
Straatsburg, IH1
Van Gulik, TM1
Mankad, PS1
Chester, AH1
Yacoub, MH1
Montgomery, A1
Borgström, A1
Haglund, U1

Reviews

2 reviews available for hydrogen carbonate and Reperfusion Injury

ArticleYear
The electrogenic sodium bicarbonate cotransporter and its roles in the myocardial ischemia-reperfusion induced cardiac diseases.
    Life sciences, 2021, Apr-01, Volume: 270

    Topics: Acidosis; Animals; Astrocytes; Bicarbonates; Coronary Artery Disease; Heart; Heart Diseases; Humans;

2021
Gastroduodenal mucosal defense.
    Current opinion in gastroenterology, 2010, Volume: 26, Issue:6

    Topics: Alkaline Phosphatase; Amino Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bicarbonates; G

2010

Trials

1 trial available for hydrogen carbonate and Reperfusion Injury

ArticleYear
Deferoxamine cardioplegia reduces superoxide radical production in human myocardium.
    The Annals of thoracic surgery, 1995, Volume: 59, Issue:1

    Topics: Aged; Bicarbonates; Calcium Chloride; Cardiac Surgical Procedures; Cardioplegic Solutions; Deferoxam

1995

Other Studies

23 other studies available for hydrogen carbonate and Reperfusion Injury

ArticleYear
Metabolic acidosis aggravates experimental acute kidney injury.
    Life sciences, 2016, Feb-01, Volume: 146

    Topics: Acidosis; Acute Kidney Injury; Ammonium Chloride; Animals; Bicarbonates; Heme Oxygenase (Decyclizing

2016
A1 -Adenosine receptor activation has biphasic roles in development of acute kidney injury at 4 and 24 h of reperfusion following ischaemia in rats.
    Experimental physiology, 2016, 07-01, Volume: 101, Issue:7

    Topics: Acute Kidney Injury; Animals; Apoptosis; Bicarbonates; Cell Movement; Cytokines; Hemodynamics; Infla

2016
In situ lactate dehydrogenase activity: a novel renal cortical imaging biomarker of tubular injury?
    American journal of physiology. Renal physiology, 2017, 03-01, Volume: 312, Issue:3

    Topics: Acute Kidney Injury; Alanine; Animals; Bicarbonates; Biomarkers; Carbon Isotopes; Disease Models, An

2017
Bicarbonate Increases Ischemia-Reperfusion Damage by Inhibiting Mitophagy.
    PloS one, 2016, Volume: 11, Issue:12

    Topics: Animals; Autophagy; Bicarbonates; Cells, Cultured; Male; Microtubule-Associated Proteins; Mitochondr

2016
Comparison of renal dysfunction in wild-type, IL-6 KO and iNOS KO mice hind limb tourniquet-reperfusion model.
    Legal medicine (Tokyo, Japan), 2009, Volume: 11 Suppl 1

    Topics: Acidosis; Animals; Bicarbonates; Blood Urea Nitrogen; Carbon Dioxide; Erythrocytes; Forensic Patholo

2009
Cardioprotection afforded by St Thomas solution is enhanced by emulsified isoflurane in an isolated heart ischemia reperfusion injury model in rats.
    Journal of cardiothoracic and vascular anesthesia, 2010, Volume: 24, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Creatine K

2010
Bicarbonate modulates oxidative and functional damage in ischemia-reperfusion.
    Free radical biology & medicine, 2013, Volume: 55

    Topics: Animals; Bicarbonates; Buffers; Caenorhabditis elegans; Carbon Dioxide; Cell Survival; Cells, Cultur

2013
Attenuation of ischemia/reperfusion injury by N-acetylcysteine in a rat hind limb model.
    The Journal of surgical research, 2003, May-15, Volume: 111, Issue:2

    Topics: Acetylcysteine; Animals; Bicarbonates; Constriction; Creatine Kinase; Dimethyl Sulfoxide; Disease Mo

2003
Influence of different oxygen modes on the blood oxygen transport and prooxidant-antioxidant status during hepatic ischemia/reperfusion.
    Physiological research, 2003, Volume: 52, Issue:5

    Topics: Alanine Transaminase; alpha-Tocopherol; Animals; Antioxidants; Aspartate Aminotransferases; Bicarbon

2003
Antagonisation of platelet activating factor--a new therapeutic concept for improvement of organ quality in lung preservation.
    Transplant international : official journal of the European Society for Organ Transplantation, 1992, Volume: 5 Suppl 1

    Topics: Animals; Bicarbonates; Blood Pressure; Calcium Chloride; Cardioplegic Solutions; Dogs; Heart; Heart-

1992
Time course of perfusion-induced myocardial edema resolution in rats.
    The Journal of surgical research, 1994, Volume: 57, Issue:6

    Topics: Animals; Bicarbonates; Body Water; Calcium Chloride; Disease Models, Animal; Edema, Cardiac; Magnesi

1994
Ischaemia-reperfusion injury in the rat kidney: effect of a single dose of sodium bicarbonate.
    The British journal of surgery, 1993, Volume: 80, Issue:1

    Topics: Animals; Bicarbonates; Hydrogen-Ion Concentration; Injections, Intravenous; Ischemia; Kidney; Kidney

1993
Prevention of secondary cardiovascular instability after intestinal ischemia and reperfusion improves survival.
    The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 2

    Topics: Acidosis; Animals; Bicarbonates; Blood Pressure; Body Water; Cardiovascular Diseases; Fluid Therapy;

1993
Intracellular pH during reperfusion influences evoked potential recovery after complete cerebral ischemia.
    Stroke, 1993, Volume: 24, Issue:5

    Topics: Acetazolamide; Acidosis; Animals; Bicarbonates; Brain Ischemia; Carbon Dioxide; Cytoplasm; Dogs; Evo

1993
Effect of the 21-aminosteroid tirilazad on cerebral pH and somatosensory evoked potentials after incomplete ischemia.
    Stroke, 1993, Volume: 24, Issue:5

    Topics: Acidosis; Adenosine Triphosphate; Animals; Bicarbonates; Brain; Brain Edema; Brain Ischemia; Cytopla

1993
The protective effect of lisinopril on membrane-bound enzymes in myocardial preservation.
    Cell biochemistry and function, 2000, Volume: 18, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bicarbonates; Calcium Chloride; Calcium-Transport

2000
Potassium channel openers: are they effective as pretreatment or additives to cardioplegia?
    The Annals of thoracic surgery, 2000, Volume: 69, Issue:5

    Topics: Animals; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Coronary Circulation; Female; Magne

2000
Comparison of phosphodiesterase inhibitors of differing isoenzyme selectivity added to St. Thomas' hospital cardioplegic solution used for hypothermic preservation of rat lungs.
    American journal of respiratory and critical care medicine, 2000, Volume: 162, Issue:3 Pt 1

    Topics: Animals; Bicarbonates; Calcium Chloride; Hypothermia, Induced; Lung; Lung Transplantation; Magnesium

2000
Vascular release of nonheme iron in perfused rabbit lungs.
    American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 280, Issue:3

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anion Exchange Protein 1, Erythrocyte; Bi

2001
Efficacy of prostacyclin analogue (OP-2507) in viable hepatic grafts from pigs with non-beating hearts.
    Transplant international : official journal of the European Society for Organ Transplantation, 1994, Volume: 7 Suppl 1

    Topics: Animals; Bicarbonates; Bile; Epoprostenol; Female; Graft Survival; Heart Arrest, Induced; Hypertonic

1994
Influence of acidosis and hypoxia on liver ischemia and reperfusion injury in an in vivo rat model.
    Journal of applied physiology (Bethesda, Md. : 1985), 2002, Volume: 93, Issue:1

    Topics: Acidosis; Anesthesia; Animals; Bicarbonates; Blood Gas Analysis; Blood Pressure; Carbon Dioxide; Hyp

2002
Ischaemic endothelial dysfunction after single or multidose cardioplegia.
    European heart journal, 1992, Volume: 13, Issue:7

    Topics: Animals; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Coronary Circulation; Coronary Dise

1992
Pancreatic proteases and intestinal mucosal injury after ischemia and reperfusion in the pig.
    Gastroenterology, 1992, Volume: 102, Issue:1

    Topics: Animals; Arteries; Bicarbonates; Carbon Dioxide; Endopeptidases; Female; Hemodynamics; Hydrogen-Ion

1992