hydrogen carbonate has been researched along with Phenylketonurias in 4 studies
Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.
Phenylketonurias: A group of autosomal recessive disorders marked by a deficiency of the hepatic enzyme PHENYLALANINE HYDROXYLASE or less frequently by reduced activity of DIHYDROPTERIDINE REDUCTASE (i.e., atypical phenylketonuria). Classical phenylketonuria is caused by a severe deficiency of phenylalanine hydroxylase and presents in infancy with developmental delay; SEIZURES; skin HYPOPIGMENTATION; ECZEMA; and demyelination in the central nervous system. (From Adams et al., Principles of Neurology, 6th ed, p952).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Low-dose continuous infusions of [2H5]phenylalanine, [1-13C]propionate, and [1-13C]leucine were used to quantitate phenylalanine hydroxylation in phenylketonuria (PKU, four subjects), propionate oxidation in methylmalonic acidaemia (MMA, four subjects), and propionic acidaemia (PA, four subjects) and leucine oxidation in maple syrup urine disease (MSUD, four subjects)." | 3.68 | In vivo enzyme activity in inborn errors of metabolism. ( Halliday, D; Leonard, JV; Thompson, GN; Walter, JH, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| PASIEKA, AE | 1 |
| THOMAS, ME | 1 |
| LOGAN, JE | 1 |
| ALLEN, RH | 1 |
| Thompson, GN | 1 |
| Walter, JH | 1 |
| Leonard, JV | 1 |
| Halliday, D | 1 |
| Patel, MS | 2 |
| Grover, WD | 1 |
| Auerbach, VH | 1 |
4 other studies available for hydrogen carbonate and Phenylketonurias
| Article | Year |
|---|---|
SPECIFIC DETECTION OF PHENYLALANINE FOLLOWING CHROMATOGRAPHIC SEPARATION FROM SERUM AND URINE OF PHENYLKETONURIC.
Topics: Amino Acid Metabolism, Inborn Errors; Bicarbonates; Blood Chemical Analysis; Chromatography; Humans; | 1964 |
In vivo enzyme activity in inborn errors of metabolism.
Topics: Adult; Bicarbonates; Carbon Isotopes; Child; Child, Preschool; Deuterium; Female; Humans; Hydroxylat | 1990 |
The effect of phenylpyruvate on pyruvate metabolism in rat brain.
Topics: Animals; Bicarbonates; Brain; Carbon Isotopes; Culture Media; Freeze Drying; Humans; In Vitro Techni | 1972 |
Pyruvate metabolism by homogenates of human brain: effects of phenylpyruvate and implications for the etiology of the mental retardation in phenylketonuria.
Topics: Bicarbonates; Brain; Carbon Isotopes; Decarboxylation; Humans; In Vitro Techniques; Intellectual Dis | 1973 |