hydrogen carbonate has been researched along with Pain in 63 studies
Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of pH adjustment of mepivacaine on the incidence of tourniquet pain during axillary brachial plexus anaesthesia was studied." | 9.07 | pH adjustment of mepivacaine decreases the incidence of tourniquet pain during axillary brachial plexus anaesthesia. ( Tetzlaff, JE; Walsh, M; Yoon, HJ, 1993) |
| "In an attempt to determine whether penile pain associated with intracorporeal injections could be due to the acidity of the medication, we performed a randomized study comparing the incidence of penile pain following intracorporeal injections with or without the addition of sodium bicarbonate to the intracorporeal medications." | 9.07 | Sodium bicarbonate alleviates penile pain induced by intracavernous injections for erectile dysfunction. ( Moriel, EZ; Rajfer, J, 1993) |
| "Pain on injection of lidocaine is often considered a necessary evil, but it can be reduced by simple means." | 8.95 | Reduced pain when injecting lidocaine. ( Finsen, V, 2017) |
| "Two patients with acute pancreatitis had pronounced relief of epigastric pain associated with falls in plasma amylase after intravenous glucagon." | 5.25 | Possible use of glucagon in the treatment of pancreatitis. ( Condon, JR; Knight, MJ; Smith, R, 1971) |
| " The network meta-analysis revealed that "bicarbonate-buffered lidocaine with epinephrine" led to a significant decrease in injection pain (preference question) compared to "prilocaine with felypressin" and "lidocaine with epinephrine," whereas no significant differences were detected in the analysis of injection pain measured using the VAS." | 5.22 | Patient Comfort with Various Local Infiltration Anesthetics for Minor Oculoplastic Surgery: A Systematic Review and Network Meta-Analysis. ( Chen, C; Chiu, WK; Kang, YN; Liou, CM; Liu, HM; Wu, TJ, 2022) |
| "Eleven homosexual men were studied to evaluate the efficacy and pain associated with intralesional vinblastine with or without 1% bicarbonate buffered lidocaine (BBL)." | 5.07 | Intralesional vinblastine for cutaneous Kaposi's sarcoma associated with acquired immunodeficiency syndrome. A clinical trial to evaluate efficacy and discomfort associated with infection. ( Bason, MM; Berger, TG; Boudreaux, AA; Cosby, CD; Smith, LL; Tappero, JW, 1993) |
| "To test whether buffered lidocaine is less painful to administer as a digital nerve block than plain lidocaine." | 5.07 | Buffered versus plain lidocaine for digital nerve blocks. ( Bartfield, JM; Ford, DT; Homer, PJ, 1993) |
| "The effect of pH adjustment of mepivacaine on the incidence of tourniquet pain during axillary brachial plexus anaesthesia was studied." | 5.07 | pH adjustment of mepivacaine decreases the incidence of tourniquet pain during axillary brachial plexus anaesthesia. ( Tetzlaff, JE; Walsh, M; Yoon, HJ, 1993) |
| "To compare the degree of pain of intradermal infiltration and the duration of anesthesia for 1% lidocaine with epinephrine 1:100,000, 1% lidocaine with epinephrine 1:100,000 with 80 meq/L sodium bicarbonate, bacteriostatic saline solution with 1% lidocaine with epinephrine 1:300,000, and bacteriostatic saline solution with 1% lidocaine with epinephrine 1:100,000." | 5.07 | Less painful alternatives for local anesthesia. ( Lugo-Janer, G; Padial, M; Sánchez, JL, 1993) |
| "In an attempt to determine whether penile pain associated with intracorporeal injections could be due to the acidity of the medication, we performed a randomized study comparing the incidence of penile pain following intracorporeal injections with or without the addition of sodium bicarbonate to the intracorporeal medications." | 5.07 | Sodium bicarbonate alleviates penile pain induced by intracavernous injections for erectile dysfunction. ( Moriel, EZ; Rajfer, J, 1993) |
| "The authors propose that pH buffering of bupivicaine with sodium bicarbonate reduces the pain associated with its local subcutaneous infiltration." | 5.07 | The effect of pH buffering on reducing the pain associated with subcutaneous infiltration of bupivicaine. ( Cheney, PR; Molzen, G; Tandberg, D, 1991) |
| "A double-masked, randomized clinical trial was conducted to determine if subcutaneous eyelid injections of a bicarbonate-buffered lidocaine-epinephrine-hyaluronidase mixture were less painful than unbuffered injections." | 5.06 | Bicarbonate-buffered lidocaine-epinephrine-hyaluronidase for eyelid anesthesia. ( Eccarius, SG; Gordon, ME; Parelman, JJ, 1990) |
| "The effects of pH buffering on the pain of administration and efficacy of three local anesthetics (1% lidocaine, 1% lidocaine with 1:100,000 epinephrine, and 1% mepivacaine) were investigated in a randomized, prospective, double-blind study of 25 adult volunteers." | 5.06 | Pain reduction in local anesthetic administration through pH buffering. ( Begalla, K; Buchanan, L; Christoph, RA; Schwartz, S, 1988) |
| "Pain on injection of lidocaine is often considered a necessary evil, but it can be reduced by simple means." | 4.95 | Reduced pain when injecting lidocaine. ( Finsen, V, 2017) |
| "The pain usually associated with intradermal injection of lidocaine and epinephrine is significantly attenuated by the addition of either sodium bicarbonate or sodium hydroxide to 1% lidocaine with epinephrine." | 3.68 | Neutralized lidocaine with epinephrine for local anesthesia--II. ( Chinn, SE; Cole, GW; Klein, JA; Stewart, JH, 1990) |
| "Pain was assessed on a visual analogue scale and a verbal rating scale." | 2.90 | Efficacy of buffered local anaesthetics in head and neck infections. ( Arora, G; Dasukil, S; Degala, S, 2019) |
| "Pain was assessed using a verbal rating scale and the validated McGill Pain Questionnaire (MPQ)." | 2.69 | Bicarbonate and bicarbonate/lactate peritoneal dialysis solutions for the treatment of infusion pain. ( Berglund, J; Faict, D; Gokal, R; Gröntoft, KC; Larsson, R; Lindbergh, M; Mactier, RA; Naik, RB; Sprosen, TS; Tranaeus, AP; Williams, PF; Wrege, U, 1998) |
| "Incidences of arrhythmia, muscular cramps and headache were significantly less frequent during HF." | 2.68 | On-line predilution hemofiltration versus ultrapure high-flux hemodialysis: a multicenter prospective study in 23 patients. Sardinian Collaborative Study Group of On-Line Hemofiltration. ( Altieri, P; Asproni, E; Bolasco, F; Bolasco, PG; Bostrom, M; Cabiddu, GF; Cadinu, F; Casu, D; Cossu, M; Ferrara, R; Ganadu, M; Passaghe, M; Pinna, M; Sorba, GB, 1997) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) can be challenging to treat due to pain with wound care and ongoing fluid loss." | 1.43 | The use of porcine xenografts in patients with toxic epidermal necrolysis. ( Gondek, SP; Kahn, SA; Rae, L; Summitt, JB; Thayer, WP; Troche, M; Young, JB, 2016) |
| "Two patients with acute pancreatitis had pronounced relief of epigastric pain associated with falls in plasma amylase after intravenous glucagon." | 1.25 | Possible use of glucagon in the treatment of pancreatitis. ( Condon, JR; Knight, MJ; Smith, R, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (50.79) | 18.7374 |
| 1990's | 20 (31.75) | 18.2507 |
| 2000's | 5 (7.94) | 29.6817 |
| 2010's | 3 (4.76) | 24.3611 |
| 2020's | 3 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Futagami, S | 1 |
| Wakabayashi, M | 1 |
| Liu, HM | 1 |
| Wu, TJ | 1 |
| Liou, CM | 1 |
| Chiu, WK | 1 |
| Kang, YN | 1 |
| Chen, C | 1 |
| Hytönen, M | 1 |
| Nietosvaara, Y | 1 |
| Reito, A | 1 |
| Sirola, J | 1 |
| Heikkinen, N | 1 |
| Savolainen, A | 1 |
| Räisänen, MP | 1 |
| Arora, G | 1 |
| Degala, S | 1 |
| Dasukil, S | 1 |
| Finsen, V | 1 |
| Young, JB | 1 |
| Gondek, SP | 1 |
| Troche, M | 1 |
| Summitt, JB | 1 |
| Rae, L | 1 |
| Thayer, WP | 1 |
| Kahn, SA | 1 |
| MacPherson, R | 1 |
| SCHWARTZ, E | 1 |
| MCELFRESH, AE | 1 |
| BONNET, P | 1 |
| LEROUX, C | 1 |
| TASEI, LA | 1 |
| ROY, JC | 1 |
| THUAU, F | 1 |
| VITSE, M | 1 |
| JULOU, L | 1 |
| DUCROT, R | 1 |
| BARDONE, MC | 1 |
| DETAILLE, Y | 1 |
| GUYONNET, JC | 1 |
| LOISEAU, G | 1 |
| MYON, J | 1 |
| PASQUET, J | 1 |
| WOOD, TJ | 1 |
| Lameire, N | 1 |
| Pecoits-Filho, R | 1 |
| Tranaeus, A | 1 |
| Lindholm, B | 1 |
| Dratwa, M | 1 |
| Wilkie, M | 1 |
| Ryckelynck, JP | 1 |
| ter Wee, PM | 1 |
| Rutherford, P | 1 |
| Michel, C | 1 |
| Hopwood, A | 1 |
| Curtis, L | 1 |
| Denys, N | 1 |
| Divino Filho, JC | 1 |
| Faict, D | 2 |
| Ball, EL | 1 |
| Sanjay, P | 1 |
| Woodward, A | 1 |
| Walan, A | 1 |
| Chevrel, B | 1 |
| Joffe, SN | 1 |
| Primrose, JN | 1 |
| Bristol, DG | 1 |
| Zucchelli, P | 1 |
| Santoro, A | 1 |
| Spongano, M | 1 |
| Kuno, T | 1 |
| Kikuchi, F | 1 |
| Yanai, M | 1 |
| Nagura, Y | 1 |
| Takahashi, S | 1 |
| Gilger, MA | 1 |
| Wagner, ML | 1 |
| Barrish, JO | 1 |
| McCarroll, LR | 1 |
| Healy, WM | 1 |
| Boudreaux, AA | 1 |
| Smith, LL | 1 |
| Cosby, CD | 1 |
| Bason, MM | 1 |
| Tappero, JW | 1 |
| Berger, TG | 1 |
| Bartfield, JM | 1 |
| Ford, DT | 1 |
| Homer, PJ | 1 |
| Tetzlaff, JE | 2 |
| Walsh, M | 2 |
| Yoon, HJ | 2 |
| Lugo-Janer, G | 1 |
| Padial, M | 1 |
| Sánchez, JL | 1 |
| Moriel, EZ | 1 |
| Rajfer, J | 1 |
| Fonseca, V | 1 |
| Hinson, J | 1 |
| Pappas, A | 1 |
| Waner, M | 1 |
| Flock, S | 1 |
| Altieri, P | 1 |
| Sorba, GB | 1 |
| Bolasco, PG | 1 |
| Bostrom, M | 1 |
| Asproni, E | 1 |
| Ferrara, R | 1 |
| Bolasco, F | 1 |
| Cossu, M | 1 |
| Cadinu, F | 1 |
| Cabiddu, GF | 1 |
| Casu, D | 1 |
| Ganadu, M | 1 |
| Passaghe, M | 1 |
| Pinna, M | 1 |
| Mactier, RA | 1 |
| Sprosen, TS | 1 |
| Gokal, R | 1 |
| Williams, PF | 1 |
| Lindbergh, M | 1 |
| Naik, RB | 1 |
| Wrege, U | 1 |
| Gröntoft, KC | 1 |
| Larsson, R | 1 |
| Berglund, J | 1 |
| Tranaeus, AP | 1 |
| Fikry, T | 1 |
| al Harrar, R | 1 |
| Harfaoui, A | 1 |
| Harti, A | 1 |
| Zryouil, B | 1 |
| Campbell, IW | 1 |
| Duncan, LJ | 1 |
| Innes, JA | 1 |
| MacCuish, AC | 1 |
| Munro, JF | 1 |
| Cade, R | 1 |
| Spooner, G | 1 |
| Juncos, L | 1 |
| Fuller, T | 1 |
| Tarrant, D | 1 |
| Raulerson, D | 1 |
| Mahoney, J | 1 |
| Pickering, M | 1 |
| Grubb, W | 1 |
| Marbury, T | 1 |
| Dilawari, JB | 1 |
| Blendis, LM | 1 |
| Edwards, DA | 1 |
| Metzinger, SE | 1 |
| Bailey, DJ | 1 |
| Boyce, RG | 1 |
| Lyons, GD | 1 |
| Mitchell, D | 1 |
| Stubbs, A | 1 |
| Cheney, PR | 1 |
| Molzen, G | 1 |
| Tandberg, D | 1 |
| Stewart, JH | 1 |
| Chinn, SE | 1 |
| Cole, GW | 1 |
| Klein, JA | 1 |
| Armstrong, P | 1 |
| Watters, J | 1 |
| Whitfield, A | 1 |
| Martin, AJ | 1 |
| Eccarius, SG | 1 |
| Gordon, ME | 1 |
| Parelman, JJ | 1 |
| Sheard, C | 1 |
| Christoph, RA | 1 |
| Buchanan, L | 1 |
| Begalla, K | 1 |
| Schwartz, S | 1 |
| McKay, W | 1 |
| Morris, R | 1 |
| Mushlin, P | 1 |
| Adams, SL | 1 |
| Mathews, JJ | 1 |
| Flaherty, JJ | 1 |
| Knapp, MS | 1 |
| Gough, KR | 1 |
| Atkinson, M | 1 |
| Bennett, JR | 1 |
| Lewis, GB | 1 |
| Guy, RB | 1 |
| Rothenberg, SP | 1 |
| Cummings, JH | 1 |
| Sladen, GE | 1 |
| James, OF | 1 |
| Sarner, M | 1 |
| Misiewicz, JJ | 1 |
| Shirriffs, GG | 1 |
| Bewsher, PD | 1 |
| Barreras, L | 1 |
| Diggs, LW | 1 |
| Earlam, RJ | 1 |
| Ducassy, P | 1 |
| Lindahl, O | 2 |
| Knight, MJ | 1 |
| Condon, JR | 1 |
| Smith, R | 1 |
| Diekmeier, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures[NCT05294640] | Phase 4 | 95 participants (Actual) | Interventional | 2022-05-17 | Completed | ||
| The Efficacy of Analgesic Buffering With Sodium Bicarbonate for the Pediatric Dental Patient[NCT01883232] | 0 participants (Actual) | Interventional | 2013-08-31 | Withdrawn | |||
| Buffered vs Unbuffered Local Anesthesia Using Lidocaine, Carbocaine, and Articaine in Mandibular Molars Diagnosed With Symptomatic Irreversible Pulpitis[NCT06047366] | Phase 4 | 60 participants (Anticipated) | Interventional | 2023-12-05 | Recruiting | ||
| Buffered vs. Unbuffered Local Anesthesia in Mandibular Molars Diagnosed With Symptomatic Irreversible Pulpitis: A Controlled, Randomized Double-blind Study[NCT05227300] | Phase 4 | 40 participants (Anticipated) | Interventional | 2022-02-14 | Recruiting | ||
| Pain Perception Associated With Administration of Buffered Lidocaine Versus Conventional Lidocaine in the Pediatric Dental Patient[NCT04055116] | Phase 4 | 64 participants (Actual) | Interventional | 2019-11-11 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Time to gum numbness, assessed using periodontal probe and patient response. (NCT04055116)
Timeframe: Time of injection to 4 minutes post-injection (tested in 15 second intervals).
| Intervention | seconds (Mean) |
|---|---|
| Unbuffered Lidocaine | 102.21 |
| Buffered Lidocaine | 81.07 |
Wong-Baker FACES Pain Rating Scale responses after buffered and non-buffered lidocaine. Range: 0 - No Hurt to 10 - Hurts Worst (higher numbers indicate higher levels of pain). There are no sub-scores. (NCT04055116)
Timeframe: Within 1 minute of anesthetic administration
| Intervention | units on a scale (Mean) |
|---|---|
| Unbuffered Lidocaine | 3.52 |
| Buffered Lidocaine | 3.48 |
Faces, Legs, Arms, Crying Consolability (FLACC) Behavioral Pain Scale. This scale helps clinicians assess patients' pain based on behavioral observations. Range: 0 - 2 per category (higher number indicates more observed agitation/potential pain). A score is given in each of the five categories (Faces, Legs, Arms, Crying, Consolability). The sum of these scores provides the Assessment of Behavioral Score (range: 0 - 10) with higher scores indicating higher levels of pain. (NCT04055116)
Timeframe: During local anesthesia administration
| Intervention | units on a scale (Mean) |
|---|---|
| Unbuffered Lidocaine | 1.88 |
| Buffered Lidocaine | 2.43 |
7 reviews available for hydrogen carbonate and Pain
| Article | Year |
|---|---|
Pancreatic Dysfunction and Duodenal Inflammatory Responses Coordinate with Refractory Epigastric Pain Including Functional Dyspepsia: A Narrative Review.
Topics: Bicarbonates; Duodenum; Dyspepsia; Humans; Inflammation; Pain; Pancreatitis, Chronic | 2022 |
Patient Comfort with Various Local Infiltration Anesthetics for Minor Oculoplastic Surgery: A Systematic Review and Network Meta-Analysis.
Topics: Anesthesia, Local; Anesthetics, Local; Bicarbonates; Double-Blind Method; Epinephrine; Felypressin; | 2022 |
Reduced pain when injecting lidocaine.
Topics: Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Hot Temperature; Humans; Injections, S | 2017 |
Volume control in peritoneal dialysis patients: role of new dialysis solutions.
Topics: Acidosis; Bicarbonates; Blood Volume; Double-Blind Method; Glucans; Glucose; Glycation End Products, | 2004 |
Clinical trial experiences with Physioneal.
Topics: Acid-Base Equilibrium; Antibody Formation; Bicarbonates; Dentin-Bonding Agents; Dialysis Solutions; | 2003 |
Antacids and anticholinergics in the treatment of duodenal ulcer.
Topics: Aluminum Hydroxide; Antacids; Bicarbonates; Calcium Carbonate; Clinical Trials as Topic; Duodenal Ul | 1984 |
Sickle cell crisis.
Topics: Abdomen, Acute; Abortion, Therapeutic; Acidosis; Anemia, Sickle Cell; Bicarbonates; Citrates; Dehydr | 1973 |
23 trials available for hydrogen carbonate and Pain
| Article | Year |
|---|---|
Protocol for a double-blinded randomised controlled trial investigating the use of adjunct bicarbonate in carpal tunnel release: a single-centre study.
Topics: Anesthesia, Local; Anesthetics, Local; Bicarbonates; Carpal Tunnel Syndrome; Humans; Pain; Randomize | 2023 |
Efficacy of buffered local anaesthetics in head and neck infections.
Topics: Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Double-Blind Method; Female; Humans; H | 2019 |
Clinical experience with two physiologic bicarbonate/lactate peritoneal dialysis solutions in automated peritoneal dialysis.
Topics: Automation; Bicarbonates; Calcium; Dialysis Solutions; Gases; Humans; Lactic Acid; Pain; Patient Sat | 2003 |
Antacids and anticholinergics in the treatment of duodenal ulcer.
Topics: Aluminum Hydroxide; Antacids; Bicarbonates; Calcium Carbonate; Clinical Trials as Topic; Duodenal Ul | 1984 |
A comparative crossover study on the treatment of heartburn and epigastric pain: Liquid Gaviscon and a magnesium--aluminium antacid gel.
Topics: Abdomen; Adult; Aged; Alginates; Aluminum Hydroxide; Antacids; Bicarbonates; Drug Combinations; Fema | 1980 |
Clinical advantages of acetate-free biofiltration.
Topics: Acetates; Acidosis; Adult; beta 2-Microglobulin; Bicarbonates; Blood Urea Nitrogen; Cardiovascular D | 1994 |
New treatment for rectal impaction in children: an efficacy, comfort, and safety trial of the pulsed-irrigation enhanced-evacuation procedure.
Topics: Adolescent; Bicarbonates; Child; Child, Preschool; Chlorides; Chronic Disease; Constipation; Enema; | 1994 |
Intralesional vinblastine for cutaneous Kaposi's sarcoma associated with acquired immunodeficiency syndrome. A clinical trial to evaluate efficacy and discomfort associated with infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; Bicarbonates; Buffers; Humans; Injections, Intralesional; | 1993 |
Buffered versus plain lidocaine for digital nerve blocks.
Topics: Adolescent; Adult; Bicarbonates; Buffers; Double-Blind Method; Female; Fingers; Humans; Injections; | 1993 |
pH adjustment of mepivacaine decreases the incidence of tourniquet pain during axillary brachial plexus anaesthesia.
Topics: Adult; Anesthesia, General; Arm; Axilla; Bicarbonates; Brachial Plexus; Female; Hand; Humans; Hydrog | 1993 |
Less painful alternatives for local anesthesia.
Topics: Adult; Aged; Anesthesia, Local; Bicarbonates; Buffers; Double-Blind Method; Epinephrine; Humans; Inj | 1993 |
Sodium bicarbonate alleviates penile pain induced by intracavernous injections for erectile dysfunction.
Topics: Adult; Aged; Alprostadil; Bicarbonates; Double-Blind Method; Drug Combinations; Erectile Dysfunction | 1993 |
Regional anaesthetic technique and the incidence of tourniquet pain.
Topics: Anesthesia, Epidural; Anesthesia, Spinal; Bicarbonates; Bupivacaine; Humans; Hydrogen-Ion Concentrat | 1993 |
An erbium:YAG laser to obtain capillary blood samples without a needle for point-of-care laboratory testing.
Topics: Bicarbonates; Blood Glucose; Blood Specimen Collection; Blood Urea Nitrogen; Capillaries; Diabetes M | 1997 |
On-line predilution hemofiltration versus ultrapure high-flux hemodialysis: a multicenter prospective study in 23 patients. Sardinian Collaborative Study Group of On-Line Hemofiltration.
Topics: Aged; Arrhythmias, Cardiac; beta 2-Microglobulin; Bicarbonates; Body Weight; Electrolytes; Fatigue; | 1997 |
Bicarbonate and bicarbonate/lactate peritoneal dialysis solutions for the treatment of infusion pain.
Topics: Bicarbonates; Cross-Over Studies; Dialysis Solutions; Double-Blind Method; Humans; Lactates; Middle | 1998 |
[Local digital anesthesia using lidocaine with or without bicarbonate. A comparative randomized study].
Topics: Adult; Alkalies; Ambulatory Surgical Procedures; Anesthesia, Local; Anesthetics, Local; Bicarbonates | 1998 |
The effect of pH buffering on reducing the pain associated with subcutaneous infiltration of bupivicaine.
Topics: Adult; Bicarbonates; Buffers; Bupivacaine; Double-Blind Method; Drug Combinations; Drug Stability; H | 1991 |
Alkalinisation of prilocaine for intravenous regional anaesthesia. Suitability for clinical use.
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, Conduction; Anesthesia, Intrave | 1990 |
pH-adjustment and discomfort caused by the intradermal injection of lignocaine.
Topics: Adult; Anesthesia, Local; Bicarbonates; Epinephrine; Female; Humans; Hydrogen-Ion Concentration; Inj | 1990 |
Bicarbonate-buffered lidocaine-epinephrine-hyaluronidase for eyelid anesthesia.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bicarbonates; Buffers; Cataract Extraction; Doub | 1990 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Pain reduction in local anesthetic administration through pH buffering.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Clinical Trials as Topic; Doubl | 1988 |
Clinical trials of therapy for sickle cell vaso-occlusive crises. Cooperative urea trials group.
Topics: Alkalies; Anemia, Sickle Cell; Arterial Occlusive Diseases; Bicarbonates; Blood Urea Nitrogen; Evalu | 1974 |
34 other studies available for hydrogen carbonate and Pain
| Article | Year |
|---|---|
The use of porcine xenografts in patients with toxic epidermal necrolysis.
Topics: Adult; Aged; Animals; Bandages; Bicarbonates; Biological Dressings; Blood Glucose; Blood Urea Nitrog | 2016 |
Listen to the patient.
Topics: Acetaminophen; Bicarbonates; Deglutition Disorders; Drug Combinations; Female; Fractures, Bone; Huma | 2008 |
TREATMENT OF PAINFUL CRISES OF SICKLE CELL DISEASE. A DOUBLE BLIND STUDY.
Topics: Anemia; Anemia, Sickle Cell; Bicarbonates; Child; Double-Blind Method; Erythrocytes, Abnormal; Human | 1964 |
[CLINICAL EXPERIMENTATION WITH TH-2152 IN PAINFUL TENSION OF THE BREASTS DURING ESTABLISHMENT OF MILK FLOW].
Topics: Aspirin; Bicarbonates; Biomedical Research; Breast Feeding; Female; Gastric Mucosa; Humans; Infant, | 1964 |
[USE OF TH-2152 IN PAINFUL SYNDROMES].
Topics: Abscess; Analgesia; Aspirin; Back Pain; Bicarbonates; Biomedical Research; Burns; Craniocerebral Tra | 1964 |
[TH-2152 APROPOS OF SOME CLINICAL EXPERIMENTATION IN THE INFECTIOUS DISEASES AND RESUSCITATION DEPARTMENT OF THE CENTRE HOSPITALIER UNIVERSITAIRE D'ANGERS].
Topics: Analgesia; Anger; Aspirin; Bicarbonates; Biomedical Research; Communicable Diseases; Pain; Resuscita | 1964 |
[CLINICAL EXPERIMENTATION WITH TH-2152 IN GYNECOLOGY AND OBSTETRICS].
Topics: Analgesia; Aspirin; Bicarbonates; Biomedical Research; Dysmenorrhea; Female; Gynecology; Headache; H | 1964 |
[PHARMACOLOGICAL STUDY OF TH-2152].
Topics: Analgesia; Aspirin; Bicarbonates; Bradykinin; Dogs; Fever; Gastric Mucosa; Inflammation; Pain; Pharm | 1964 |
EXPERIENCES WITH PERITONEAL DIALYSIS.
Topics: Bicarbonates; Dialysis; Drainage; Equipment and Supplies; Fluid Therapy; Hemoperitoneum; Humans; Kid | 1965 |
Comparison of buffered and unbuffered local anaesthesia for inguinal hernia repair: a prospective study.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Hernia | 2006 |
Pain provocation test in peptic duodenitis.
Topics: Bicarbonates; Duodenitis; Endoscopy; Humans; Hydrochloric Acid; Methods; Pain; Sodium Bicarbonate; S | 1983 |
The anion gap as a prognostic indicator in horses with abdominal pain.
Topics: Abdomen; Acid-Base Equilibrium; Acidosis; Animals; Bicarbonates; Chlorides; Horse Diseases; Horses; | 1982 |
Acetate-free biofiltration: acidosis correction and cardiovascular stability.
Topics: Acetates; Acidosis; Bicarbonates; Cardiovascular Diseases; Evaluation Studies as Topic; Gastrointest | 1994 |
Abdominal pain in diabetic metabolic decompensation. Clinical significance.
Topics: Abdomen; Adult; Age Factors; Bicarbonates; Blood Glucose; Dehydration; Diabetes Complications; Diabe | 1975 |
Chronic renal vein thrombosis.
Topics: Adolescent; Adult; Aged; Angiography; Bicarbonates; Biopsy; Chlorides; Chronic Disease; Female; Fibr | 1977 |
Epigastric pain in duodenal ulcer.
Topics: Bicarbonates; Duodenal Ulcer; Esophagogastric Junction; Gastroesophageal Reflux; Humans; Hydrochlori | 1975 |
Local anesthesia in rhinoplasty: a new twist?
Topics: Adult; Anesthesia, Local; Bicarbonates; Bupivacaine; Female; Humans; Injections; Lidocaine; Male; Mi | 1992 |
pH-adjusted local anaesthetics.
Topics: Anesthesia, Local; Bicarbonates; Humans; Hydrogen-Ion Concentration; Lidocaine; Pain; Sodium; Sodium | 1992 |
Neutralized lidocaine with epinephrine for local anesthesia--II.
Topics: Anesthesia, Local; Bicarbonates; Dermatologic Surgical Procedures; Double-Blind Method; Epinephrine; | 1990 |
Mistaken injection of sodium bicarbonate.
Topics: Anesthesia, Local; Bicarbonates; Humans; Injections, Subcutaneous; Lidocaine; Nose; Pain; Sodium; So | 1989 |
Sodium bicarbonate attenuates pain on skin infiltration with lidocaine, with or without epinephrine.
Topics: Bicarbonates; Double-Blind Method; Drug Evaluation; Epinephrine; Humans; Hydrogen-Ion Concentration; | 1987 |
Alcoholic ketoacidosis.
Topics: Acidosis; Alcoholism; Bicarbonates; Emergency Medical Services; Fluid Therapy; Hospitalization; Huma | 1987 |
An unusual neurological manifestation of hypocalcaemia.
Topics: Adolescent; Adult; Anemia, Macrocytic; Bicarbonates; Calcium; Ergocalciferols; Female; Folic Acid De | 1967 |
Relationship between motor changes and pain during esophageal acid perfusion.
Topics: Bicarbonates; Esophagoscopy; Esophagus; Gastroesophageal Reflux; Hernia, Diaphragmatic; Humans; Hydr | 1968 |
Prolonged regional analgesia in scleroderma.
Topics: Amputation, Surgical; Analgesia; Bicarbonates; Dextrans; Female; Fingers; Humans; Hydrogen-Ion Conce | 1974 |
Laxative-induced diarrhoea: a continuing clinical problem.
Topics: Abdomen; Adult; Aged; Bicarbonates; Body Weight; Cathartics; Colon; Diarrhea; Feces; Female; Humans; | 1974 |
Hypothermia, abdominal pain, and lactic acidosis in phenformin-treated diabetic.
Topics: Abdomen; Aged; Bicarbonates; Blood Chemical Analysis; Blood Pressure; Body Temperature; Diabetes Mel | 1970 |
Sodium citrate orally for painful sickle cell crises.
Topics: Acetazolamide; Adult; Ammonium Chloride; Anemia, Sickle Cell; Bicarbonates; Citrates; Codeine; Fever | 1971 |
Further experience with epigastric pain reproduction test in duodenal ulceration.
Topics: Bicarbonates; Duodenal Ulcer; Esophagogastric Junction; Esophagus; Humans; Hydrochloric Acid; Pain; | 1972 |
[The treatment of certain forms of cholecystosis with sodium bicarbonated waters at the Boulou balneologic station].
Topics: Balneology; Bicarbonates; Cholecystectomy; Cholecystitis; Deglutition Disorders; Endometriosis; Fema | 1972 |
Metabolic treatment in diffuse pain (varialgia).
Topics: Acid-Base Equilibrium; Bicarbonates; Calcium; Citrates; Humans; Hydrogen-Ion Concentration; Lactates | 1966 |
Changes in the acid-base balance in metabolic treatment for pain.
Topics: Acid-Base Equilibrium; Ammonium Chloride; Bicarbonates; Chronic Disease; Humans; Hydrogen-Ion Concen | 1970 |
Possible use of glucagon in the treatment of pancreatitis.
Topics: Abdomen; Acute Disease; Adult; Aged; Amylases; Bicarbonates; Blood Glucose; Calcium; Chronic Disease | 1971 |
[The neural therapy aspects of periosteum therapy].
Topics: Bicarbonates; Pain; Periosteum; Procaine | 1964 |