Page last updated: 2024-10-18

hydrogen carbonate and Osteosarcoma

hydrogen carbonate has been researched along with Osteosarcoma in 6 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Osteosarcoma is one of the most common types of primary bone cancers."1.56Cytotoxic and osteogenic effects of crocin and bicarbonate from calcium phosphates for potential chemopreventative and anti-inflammatory applications in vitro and in vivo. ( Bose, S; Koski, C; Sarkar, N, 2020)
" No significant relationship was observed between alpha value and total amount of transfusion, of urine or dosage of sodium bicarbonate."1.27[Effect of IV hydration with sodium bicarbonate on high-dose methotrexate disposition kinetics]. ( Goto, M; Konishi, H; Tsuda, N; Yamashina, H, 1984)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Koski, C1
Sarkar, N1
Bose, S1
Tsuda, N1
Goto, M1
Konishi, H1
Yamashina, H1
Ferrari, S1
Zolezzi, C1
Cesari, M1
Fasano, MC1
Lamanna, G1
Bacci, G1
Romolo, JL1
Goldberg, NH1
Hande, KR1
Rosenberg, SA1
Star, RA1
Zhang, BX1
Loessberg, PA1
Muallem, S2
Green, J1
Yamaguchi, DT1
Kleeman, CR1

Trials

1 trial available for hydrogen carbonate and Osteosarcoma

ArticleYear
Prospective evaluation of high-dose ifosfamide-related nephrotoxicity in young adult patients with recurrent osteosarcoma previously treated with cisplatin, methotrexate and standard-dose ifosfamide.
    Anti-cancer drugs, 1999, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols

1999

Other Studies

5 other studies available for hydrogen carbonate and Osteosarcoma

ArticleYear
Cytotoxic and osteogenic effects of crocin and bicarbonate from calcium phosphates for potential chemopreventative and anti-inflammatory applications in vitro and in vivo.
    Journal of materials chemistry. B, 2020, 03-11, Volume: 8, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bicarbonates; Calcium Phosphates; Carotenoids; Cel

2020
[Effect of IV hydration with sodium bicarbonate on high-dose methotrexate disposition kinetics].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Bicarbonates; Bone Neoplasms; Child; Female; Humans; Hydrogen-Ion Concentration;

1984
Effect of hydration on plasma-methotrexate levels.
    Cancer treatment reports, 1977, Volume: 61, Issue:7

    Topics: Adolescent; Adult; Bicarbonates; Bone Neoplasms; Child; Female; Humans; Infusions, Parenteral; Leuco

1977
Regulatory volume decrease in the presence of HCO3- by single osteosarcoma cells UMR-106-01.
    The Journal of biological chemistry, 1992, Sep-05, Volume: 267, Issue:25

    Topics: Animals; Bicarbonates; Carrier Proteins; Cell Line; Hydrogen-Ion Concentration; Kinetics; Osteosarco

1992
Cytosolic pH regulation in osteoblasts. Regulation of anion exchange by intracellular pH and Ca2+ ions.
    The Journal of general physiology, 1990, Volume: 95, Issue:1

    Topics: Animals; Bicarbonates; Calcium; Cell Line; Chlorides; Clone Cells; Cytosol; Hydrogen-Ion Concentrati

1990