Page last updated: 2024-10-18

hydrogen carbonate and Obesity Hypoventilation Syndrome

hydrogen carbonate has been researched along with Obesity Hypoventilation Syndrome in 12 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Obesity Hypoventilation Syndrome: HYPOVENTILATION syndrome in very obese persons with excessive ADIPOSE TISSUE around the ABDOMEN and DIAPHRAGM. It is characterized by diminished to absent ventilatory chemoresponsiveness; chronic HYPOXIA; HYPERCAPNIA; POLYCYTHEMIA; and long periods of sleep during day and night (HYPERSOMNOLENCE). It is a condition often related to OBSTRUCTIVE SLEEP APNEA but can occur separately.

Research Excerpts

ExcerptRelevanceReference
"Among patients with MA and COPD or OHS, early treatment with ACTZ did not shorten significantly the duration of MV compared with placebo."2.84Effects of early administration of acetazolamide on the duration of mechanical ventilation in patients with chronic obstructive pulmonary disease or obesity-hypoventilation syndrome with metabolic alkalosis. A randomized trial. ( Heras la Calle, G; Martín Delgado, MC; Mas Serra, A; Morán Chorro, I; Raurich Puigdevall, JM; Rialp Cervera, G; Vallverdú Perapoch, I, 2017)
"Therefore, the diagnosis of obesity hypoventilation syndrome (OHS) is underestimated."1.42Clinical predictors of obesity hypoventilation syndrome in obese subjects with obstructive sleep apnea. ( Bingol, Z; Cagatay, P; Kıyan, E; Okumus, G; Pıhtılı, A, 2015)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's11 (91.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Raphelson, JR1
Schmickl, CN1
Sonners, C1
Kreitinger, K1
Grunvald, E1
Horgan, S1
Malhotra, A1
Hollier, CA1
Maxwell, LJ1
Harmer, AR1
Menadue, C1
Piper, AJ1
Black, DA1
Willson, GN1
Alison, JA1
Manuel, ARG1
Hart, N1
Stradling, JR1
Bingol, Z1
Pıhtılı, A1
Cagatay, P1
Okumus, G1
Kıyan, E1
Palen, BN1
Swenson, ER1
Monneret, D2
Devilliers, C1
Bonnefont-Rousselot, D1
Raveendran, R1
Wong, J1
Singh, M1
Wong, DT1
Chung, F1
Rialp Cervera, G1
Raurich Puigdevall, JM1
Morán Chorro, I1
Martín Delgado, MC1
Heras la Calle, G1
Mas Serra, A1
Vallverdú Perapoch, I1
Raurich, JM1
Rialp, G1
Ibáñez, J1
Llompart-Pou, JA1
Ayestarán, I1
Powers, MA1
Prieto de Paula, JM1
Franco Hidalgo, S1
Borge Gallardo, L1
Mayor Toranzo, E1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Factors Associated With Chronic Respiratory Failure in Obesity: A Cross-sectional Study[NCT01380418]78 participants (Actual)Observational2011-06-30Completed
Effects of Acetazolamide on the Duration of Mechanical Ventilation in Patients With Metabolic Alkalosis. Phase III Multicenter Double-blinded Clinical Trial.[NCT01499485]Phase 3140 participants (Actual)Interventional2011-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydrogen carbonate and Obesity Hypoventilation Syndrome

ArticleYear
Obesity hypoventilation syndrome, sleep apnea, overlap syndrome: perioperative management to prevent complications.
    Current opinion in anaesthesiology, 2017, Volume: 30, Issue:1

    Topics: Anesthesia; Bicarbonates; Elective Surgical Procedures; Humans; Obesity Hypoventilation Syndrome; Pe

2017

Trials

1 trial available for hydrogen carbonate and Obesity Hypoventilation Syndrome

ArticleYear
Effects of early administration of acetazolamide on the duration of mechanical ventilation in patients with chronic obstructive pulmonary disease or obesity-hypoventilation syndrome with metabolic alkalosis. A randomized trial.
    Pulmonary pharmacology & therapeutics, 2017, Volume: 44

    Topics: Acetazolamide; Acidosis; Aged; Bicarbonates; Blood Gas Analysis; Double-Blind Method; Female; Follow

2017

Other Studies

10 other studies available for hydrogen carbonate and Obesity Hypoventilation Syndrome

ArticleYear
Obesity Hypoventilation Syndrome and Postsurgical Outcomes in a Bariatric Surgery Cohort.
    Obesity surgery, 2022, Volume: 32, Issue:7

    Topics: Bariatric Surgery; Bicarbonates; Humans; Obesity Hypoventilation Syndrome; Obesity, Morbid; Weight L

2022
Validity of arterialised-venous P CO2, pH and bicarbonate in obesity hypoventilation syndrome.
    Respiratory physiology & neurobiology, 2013, Aug-15, Volume: 188, Issue:2

    Topics: Adult; Arteries; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Female; Humans; Hydrogen-Ion Conc

2013
Is a raised bicarbonate, without hypercapnia, part of the physiologic spectrum of obesity-related hypoventilation?
    Chest, 2015, Volume: 147, Issue:2

    Topics: Adult; Bicarbonates; Blood Gas Analysis; Cross-Sectional Studies; Female; Humans; Male; Middle Aged;

2015
Clinical predictors of obesity hypoventilation syndrome in obese subjects with obstructive sleep apnea.
    Respiratory care, 2015, Volume: 60, Issue:5

    Topics: Aged; Bicarbonates; Blood Gas Analysis; Body Mass Index; Female; Humans; Male; Middle Aged; Obesity;

2015
Is a raised eucapnic blood bicarbonate value a Bellwether of preclinical obesity hypoventilation syndrome?
    Chest, 2015, Volume: 147, Issue:2

    Topics: Bicarbonates; Female; Humans; Male; Obesity Hypoventilation Syndrome

2015
Comparison of measured venous carbon dioxide and calculated arterial bicarbonates according to the PaCO2 and PaO2 cut-off values of obesity hypoventilation syndrome.
    Clinical chemistry and laboratory medicine, 2015, Volume: 53, Issue:12

    Topics: Arterial Pressure; Arteries; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Humans; Obesity Hypov

2015
Bicarbonate or base excess in early obesity hypoventilation syndrome: a methodologic viewpoint.
    Chest, 2015, Volume: 147, Issue:6

    Topics: Bicarbonates; Female; Humans; Male; Obesity Hypoventilation Syndrome

2015
Hypercapnic respiratory failure in obesity-hypoventilation syndrome: CO₂ response and acetazolamide treatment effects.
    Respiratory care, 2010, Volume: 55, Issue:11

    Topics: Acetazolamide; Aged; Alkalosis; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Carbonic Anhydrase

2010
Obesity hypoventilation syndrome: bicarbonate concentration and acetazolamide.
    Respiratory care, 2010, Volume: 55, Issue:11

    Topics: Acetazolamide; Alkalosis; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Carbonic Anhydrase Inhib

2010
The importance of identifying the association between metabolic alkalosis and respiratory acidosis.
    Archivos de bronconeumologia, 2012, Volume: 48, Issue:2

    Topics: Acetazolamide; Acidosis, Respiratory; Alkalosis; Bicarbonates; Furosemide; Humans; Obesity Hypoventi

2012