Page last updated: 2024-10-18

hydrogen carbonate and Necrosis

hydrogen carbonate has been researched along with Necrosis in 47 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Methanol toxicity can cause severe central nervous system insult in which a characteristic pattern of bilateral putaminal injury is noted on brain imaging studies."1.30Putaminal infarct in methanol intoxication: case report and role of brain imaging studies. ( Frank, LR; Krenzelok, EP; Roberge, RJ; Scorza, L; Srinivasa, NS, 1998)
" Larger doses of ID HC did not prevent local doxorubicin toxicity and were inherently toxic to the skin."1.26The limited role of corticosteroids in ameliorating experimental doxorubicin skin toxicity in the mouse. ( Alberts, DS; Chen, HS; Dorr, RT, 1980)
"This mucosal injury was enhanced by hemorrhagic shock in the control dogs."1.26Protection of gastric mucosa against acute ulceration by intravenous infusion of sodium bicarbonate. ( Cheung, LY; Porterfield, G, 1979)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199033 (70.21)18.7374
1990's6 (12.77)18.2507
2000's2 (4.26)29.6817
2010's5 (10.64)24.3611
2020's1 (2.13)2.80

Authors

AuthorsStudies
Calame, P1
Winiszewski, H1
Doussot, A1
Malakhia, A1
Grillet, F1
Verdot, P1
Vuitton, L1
Ronot, M1
Pili-Floury, S1
Heyd, B1
Delabrousse, E1
Piton, G1
Mehta, RL1
Awdishu, L1
Davenport, A1
Murray, PT1
Macedo, E1
Cerda, J1
Chakaravarthi, R1
Holden, AL1
Goldstein, SL1
Westerkamp, AC1
Karimian, N1
Matton, AP1
Mahboub, P1
van Rijn, R1
Wiersema-Buist, J1
de Boer, MT1
Leuvenink, HG1
Gouw, AS1
Lisman, T1
Porte, RJ1
Najafi, H1
Owji, SM1
Kamali-Sarvestani, E1
Moosavi, SM1
Pajek, J1
Kveder, R1
Gucek, A1
Skoberne, A1
Bren, A1
Bucar, M1
Cerne, D1
Lukac-Bajalo, J1
Carreras-González, E1
Brió-Sanagustín, S1
Guimerá, I1
Crespo, C1
ERLANSON, P1
FRITZ, H1
HAGSTAM, KE1
LILJENBERG, B1
TRYDING, N1
VOIGT, G1
Maccariello, E1
Dalboni, MA1
Draibe, SA1
Rocha, E1
Pavão dos Santos, OF1
Santos, B1
Cendoroglo, M1
Book, LS1
Herbst, JJ1
Bartkowski-Dodds, L1
Daniels, JR1
Barr, RD1
Sertic, J1
Satterwhite, B1
Ewy, GA1
Reichstein, BJ1
Cohen, MM1
Poole-Wilson, PA1
Dorr, RT1
Alberts, DS1
Chen, HS1
Roberge, RJ1
Srinivasa, NS1
Frank, LR1
Scorza, L1
Krenzelok, EP1
Plum, J2
Lordnejad, MR1
Grabensee, B2
Razeghi, P1
Lordnejad, RM1
Perniok, A1
Fleisch, M1
Fusshöller, A1
Schneider, M1
Orvell, BD1
Wesson, LG1
Cheung, LY1
Porterfield, G1
Gaze, NR1
Larsen, OS1
Riegels-Nielsen, P1
Ejerblad, S2
Eriksson, I1
Johansson, H1
Jackson, IT1
Robinson, DW1
Tiller, R1
Frey, G1
Bemmel, LA1
Hack, WW1
Seldenrijk, CA1
Kneepkens, CM1
Riegler, M1
Feil, W1
Wenzl, E1
Schiessel, R1
Olney, JW1
Zorumski, C1
Price, MT1
Labruyere, J1
Starlinger, M1
Cesolari, JA1
Laudanno, OM1
San Miguel, P1
Bedini, OA1
Banner, W1
Tong, TG1
Austin, G1
Mesa, M1
Lambert, C1
Labram, C1
Gervais, P1
Battersby, C1
Egerton, W1
Balderson, G1
Kerr, JF1
Burnett, W1
Ballard, RA1
Kraybill, EN1
Hernandez, J1
Renfield, ML1
Blankenship, WJ1
Grivaux, M1
Soulié, J1
Diallo, A1
Renard, C1
Chevalley, J1
Downs, JB1
Chapman, RL1
Modell, JH1
Hood, CI1
MacGregor, DC1
Wilson, GJ1
Holness, DE1
Lixfeld, W1
Yasui, H1
Tanaka, S1
Silver, MD1
Gunstensen, J1
Perret, C2
Spennati, GF1
Ceccamea, A1
Annibaldi, L1
Cuschieri, A1
Baker, PR1
Shields, R1
Solymoss, B1
Classen, HG1
Varga, S1
Falchuk, KH1
Goetzl, EJ1
Kulka, JP1
Enrico, JF1
Montani, S1
Pappalardo, G1
Goldenberg, VE1
Wiegenstein, L1
Hopkins, GB1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Genetic Contribution to Drug Induced Renal Injury: The Drug Induced Renal Injury Consortium (DIRECT)[NCT02159209]634 participants (Actual)Observational2013-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for hydrogen carbonate and Necrosis

ArticleYear
Recent advances in cardiopulmonary resuscitation and defibrillation.
    Current problems in cardiology, 1983, Volume: 8, Issue:1

    Topics: Animals; Bicarbonates; Calcium Chloride; Cardiac Pacing, Artificial; Cardiography, Impedance; Electr

1983
Acidosis and contractility of heart muscle.
    Ciba Foundation symposium, 1982, Volume: 87

    Topics: Acidosis; Acidosis, Respiratory; Animals; Bicarbonates; Calcium; Carbon Dioxide; Coronary Disease; D

1982
Iron poisoning.
    Pediatric clinics of North America, 1986, Volume: 33, Issue:2

    Topics: Absorption; Bicarbonates; Chemical and Drug Induced Liver Injury; Child, Preschool; Deferoxamine; Di

1986

Trials

1 trial available for hydrogen carbonate and Necrosis

ArticleYear
Cell-free DNA in the peritoneal effluent of peritoneal dialysis solutions.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2010, Volume: 14, Issue:1

    Topics: Apoptosis; Ascitic Fluid; Bicarbonates; Biomarkers; Buffers; Cell-Free System; Cross-Over Studies; D

2010

Other Studies

43 other studies available for hydrogen carbonate and Necrosis

ArticleYear
Evaluating the Risk of Irreversible Intestinal Necrosis Among Critically Ill Patients With Nonocclusive Mesenteric Ischemia.
    The American journal of gastroenterology, 2021, 07-01, Volume: 116, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Bicarbonates; Critical Illness; Female; Humans; Intestine, Small; La

2021
Phenotype standardization for drug-induced kidney disease.
    Kidney international, 2015, Volume: 88, Issue:2

    Topics: Acute Kidney Injury; Bicarbonates; Biopsy; Consensus; Creatinine; Delphi Technique; Electrolytes; Gl

2015
Oxygenated Hypothermic Machine Perfusion After Static Cold Storage Improves Hepatobiliary Function of Extended Criteria Donor Livers.
    Transplantation, 2016, Volume: 100, Issue:4

    Topics: Adenosine Triphosphate; Aged; Bicarbonates; Bile; Bilirubin; Biomarkers; Cold Ischemia; Donor Select

2016
A1 -Adenosine receptor activation has biphasic roles in development of acute kidney injury at 4 and 24 h of reperfusion following ischaemia in rats.
    Experimental physiology, 2016, 07-01, Volume: 101, Issue:7

    Topics: Acute Kidney Injury; Animals; Apoptosis; Bicarbonates; Cell Movement; Cytokines; Hemodynamics; Infla

2016
[Complication of the intraosseous route in a newborn infant].
    Medicina intensiva, 2012, Volume: 36, Issue:3

    Topics: Advanced Cardiac Life Support; Bicarbonates; Crystalloid Solutions; Edema; Epinephrine; Erythema; Fe

2012
SEVERE METHANOL INTOXICATION.
    Acta medica Scandinavica, 1965, Volume: 177

    Topics: Acidosis; Bicarbonates; Brain Diseases; Drug Therapy; Ethanol; Geriatrics; Humans; Kidneys, Artifici

1965
Effects of customized bicarbonate buffered solutions for continuous renal replacement therapies on polymorphonuclear leukocytes function and viability.
    Artificial organs, 2004, Volume: 28, Issue:6

    Topics: Analysis of Variance; Apoptosis; Bicarbonates; Buffers; Cell Survival; Evaluation Studies as Topic;

2004
Intra-arterial infusions and intestinal necrosis in the rabbit: potential hazards of umbilical artery injections of ampicillin, glucose, and sodium bicarbonate.
    Pediatrics, 1980, Volume: 65, Issue:6

    Topics: Ampicillin; Animals; Bicarbonates; Glucose; Humans; Ileum; Infant, Newborn; Injections, Intra-Arteri

1980
Use of sodium bicarbonate as a means of ameliorating doxorubicin-induced dermal necrosis in rats.
    Cancer chemotherapy and pharmacology, 1980, Volume: 4, Issue:3

    Topics: Animals; Bicarbonates; Doxorubicin; Injections, Intradermal; Necrosis; Rats; Skin Diseases; Sodium B

1980
Soft-tissue necrosis induced by extravasated cancer chemotherapeutic agents: a study of active intervention.
    British journal of cancer, 1981, Volume: 44, Issue:2

    Topics: Animals; Bicarbonates; Doxorubicin; Guinea Pigs; Hydrocortisone; Indomethacin; Necrosis; Skin; Sodiu

1981
Extravasation management.
    Oncology nursing forum, 1982,Summer, Volume: 9, Issue:3

    Topics: Bicarbonates; Doxorubicin; Humans; Necrosis; Sodium Bicarbonate

1982
Effect of acetazolamide on rat gastric mucosal protection and stimulated bicarbonate secretion with 16,16-dimethyl PGE2.
    The Journal of laboratory and clinical medicine, 1984, Volume: 104, Issue:5

    Topics: 16,16-Dimethylprostaglandin E2; Acetazolamide; Animals; Bicarbonates; Ethanol; Gastric Mucosa; Hydro

1984
The limited role of corticosteroids in ameliorating experimental doxorubicin skin toxicity in the mouse.
    Cancer chemotherapy and pharmacology, 1980, Volume: 5, Issue:1

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Antidotes; Bicarbonates; Dexamethasone;

1980
Putaminal infarct in methanol intoxication: case report and role of brain imaging studies.
    Veterinary and human toxicology, 1998, Volume: 40, Issue:2

    Topics: Adult; Basal Ganglia; Bicarbonates; Brain Edema; Cerebral Infarction; Fatal Outcome; Female; Humans;

1998
Effect of alternative peritoneal dialysis solutions on cell viability, apoptosis/necrosis and cytokine expression in human monocytes.
    Kidney international, 1998, Volume: 54, Issue:1

    Topics: Actins; Apoptosis; Bicarbonates; Buffers; Cell Survival; Dialysis Solutions; Flow Cytometry; Gene Ex

1998
Peritoneal dialysis fluids with a physiologic pH based on either lactate or bicarbonate buffer-effects on human mesothelial cells.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 38, Issue:4

    Topics: Adenosine Triphosphate; Apoptosis; Bicarbonates; Buffers; Dialysis Solutions; Epithelial Cells; Flow

2001
Some effects of ammonium salts on renal histology and function in the dog.
    Nephron, 1976, Volume: 16, Issue:1

    Topics: Ammonia; Ammonium Chloride; Animals; Bicarbonates; Creatinine; Dogs; Electrolytes; Female; Hydrogen-

1976
Protection of gastric mucosa against acute ulceration by intravenous infusion of sodium bicarbonate.
    American journal of surgery, 1979, Volume: 137, Issue:1

    Topics: Animals; Bicarbonates; Blood; Dogs; Gastric Mucosa; Hydrogen-Ion Concentration; Infusions, Parentera

1979
Tissue necrosis caused by commonly used intravenous infusions.
    Lancet (London, England), 1978, Aug-19, Volume: 2, Issue:8086

    Topics: Antineoplastic Agents; Bicarbonates; Epinephrine; Female; Humans; Infusions, Parenteral; Male; Middl

1978
[Hand lesions after infusion of hypertonic sodium bicarbonate].
    Ugeskrift for laeger, 1979, Jun-18, Volume: 141, Issue:25

    Topics: Bicarbonates; Cyanosis; Edema; Hand; Humans; Hypertonic Solutions; Infusions, Parenteral; Male; Midd

1979
Uraemic arterial disease. An experimental study with special reference to the effect of parathyroidectomy.
    Scandinavian journal of urology and nephrology, 1979, Volume: 13, Issue:2

    Topics: Adrenal Glands; Animals; Arteries; Bicarbonates; Blood Pressure; Calcinosis; Calcium; Cholesterol; C

1979
Uraemic myocardial disease. An experimental study, with special reference to the effect of parathyroidectomy.
    Acta chirurgica Scandinavica, 1979, Volume: 145, Issue:5

    Topics: Adrenal Glands; Animals; Arteries; Bicarbonates; Blood Pressure; Calcinosis; Calcium; Cholesterol; C

1979
Severe tissue damage following accidental subcutaneous infusion of bicarbonate solution.
    Scottish medical journal, 1976, Volume: 21, Issue:4

    Topics: Bicarbonates; Hand; Humans; Injections, Subcutaneous; Male; Middle Aged; Necrosis; Resuscitation; Sk

1976
[Temporal and ear necroses as sequelae of erroneous infusions of hyperosmolar solutions in the right temporal artery of a premature infant].
    Zeitschrift fur arztliche Fortbildung, 1977, Aug-01, Volume: 71, Issue:15

    Topics: Bicarbonates; Ear; Ear Diseases; Facial Paralysis; Humans; Infant, Newborn; Infant, Premature; Infan

1977
Extensive hepatic necrosis in a premature infant.
    Journal of pediatric gastroenterology and nutrition, 1992, Volume: 14, Issue:2

    Topics: Acyclovir; Alanine Transaminase; Aspartate Aminotransferases; Bicarbonates; Cloxacillin; Dopamine; F

1992
Factors influencing the restitution of the duodenal and colonic mucosa after damage.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1991, Volume: 42, Issue:1

    Topics: Animals; Bicarbonates; Calcium; Colon; Deoxycholic Acid; Duodenum; Epithelial Cells; Epithelium; Hum

1991
L-cysteine, a bicarbonate-sensitive endogenous excitotoxin.
    Science (New York, N.Y.), 1990, May-04, Volume: 248, Issue:4955

    Topics: Animals; Animals, Newborn; Anticonvulsants; Aspartic Acid; Bicarbonates; Caudate Nucleus; Chick Embr

1990
Role of alkaline secretion and cell restitution in duodenal mucosal protection.
    Journal of internal medicine. Supplement, 1990, Volume: 732

    Topics: Acid-Base Equilibrium; Animals; Bicarbonates; Duodenum; Gastric Acid; In Vitro Techniques; Intestina

1990
[Drugs cytoprotective of the gastric mucosa against ethanol damage].
    Revista espanola de las enfermedades del aparato digestivo, 1988, Volume: 73, Issue:3

    Topics: Acetaminophen; Aluminum Hydroxide; Animals; Bicarbonates; Drug Evaluation, Preclinical; Enprostil; E

1988
The Keyes technique and self-inflicted injuries. Three case reports.
    Journal of periodontology, 1985, Volume: 56, Issue:9

    Topics: Bicarbonates; Female; Gingival Diseases; Humans; Hydrogen Peroxide; Male; Middle Aged; Necrosis; Ora

1985
[A case of severe cresol poisoning].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1968, Nov-26, Volume: 44, Issue:49

    Topics: Acidosis; Arrhythmias, Cardiac; Bicarbonates; Blood Vessels; Brain; Bronchi; Coma; Cresols; Edema; E

1968
The prediction of immediate survival after procine hepatic transplantation.
    The Australian and New Zealand journal of surgery, 1974, Volume: 44, Issue:3

    Topics: Acidosis; Animals; Bicarbonates; Liver; Liver Diseases; Liver Transplantation; Lung; Necrosis; Posto

1974
Idiopathic respiratory distress syndrome. Treatment with continuous negative-pressure ventilation.
    American journal of diseases of children (1960), 1973, Volume: 125, Issue:5

    Topics: Acidosis; Bicarbonates; Blood Pressure Determination; Female; Humans; Infant, Newborn; Infarction; K

1973
[Therapeutic hyperosmolarity].
    Annales de medecine interne, 1973, Volume: 124, Issue:3

    Topics: Adult; Bicarbonates; Blood Transfusion; Brain Diseases; Chemical and Drug Induced Liver Injury; Diaz

1973
An evaluation of steroid therapy in aspiration pneumonitis.
    Anesthesiology, 1974, Volume: 40, Issue:2

    Topics: Animals; Bicarbonates; Blood; Bronchi; Carbon Dioxide; Cicatrix; Dogs; Hydrochloric Acid; Hydrogen-I

1974
Intramyocardial carbon dioxide tension. A guide to the safe period of anoxic arrest of the heart.
    The Journal of thoracic and cardiovascular surgery, 1974, Volume: 68, Issue:1

    Topics: Animals; Bicarbonates; Calcium Chloride; Carbon Dioxide; Dogs; Extracorporeal Circulation; Heart Arr

1974
[Lactic acidosis].
    Actualites de physiologie pathologique, 1970, Volume: 3

    Topics: Acidosis; Adolescent; Adult; Aged; Bicarbonates; Diabetic Ketoacidosis; Female; Glucose; Humans; Lac

1970
[Complications of umbilical vein catheterization in low-birth-weight newborn infants. (Review of literature and case report)].
    Minerva pediatrica, 1972, May-05, Volume: 24, Issue:16

    Topics: Acidosis; Anti-Bacterial Agents; Asphyxia Neonatorum; Autopsy; Bicarbonates; Birth Weight; Catheteri

1972
Auxiliary liver perfusion in the pig. Effect of ischaemically damaged livers on recipient animals.
    The Journal of surgical research, 1972, Volume: 13, Issue:4

    Topics: Animals; Bicarbonates; Disseminated Intravascular Coagulation; Electrolytes; Glucose; Heparin; Ische

1972
The role of electrolyte disturbances and extracellular alkalosis in metabolic cardiac necrosis and the preventive effect of amiloride.
    The American journal of cardiology, 1970, Volume: 26, Issue:1

    Topics: Acid-Base Equilibrium; Alkalosis; Animals; Bicarbonates; Carbon Dioxide; Chlorides; Electrolytes; Fe

1970
Respiratory gases of synovial fluids. An approach to synovial tissue circulatory-metabolic imbalance in rheumatoid arthritis.
    The American journal of medicine, 1970, Volume: 49, Issue:2

    Topics: Adult; Arthritis, Reactive; Arthritis, Rheumatoid; Bicarbonates; Biopsy; Blood Gas Analysis; Carbon

1970
[The role of liver necrosis in the pathogenesis of "spontaneous" lactic acidosis].
    Schweizerische medizinische Wochenschrift, 1967, May-27, Volume: 97, Issue:21

    Topics: Acidosis; Aged; Bicarbonates; Female; Humans; Lactates; Liver Diseases; Liver Function Tests; Male;

1967
Hepatic injury associated with tromethamine.
    JAMA, 1968, Jul-08, Volume: 205, Issue:2

    Topics: Acidosis, Respiratory; Bicarbonates; Chemical and Drug Induced Liver Injury; Hemorrhage; Humans; Inf

1968