Page last updated: 2024-10-18

hydrogen carbonate and Multiple Sclerosis

hydrogen carbonate has been researched along with Multiple Sclerosis in 6 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
IBRAHIM, MZ1
BRISCOE, PB1
BAYLISS, OB1
ADAMS, CW1
Bauer, E1
Derfler, K1
Joukhadar, C1
Druml, W1
Boussouf, A1
Gaillard, S1
Stefoski, D1
Davis, FA3
Schauf, CL2
Michael, JA1
Becker, FO1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Filters Useful Life, Metabolic Control, Electrolyte Profile and Acid-base Balance During Regional Anticoagulation With 4% Trisodium Citrate in Patients Undergoing CVVHDF: Effects of Increased Blood Flow[NCT05796661]27 participants (Anticipated)Interventional2023-01-09Recruiting
Calcium Mass Balance and Dialytic Efficiency of a New cITRate-containing and Acetate-free Dialysis flUidS: CITRUS Study[NCT02848937]62 participants (Anticipated)Observational2013-03-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydrogen carbonate and Multiple Sclerosis

ArticleYear
Pathophysiology of multiple sclerosis and related clinical implications.
    Modern treatment, 1970, Volume: 7, Issue:5

    Topics: Action Potentials; Animals; Axons; Bicarbonates; Body Temperature; Calcium; Central Nervous System;

1970

Other Studies

5 other studies available for hydrogen carbonate and Multiple Sclerosis

ArticleYear
THE RELATIONSHIP BETWEEN ENZYME ACTIVITY AND NEUROGLIA IN THE PRODROMAL AND DEMYELINATING STAGES OF CYANIDE ENCEPHALOPATHY IN THE RAT.
    Journal of neurology, neurosurgery, and psychiatry, 1963, Volume: 26

    Topics: Bicarbonates; Blood Chemical Analysis; Brain; Brain Diseases; Corpus Callosum; Cyanides; Demyelinati

1963
Citrate kinetics in patients receiving long-term hemodialysis therapy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 46, Issue:5

    Topics: Acid-Base Imbalance; Adult; Anticoagulants; Bicarbonates; Citrates; Female; Hemodialysis Solutions;

2005
Citrate kinetics in patients receiving long-term hemodialysis therapy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 46, Issue:5

    Topics: Acid-Base Imbalance; Adult; Anticoagulants; Bicarbonates; Citrates; Female; Hemodialysis Solutions;

2005
Citrate kinetics in patients receiving long-term hemodialysis therapy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 46, Issue:5

    Topics: Acid-Base Imbalance; Adult; Anticoagulants; Bicarbonates; Citrates; Female; Hemodialysis Solutions;

2005
Citrate kinetics in patients receiving long-term hemodialysis therapy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 46, Issue:5

    Topics: Acid-Base Imbalance; Adult; Anticoagulants; Bicarbonates; Citrates; Female; Hemodialysis Solutions;

2005
Intracellular pH changes during oligodendrocyte differentiation in primary culture.
    Journal of neuroscience research, 2000, Mar-15, Volume: 59, Issue:6

    Topics: Animals; Bicarbonates; Brain; Carbon Dioxide; Cell Culture Techniques; Cell Differentiation; Chlorid

2000
Acute improvement in exacerbating multiple sclerosis produced by intravenous administration of mannitol.
    Annals of neurology, 1985, Volume: 18, Issue:4

    Topics: Adrenocorticotropic Hormone; Adult; Bicarbonates; Female; Humans; Injections, Intramuscular; Injecti

1985
Treatment for multiple sclerosis.
    The New England journal of medicine, 1973, May-24, Volume: 288, Issue:21

    Topics: Bicarbonates; Calcium; Edetic Acid; Humans; Multiple Sclerosis; Neural Conduction; Sodium

1973