Page last updated: 2024-10-18

hydrogen carbonate and MODS

hydrogen carbonate has been researched along with MODS in 16 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Research Excerpts

ExcerptRelevanceReference
"Fifty critically ill acute renal failure patients have been treated with bicarbonate-CRRT."2.68Bicarbonate dialysate for continuous renal replacement therapy in intensive care unit patients with acute renal failure. ( Leblanc, M; Moreno, L; Paganini, EP; Robinson, OP; Tapolyai, M, 1995)
"Treatment with olprinone attenuated the peritoneal exudation and the migration of polymorphonuclear cells caused by zymosan."1.37Olprinone, a specific phosphodiesterase (PDE)-III inhibitor, reduces the development of multiple organ dysfunction syndrome in mice. ( Bramanti, P; Cuzzocrea, S; Di Paola, R; Esposito, E; Impellizzeri, D; Mazzon, E, 2011)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (50.00)18.2507
2000's6 (37.50)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saleem, M1
Dimeski, G1
Bourne, L1
Coates, P1
Das, S1
Misra, B1
Roul, L1
Minz, NT1
Pattnaik, M1
Baig, MA1
Surbatovic, M1
Radakovic, S1
Jevtic, M1
Filipovic, N1
Romic, P1
Popovic, N1
Jevdjic, J1
Grujic, K1
Djordjevic, D1
Mazzon, E1
Esposito, E1
Di Paola, R1
Impellizzeri, D1
Bramanti, P1
Cuzzocrea, S1
Bunchman, TE1
Maxvold, NJ1
Brophy, PD1
Soysal, DD1
Karaböcüoğlu, M1
Citak, A1
Uçsel, R1
Uzel, N1
Nayir, A1
Dubin, A1
Menises, MM1
Masevicius, FD1
Moseinco, MC1
Kutscherauer, DO1
Ventrice, E1
Laffaire, E1
Estenssoro, E1
Leblanc, M1
Moreno, L1
Robinson, OP1
Tapolyai, M1
Paganini, EP1
Gotloib, L1
Shostak, A1
Lev, A1
Fudin, R1
Jaichenko, J1
Bellomo, R1
Farmer, M1
Boyce, N1
Schaffartzik, W1
Schlichtig, R1
Mehta, N1
Gayowski, TJ1
Meloni, C1
Morosetti, M1
Meschini, L1
Palombo, G1
Latorre, PC1
Taccone-Gallucci, M1
Di Giulio, S1
Casciani, CU1
Aneman, A1
Pettersson, A1
Eisenhofer, G1
Friberg, P1
Holm, M1
von Bothmer, C1
Fändriks, L1
McLean, AG1
Davenport, A1
Cox, D1
Sweny, P1
Clasen, M1
Böhm, R1
Riehl, J1
Gladziwa, U1
Dakshinamurty, KV1
Schacht, B1
Mann, H1
Sieberth, HG1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of a Simplified Protocol for Regional Citrate Anticoagulation in Continuous Venovenous Hemodiafiltration[NCT00583765]20 participants (Actual)Observational2005-04-30Completed
Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill : A Multiple Center Randomized Clinical Trial (BICAR-ICU)[NCT02476253]Phase 3400 participants (Anticipated)Interventional2015-05-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for hydrogen carbonate and MODS

ArticleYear
Bicarbonate dialysate for continuous renal replacement therapy in intensive care unit patients with acute renal failure.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1995, Volume: 26, Issue:6

    Topics: Acute Kidney Injury; Bicarbonates; Female; Hemodialysis Solutions; Humans; Intensive Care Units; Lac

1995
The outcome of critically ill elderly patients with severe acute renal failure treated by continuous hemodiafiltration.
    The International journal of artificial organs, 1994, Volume: 17, Issue:9

    Topics: Acute Kidney Injury; Aged; Bicarbonates; Confidence Intervals; Creatinine; Hemodiafiltration; Humans

1994
Blood purification procedures for acute renal failure: convenient strategy related to clinical conditions.
    Blood purification, 1996, Volume: 14, Issue:3

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Bicarbonates; Female; Hemofiltration; Humans; Male; Mi

1996
Effects of lactate-buffered and lactate-free dialysate in CAVHD patients with and without liver dysfunction.
    Kidney international, 2000, Volume: 58, Issue:4

    Topics: Acid-Base Equilibrium; Acidosis; Acute Kidney Injury; Adult; APACHE; Bicarbonates; Blood Pressure; B

2000
Lactate or bicarbonate for intermittent hemofiltration?
    Contributions to nephrology, 1991, Volume: 93

    Topics: Acidosis, Lactic; Acute Kidney Injury; Bicarbonates; Buffers; Female; Hemodialysis Solutions; Hemofi

1991

Other Studies

11 other studies available for hydrogen carbonate and MODS

ArticleYear
Artifactually elevated serum bicarbonate results caused by elevated serum lactate dehydrogenase concentrations.
    Annals of clinical biochemistry, 2013, Volume: 50, Issue:Pt 4

    Topics: Aged; Artifacts; Bicarbonates; Female; Humans; L-Lactate Dehydrogenase; Multiple Organ Failure

2013
Insulin resistance and beta cell function as prognostic indicator in multi-organ dysfunction syndrome.
    Metabolic syndrome and related disorders, 2009, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Aged; APACHE; Bicarbonates; Blood Glucose; Critical Illness; Disease Progression;

2009
Predictive value of serum bicarbonate, arterial base deficit/excess and SAPS III score in critically ill patients.
    General physiology and biophysics, 2009, Volume: 28 Spec No

    Topics: APACHE; Arteries; Bicarbonates; Critical Illness; Female; Humans; Hydrogen-Ion Concentration; Male;

2009
Olprinone, a specific phosphodiesterase (PDE)-III inhibitor, reduces the development of multiple organ dysfunction syndrome in mice.
    Pharmacological research, 2011, Volume: 64, Issue:1

    Topics: Alanine Transaminase; Alkaline Phosphatase; Amylases; Animals; Apoptosis; Ascitic Fluid; Aspartate A

2011
Pediatric convective hemofiltration: Normocarb replacement fluid and citrate anticoagulation.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 42, Issue:6

    Topics: Adolescent; Anticoagulants; Bicarbonates; Child; Child, Preschool; Citric Acid; Clinical Protocols;

2003
Metabolic disturbances following the use of inadequate solutions for hemofiltration in acute renal failure.
    Pediatric nephrology (Berlin, Germany), 2007, Volume: 22, Issue:5

    Topics: Acidosis; Acute Kidney Injury; Bicarbonates; Child; Fluid Therapy; Glomerular Filtration Rate; Hemof

2007
Comparison of three different methods of evaluation of metabolic acid-base disorders.
    Critical care medicine, 2007, Volume: 35, Issue:5

    Topics: Acid-Base Imbalance; Aged; Albumins; Anions; Area Under Curve; Bicarbonates; Female; Humans; Hydroge

2007
Treatment of surgical and non-surgical septic multiorgan failure with bicarbonate hemodialysis and sequential hemofiltration.
    Intensive care medicine, 1995, Volume: 21, Issue:2

    Topics: Adult; Aged; Bicarbonates; Evaluation Studies as Topic; Female; Hemofiltration; Humans; Male; Middle

1995
[Intramucosal pCO2 measurement: contra].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1995, Volume: 30 Suppl 1

    Topics: Acid-Base Equilibrium; Bicarbonates; Carbon Dioxide; Critical Care; Gastric Mucosa; Humans; Intestin

1995
Tissue-arterial PCO2 difference is a better marker of ischemia than intramural pH (pHi) or arterial pH-pHi difference.
    Journal of critical care, 1996, Volume: 11, Issue:2

    Topics: Acid-Base Equilibrium; Animals; Bicarbonates; Carbon Dioxide; Diagnosis, Differential; Dogs; Gastric

1996
Sympathetic and renin-angiotensin activation during graded hypovolemia in pigs: impact on mesenteric perfusion and duodenal mucosal function.
    Shock (Augusta, Ga.), 1997, Volume: 8, Issue:5

    Topics: Angiotensin II; Animals; Bicarbonates; Duodenum; Enalaprilat; Guanethidine; Hemodynamics; Intestinal

1997