Page last updated: 2024-10-18

hydrogen carbonate and Lung Neoplasms

hydrogen carbonate has been researched along with Lung Neoplasms in 14 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Lung Neoplasms: Tumors or cancer of the LUNG.

Research Excerpts

ExcerptRelevanceReference
"Using our mouse model for metastatic breast cancer (MDA-MB-231), we designed an interventional survival study where tumor bearing mice received bicarbonate, DCA, or DCA-bicarbonate (DB) therapies chronically."1.37Bicarbonate and dichloroacetate: evaluating pH altering therapies in a mouse model for metastatic breast cancer. ( Martin, NK; Robey, IF, 2011)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's3 (21.43)18.2507
2000's0 (0.00)29.6817
2010's5 (35.71)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Lee, D1
Lee, PC1
Hong, JH2
Shin, DM1
Kim, HJ1
Kim, J1
Hu, Z1
Cai, L1
Li, K1
Choi, E1
Faubert, B1
Bezwada, D1
Rodriguez-Canales, J1
Villalobos, P1
Lin, YF1
Ni, M1
Huffman, KE1
Girard, L1
Byers, LA1
Unsal-Kacmaz, K1
Peña, CG1
Heymach, JV1
Wauters, E1
Vansteenkiste, J1
Castrillon, DH1
Chen, BPC1
Wistuba, I1
Lambrechts, D1
Xu, J1
Minna, JD1
DeBerardinis, RJ1
Sebastian, N1
Wu, T1
Driscoll, E1
Willers, H1
Kelly, S1
Musunuru, HB1
Mo, X1
Tan, Y1
Bazan, J1
Haglund, K1
Xu-Welliver, M1
Baschnagel, AM1
Ju, A1
Keane, F1
Williams, TM1
Ručka, Z1
Koutná, I1
Tesařová, L1
Potěšilová, M1
Stejskal, S1
Simara, P1
Vaňhara, P1
DoleŽel, J1
Zvoníček, V1
Coufal, O1
Capov, I1
Chen, EY1
Yang, N1
Quinton, PM1
Chin, WC1
Robey, IF1
Martin, NK1
Harrington, JT1
Colman, LK1
Baker, TM1
Gibney, E1
Elia, M1
Jebb, SA1
Murgatroyd, P1
Jennings, G1
Illek, B1
Tam, AW1
Fischer, H1
Machen, TE1
Watine, J1
Charet, JC1
Krapf, R1
Cogan, MG1
Bondy, PK1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Comparative, Multicenter and Randomized Study Evaluating the Safety and Efficacy of RESPIMER® Netiflow® Versus Saline Solutions During Nasal Irrigation Following Bilateral Ethmoidectomy in the Treatment of Nasal Polyposis.[NCT02559284]189 participants (Actual)Interventional2015-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydrogen carbonate and Lung Neoplasms

ArticleYear
[Primary small-cell bronchial cancer: value of serum tumor markers in the prognostic evaluation].
    Presse medicale (Paris, France : 1983), 1999, Sep-25, Volume: 28, Issue:28

    Topics: Bicarbonates; Biomarkers, Tumor; Carcinoma, Small Cell; Humans; Lung Neoplasms; Phosphopyruvate Hydr

1999

Trials

1 trial available for hydrogen carbonate and Lung Neoplasms

ArticleYear
Intravenous insulin therapy during lung resection does not affect lung function or surfactant proteins.
    BMC pulmonary medicine, 2014, Oct-02, Volume: 14

    Topics: Acid-Base Imbalance; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Bicarbonates; Bloo

2014

Other Studies

12 other studies available for hydrogen carbonate and Lung Neoplasms

ArticleYear
Estrogen treatment reduced oxalate transporting activity and enhanced migration through the involvement of SLC26A6 in lung cancer cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2022, Volume: 82

    Topics: Antiporters; Bicarbonates; Estradiol; Estrogens; Female; Humans; Lung Neoplasms; Oxalates; Sulfate T

2022
Trafficking of carbonic anhydrase 12 and bicarbonate transporters by histamine stimulation mediates intracellular acidic scenario in lung cancer cells.
    Journal of enzyme inhibition and medicinal chemistry, 2023, Volume: 38, Issue:1

    Topics: Bicarbonates; Carbonic Anhydrases; Histamine; Humans; Lung Neoplasms

2023
CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.
    Nature, 2017, 06-01, Volume: 546, Issue:7656

    Topics: Ammonia; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Bicarbonates;

2017
Pre-treatment serum bicarbonate predicts for primary tumor control after stereotactic body radiation therapy in patients with localized non-small cell lung cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2019, Volume: 140

    Topics: Aged; Aged, 80 and over; Bicarbonates; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasm

2019
A new role for bicarbonate in mucus formation.
    American journal of physiology. Lung cellular and molecular physiology, 2010, Volume: 299, Issue:4

    Topics: Adenocarcinoma; Bicarbonates; Calcium; Exocytosis; Humans; Lung Neoplasms; Mucins; Mucus; Pulmonary

2010
Bicarbonate and dichloroacetate: evaluating pH altering therapies in a mouse model for metastatic breast cancer.
    BMC cancer, 2011, Jun-10, Volume: 11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Bicarbonates; Breast Neoplasms; Cell Hypoxia;

2011
Metabolic alkalosis.
    Kidney international, 1984, Volume: 26, Issue:1

    Topics: Alkalosis; Animals; Bicarbonates; Carbon Dioxide; Carcinoma, Small Cell; Chlorides; Female; Glomerul

1984
Lactic acidosis with extensive oat cell carcinoma of the lung--not necessarily a poor prognostic sign: case report.
    Military medicine, 1983, Volume: 148, Issue:5

    Topics: Acidosis; Antineoplastic Agents; Bicarbonates; Carcinoma, Small Cell; Humans; Lactates; Liver Neopla

1983
Total energy expenditure in patients with small-cell lung cancer: results of a validated study using the bicarbonate-urea method.
    Metabolism: clinical and experimental, 1997, Volume: 46, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Alanine Transaminase; Alkaline Phosphatase; Bicarbonates; Bilirubin;

1997
Anion selectivity of apical membrane conductance of Calu 3 human airway epithelium.
    Pflugers Archiv : European journal of physiology, 1999, Volume: 437, Issue:6

    Topics: Adenocarcinoma; Anions; Bicarbonates; Cell Membrane; Cell Membrane Permeability; Cyclic AMP; Cystic

1999
Hyperkalemia suppresses the renal adaptation to chronic respiratory acidosis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1989, Volume: 14, Issue:2

    Topics: Acidosis, Respiratory; Adaptation, Physiological; Ammonia; Bicarbonates; Carcinoma, Squamous Cell; H

1989
Some 'pseudo' and some true endocrine syndromes in cancer.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:1

    Topics: Adrenocorticotropic Hormone; Alkalosis; Bicarbonates; Breast Neoplasms; Calcium; Carcinoma, Bronchog

1974