Page last updated: 2024-10-18

hydrogen carbonate and Lung Diseases, Obstructive

hydrogen carbonate has been researched along with Lung Diseases, Obstructive in 37 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Lung Diseases, Obstructive: Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.

Research Excerpts

ExcerptRelevanceReference
"During an incremental exercise test, three consequences of the onset of anaerobic metabolism can be observed: rise in blood lactate (lactate threshold, LT); fall in standard bicarbonate (lactic acidosis threshold, LAT); nonlinear increase in CO2 output (V-slope gas exchange threshold, GET)."7.68Comparison of gas exchange, lactate, and lactic acidosis thresholds in patients with chronic obstructive pulmonary disease. ( Appendini, L; Carone, M; Casaburi, R; Donner, CF; Patessio, A; Wasserman, K, 1993)
"During an incremental exercise test, three consequences of the onset of anaerobic metabolism can be observed: rise in blood lactate (lactate threshold, LT); fall in standard bicarbonate (lactic acidosis threshold, LAT); nonlinear increase in CO2 output (V-slope gas exchange threshold, GET)."3.68Comparison of gas exchange, lactate, and lactic acidosis thresholds in patients with chronic obstructive pulmonary disease. ( Appendini, L; Carone, M; Casaburi, R; Donner, CF; Patessio, A; Wasserman, K, 1993)
"Acetate-induced hypoxemia was associated with reduced respiratory CO2 excretion and hypoventilation but PaCO2 did not change."1.28Pulmonary gas exchange during dialysis in patients with obstructive lung disease. ( Diamond, SM; Henrich, WL; Pitcher, WD, 1989)
"Patients with mixed chronic respiratory acidosis and metabolic alkalosis constitute a common subgroup of patients with chronic obstructive lung disease and carbon dioxide retention; these patients benefit from correction of the metabolic alkalosis."1.26Effect of metabolic alkalosis on respiratory function in patients with chronic obstructive lung disease. ( Bear, R; Feldman, R; Goldstein, M; Halperin, M; Hammeke, M; Handelsman, S; Ho, M; Phillipson, E, 1977)
"Nitroglycerin was administered to a group of 11 patients with chronic obstructive pulmonary disease in a dose of 0."1.25The effect of nitroglycerin in gas exchange on chronic obstructive pulmonary disease. ( Chick, TW; Jenne, JW; Kochukoshy, KN, 1975)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199030 (81.08)18.7374
1990's6 (16.22)18.2507
2000's1 (2.70)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lang, SM1
Becker, A1
Fischer, R1
Huber, RM1
Schiffl, H1
Skatrud, JB1
Berssenbrugge, AD1
Patakas, D2
Sproule, B1
Jones, D1
Phillipow, L1
Ziutas, G1
Littlejohn, A2
Bowles, F2
Milhorn, HT1
Kawakami, Y2
Kamishima, K1
Yoshikawa, T1
Shida, A1
Asanuma, Y1
Kishi, F1
Irie, T1
Murao, M1
Honda, Y1
Sengül, R1
Seven, A1
Celikoğlu, F1
Candan, G1
Hatemi, H1
Celikoğlu, S1
Salejee, I1
Tarasiuk, A1
Reder, I1
Scharf, SM1
Patessio, A1
Casaburi, R1
Carone, M1
Appendini, L1
Donner, CF1
Wasserman, K2
Alfaro, V1
Torras, R1
Ibáñez, J1
Palacios, L1
Kondo, T1
Taniguchi, N1
ide, H1
Saito, K1
Bear, R1
Goldstein, M1
Phillipson, E1
Ho, M1
Hammeke, M1
Feldman, R1
Handelsman, S1
Halperin, M1
Kochukoshy, KN1
Chick, TW1
Jenne, JW1
Fumagalli, G1
Ferrara, A1
Pasargiklian, M1
Miller, PD1
Berns, AS1
Louridas, G1
Argyropoulou, P1
Stavropoulos, C1
Belman, MJ1
Epstein, LJ1
Doornbos, D1
Elashoff, JD1
Koerner, SK1
Mohsenifar, Z1
Hwang, TL1
Huang, SL1
Chen, MF1
Porro, F1
Figini, G1
Curti, L1
Fanelli, M1
Pitcher, WD1
Diamond, SM1
Henrich, WL1
Skaredoff, MN1
York, K1
Wahl, RL1
Fiaccadori, E2
Del Canale, S2
Arduini, U2
Antonucci, C2
Coffrini, E2
Vitali, P2
Meley, R1
Guariglia, A2
Altschuler, SL1
Pande, JN1
Sridharan, SK1
Guleria, JS1
Gottlieb, LS1
Balchum, OJ1
Ingram, RH1
Miller, RB1
Tate, LA1
Lopez-Majano, V1
Dutton, RE1
Golden, GT1
Litwiller, RW1
Heironimus, TW1
Collier, C1
Lugliani, R1
Whipp, BJ1
Winter, B1
Tanaka, KR1
Kettel, LJ1
Diener, CF1
Morse, JO1
Stein, HF1
Burrows, B1
Tuller, MA1
Mehdi, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Automated Administration of Oxygen Using the FreeO2 Device in Ambulances for COPD and Trauma Patients: A Feasibility Study[NCT03696563]100 participants (Anticipated)Interventional2021-09-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for hydrogen carbonate and Lung Diseases, Obstructive

ArticleYear
Effect of sleep state and chemical stimuli on breathing.
    Progress in clinical and biological research, 1983, Volume: 136

    Topics: Acetazolamide; Bicarbonates; Carbon Dioxide; Chronic Disease; Humans; Lung Diseases, Obstructive; Me

1983
Oxygen therapy in pulmonary disease. Oxygen use and toxicity.
    The Medical clinics of North America, 1973, Volume: 57, Issue:4

    Topics: Acidosis, Respiratory; Bicarbonates; Blood Gas Analysis; Heart Defects, Congenital; Humans; Hydrogen

1973

Other Studies

35 other studies available for hydrogen carbonate and Lung Diseases, Obstructive

ArticleYear
Acute effects of hemodialysis on lung function in patients with end-stage renal disease.
    Wiener klinische Wochenschrift, 2006, Volume: 118, Issue:3-4

    Topics: Adult; Aged; Aged, 80 and over; Bicarbonates; Biocompatible Materials; Female; Humans; Kidney Failur

2006
Cerebral blood flow, oxygen, carbon dioxide tensions, and blood bicarbonate in controlling drive and timing in patients with chronic obstructive pulmonary diseases.
    Respiration; international review of thoracic diseases, 1984, Volume: 46, Issue:1

    Topics: Adult; Aged; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Cerebrovascular Circulation; Female;

1984
Studies on the physiopathology of chronic obstructive pulmonary disease in the horse. IV. Blood gas and acid-base values at rest.
    The Onderstepoort journal of veterinary research, 1981, Volume: 48, Issue:1

    Topics: Acid-Base Equilibrium; Animals; Bicarbonates; Blood Pressure; Carbon Dioxide; Horse Diseases; Horses

1981
Studies on the physiopathology of chronic obstructive pulmonary disease in the horse. V. Blood gas and acid-base values during exercise.
    The Onderstepoort journal of veterinary research, 1981, Volume: 48, Issue:4

    Topics: Animals; Bicarbonates; Carbon Dioxide; Hematocrit; Hemoglobins; Horse Diseases; Horses; Hydrogen-Ion

1981
Understanding arterial blood gases.
    American family physician, 1980, Volume: 21, Issue:3

    Topics: Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Bicarbonate

1980
[Pathophysiologic significance of protein buffer value in patients with obstructive pulmonary disease (author's transl)].
    Kokyu to junkan. Respiration & circulation, 1980, Volume: 28, Issue:2

    Topics: Bicarbonates; Blood Proteins; Hemoglobins; Humans; Hydrogen-Ion Concentration; Lung Diseases, Obstru

1980
Erythrocyte sorbitol concentration in relation to blood gas tensions and acid-base balance parameters.
    Biochemical Society transactions, 1993, Volume: 21 ( Pt 3), Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Bicarbonates; Blood Glucose; Carbon Dioxide; Electrolytes; Erythrocy

1993
Chronic upper airway obstruction produces right but not left ventricular hypertrophy in rats.
    The American review of respiratory disease, 1993, Volume: 148, Issue:5

    Topics: Animals; Bicarbonates; Carbon Dioxide; Female; Hemoglobins; Hypertrophy, Left Ventricular; Hypertrop

1993
Comparison of gas exchange, lactate, and lactic acidosis thresholds in patients with chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1993, Volume: 148, Issue:3

    Topics: Acidosis, Lactic; Anaerobic Threshold; Bicarbonates; Carbon Dioxide; Exercise Test; Humans; Lactates

1993
A physical-chemical analysis of the acid-base response to chronic obstructive pulmonary disease.
    Canadian journal of physiology and pharmacology, 1996, Volume: 74, Issue:11

    Topics: Acid-Base Equilibrium; Aged; Bicarbonates; Carbon Dioxide; Electrolytes; Female; Humans; Hydrogen-Io

1996
Human erythrocyte carbonic anhydrase B and C in chronic obstructive lung disease.
    The Tohoku journal of experimental medicine, 1975, Volume: 117, Issue:4

    Topics: Bicarbonates; Carbon Dioxide; Carbonic Anhydrases; Erythrocytes; Female; Humans; Hydrogen-Ion Concen

1975
Effect of metabolic alkalosis on respiratory function in patients with chronic obstructive lung disease.
    Canadian Medical Association journal, 1977, Oct-22, Volume: 117, Issue:8

    Topics: Acetazolamide; Acidosis, Respiratory; Aged; Alkalosis; Ammonium Chloride; Bicarbonates; Blood Gas An

1977
The effect of nitroglycerin in gas exchange on chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1975, Volume: 111, Issue:2

    Topics: Acid-Base Equilibrium; Anthropometry; Bicarbonates; Blood; Blood Pressure; Carbon Dioxide; Chronic D

1975
[Changes in the acid-base equilibrium and the water-electrolyte balance during maximum aerobic work in patients with chronic broncho-pulmonary disease].
    Minerva medica, 1979, Jan-07, Volume: 70, Issue:1

    Topics: Acid-Base Equilibrium; Bicarbonates; Ethylenediamines; Humans; Lung Diseases, Obstructive; Oxygen In

1979
Acute metabolic alkalosis perpetuating hypercarbia. A role for acetazolamide in chronic obstructive pulmonary disease.
    JAMA, 1977, Nov-28, Volume: 238, Issue:22

    Topics: Acetazolamide; Aged; Alkalosis; Bicarbonates; Carbon Dioxide; Chronic Disease; Diuretics; Female; He

1977
Respiratory drive in patients with chronic obstructive pulmonary disease.
    Respiration; international review of thoracic diseases, 1978, Volume: 36, Issue:4

    Topics: Bicarbonates; Blood Gas Analysis; Bronchitis; Emphysema; Humans; Hypercapnia; Lung Diseases, Obstruc

1978
Noninvasive determinations of the anaerobic threshold. Reliability and validity in patients with COPD.
    Chest, 1992, Volume: 102, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anaerobic Threshold; Bicarbonates; Blood Gas Analysis; Exercise Test

1992
Effects of intravenous fat emulsion on respiratory failure.
    Chest, 1990, Volume: 97, Issue:4

    Topics: Bicarbonates; Carbon Dioxide; Fat Emulsions, Intravenous; Humans; Hydrogen-Ion Concentration; Lung D

1990
[Correlation between hemorheological and blood gas analytical indices in hypoxic-hypercapnic respiratory insufficiency].
    La Ricerca in clinica e in laboratorio, 1989, Volume: 19 Suppl 1

    Topics: Adult; Bicarbonates; Blood Gas Analysis; Blood Viscosity; Carbon Dioxide; Female; Humans; Hydrogen-I

1989
Pulmonary gas exchange during dialysis in patients with obstructive lung disease.
    Chest, 1989, Volume: 96, Issue:5

    Topics: Acetates; Bicarbonates; Dialysis Solutions; Humans; Hypoxia; Kidney Failure, Chronic; Lung Diseases,

1989
A computerized system for rapid interpretation of acid/base disorders.
    International journal of bio-medical computing, 1986, Volume: 18, Issue:3-4

    Topics: Acid-Base Imbalance; Bicarbonates; Carbon Dioxide; Child; Computers; Diabetic Ketoacidosis; Diagnosi

1986
The lung and fluid-electrolyte and acid-base imbalances.
    The Nursing clinics of North America, 1987, Volume: 22, Issue:4

    Topics: Acid-Base Imbalance; Acidosis, Respiratory; Alkalosis, Respiratory; Bicarbonates; Carbon Dioxide; Hu

1987
Gastric xenon trapping mimicking COPD: recognition using an effervescent agent.
    European journal of nuclear medicine, 1986, Volume: 12, Issue:3

    Topics: Adult; Antacids; Bicarbonates; Citrates; Citric Acid; Diagnosis, Differential; Drug Combinations; Ga

1986
Intracellular acid-base and electrolyte metabolism in skeletal muscle of patients with chronic obstructive lung disease and acute respiratory failure.
    Clinical science (London, England : 1979), 1986, Volume: 71, Issue:6

    Topics: Acid-Base Equilibrium; Adult; Aged; Bicarbonates; Body Water; Electrolytes; Female; Humans; Hydrogen

1986
[Intracellular buffering and chronic acidotic states. Findings in hypercapnic respiratory insufficiency and renal failure].
    Recenti progressi in medicina, 1986, Volume: 77, Issue:10

    Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Bicarbonates; Biopsy; Humans; Hypercapnia; K

1986
Arterial desaturation after sodium bicarbonate therapy in bronchial asthma.
    The American review of respiratory disease, 1973, Volume: 107, Issue:2

    Topics: Airway Resistance; Asthma; Bicarbonates; Humans; Lung; Lung Compliance; Lung Diseases, Obstructive;

1973
Course of chronic obstructive pulmonary disease following first onset of respiratory failure.
    Chest, 1973, Volume: 63, Issue:1

    Topics: Adult; Aged; Bicarbonates; Carbon Dioxide; Chronic Disease; Disability Evaluation; Female; Heart Fai

1973
Acid-base response to acute carbon dioxide changes in chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1973, Volume: 108, Issue:2

    Topics: Acid-Base Equilibrium; Bicarbonates; Carbon Dioxide; Humans; Hydrogen-Ion Concentration; Lung Diseas

1973
Regulation of respiration during oxygen breathing in chronic obstructive lung disease.
    The American review of respiratory disease, 1973, Volume: 108, Issue:2

    Topics: Acidosis; Airway Resistance; Arteries; Bicarbonates; Carbon Dioxide; Carbon Monoxide; Chronic Diseas

1973
The interpretation of arterial blood gases: a concise guide for clinicians.
    Southern medical journal, 1973, Volume: 66, Issue:9

    Topics: Acid-Base Equilibrium; Acidosis; Adolescent; Adult; Alkalosis; Arteries; Bicarbonates; Blood Gas Ana

1973
Letter: Acid-base response in COPD.
    The American review of respiratory disease, 1974, Volume: 109, Issue:5

    Topics: Acid-Base Equilibrium; Bicarbonates; Carbon Dioxide; Humans; Lung Diseases, Obstructive

1974
The role of the carotid body in erythropoiesis in man.
    The New England journal of medicine, 1971, 11-11, Volume: 285, Issue:20

    Topics: Aged; Asthma; Bicarbonates; Bloodletting; Carbon Dioxide; Carotid Body; Erythrocyte Count; Erythropo

1971
Treatment of acute respiratory acidosis in chronic obstructive lung disease.
    JAMA, 1971, Sep-13, Volume: 217, Issue:11

    Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Acute Disease; Adult; Aged; Bicarbonates; Carbon Dioxi

1971
Compensatory hypoventilation and hypercapnia in primary metabolic alkalosis. Report of three cases.
    The American journal of medicine, 1971, Volume: 50, Issue:3

    Topics: Aged; Alkalosis; Bicarbonates; Chlorothiazide; Dehydration; Female; Humans; Hypercapnia; Hypokalemia

1971
Pharmacologic agents.
    Aspen Emphysema Conference, 1965, Volume: 8

    Topics: Acetylcysteine; Acidosis, Respiratory; Anticoagulants; Bicarbonates; Bronchodilator Agents; Chymotry

1965