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hydrogen carbonate and Leukemia

hydrogen carbonate has been researched along with Leukemia in 14 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

Research Excerpts

ExcerptRelevanceReference
"We report three infants with acute leukemia and hyperleukocytosis in whom intravenous hydration, alkalinization, and allopurinol therapy alone produced rapid and dramatic decreases in the peripheral leukocyte count."8.78Management of leukemic hyperleukocytosis with hydration, urinary alkalinization, and allopurinol. Are cranial irradiation and invasive cytoreduction necessary? ( Bruggers, CS; Friedman, HS; Kurtzberg, J; Nelson, SC, 1993)
"We report three infants with acute leukemia and hyperleukocytosis in whom intravenous hydration, alkalinization, and allopurinol therapy alone produced rapid and dramatic decreases in the peripheral leukocyte count."4.78Management of leukemic hyperleukocytosis with hydration, urinary alkalinization, and allopurinol. Are cranial irradiation and invasive cytoreduction necessary? ( Bruggers, CS; Friedman, HS; Kurtzberg, J; Nelson, SC, 1993)
" During 29 courses (88%) of treatment, polyuria, glucosuria, and/or transient changes in the serum concentrations of bicarbonate or phosphorus were detected."3.665-Azacytidine and renal tubular dysfunction. ( Bloomfield, CD; Collins, AJ; Peterson, BA; Vogelzang, NJ, 1981)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199013 (92.86)18.7374
1990's1 (7.14)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HEYN, R1
NEWTON, W1
CARTER, R1
RIESELBACH, RE1
BENTZEL, CJ1
COTLOVE, E1
FREI, E1
FREIREICH, EJ1
Peterson, BA1
Collins, AJ1
Vogelzang, NJ1
Bloomfield, CD1
Engelhardt, R1
von der Thann, M1
Löhr, GW1
Nelson, SC1
Bruggers, CS1
Kurtzberg, J1
Friedman, HS1
Fuchs, D1
Hermann, J1
Zintl, F1
Plenert, W1
Masera, G1
Carnelli, V1
Corbella, E1
Uderzo, C1
Sugiura, Y1
Fujioka, S1
Yoshida, S1
Ladoux, A1
Krawice, I1
Cragoe, EJ1
Abita, JP1
Frelin, C1
Wainer, RA1
Wiernik, PH1
Thompson, WL1
Pochedly, C1
Benvenisti, DS1
Sherwood, LM1
Heinemann, HO1
Oliva, PB1
Perret, C1

Reviews

3 reviews available for hydrogen carbonate and Leukemia

ArticleYear
Management of leukemic hyperleukocytosis with hydration, urinary alkalinization, and allopurinol. Are cranial irradiation and invasive cytoreduction necessary?
    The American journal of pediatric hematology/oncology, 1993, Volume: 15, Issue:3

    Topics: Allopurinol; Bicarbonates; Female; Fluid Therapy; Humans; Infant; Leukemia; Leukocytosis; Male; Prec

1993
Hypercalcemic crisis in acute leukemia.
    The American journal of medicine, 1969, Volume: 46, Issue:6

    Topics: Acute Disease; Arabinose; Bicarbonates; Blood; Blood Urea Nitrogen; Bone Marrow Examination; Calcium

1969
Lactic acidosis.
    The American journal of medicine, 1970, Volume: 48, Issue:2

    Topics: Acidosis; Alcoholic Intoxication; Anemia; Animals; Bicarbonates; Cardiac Output; Diabetes Mellitus;

1970

Other Studies

11 other studies available for hydrogen carbonate and Leukemia

ArticleYear
ELDERFIELD PYRIMIDINE MUSTARD (NSC-23436) IN ACUTE LEUKEMIA IN CHILDREN--A PHASE I STUDY.
    Cancer chemotherapy reports, 1963, Volume: 33

    Topics: Animals; Bicarbonates; Dogs; Hodgkin Disease; Leukemia; Leukemia L1210; Leukopenia; Mice; Mustard Pl

1963
URIC ACID EXCRETION AND RENAL FUNCTION IN THE ACUTE HYPERURICEMIA OF LEUKEMIA. PATHOGENESIS AND THERAPY OF URIC ACID NEPHROPATHY.
    The American journal of medicine, 1964, Volume: 37

    Topics: Acetazolamide; Bicarbonates; Blood; Carbon Isotopes; Drug Therapy; Fluids and Secretions; Hippurates

1964
5-Azacytidine and renal tubular dysfunction.
    Blood, 1981, Volume: 57, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Azacitidine; Bicarbonates; Glycosuria; Humans; Kidney Tubule

1981
[Prevention of acute urate nephropathy].
    Die Medizinische Welt, 1980, Volume: 31, Issue:40

    Topics: Acute Disease; Adolescent; Adult; Aged; Allopurinol; Antineoplastic Agents; Bicarbonates; Drug Thera

1980
[Basic therapy in children with leukemia and a malignant tumors. II].
    Kinderarztliche Praxis, 1978, Volume: 46, Issue:3

    Topics: Allopurinol; Anaphylaxis; Anemia; Antibiotics, Antineoplastic; Bicarbonates; Blood Transfusion; Chil

1978
[Antiblastic therapy and cytolysis in infantile leukemia].
    Minerva medica, 1975, Jul-28, Volume: 66, Issue:52

    Topics: Allopurinol; Antineoplastic Agents; Anuria; Bicarbonates; Child; Child, Preschool; Disseminated Intr

1975
Biosynthesis of pyrimidine nucleotides in human leukemic cells.
    Japanese journal of cancer research : Gann, 1986, Volume: 77, Issue:7

    Topics: Adult; Aged; Bicarbonates; Cytidine Deaminase; DNA, Neoplasm; Female; Humans; Leukemia; Male; Middle

1986
Properties of the Na+-dependent Cl-/HCO3- exchange system in U937 human leukemic cells.
    European journal of biochemistry, 1987, Dec-30, Volume: 170, Issue:1-2

    Topics: Bicarbonates; Carrier Proteins; Cell Line; Chloride-Bicarbonate Antiporters; Chlorides; Humans; Hydr

1987
Metabolic and therapeutic studies of a patient with acute leukemia and severe lactic acidosis of prolonged duration.
    The American journal of medicine, 1973, Volume: 55, Issue:2

    Topics: Acidosis; Adult; Bicarbonates; Blood Glucose; Carbon Dioxide; Chronic Disease; Humans; Hydrogen-Ion

1973
Hyperuricemia in leukemia and lymphoma.
    Postgraduate medicine, 1974, Volume: 55, Issue:6

    Topics: Acetazolamide; Acute Kidney Injury; Allopurinol; Antineoplastic Agents; Bicarbonates; Crystallizatio

1974
[Lactic acidosis].
    Actualites de physiologie pathologique, 1970, Volume: 3

    Topics: Acidosis; Adolescent; Adult; Aged; Bicarbonates; Diabetic Ketoacidosis; Female; Glucose; Humans; Lac

1970