hydrogen carbonate has been researched along with Lactic Acidosis in 148 studies
Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "L-lactic acidosis (L-LA) is the most common cause of metabolic acidosis in the critical care setting, which has been associated with a large increase in mortality." | 9.05 | L-lactic acidosis: pathophysiology, classification, and causes; emphasis on biochemical and metabolic basis. ( Halperin, ML; Kamel, KS; Oh, MS, 2020) |
| "Lactic acidosis in metformin use is a widely recognised but rare side effect." | 8.84 | Reality of severe metformin-induced lactic acidosis in the absence of chronic renal impairment. ( Bosch, FH; Bruijstens, LA; Buscher-Jungerhans, PM; van Luin, M, 2008) |
| "This article reviews the current body of knowledge regarding lactic acidosis in critically ill patients." | 8.78 | Lactic acidosis in critical illness. ( Falk, JL; Mizock, BA, 1992) |
| "Metformin-associated lactic acidosis (MALA) is a rare but life-threatening condition." | 8.12 | A patient with severe metformin-associated lactic acidosis complicated by acute coronary syndrome: a case report. ( Ahmed, A; Gudowski, C; Mammadova, N; Pliquett, RU; Shkodivskyi, P; Soukup, J, 2022) |
| "Metformin-associated lactic acidosis (MALA) carries a high mortality rate." | 7.96 | Metformin-associated lactic acidosis: reinforcing learning points. ( Creagh, F; Goonoo, MS; Morris, R; Raithatha, A, 2020) |
| "This study aims to determine whether there is a relationship between nausea level and lactic acidosis during recovery from sprinting." | 7.91 | Role of lactic acidosis as a mediator of sprint-mediated nausea. ( Chivers, PT; Cripps, AJ; Fournier, PA; Merrells, RJ, 2019) |
| "Metformin-associated lactic acidosis is a severe and infrequent adverse event." | 7.85 | [Metformin-associated lactic acidosis. Report of one case]. ( Dreyse, J; Orozco, R; Pezzani, MJ; Quintana, F; Regueira, T; Soto, L, 2017) |
| " Two cases of lactic acidosis due to ingestion of high dose metformin for suicidal purposes have been presented here; in both cases, clinical improvement was seen with bicarbonate hemodialysis." | 7.77 | Dialysis therapy for lactic acidosis caused by metformin intoxication: presentation of two cases. ( Aytemiz, E; Begenik, H; Emre, H; Erkoc, R; Ozturk, M; Soyoral, YU, 2011) |
| "Metformin-associated lactic acidosis is a rare and serious complication of biguanide treatment." | 7.75 | Metformin-associated lactic acidosis: a prognostic and therapeutic study. ( Fourrier, F; Houdret, N; Nseir, S; Seidowsky, A, 2009) |
| "Metformin-associated lactic acidosis is commonly accompanied with acute kidney injury." | 7.75 | Impact of acute kidney injury on metformin-associated lactic acidosis. ( Wen, YK, 2009) |
| "The effects of Carbicarb, sodium bicarbonate, and sodium chloride on arterial blood gases, lactate concentrations, hemodynamics, and myocardial intracellular pH were compared in hypoxic lactic acidosis with controlled carbon dioxide elimination." | 7.68 | Carbicarb, sodium bicarbonate, and sodium chloride in hypoxic lactic acidosis. Effect on arterial blood gases, lactate concentrations, hemodynamic variables, and myocardial intracellular pH. ( Levin, DL; McDonald, GG; Nunnally, RL; Rhee, KH; Toro, LO, 1993) |
| " Thus we investigated the effect of lactic acidosis and two proposed treatments on myocardial energetics and intracellular pH in anesthetized living rats." | 7.68 | Lactic acidosis: effect of treatment on intracellular pH and energetics in living rat heart. ( Barrett, E; Gore, JC; Greene, R; Majumdar, S; Zahler, R, 1992) |
| "During an incremental exercise test, three consequences of the onset of anaerobic metabolism can be observed: rise in blood lactate (lactate threshold, LT); fall in standard bicarbonate (lactic acidosis threshold, LAT); nonlinear increase in CO2 output (V-slope gas exchange threshold, GET)." | 7.68 | Comparison of gas exchange, lactate, and lactic acidosis thresholds in patients with chronic obstructive pulmonary disease. ( Appendini, L; Carone, M; Casaburi, R; Donner, CF; Patessio, A; Wasserman, K, 1993) |
| "Lactic acidosis is seen frequently after severe anoxia and circulatory failure." | 7.67 | Effect of dichloroacetate in the treatment of anoxic lactic acidosis in dogs. ( Caputo, G; Delgado Paredes, C; Egler, J; Fleisher, G; Schaible, D; Sheikh, A; Swedlow, D, 1986) |
| "We report two diabetic patients who developed lactic acidosis following the use of Buformin." | 7.67 | [Lactic acidosis in diabetic patients associated with buformin]. ( Díaz, RA; Hernández, G; Huidobro, F; Jimenez, R; Pérez, H; Torres, H; Videla, C, 1989) |
| "We studied the use of sodium bicarbonate administration in a canine model of hemorrhagic shock to determine its effect on hemodynamics, arterial and venous blood gases, respiratory gases, and blood lactate levels." | 7.67 | Effects of sodium bicarbonate in canine hemorrhagic shock. ( Benjamin, E; Gentili, DR; Iberti, TJ; Katz, DP; Kelly, KM; Premus, G; Rosen, M, 1988) |
| "Lactic acidosis in diabetics on metformin therapy is rare but still associated with poor prognosis." | 7.67 | Bicarbonate haemodialysis: an adequate treatment for lactic acidosis in diabetics treated by metformin. ( Coevoet, B; Debussche, X; Dkissi, H; Fournier, A; Lalau, JD; Quichaud, J; Temperville, B; Tolani, M; Westeel, PF, 1987) |
| "The use of sodium bicarbonate to treat metabolic acidosis is intuitive, yet data suggest that not all patients benefit from this therapy." | 5.41 | A Review of Bicarbonate Use in Common Clinical Scenarios. ( Birch, A; Gupta, A; Holgren, S; Malhotra, A; Pearce, A; Sobel, J; Tainter, C; Wardi, G, 2023) |
| "Serum lactic acidosis is characterized by a pH less than 7." | 5.27 | Comparison of sodium bicarbonate with dichloroacetate treatment of hyperlactatemia and lactic acidosis in the ischemic rat. ( Biros, MH; Dimlich, RV; Kaplan, J; Widman, DW, 1988) |
| "To verify the efficacy and absence of risk attributable to therapy with alkaline solutions for correction of lactic acidosis and to demonstrate the usefulness of L-carnitine in converting lactate into pyruvate in conditions of good blood oxygenation." | 5.07 | [Intraoperative lactic acidosis, can it be treated? Clinico-experimental, prospective, sequential study]. ( Adrario, E; Caporelli, S; De Pace, F; Donati, A; Frezzotti, AR; Giovannini, C; Luzi, A; Munch, C; Pietropaoli, P, 1994) |
| " We suggest that these results reflect a model of grand mal seizure-induced lactic acidosis." | 5.06 | Effect of consecutive exercise bouts on plasma potassium concentration during exercise and recovery. ( Busse, MW; Maassen, N, 1989) |
| "We performed a systematic search on PubMed, applying the following search terms: "acute metabolic acidosis," "lactic acidosis," "metformin" AND "acidosis," "unbalanced solutions" AND "acidosis," "bicarbonate" AND "acidosis" AND "outcome," "acute metabolic acidosis" AND "management," and "acute metabolic acidosis" AND "renal replacement therapy (RRT)/dialysis." | 5.05 | Etiology and Management of Acute Metabolic Acidosis: An Update. ( Matyukhin, I; Patschan, D; Patschan, S; Ritter, O, 2020) |
| "L-lactic acidosis (L-LA) is the most common cause of metabolic acidosis in the critical care setting, which has been associated with a large increase in mortality." | 5.05 | L-lactic acidosis: pathophysiology, classification, and causes; emphasis on biochemical and metabolic basis. ( Halperin, ML; Kamel, KS; Oh, MS, 2020) |
| "Lactic acidosis in metformin use is a widely recognised but rare side effect." | 4.84 | Reality of severe metformin-induced lactic acidosis in the absence of chronic renal impairment. ( Bosch, FH; Bruijstens, LA; Buscher-Jungerhans, PM; van Luin, M, 2008) |
| "This article reviews the current body of knowledge regarding lactic acidosis in critically ill patients." | 4.78 | Lactic acidosis in critical illness. ( Falk, JL; Mizock, BA, 1992) |
| "Metformin-associated lactic acidosis (MALA) is a rare but life-threatening condition." | 4.12 | A patient with severe metformin-associated lactic acidosis complicated by acute coronary syndrome: a case report. ( Ahmed, A; Gudowski, C; Mammadova, N; Pliquett, RU; Shkodivskyi, P; Soukup, J, 2022) |
| "Metformin-associated lactic acidosis (MALA) carries a high mortality rate." | 3.96 | Metformin-associated lactic acidosis: reinforcing learning points. ( Creagh, F; Goonoo, MS; Morris, R; Raithatha, A, 2020) |
| "This study aims to determine whether there is a relationship between nausea level and lactic acidosis during recovery from sprinting." | 3.91 | Role of lactic acidosis as a mediator of sprint-mediated nausea. ( Chivers, PT; Cripps, AJ; Fournier, PA; Merrells, RJ, 2019) |
| "Metformin-associated lactic acidosis is a severe and infrequent adverse event." | 3.85 | [Metformin-associated lactic acidosis. Report of one case]. ( Dreyse, J; Orozco, R; Pezzani, MJ; Quintana, F; Regueira, T; Soto, L, 2017) |
| " Two cases of lactic acidosis due to ingestion of high dose metformin for suicidal purposes have been presented here; in both cases, clinical improvement was seen with bicarbonate hemodialysis." | 3.77 | Dialysis therapy for lactic acidosis caused by metformin intoxication: presentation of two cases. ( Aytemiz, E; Begenik, H; Emre, H; Erkoc, R; Ozturk, M; Soyoral, YU, 2011) |
| "Metformin-associated lactic acidosis is a rare and serious complication of biguanide treatment." | 3.75 | Metformin-associated lactic acidosis: a prognostic and therapeutic study. ( Fourrier, F; Houdret, N; Nseir, S; Seidowsky, A, 2009) |
| "Metformin-associated lactic acidosis is commonly accompanied with acute kidney injury." | 3.75 | Impact of acute kidney injury on metformin-associated lactic acidosis. ( Wen, YK, 2009) |
| " Forty-two percent of nonsurvivors had normal lactate levels, whereas 33% of survivors had lactic acidosis." | 3.74 | Comparison of acid-base models for prediction of hospital mortality after trauma. ( Kaplan, LJ; Kellum, JA, 2008) |
| " Extracellular pH defense against lactic acidosis was estimated from changes (Delta) in lactic acid ([La]), [HCO3-], pH and PCO2 in plasma, which equilibrates with interstitial fluid." | 3.74 | Extracellular pH defense against lactic acid in untrained and trained altitude residents. ( Böning, D; Coy, L; Mora, M; Reyes, O; Rojas, J; Serrato, M, 2008) |
| " The initial patient, and later her newborn sibling, had mildly dysmorphic features, lactic acidosis and a defect in mitochondrial respiratory complex II associated with many biochemical features of a block in fatty acid oxidation." | 3.72 | Respiratory complex II defect in siblings associated with a symptomatic secondary block in fatty acid oxidation. ( Bocian, M; Boyle, K; Gargus, JJ; Roe, CR; Roe, DS; Vianey-Saban, C, 2003) |
| " Although it seemed logical to administer sodium bicarbonate to attenuate acidemia and therefore lessen the impact on cardiac function, the routine use of bicarbonate in the treatment of the most common causes of severe acidemia, diabetic ketoacidosis, lactic acidosis, and cardiac arrest, has been an issue of great controversy." | 3.71 | Use of base in the treatment of severe acidemic states. ( Kraut, JA; Kurtz, I, 2001) |
| " Lactic acidosis occurred in 8 septic patients irrespective of the substitution fluid." | 3.69 | Comparison of a lactate-versus acetate-based hemofiltration replacement fluid in patients with acute renal failure. ( Grabensee, B; Heering, P; Heintzen, M; Manassa, E; Morgera, S; Passlick-Deetjen, J; Szentandrasi, T; Willers, R, 1997) |
| " Above the anaerobic threshold, accelerated glycolysis increases muscle lactic acidosis." | 3.69 | Determination of the anaerobic threshold by gas exchange: biochemical considerations, methodology and physiological effects. ( Casaburi, R; Cooper, CB; Koike, A; Stringer, WW; Wasserman, K, 1994) |
| "The effects of Carbicarb, sodium bicarbonate, and sodium chloride on arterial blood gases, lactate concentrations, hemodynamics, and myocardial intracellular pH were compared in hypoxic lactic acidosis with controlled carbon dioxide elimination." | 3.68 | Carbicarb, sodium bicarbonate, and sodium chloride in hypoxic lactic acidosis. Effect on arterial blood gases, lactate concentrations, hemodynamic variables, and myocardial intracellular pH. ( Levin, DL; McDonald, GG; Nunnally, RL; Rhee, KH; Toro, LO, 1993) |
| "During an incremental exercise test, three consequences of the onset of anaerobic metabolism can be observed: rise in blood lactate (lactate threshold, LT); fall in standard bicarbonate (lactic acidosis threshold, LAT); nonlinear increase in CO2 output (V-slope gas exchange threshold, GET)." | 3.68 | Comparison of gas exchange, lactate, and lactic acidosis thresholds in patients with chronic obstructive pulmonary disease. ( Appendini, L; Carone, M; Casaburi, R; Donner, CF; Patessio, A; Wasserman, K, 1993) |
| " Thus we investigated the effect of lactic acidosis and two proposed treatments on myocardial energetics and intracellular pH in anesthetized living rats." | 3.68 | Lactic acidosis: effect of treatment on intracellular pH and energetics in living rat heart. ( Barrett, E; Gore, JC; Greene, R; Majumdar, S; Zahler, R, 1992) |
| "Lactic acidosis decreases left ventricular contractility, but whether bicarbonate increases left ventricular contractility during lactic acidosis in vivo is controversial." | 3.68 | Bicarbonate does not increase left ventricular contractility during L-lactic acidemia in pigs. ( Cooper, DJ; Herbertson, MJ; Walley, KR; Werner, HA, 1993) |
| " The partial correction of lactic acidosis with oral sodium bicarbonate chronic therapy may result in a slow evolution of the clinical symptoms." | 3.68 | Congenital lactic acidosis due to a defect of pyruvate dehydrogenase complex (E1). Clinical, biochemical, nerve biopsy study and effect of therapy. ( Dotti, MT; Fabrizi, GM; Federico, A; Guazzi, GC; Malandrini, A; Massimo, L; Palmeri, S; Robinson, BH, 1990) |
| "The risk of D-lactic acidosis after consumption of yogurt was investigated in seven healthy volunteers." | 3.68 | Postprandial plasma D-lactate concentrations after yogurt ingestion. ( Barth, CA; de Vrese, M, 1991) |
| " We studied the effects of carbicarb in an animal preparation of hypoxic lactic acidosis (HLA)." | 3.67 | Improved hemodynamic function during hypoxia with Carbicarb, a new agent for the management of acidosis. ( Arieff, AI; Bersin, RM, 1988) |
| "Lactic acidosis in diabetics on metformin therapy is rare but still associated with poor prognosis." | 3.67 | Bicarbonate haemodialysis: an adequate treatment for lactic acidosis in diabetics treated by metformin. ( Coevoet, B; Debussche, X; Dkissi, H; Fournier, A; Lalau, JD; Quichaud, J; Temperville, B; Tolani, M; Westeel, PF, 1987) |
| "We studied the use of sodium bicarbonate administration in a canine model of hemorrhagic shock to determine its effect on hemodynamics, arterial and venous blood gases, respiratory gases, and blood lactate levels." | 3.67 | Effects of sodium bicarbonate in canine hemorrhagic shock. ( Benjamin, E; Gentili, DR; Iberti, TJ; Katz, DP; Kelly, KM; Premus, G; Rosen, M, 1988) |
| "The effects of iv sodium bicarbonate (NaHCO3) and Carbicarb, an experimental buffer, were compared in a rat model of lactic acidosis induced by controlled hemorrhage and asphyxia." | 3.67 | Brain pH effects of NaHCO3 and Carbicarb in lactic acidosis. ( Chan, L; Filley, GF; Kindig, NB; Kucera, RR; Shapiro, JI; Whalen, MA, 1989) |
| "Lactic acidosis is seen frequently after severe anoxia and circulatory failure." | 3.67 | Effect of dichloroacetate in the treatment of anoxic lactic acidosis in dogs. ( Caputo, G; Delgado Paredes, C; Egler, J; Fleisher, G; Schaible, D; Sheikh, A; Swedlow, D, 1986) |
| "We report two diabetic patients who developed lactic acidosis following the use of Buformin." | 3.67 | [Lactic acidosis in diabetic patients associated with buformin]. ( Díaz, RA; Hernández, G; Huidobro, F; Jimenez, R; Pérez, H; Torres, H; Videla, C, 1989) |
| "Critics of bicarbonate therapy for life-threatening lactic acidosis have argued that the treatment is not only ineffective but that it also worsens morbidity and mortality." | 3.67 | Bicarbonate therapy for organic acidosis: the case for its continued use. ( Cohen, JJ; Narins, RG, 1987) |
| "Surgery is the main treatment for liver cancer, but the most common liver cancer – called hepatocellular carcinoma – can sometimes become too large to remove safely." | 2.82 | A nonrandomized cohort and a randomized study of local control of large hepatocarcinoma by targeting intratumoral lactic acidosis. ( Chao, M; Hu, X; Jin, K; Li, B; Wu, H; Wu, J; Yang, G; Zhang, G, 2016) |
| "Lactic acidosis was more rapidly recovered and was significantly lower with bicarbonate solution for both shock and nonshock groups (3." | 2.70 | Better correction of metabolic acidosis, blood pressure control, and phagocytosis with bicarbonate compared to lactate solution in acute peritoneal dialysis. ( Lumlertgul, D; Supajatura, V; Thongboonkerd, V, 2001) |
| "Metabolic acidosis was readily controlled in all patients." | 2.68 | Continuous veno-venous hemodiafiltration using bicarbonate dialysate. ( Henning, PH; Hogg, RJ; Jureidini, KF; Matthews, N; Roy, D; Wilby, PA, 1997) |
| "In this model of cardiac arrest, carbicarb was not superior to sodium bicarbonate in the correction of metabolic acidosis during CPR." | 2.67 | Correction of metabolic acidosis in experimental CPR: a comparative study of sodium bicarbonate, carbicarb, and dextrose. ( Blecic, S; De Backer, D; Deleuze, M; Vachiery, JL; Vincent, JL, 1991) |
| " Similarly, no adverse changes occurred in systemic or pulmonary arterial pressures or in cardiac ejection fraction." | 2.67 | Safety of low-dose intraoperative bicarbonate therapy: a prospective, double-blind, randomized study. The Study of Perioperative Ischemia (SPI) Research Group. ( Arieff, AI; Leung, JM; Mangano, DT; Mark, NH, 1993) |
| "D-lactic acidosis is a rare complication that occurs mainly in patients with malabsorption due to a surgically altered gastrointestinal tract anatomy, namely in short bowel syndrome or after bariatric surgery." | 2.55 | D-lactic acidosis - case report and review of the literature. ( Fabian, E; Högenauer, C; Kramer, L; Krejs, GJ; Raggam, RB; Siebert, F; Wenzl, H, 2017) |
| "The exercise lactic acidosis has been observed to occur after the minimal capillary PO2 is reached." | 2.39 | Coupling of external to cellular respiration during exercise: the wisdom of the body revisited. ( Wasserman, K, 1994) |
| "The rare congenital lactic acidosis is a consequence of enzyme defects." | 2.38 | [Lactic acidosis]. ( Boner, G; Winkler, J, 1990) |
| "Uncomplicated metabolic acidosis is manifested by an increase in blood acidity, hypobicarbonatemia, and hypocapnea." | 2.38 | [Water-electrolyte and acid-base imbalance. VI. Metabolic acidosis]. ( Velásquez-Jones, L, 1990) |
| "Metabolic acidoses due to renal failure, bicarbonate losses, or lactic acidosis are common conditions, and the appropriate medical management of each is relevant to any inpatient medical provider." | 1.51 | The Treatment of Metabolic Acidosis: An Interactive Case-Based Learning Activity. ( Berkoben, M; Roberts, JK, 2019) |
| "Hypoxic lactic acidosis was efficiently reversed in group PR, instead of group CR, (pH 7." | 1.48 | Pyruvate in reduced osmolarity oral rehydration salt corrected lactic acidosis in sever scald rats. ( Li, ZY; Liu, R; Wang, SM; Yu, W; Zhang, HP; Zhou, FQ, 2018) |
| "Hypoxic lactic acidosis was fully corrected in group PORS in 4 h, whereas it worsened in group BORS, and the 24-h survival rate was twice higher in group PORS than in group BORS (45." | 1.42 | Pyruvate oral rehydration solution improved visceral function and survival in shock rats. ( He, ZJ; Hu, S; Lin, HY; Luo, HM; Sheng, ZY; Xie, ZY; Yu, W; Zhou, FQ, 2015) |
| "As the lactic acidosis was not in the setting of hypoxia or hemodynamic instability, we made the diagnosis of malignancy-associated type B lactic acidosis, also known as the Warburg's effect." | 1.40 | Warburg's effect on solid tumors. ( El Imad, T; El Khoury, L; Geara, AS, 2014) |
| "Neuromyelitis optica (NMO, Devic's syndrome) is a severely disabling disorder of the central nervous system characterized by optic neuritis and longitudinally extensive myelitis." | 1.39 | Aquaporin-4 antibodies, CNS acidosis and neuromyelitis optica: a potential link. ( Jarius, S; Wildemann, B, 2013) |
| "Her lactic acid concentration was 16." | 1.36 | A case of human poisoning with a flufenoxuron-containing insecticide. ( Cho, SJ; Han, SK; Jeong, J; Kim, J; Ryu, J; Yeom, S, 2010) |
| "Shock was more frequently present in the low [BE] group (46% versus 24%, P = 0." | 1.35 | Severe hyperlactatemia with normal base excess: a quantitative analysis using conventional and Stewart approaches. ( Dubin, A; Kutscherauer, DO; Masevicius, FD; Pein, MC; Tuhay, G, 2008) |
| "Metformin is an oral antidiabetic agent, widely used in the treatment of type 2 diabetes mellitus." | 1.35 | Serum bicarbonate: can it be a marker of metformin induced acidosis in geriatrics? ( Adhikari, P; Pai, MR; Pathak, R; Pemminati, S; Rajeshwari, S; Rathnakar, UP, 2009) |
| "D-lactic acidosis is a rare complication in children with short bowel syndrome." | 1.33 | Recurrent D-lactic acidosis in a child with short bowel syndrome. ( Mo-Suwan, L; Patrapinyokul, S; Puwanant, M, 2005) |
| "D-lactic acidosis was finally diagnosed by simultaneously determining D-lactate (8." | 1.29 | [Recurrent D-lactic acidosis with encephalopathy in a boy with short-bowel syndrome]. ( Koletzko, B; Koletzko, S; Waag, KL, 1994) |
| "The occurrence of hyperchloremia during diabetic ketoacidosis (DKA) recovery and the lack of correlation between anion gap excess (delta AG) and bicarbonate deficit (delta TCO2) on admission suggest an hyperchloremic acidosis (HCLA) component." | 1.28 | [Hyperchloremic acidosis in metabolic acidosis with anion gap excess. Comparison with diabetic ketoacidosis]. ( Bernardin, M; Brivet, F; Dormont, J, 1991) |
| "Lactic acidosis is a relatively frequent acid-base disorder in a hospital setting." | 1.28 | [Lactic acidosis and hyperlactatemia]. ( Perret, C; Potin, M, 1990) |
| "Two patients with lactic acidosis are described, along with our experience using CAVHD and citrate in other clinical settings." | 1.28 | Lactic acidosis treated with continuous hemodiafiltration and regional citrate anticoagulation. ( Galishoff, M; Kirschbaum, B; Reines, HD, 1992) |
| "Serum lactic acidosis is characterized by a pH less than 7." | 1.27 | Comparison of sodium bicarbonate with dichloroacetate treatment of hyperlactatemia and lactic acidosis in the ischemic rat. ( Biros, MH; Dimlich, RV; Kaplan, J; Widman, DW, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (19.59) | 18.7374 |
| 1990's | 61 (41.22) | 18.2507 |
| 2000's | 28 (18.92) | 29.6817 |
| 2010's | 22 (14.86) | 24.3611 |
| 2020's | 8 (5.41) | 2.80 |
| Authors | Studies |
|---|---|
| Mones, AB | 1 |
| Gruber, EJ | 1 |
| Harms, CA | 1 |
| Lohmann, CMF | 1 |
| Lohmann, KJ | 1 |
| Lewbart, GA | 1 |
| Mammadova, N | 1 |
| Soukup, J | 1 |
| Shkodivskyi, P | 1 |
| Gudowski, C | 1 |
| Ahmed, A | 1 |
| Pliquett, RU | 1 |
| Ying, C | 1 |
| Jin, C | 1 |
| Zeng, S | 1 |
| Chao, M | 2 |
| Hu, X | 2 |
| Wardi, G | 1 |
| Holgren, S | 1 |
| Gupta, A | 1 |
| Sobel, J | 1 |
| Birch, A | 1 |
| Pearce, A | 1 |
| Malhotra, A | 1 |
| Tainter, C | 1 |
| Tanemoto, M | 1 |
| Yamada, S | 1 |
| Kimura, T | 1 |
| Yokoyama, T | 1 |
| Okazaki, Y | 1 |
| Masy, V | 1 |
| Sokal, E | 1 |
| Ranguelov, N | 1 |
| Brichard, B | 1 |
| Laterre, PF | 1 |
| Hantson, P | 1 |
| Santos, MM | 1 |
| Bregadioli, GC | 1 |
| Santos, LGC | 1 |
| Curti, JM | 1 |
| Duarte, CABG | 1 |
| Cerri, FM | 1 |
| Pereira, PFV | 1 |
| Flaiban, KKMC | 1 |
| Filho, JDR | 1 |
| Lisbôa, JAN | 1 |
| Merrells, RJ | 1 |
| Cripps, AJ | 1 |
| Chivers, PT | 1 |
| Fournier, PA | 1 |
| Kamel, KS | 2 |
| Oh, MS | 1 |
| Halperin, ML | 2 |
| Berkoben, M | 1 |
| Roberts, JK | 1 |
| Matyukhin, I | 1 |
| Patschan, S | 1 |
| Ritter, O | 1 |
| Patschan, D | 1 |
| Goonoo, MS | 1 |
| Morris, R | 1 |
| Raithatha, A | 1 |
| Creagh, F | 1 |
| Quintana, F | 1 |
| Pezzani, MJ | 1 |
| Orozco, R | 1 |
| Dreyse, J | 1 |
| Soto, L | 1 |
| Regueira, T | 1 |
| Liu, R | 1 |
| Wang, SM | 1 |
| Li, ZY | 1 |
| Yu, W | 2 |
| Zhang, HP | 1 |
| Zhou, FQ | 3 |
| Wang, Y | 1 |
| Huang, Y | 1 |
| Yang, J | 1 |
| Zhao, L | 1 |
| Zhou, H | 1 |
| Nadler, ST | 1 |
| Suri, J | 1 |
| Swenson, ER | 1 |
| Jarius, S | 1 |
| Wildemann, B | 1 |
| Tébar, MT | 1 |
| de Luis, N | 1 |
| Sánchez, I | 1 |
| Aguilera, L | 1 |
| Zagatto, AM | 1 |
| Padulo, J | 1 |
| Müller, PT | 1 |
| Miyagi, WE | 1 |
| Malta, ES | 1 |
| Papoti, M | 1 |
| Hu, S | 1 |
| Xie, ZY | 1 |
| He, ZJ | 1 |
| Luo, HM | 1 |
| Lin, HY | 1 |
| Sheng, ZY | 1 |
| El Imad, T | 1 |
| El Khoury, L | 1 |
| Geara, AS | 1 |
| Aronovich, D | 1 |
| Trotter, M | 1 |
| Rivera, C | 1 |
| Dalley, M | 1 |
| Farcy, D | 1 |
| Betancourt, M | 1 |
| Howard, L | 1 |
| Licciardi, S | 1 |
| Cubeddu, L | 1 |
| Goldszer, R | 1 |
| Wu, H | 1 |
| Jin, K | 1 |
| Li, B | 1 |
| Wu, J | 1 |
| Zhang, G | 1 |
| Yang, G | 1 |
| Fabian, E | 1 |
| Kramer, L | 1 |
| Siebert, F | 1 |
| Högenauer, C | 1 |
| Raggam, RB | 1 |
| Wenzl, H | 1 |
| Krejs, GJ | 1 |
| Benatti, M | 1 |
| Pazin-Filho, A | 1 |
| Miranda, CH | 1 |
| Jones, N | 1 |
| Beneke, R | 1 |
| Wen, YK | 1 |
| Seidowsky, A | 1 |
| Nseir, S | 1 |
| Houdret, N | 1 |
| Fourrier, F | 1 |
| Lheureux, PE | 1 |
| Lheureux, OF | 1 |
| Penaloza-Baeza, A | 1 |
| Jeong, J | 1 |
| Yeom, S | 1 |
| Ryu, J | 1 |
| Han, SK | 1 |
| Cho, SJ | 1 |
| Kim, J | 1 |
| Liamis, G | 1 |
| Milionis, HJ | 1 |
| Elisaf, M | 1 |
| Rosival, V | 1 |
| Rajeshwari, S | 1 |
| Adhikari, P | 1 |
| Pai, MR | 1 |
| Pemminati, S | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Metformin Overdose in Adult Patients Treated at the University Hospital of Nancy: Single-center Descriptive Retrospective Observational Study[NCT04762966] | 50 participants (Anticipated) | Observational | 2021-03-01 | Recruiting | |||
| A Randomized Controlled Trial of the Efficacy of Hepatectomy or TILA-TACE in Patients With Resectable Hepatocellular Carcinoma[NCT03314532] | 230 participants (Anticipated) | Interventional | 2017-11-01 | Not yet recruiting | |||
| Strong Ion Gap as Prognostic Indicator for Adult Patients Admitted With Shock to the Intensive Care Units[NCT02652364] | 112 participants (Actual) | Observational | 2015-10-31 | Completed | |||
| Pharmacotoxicology of Trichloroethylene Metabolites: Short-term Effect of DCA on in Vivo Tyrosine Catabolism and MAAI Expression[NCT00865514] | 2 participants (Actual) | Interventional | 2011-08-31 | Terminated (stopped due to Difficulty in obtaining the solution from the compounding pharmacies caused a two year delay in start-up; the funding ended prior to study completion.) | |||
| Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill : A Multiple Center Randomized Clinical Trial (BICAR-ICU)[NCT02476253] | Phase 3 | 400 participants (Anticipated) | Interventional | 2015-05-05 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
23 reviews available for hydrogen carbonate and Lactic Acidosis
| Article | Year |
|---|---|
A Review of Bicarbonate Use in Common Clinical Scenarios.
Topics: Acidosis; Acidosis, Lactic; Bicarbonates; Child; Heart Arrest; Humans; Sodium Bicarbonate | 2023 |
L-lactic acidosis: pathophysiology, classification, and causes; emphasis on biochemical and metabolic basis.
Topics: Acidosis, Lactic; Anions; Bicarbonates; Citric Acid Cycle; Critical Illness; Electron Transport Chai | 2020 |
Etiology and Management of Acute Metabolic Acidosis: An Update.
Topics: Acidosis; Acidosis, Lactic; Acute Disease; Animals; Bicarbonates; Disease Management; Electrolytes; | 2020 |
Pyruvate is a prospective alkalizer to correct hypoxic lactic acidosis.
Topics: Acidosis, Lactic; Antacids; Bicarbonates; Erythropoietin; Fluid Therapy; Humans; Hypoxia; Hypoxia-In | 2018 |
D-lactic acidosis - case report and review of the literature.
Topics: Acidosis, Lactic; Anti-Bacterial Agents; Bicarbonates; Combined Modality Therapy; Diet Therapy; Fema | 2017 |
Pharmacologically-induced metabolic acidosis: a review.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Lactic; Acidosis, Renal Tubular; Bicarbonates; Diabetic K | 2010 |
[Metabolic acidosis from... metabolic origin].
Topics: Acidosis; Acidosis, Lactic; Bicarbonates; Child; Child, Preschool; Humans; Infant; Infant, Newborn; | 2010 |
Severe metabolic complications from theophylline intoxication.
Topics: Acidosis, Lactic; Aged, 80 and over; Bicarbonates; Carbon Dioxide; Humans; Hypokalemia; Ketosis; Mal | 2003 |
Reality of severe metformin-induced lactic acidosis in the absence of chronic renal impairment.
Topics: Acidosis, Lactic; Aged; Bicarbonates; Female; Humans; Hypoglycemic Agents; Kidney Failure, Chronic; | 2008 |
Gastric intramucosal pH, tissue oxygenation and acid-base balance.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Adenosine Triphosphate; Bicarbonates; Gastric Mucosa; Human | 1995 |
Coupling of external to cellular respiration during exercise: the wisdom of the body revisited.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Buffers; Capillaries; Carbon Dioxide; Humans; Lactates; Lac | 1994 |
[Should bicarbonates still be administered in lactic acidosis?].
Topics: Acidosis, Lactic; Bicarbonates; Carbon Dioxide; Carbonates; Dichloroacetic Acid; Drug Combinations; | 1993 |
The use of sodium bicarbonate in neonatal resuscitation: help or harm?
Topics: Acidosis, Lactic; Bicarbonates; Clinical Protocols; Evaluation Studies as Topic; Heart Arrest; Human | 1993 |
Methanol intoxication. How to help patients who have been exposed to toxic solvents.
Topics: Acidosis, Lactic; Bicarbonates; Ethanol; Humans; Metabolic Clearance Rate; Methanol; Poisoning; Prog | 1993 |
Buffers: bicarbonate, lactate and pyruvate.
Topics: Acidosis, Lactic; Bicarbonates; Buffers; Dialysis Solutions; Humans; Lactic Acid; Peritoneal Dialysi | 1996 |
Lactic acidosis in critical illness.
Topics: Acidosis, Lactic; Bicarbonates; Blood Gas Analysis; Carbonates; Citric Acid Cycle; Critical Illness; | 1992 |
[Therapy of metabolic acidosis].
Topics: Acidosis; Acidosis, Lactic; Alkalies; Animals; Bicarbonates; Carbonates; Diabetic Ketoacidosis; Dich | 1991 |
Acid-base changes during complete brain ischemia.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Lactic; Adenosine Triphosphate; Bicarbonates; Brain Ische | 1990 |
Sodium bicarbonate in the treatment of subtypes of acute lactic acidosis: physiologic considerations.
Topics: Acidosis, Lactic; Acute Disease; Animals; Bicarbonates; Carbon Dioxide; Cardiac Output, Low; Humans; | 1990 |
[Management and treatment of lactic acidosis].
Topics: Acidosis, Lactic; Bicarbonates; Diabetes Complications; Diabetes Mellitus; Humans; Metformin; Renal | 1990 |
[Lactic acidosis].
Topics: Acidosis, Lactic; Alkalosis; Bicarbonates; Dose-Response Relationship, Drug; Humans; Insulin; Nitrop | 1990 |
[Water-electrolyte and acid-base imbalance. VI. Metabolic acidosis].
Topics: Acid-Base Imbalance; Acidosis; Acidosis, Lactic; Bicarbonates; Chlorides; Extracellular Space; Human | 1990 |
The danger of high dose sodium bicarbonate in biguanide-induced lactic acidosis: the theory, the practice and alternative therapies.
Topics: Acidosis, Lactic; Bicarbonates; Biguanides; Humans; Sodium; Sodium Bicarbonate | 1987 |
11 trials available for hydrogen carbonate and Lactic Acidosis
| Article | Year |
|---|---|
A nonrandomized cohort and a randomized study of local control of large hepatocarcinoma by targeting intratumoral lactic acidosis.
Topics: Acidosis, Lactic; Adult; Aged; Aged, 80 and over; Bicarbonates; Carcinoma; Chemoembolization, Therap | 2016 |
[Intraoperative lactic acidosis, can it be treated? Clinico-experimental, prospective, sequential study].
Topics: Acidosis, Lactic; Bicarbonates; Carnitine; Humans; Intraoperative Complications; Prospective Studies | 1994 |
Safety of low-dose intraoperative bicarbonate therapy: a prospective, double-blind, randomized study. The Study of Perioperative Ischemia (SPI) Research Group.
Topics: Acidosis, Lactic; Aged; Bicarbonates; Blood Gas Analysis; Blood Glucose; Calcium; Cardiac Output; Co | 1993 |
Hemodynamic effects of sodium bicarbonate in critically ill neonates.
Topics: Acidosis, Lactic; Bicarbonates; Birth Weight; Blood Gas Analysis; Blood Gas Monitoring, Transcutaneo | 1993 |
Continuous veno-venous hemodiafiltration using bicarbonate dialysate.
Topics: Acidosis; Acidosis, Lactic; Acute Kidney Injury; Adolescent; Bicarbonates; Child; Child, Preschool; | 1997 |
Better correction of metabolic acidosis, blood pressure control, and phagocytosis with bicarbonate compared to lactate solution in acute peritoneal dialysis.
Topics: Acidosis, Lactic; Acute Kidney Injury; Adult; Bicarbonates; Blood Pressure; Dialysis Solutions; Fema | 2001 |
Lactate or bicarbonate for intermittent hemofiltration?
Topics: Acidosis, Lactic; Acute Kidney Injury; Bicarbonates; Buffers; Female; Hemodialysis Solutions; Hemofi | 1991 |
Correction of metabolic acidosis in experimental CPR: a comparative study of sodium bicarbonate, carbicarb, and dextrose.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Blood Gas Analysis; Carbonates; Clinical Protocols; Disease | 1991 |
Effects of bicarbonate therapy on hemodynamics and tissue oxygenation in patients with lactic acidosis: a prospective, controlled clinical study.
Topics: Acidosis, Lactic; Aged; Bicarbonates; Critical Care; Female; Hemodynamics; Humans; Male; Middle Aged | 1991 |
Bicarbonate does not improve hemodynamics in critically ill patients who have lactic acidosis. A prospective, controlled clinical study.
Topics: Acidosis, Lactic; Adult; Aged; Aged, 80 and over; Bicarbonates; Calcium; Carbon Dioxide; Data Interp | 1990 |
Effect of consecutive exercise bouts on plasma potassium concentration during exercise and recovery.
Topics: Acidosis, Lactic; Adolescent; Adult; Bicarbonates; Clinical Trials as Topic; Exercise; Humans; Hydro | 1989 |
114 other studies available for hydrogen carbonate and Lactic Acidosis
| Article | Year |
|---|---|
LACTIC ACIDOSIS INDUCED BY MANUAL RESTRAINT FOR HEALTH EVALUATION AND COMPARISON OF TWO POINT-OF-CARE ANALYZERS IN HEALTHY LOGGERHEAD SEA TURTLES (
Topics: Acidosis, Lactic; Animals; Bicarbonates; Carbon Dioxide; Point-of-Care Systems; Turtles | 2021 |
A patient with severe metformin-associated lactic acidosis complicated by acute coronary syndrome: a case report.
Topics: Acidosis, Lactic; Acute Coronary Syndrome; Acute Kidney Injury; Bicarbonates; Diabetes Mellitus, Typ | 2022 |
Alkalization of cellular pH leads to cancer cell death by disrupting autophagy and mitochondrial function.
Topics: Acidosis, Lactic; Autophagy; Bicarbonates; Carcinoma, Hepatocellular; Cell Death; Chemoembolization, | 2022 |
Misdiagnosis of high anion gap acidosis owing to instrument error of a device.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Lactic; Aged; Albumins; Bicarbonates; Blood Chemical Anal | 2019 |
Fatal type B lactic acidosis in a patient with end-stage liver disease related to homozygous sickle cell disease.
Topics: Acidosis, Lactic; Adolescent; Anemia, Sickle Cell; Bicarbonates; Catheter-Related Infections; End St | 2019 |
Treatment of acute rumen lactic acidosis with intravenous hypertonic sodium chloride or bicarbonate solutions followed by intraruminal water.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Female; Infusions, Intravenous; Random Allocation; Rumen; S | 2020 |
Role of lactic acidosis as a mediator of sprint-mediated nausea.
Topics: Acidosis, Lactic; Adult; Bicarbonates; Carbon Dioxide; Humans; Hydrogen-Ion Concentration; Lactic Ac | 2019 |
The Treatment of Metabolic Acidosis: An Interactive Case-Based Learning Activity.
Topics: Acid-Base Imbalance; Acidosis; Acidosis, Lactic; Bicarbonates; Critical Care; Education, Medical, Un | 2019 |
Metformin-associated lactic acidosis: reinforcing learning points.
Topics: Acidosis, Lactic; Acute Kidney Injury; Bicarbonates; Continuous Renal Replacement Therapy; Diabetes | 2020 |
[Metformin-associated lactic acidosis. Report of one case].
Topics: Acidosis, Lactic; Bicarbonates; Diabetes Mellitus, Type 2; Female; Hemofiltration; Humans; Hypoglyce | 2017 |
Pyruvate in reduced osmolarity oral rehydration salt corrected lactic acidosis in sever scald rats.
Topics: Acidosis, Lactic; Administration, Oral; Animals; Bicarbonates; Burns; Citric Acid; Disease Models, A | 2018 |
How Basic Can You Be?
Topics: Acidosis, Lactic; Alkalosis; Alkalosis, Respiratory; Bicarbonates; Diagnosis, Differential; Humans; | 2019 |
Aquaporin-4 antibodies, CNS acidosis and neuromyelitis optica: a potential link.
Topics: Acidosis, Lactic; Animals; Aquaporin 4; Astrocytes; Autoantibodies; Bicarbonates; Humans; Hydrogen-I | 2013 |
[Metformin-associated lactic acidosis in the Intensive Care Unit].
Topics: Acidosis, Lactic; Aged; Aged, 80 and over; Bicarbonates; Combined Modality Therapy; Diabetes Mellitu | 2014 |
Hyperlactemia induction modes affect the lactate minimum power and physiological responses in cycling.
Topics: Acidosis, Lactic; Adult; Bicarbonates; Bicycling; Exercise Test; Humans; Hydrogen-Ion Concentration; | 2014 |
Pyruvate oral rehydration solution improved visceral function and survival in shock rats.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Disease Models, Animal; Fluid Therapy; Glucose; Lipid Perox | 2015 |
Warburg's effect on solid tumors.
Topics: Acidosis, Lactic; Acute Kidney Injury; Administration, Intravenous; Aged; Bicarbonates; Disease Prog | 2014 |
Is serum lactate necessary in patients with normal anion gap and serum bicarbonate?
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis, Lactic; Aged; Bicarbonates; Cell Hypoxia; Evid | 2015 |
Reversal of refractory severe lactic acidosis by thiamine replacement.
Topics: Acidosis, Lactic; Acute Disease; Administration, Intravenous; Adult; Aged; Alcoholism; Anti-Bacteria | 2017 |
Another "great trans-Atlantic acid-base debate" (1)?
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Animals; Bicarbonates; Humans; Hydrogen; Hypercapnia; Muscl | 2008 |
Still no convincing evidence to call out the post lactic acidosis era.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Buffers; Exercise; Glycolysis; Humans; Hydrogen-Ion Concent | 2008 |
Impact of acute kidney injury on metformin-associated lactic acidosis.
Topics: Academic Medical Centers; Acidosis, Lactic; Acute Kidney Injury; Aged; Anti-Bacterial Agents; Bicarb | 2009 |
Metformin-associated lactic acidosis: a prognostic and therapeutic study.
Topics: Acidosis, Lactic; Adolescent; Adult; Aged; Aged, 80 and over; Bicarbonates; Buffers; Cohort Studies; | 2009 |
Metformin toxicity.
Topics: Acidosis, Lactic; Bicarbonates; Humans; Hypoglycemic Agents; Metformin; Plasmapheresis; Renal Dialys | 2009 |
A case of human poisoning with a flufenoxuron-containing insecticide.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Aged; Bicarbonates; Cardiac Output; Female; Humans; Insecti | 2010 |
[Rapid blood pH recovery in comatose patients with lactic acidosis is life saving].
Topics: Acidosis, Lactic; Bicarbonates; Coma; Combined Modality Therapy; Female; Humans; Hydrogen-Ion Concen | 2010 |
Serum bicarbonate: can it be a marker of metformin induced acidosis in geriatrics?
Topics: Acidosis, Lactic; Aged; Bicarbonates; Biomarkers; Creatinine; Female; Humans; Hypoglycemic Agents; M | 2009 |
Dialysis therapy for lactic acidosis caused by metformin intoxication: presentation of two cases.
Topics: Acidosis, Lactic; Adolescent; Bicarbonates; Diabetes Mellitus, Type 2; Dialysis Solutions; Humans; H | 2011 |
Reversible nucleoside analogue-associated lactic acidosis despite a prolonged course.
Topics: Acidosis, Lactic; Adult; Anti-HIV Agents; Bicarbonates; Female; Hemodiafiltration; HIV Reverse Trans | 2003 |
Unmeasured anions in critically ill patients: can they predict mortality?
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Aged; APACHE; Bicarbonates; Blood Gas Analysis; Calcium; Ca | 2003 |
SPONTANEOUS LACTIC ACIDOSIS. THE NATURE OF THE ACID-BASE DISTURBANCE AND CONSIDERATIONS IN DIAGNOSIS AND MANAGEMENT.
Topics: Acidosis; Acidosis, Lactic; Bicarbonates; Blood Chemical Analysis; Diagnosis, Differential; Disease | 1963 |
[LACTIC ACIDOSIS].
Topics: Acidosis; Acidosis, Lactic; Bicarbonates; Classification; Clinical Laboratory Techniques; Drug Thera | 1965 |
FAMILIAL INFANTILE LACTIC ACIDOSIS.
Topics: Acidosis; Acidosis, Lactic; Bicarbonates; Blood Chemical Analysis; Blood Glucose; Clinical Enzyme Te | 1965 |
Respiratory complex II defect in siblings associated with a symptomatic secondary block in fatty acid oxidation.
Topics: Acidosis, Lactic; Acyl-CoA Dehydrogenase; Behavior; Bicarbonates; Carnitine; Cell Line; Fatty Acids; | 2003 |
Fatal lactic acidosis associated with highly active antiretroviral therapy in patients with advanced human immunodeficiency virus infection in Taiwan.
Topics: Acid-Base Imbalance; Acidosis, Lactic; Adult; Aged; Alanine Transaminase; Antiretroviral Therapy, Hi | 2004 |
Effect of graded hypoxic and acidotic stress on contractile force of heart muscle from hypoxia-tolerant and hypoxia-intolerant turtles.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Hydrogen-Ion Concentration; Myocardial Contraction; Oxygen; | 2005 |
Recurrent D-lactic acidosis in a child with short bowel syndrome.
Topics: Acidosis, Lactic; Adolescent; Bicarbonates; Dietary Carbohydrates; Humans; Male; Parenteral Nutritio | 2005 |
Hyperlactataemia induced by CVVHDF with low lactate bicarbonate-buffered solutions in patients with liver dysfunction.
Topics: Acidosis, Lactic; Acute Kidney Injury; Bicarbonates; Female; Hemodiafiltration; Humans; Lactates; Li | 2006 |
Investigations on the association of D-lactate blood concentrations with the outcome of therapy of acidosis, and with posture and demeanour in young calves with diarrhoea.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Animals; Animals, Newborn; Bicarbonates; Cattle; Cattle Dis | 2006 |
Sustained low-efficiency dialysis as a treatment modality in a patient with lymphoma-associated lactic acidosis.
Topics: Acidosis, Lactic; Aged; Bicarbonates; Dialysis; Humans; Hydrogen-Ion Concentration; Lactates; Lactic | 2007 |
When a friend can become an enemy! Recognition and management of metformin-associated lactic acidosis.
Topics: Acidosis, Lactic; Aged; Bicarbonates; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents | 2007 |
Comparison of acid-base models for prediction of hospital mortality after trauma.
Topics: Acidosis, Lactic; Adult; Bicarbonates; Biomarkers; Female; Hospital Mortality; Humans; Hydrogen-Ion | 2008 |
Extracellular pH defense against lactic acid in untrained and trained altitude residents.
Topics: Acclimatization; Acid-Base Equilibrium; Acidosis, Lactic; Adaptation, Physiological; Adult; Altitude | 2008 |
Severe hyperlactatemia with normal base excess: a quantitative analysis using conventional and Stewart approaches.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Aged; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Chl | 2008 |
[Idiopathic lactic acidosis in a patient with AIDS].
Topics: Acidosis, Lactic; Acquired Immunodeficiency Syndrome; Adult; Bicarbonates; Female; Humans; Infusions | 1995 |
[Compensating for acidosis: contra].
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Lactic; Bicarbonates; Buffers; Cardiopulmonary Resuscitat | 1994 |
Comparative effects of bicarbonate, tris-(hydroxymethyl)aminomethane and dichloroacetate in newborn swine with normoxic lactic acidosis.
Topics: Acidosis, Lactic; Alkalies; Animals; Animals, Newborn; Bicarbonates; Cardiovascular System; Dichloro | 1993 |
Determination of the anaerobic threshold by gas exchange: biochemical considerations, methodology and physiological effects.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Adult; Anaerobic Threshold; Bicarbonates; Carbon Dioxide; E | 1994 |
Bicarbonate does not increase left ventricular contractility during L-lactic acidemia in pigs.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Heart Ventricles; Hydrogen-Ion Concentration; Lactates; Lac | 1994 |
[Recurrent D-lactic acidosis with encephalopathy in a boy with short-bowel syndrome].
Topics: Acidosis, Lactic; Bicarbonates; Brain Diseases, Metabolic; Child; Dietary Carbohydrates; Humans; Mal | 1994 |
Hyperchloremic acidosis during grand mal seizure lactic acidosis.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Acute Disease; Bicarbonates; Blood Gas Analysis; Chlorides; | 1994 |
The use of dichloroacetate in the treatment of overwhelming hypoxic acidosis.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Blood Pressure; Cardiac Output; Cause of Death; Coronary Ci | 1994 |
Bicarbonate does not increase left ventricular contractility during L-lactic acidemia in pigs.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Blood Pressure; Carbon Dioxide; Cardiac Output; Cardiac Pac | 1993 |
Comparison of gas exchange, lactate, and lactic acidosis thresholds in patients with chronic obstructive pulmonary disease.
Topics: Acidosis, Lactic; Anaerobic Threshold; Bicarbonates; Carbon Dioxide; Exercise Test; Humans; Lactates | 1993 |
Some logistical aspects of the treatment of lactic acidosis in two calves.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Cattle; Cattle Diseases; Infusions, Intravenous; Male; Sodi | 1993 |
Bicarbonate and haemodynamics in neonates.
Topics: Acidosis, Lactic; Bicarbonates; Hemodynamics; Humans; Infant, Newborn; Research Design; Sodium; Sodi | 1993 |
Carbicarb, sodium bicarbonate, and sodium chloride in hypoxic lactic acidosis. Effect on arterial blood gases, lactate concentrations, hemodynamic variables, and myocardial intracellular pH.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Carbon Dioxide; Carbonates; Dogs; Drug Combinations; Hemody | 1993 |
Lactic acidosis associated with propofol.
Topics: Acidosis, Lactic; Adult; Anti-Asthmatic Agents; Asthma; Bicarbonates; Female; Humans; Hypnotics and | 1996 |
Modelling of acid-base equilibria.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Acidosis, Lactic; Algorithms; Alkalosis; Anion | 1995 |
Anion gap: may the anions restricted to the intravascular space undergo modification in their valence?
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Animals; Anions; Bicarbonates; Blood Proteins; Extracellula | 1996 |
Comparison of a lactate-versus acetate-based hemofiltration replacement fluid in patients with acute renal failure.
Topics: Acetates; Acid-Base Equilibrium; Acidosis, Lactic; Acute Kidney Injury; APACHE; Bicarbonates; Blood | 1997 |
Bicarbonate haemodialysis as a treatment of metformin overdose.
Topics: Acidosis, Lactic; Adult; Bicarbonates; Buffers; Drug Overdose; Humans; Hypoglycemic Agents; Lactic A | 1997 |
Clinical impact of peritoneal equilibration testing in treatment of congenital lactic acidosis by acute peritoneal dialysis.
Topics: Acidosis, Lactic; Bicarbonates; Body Weight; Dialysis Solutions; Fatal Outcome; Humans; Hydrogen-Ion | 1997 |
Fixed acid uptake by visceral organs during early endotoxemia.
Topics: Acidosis; Acidosis, Lactic; Acids; Animals; Bicarbonates; Biological Transport, Active; Body Fluids; | 1997 |
[Insufficient correction of blood bicarbonate levels in biguanide lactic acidosis treated with CVVH and bicarbonate replacement fluids].
Topics: Acidosis, Lactic; Acute Kidney Injury; Aged; Bicarbonates; Buffers; Diabetes Mellitus, Type 2; Drug | 1997 |
[The influence of correction of acidosis on plasma level of branched-chain amino acids in chronic hemodialysis patients].
Topics: Acidosis, Lactic; Adult; Amino Acids, Branched-Chain; Bicarbonates; Female; Hemodiafiltration; Human | 1998 |
Bicarbonate-based haemofiltration in the management of acute renal failure with lactic acidosis.
Topics: Acidosis, Lactic; Acute Kidney Injury; Bicarbonates; Hemofiltration; Humans; Middle Aged; Retrospect | 1998 |
Treatment of combined renal failure and lactic acidosis by haemofiltration.
Topics: Acidosis, Lactic; Acute Kidney Injury; Adolescent; Adult; Aged; Bicarbonates; Child; Evaluation Stud | 1992 |
Unmeasured anions identified by the Fencl-Stewart method predict mortality better than base excess, anion gap, and lactate in patients in the pediatric intensive care unit.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Chlorides | 1999 |
[D-lactic acidosis in short bowel syndrome].
Topics: Acidosis, Lactic; Bicarbonates; Child, Preschool; Female; Humans; Infant; Isomerism; Lactates; Male; | 1999 |
Mechanisms of endothelial cell swelling from lactacidosis studied in vitro.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis, Lactic; Amiloride; Animals; Bicarbonates | 2000 |
Use of base in the treatment of severe acidemic states.
Topics: Acidosis; Acidosis, Lactic; Animals; Arrhythmias, Cardiac; Bicarbonates; Buffers; Calcium; Carbonate | 2001 |
Renal manifestations of congenital lactic acidosis.
Topics: Acidosis, Lactic; Adolescent; Adult; Bicarbonates; Blood Urea Nitrogen; Calcium; Child; Child, Presc | 2002 |
A slice of bread.
Topics: Acidosis, Lactic; Alcoholism; Bicarbonates; Fatal Outcome; Fluid Therapy; Food; Humans; Internship a | 2002 |
[BE and lactate--old parameters in a new light].
Topics: Acidosis, Lactic; Bicarbonates; Blood Gas Analysis; Humans; Hydrogen-Ion Concentration; Water-Electr | 2002 |
[Recurrent episodes of acidosis with encephalopathy in a hemodialysis program patient with short bowel syndrome].
Topics: Acidosis, Lactic; Adult; Bicarbonates; Brain Diseases, Metabolic; Consciousness Disorders; Drug Ther | 2002 |
Lactic acidosis treated with continuous hemodiafiltration and regional citrate anticoagulation.
Topics: Acidosis, Lactic; Adult; Aged; Bicarbonates; Chlorides; Citrates; Citric Acid; Female; Hemofiltratio | 1992 |
Treating acidosis in fulminant hepatic failure: the case against use of bicarbonate solutions.
Topics: Acidosis, Lactic; Bicarbonates; Humans; Liver Diseases; Sodium; Sodium Bicarbonate | 1992 |
Lactic acidosis: effect of treatment on intracellular pH and energetics in living rat heart.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Energy Metabolism; Hemodynamics; Hydrogen; Hydrogen-Ion Con | 1992 |
Lactic acidosis in malignant lymphoma.
Topics: Acidosis, Lactic; Adult; Aged; Bicarbonates; Female; Humans; Hydrogen-Ion Concentration; Lymphoma, T | 1991 |
Severe lactic acidosis following theophylline overdose.
Topics: Acidosis, Lactic; Adult; Bicarbonates; Charcoal; Coma; Drug Overdose; Emergencies; Female; Glasgow C | 1991 |
[Hyperchloremic acidosis in metabolic acidosis with anion gap excess. Comparison with diabetic ketoacidosis].
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Bicarbonates; Chlorides; Diabetic Ketoacidosis; Humans; Pre | 1991 |
[Lactic acidosis inpatients with diabetes mellitus].
Topics: Acidosis, Lactic; Adolescent; Adult; Aged; Bicarbonates; Blood Glucose; Diabetic Ketoacidosis; Dichl | 1991 |
Successful treatment of severe lactic acidosis by haemofiltration using a bicarbonate-based replacement fluid.
Topics: Acidosis, Lactic; Adult; Bicarbonates; Female; Hemofiltration; Humans; Immunosuppressive Agents; Kid | 1991 |
Postprandial plasma D-lactate concentrations after yogurt ingestion.
Topics: Acidosis, Lactic; Adult; Bicarbonates; Female; Humans; Hydrogen-Ion Concentration; Lactates; Lactic | 1991 |
Comparative effects of bicarbonate and dichloroacetate in newborn swine with hypoxic lactic acidosis.
Topics: Acidosis, Lactic; Animals; Animals, Newborn; Bicarbonates; Blood Pressure; Cardiac Output; Dichloroa | 1990 |
Congenital lactic acidosis due to a defect of pyruvate dehydrogenase complex (E1). Clinical, biochemical, nerve biopsy study and effect of therapy.
Topics: Acidosis, Lactic; Bicarbonates; Biopsy; Brain Diseases, Metabolic; Child; Fibroblasts; Humans; Leigh | 1990 |
Lactic acidosis.
Topics: Acidosis, Lactic; Bicarbonates; Critical Care; Humans; Sodium; Sodium Bicarbonate | 1990 |
[Lactic acidosis and hyperlactatemia].
Topics: Acidosis, Lactic; Bicarbonates; Dichloroacetic Acid; Humans; Lactates | 1990 |
Severe metabolic acidosis and "muti" (traditional herbal medicine) ingestion in young children.
Topics: Acidosis, Lactic; Bicarbonates; Electrolytes; Female; Fluid Therapy; Humans; Hydrogen-Ion Concentrat | 1990 |
Enhancement of iron-catalyzed free radical formation by acidosis in brain homogenates: differences in effect by lactic acid and CO2.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Brain; Carbon Dioxide; Free Radicals; Iron; Lipid Peroxides | 1989 |
Face-mask CPAP and sodium bicarbonate infusion in acute, severe asthma and metabolic acidosis.
Topics: Acidosis, Lactic; Adult; Asthma; Bicarbonates; Female; Humans; Infusions, Intravenous; Positive-Pres | 1989 |
Brain pH effects of NaHCO3 and Carbicarb in lactic acidosis.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Brain; Carbon Dioxide; Carbonates; Drug Combinations; Hydro | 1989 |
[Lactic acidosis in diabetic patients associated with buformin].
Topics: Acidosis, Lactic; Aged; Bicarbonates; Biguanides; Buformin; Diabetes Mellitus; Diabetic Angiopathies | 1989 |
Renal responses to exercise-induced lactic acidosis.
Topics: Acidosis, Lactic; Adult; Bicarbonates; Chlorides; Exercise; Glomerular Filtration Rate; Humans; Hydr | 1989 |
Bicarbonate haemodialysis: an adequate treatment for lactic acidosis in diabetics treated by metformin.
Topics: Acidosis, Lactic; Aged; Aged, 80 and over; Bicarbonates; Diabetes Mellitus; Female; Humans; Male; Me | 1987 |
Carbicarb: an effective substitute for NaHCO3 for the treatment of acidosis.
Topics: Acidosis, Lactic; Acidosis, Respiratory; Animals; Bicarbonates; Blood Gas Analysis; Blood Pressure; | 1987 |
Effects of bicarbonate on arterial and brain intracellular pH in neonatal rabbits recovering from hypoxic lactic acidosis.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Brain; Carbon Dioxide; Hydrogen-Ion Concentration; Hypoxia; | 1987 |
[Comparative effects of dichloroacetate and sodium bicarbonate on plasma lactic acid levels in experimentally produced hypoxia].
Topics: Acetates; Acidosis, Lactic; Animals; Bicarbonates; Dichloroacetic Acid; Dogs; Hemodynamics; Hypoxia; | 1987 |
Improved hemodynamic function during hypoxia with Carbicarb, a new agent for the management of acidosis.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Blood Gas Analysis; Carbonates; Cardiac Output; Dogs; Drug | 1988 |
Comparison of sodium bicarbonate with dichloroacetate treatment of hyperlactatemia and lactic acidosis in the ischemic rat.
Topics: Acetates; Acidosis, Lactic; Animals; Bicarbonates; Blood Glucose; Brain Chemistry; Brain Ischemia; D | 1988 |
Severe metabolic acidosis secondary to exertional hyperlactemia.
Topics: Acidosis, Lactic; Adult; Bicarbonates; Fluid Therapy; Humans; Infusions, Intravenous; Male; Physical | 1988 |
Effects of sodium bicarbonate in canine hemorrhagic shock.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Dogs; Hemodynamics; Lactates; Shock, Hemorrhagic; Sodium; S | 1988 |
[The diagnosis and therapy of lactic acidosis].
Topics: Acidosis, Lactic; Bicarbonates; Humans; Lactates; Lactic Acid; Male; Middle Aged; Sodium; Sodium Bic | 1988 |
The use of sodium bicarbonate in the therapy of organic acidosis.
Topics: Acidosis; Acidosis, Lactic; Animals; Bicarbonates; Calcium; Dogs; Heart Arrest; Humans; Hydrogen-Ion | 1986 |
Effect of dichloroacetate in the treatment of anoxic lactic acidosis in dogs.
Topics: Acetates; Acidosis, Lactic; Animals; Bicarbonates; Carbon Dioxide; Dichloroacetic Acid; Dogs; Heart | 1986 |
Survival from extreme lactic and keto-acidosis in diabetes mellitus.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Adult; Bicarbonates; Diabetes Mellitus, Type 1; Diabetic Ke | 1986 |
Bicarbonate therapy for organic acidosis: the case for its continued use.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Carbon Dioxide; Hemodynamics; Humans; Hydrogen-Ion Concentr | 1987 |
Bicarbonate therapy in severe acidosis.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Humans | 1988 |
Lactic acidosis and bicarbonate therapy.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Dogs; Humans | 1987 |
Lactate acidosis and the increase in VE/VO2 during incremental exercise.
Topics: Acidosis, Lactic; Adult; Bicarbonates; Blood; Humans; Hydrogen-Ion Concentration; Male; Oxygen Consu | 1987 |
Bicarbonate in severe lactic acidosis.
Topics: Acidosis, Lactic; Bicarbonates; Humans | 1987 |
Lactic acidosis and bicarbonate therapy.
Topics: Acidosis, Lactic; Animals; Bicarbonates; Dogs | 1987 |
Metabolic acidosis not due to lactic acidosis in patients with severe acute asthma.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Lactic; Adolescent; Adult; Aged; Asthma; Bicarbonates; Bl | 1987 |