hydrogen carbonate has been researched along with Intraocular Pressure in 27 studies
Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of acetazolamide on intraocular pressure (IOP) were studied on rabbits previously nephrectomized to eliminate the renal effects of the drug." | 3.66 | Ocular and systemic effects of acetazolamide in nephrectomized rabbits. ( Becker, B; Friedman, Z; Krupin, T, 1982) |
| "Systemic acidosis induced by intravenous administration of hydrochloric acid lowered intraocular pressure in unanesthetized rabbits." | 3.65 | Acidosis, alkalosis, and aqueous humor dynamics in rabbits. ( Bass, J; Becker, B; Krupin, T; Oestrich, CJ; Podos, SM, 1977) |
| "Treatment with dorzolamide reduced aqueous flow by 17%, and a maximum dose of acetazolamide alone reduced flow by 29%." | 2.69 | Aqueous humor flow in human eyes treated with dorzolamide and different doses of acetazolamide. ( Alm, A; Larsson, LI, 1998) |
| "Glaucoma is one of the major causes of blindness, affecting together with age-related macular degeneration > 70 million people worldwide." | 2.49 | Antiglaucoma carbonic anhydrase inhibitors: a patent review. ( Carta, F; Masini, E; Scozzafava, A; Supuran, CT, 2013) |
| "Glaucoma is a leading cause of blindness affecting as many as 2." | 1.37 | Regulation of anterior chamber drainage by bicarbonate-sensitive soluble adenylyl cyclase in the ciliary body. ( Buck, J; Hess, K; Lee, YS; Levin, LR; Marmorstein, AD; Marmorstein, LY; Tresguerres, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (77.78) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 1 (3.70) | 29.6817 |
| 2010's | 3 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Masini, E | 1 |
| Carta, F | 1 |
| Scozzafava, A | 1 |
| Supuran, CT | 1 |
| Liu, C | 1 |
| Cheng, Q | 1 |
| Nguyen, T | 1 |
| Bonanno, JA | 1 |
| Lee, YS | 1 |
| Tresguerres, M | 1 |
| Hess, K | 1 |
| Marmorstein, LY | 1 |
| Levin, LR | 1 |
| Buck, J | 1 |
| Marmorstein, AD | 1 |
| GREEN, H | 2 |
| MANN, MJ | 2 |
| WATERS, LP | 2 |
| CAMPBELL, DA | 1 |
| RENNER, NE | 1 |
| TONKS, E | 1 |
| BECKER, B | 3 |
| HEMPEL, AC | 1 |
| KOSAKI, H | 1 |
| NAKATANI, H | 1 |
| INOUE, Y | 1 |
| Spaeth, GL | 1 |
| Friedman, Z | 1 |
| Krupin, T | 2 |
| Shapiro, A | 1 |
| Shoenfeld, Y | 1 |
| Konikoff, F | 1 |
| Udassin, R | 1 |
| Shapiro, Y | 1 |
| Larsson, LI | 1 |
| Alm, A | 1 |
| Langford, MP | 1 |
| Chen, D | 1 |
| Neff, AG | 1 |
| Redens, TB | 1 |
| Berg, ME | 1 |
| Ganley, JP | 1 |
| Dass, P | 1 |
| Welbourne, TC | 1 |
| To, CH | 1 |
| Do, CW | 1 |
| Zamudio, AC | 1 |
| Candia, OA | 1 |
| Gaasterland, DE | 1 |
| Pederson, JE | 1 |
| MacLellan, HM | 1 |
| Oestrich, CJ | 1 |
| Bass, J | 1 |
| Podos, SM | 1 |
| Bird, CA | 1 |
| Gardner, AW | 1 |
| Roylance, PJ | 1 |
| Benedikt, O | 1 |
| Zirm, M | 1 |
| Harnoncourt, K | 1 |
| Sanchez, J | 1 |
| Hanna, C | 1 |
| Virno, M | 4 |
| Schirru, A | 2 |
| Pecori-Giraldi, J | 3 |
| Pellegrino, N | 2 |
| Giraldi, JP | 1 |
| Bietti, GB | 1 |
| Pivetti-Pezzi, P | 2 |
| Pecori Giraldi, J | 1 |
| Missiroli, A | 1 |
| Pivetti Pezzi, P | 1 |
| Leonardi, E | 1 |
| Toyofuku, H | 1 |
| Sevcík, J | 1 |
| Bonomi, L | 1 |
| Di Comite, P | 1 |
1 review available for hydrogen carbonate and Intraocular Pressure
| Article | Year |
|---|---|
Antiglaucoma carbonic anhydrase inhibitors: a patent review.
Topics: Animals; Aqueous Humor; Bicarbonates; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Drug Desig | 2013 |
1 trial available for hydrogen carbonate and Intraocular Pressure
| Article | Year |
|---|---|
Aqueous humor flow in human eyes treated with dorzolamide and different doses of acetazolamide.
Topics: Acetazolamide; Administration, Oral; Adult; Aqueous Humor; Bicarbonates; Carbonic Anhydrase Inhibito | 1998 |
25 other studies available for hydrogen carbonate and Intraocular Pressure
| Article | Year |
|---|---|
Knockdown of NBCe1 in vivo compromises the corneal endothelial pump.
Topics: Animals; Bicarbonates; Biological Transport, Active; Blotting, Western; Carbonic Anhydrase Inhibitor | 2010 |
Regulation of anterior chamber drainage by bicarbonate-sensitive soluble adenylyl cyclase in the ciliary body.
Topics: Adenylyl Cyclases; Animals; Aqueous Humor; Bestrophins; Bicarbonates; Chloride Channels; Ciliary Bod | 2011 |
Elaboration of bicarbonate ion in intraocular fluids. I. Aqueous humors, following intravenous infusion of sodium bicarbonate.
Topics: Aqueous Humor; Bicarbonates; Infusions, Intravenous; Intraocular Pressure; Sodium Bicarbonate | 1957 |
Elaboration of bicarbonate ion in intraocular fluids. I. Aqueous humors, following intravenous infusion of sodium bicarbonate.
Topics: Aqueous Humor; Bicarbonates; Infusions, Intravenous; Intraocular Pressure; Sodium Bicarbonate | 1957 |
Elaboration of bicarbonate ion in intraocular fluids. I. Aqueous humors, following intravenous infusion of sodium bicarbonate.
Topics: Aqueous Humor; Bicarbonates; Infusions, Intravenous; Intraocular Pressure; Sodium Bicarbonate | 1957 |
Elaboration of bicarbonate ion in intraocular fluids. I. Aqueous humors, following intravenous infusion of sodium bicarbonate.
Topics: Aqueous Humor; Bicarbonates; Infusions, Intravenous; Intraocular Pressure; Sodium Bicarbonate | 1957 |
Effect of diamox on plasma bicarbonate and on the electrolyte balance in relation to intra-ocular pressure in man.
Topics: Acetazolamide; Bicarbonates; Electrolytes; Humans; Intraocular Pressure; Male; Plasma; Tonometry, Oc | 1958 |
OUABAIN AND AQUEOUS HUMOR DYNAMICS IN THE RABBIT EYE.
Topics: Animals; Aqueous Humor; Ascorbic Acid; Bicarbonates; Eye Proteins; Injections; Intraocular Pressure; | 1963 |
THE RELATIONSHIP OF THE MAJOR CONSTITUENTS OF BLOOD PLASMA TO THE INTRAOCULAR PRESSURE DURING PHASIC VARIATIONS AND AMMONIUM CHLORIDE ADMINISTRATION.
Topics: Ammonium Chloride; Bicarbonates; Blood; Blood Proteins; Chlorides; Glaucoma; Humans; Intraocular Pre | 1964 |
[STUDIES ON OCULAR RIGIDITY WITH CLOSED MANOMETER SYSTEM].
Topics: Acetazolamide; Animals; Bicarbonates; Eye; Glucose; Hypertonic Solutions; Intraocular Pressure; Mano | 1964 |
Potassium, acetazolamide, and intraocular pressure.
Topics: Acetazolamide; Adult; Aged; Bicarbonates; Child; Chlorides; Electrocardiography; Female; Glaucoma; H | 1967 |
Ocular and systemic effects of acetazolamide in nephrectomized rabbits.
Topics: Acetazolamide; Animals; Aqueous Humor; Bicarbonates; Blood; Carbon Dioxide; Eye; Hydrogen-Ion Concen | 1982 |
The relationship between body temperature and intraocular pressure.
Topics: Acclimatization; Adult; Bicarbonates; Body Temperature; Hematocrit; Humans; Intraocular Pressure; Ma | 1981 |
Intracameral muramyl dipeptide-induced paracellular permeability associated with decreased glutamate transporter and gamma -glutamyltranspeptidase activities.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Amino Acid Transport System X-AG; Animals; Aqueous Humor; ATP-Bin | 1999 |
Model of ionic transport for bovine ciliary epithelium: effects of acetazolamide and HCO.
Topics: Acetazolamide; Animals; Aqueous Humor; Bicarbonates; Biological Transport; Carbon Radioisotopes; Car | 2001 |
Perfusate effects upon resistance to aqueous humor outflow in the rhesus monkey eye. A comparison of glutathione-bicarbonate Ringer's solution to pooled aqueous humor as perfusate.
Topics: Animals; Anterior Chamber; Aqueous Humor; Bicarbonates; Glutathione; Haplorhini; Intraocular Pressur | 1978 |
Acidosis, alkalosis, and aqueous humor dynamics in rabbits.
Topics: Acidosis; Alkalosis; Animals; Aqueous Humor; Bicarbonates; Blood Pressure; Body Temperature; Hydroch | 1977 |
Letter: Danger of saline emetics in first-aid for poisoning.
Topics: Adult; Bicarbonates; Child, Preschool; Chlorides; Emetics; Female; First Aid; Heart Failure; Humans; | 1974 |
[Relations between metabolic acidosis and intraocular pressure after inhibition of carboanhydrase with acetazolamide (author's transl)].
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis; Aqueous Humor; Bicarbonates; Buffers; Carbonic Anhyd | 1974 |
Effects of acetazolamide on concentration of free amino acids in aqueous fluid.
Topics: Acetazolamide; Amino Acids; Aqueous Humor; Bicarbonates; Chlorides; Humans; Intraocular Pressure; Me | 1969 |
Aqueous humor alkalosis and marked reduction in ocular ascorbic acid content following long-term topical cortisone (9alpha-fluoro-16alpha-methylprednisolone).
Topics: Alkalosis; Animals; Aqueous Humor; Ascorbic Acid; Bicarbonates; Dexamethasone; Eye; Hydrogen-Ion Con | 1974 |
Topical corticosteroids and vitreous dynamics in the rabbit.
Topics: Acid-Base Equilibrium; Administration, Topical; Animals; Aqueous Humor; Ascorbic Acid; Bicarbonates; | 1973 |
[Blood acidosis and intraocular hypotension].
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis; Animals; Aqueous Humor; Ascorbic Acid; Bicarbonates; | 1972 |
[Studies on the ocular hypotonizing effects and on blood acidosis induced by ascorbic acid administered orally. (Research on man and animal)].
Topics: Acid-Base Equilibrium; Acidosis; Administration, Oral; Animals; Aqueous Humor; Ascorbic Acid; Bicarb | 1970 |
[Ocular hypotonic effect of hematic acidifying agents: carbonic anhydrase inhibitors].
Topics: Acetazolamide; Animals; Aqueous Humor; Bicarbonates; Carbon Dioxide; Carbonic Anhydrase Inhibitors; | 1970 |
[Effect of osmotic agents on the formation of aqueous humor].
Topics: Animals; Aqueous Humor; Bicarbonates; Fluoresceins; Glaucoma; Glycerol; Humans; Intraocular Pressure | 1968 |
[Effect of bicarbonates and chlorides on the flow equilibrium of the eye].
Topics: Acid-Base Equilibrium; Aqueous Humor; Bicarbonates; Chlorides; Glaucoma; Humans; Infusions, Parenter | 1969 |
[Research on the composition of the aqueous humor after pharmacological ocular sympathetic block in the rabbit. VI. Behavior of bicarbonates].
Topics: Animals; Aqueous Humor; Bicarbonates; Intraocular Pressure; Rabbits; Sympathectomy | 1965 |