hydrogen carbonate has been researched along with HbS Disease in 44 studies
Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The treatment of sickle cell disease is still mainly symptomatic." | 2.38 | Management of sickle cell disease: a review. ( Aluoch, JR, 1991) |
| "The treatment of sickle cell disease is still primarily symptomatic." | 2.36 | Current concepts in the treatment of sickle cell disease. ( Aluoch, JR, 1983) |
| "Niprisan® is an herbal medicine for sickle cell anemia developed in the National Institute for Pharmaceutical Research and Development (NIPRD)." | 1.36 | A normative study of the components of niprisan--an herbal medicine for sickle cell anemia. ( Ache, TA; Afolabi, EK; Ameh, SJ; Ibe, MC; Inyang, US; Obodozie, OO; Onanuga, CE; Oyedele, EO, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (86.36) | 18.7374 |
| 1990's | 4 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Masy, V | 1 |
| Sokal, E | 1 |
| Ranguelov, N | 1 |
| Brichard, B | 1 |
| Laterre, PF | 1 |
| Hantson, P | 1 |
| Obodozie, OO | 1 |
| Ameh, SJ | 1 |
| Afolabi, EK | 1 |
| Oyedele, EO | 1 |
| Ache, TA | 1 |
| Onanuga, CE | 1 |
| Ibe, MC | 1 |
| Inyang, US | 1 |
| APTHORP, GH | 1 |
| MEASDAY, B | 1 |
| LEHMANN, H | 4 |
| SCHWARTZ, E | 1 |
| MCELFRESH, AE | 1 |
| APTHROP, GH | 1 |
| HUGH-JONES, K | 1 |
| MCALISTER, JM | 1 |
| BARRERAS, L | 2 |
| DIGGS, LW | 2 |
| BROWNE, RA | 1 |
| FINNEY, RA | 1 |
| HATCH, FE | 1 |
| Bookchin, RM | 1 |
| Lew, DJ | 1 |
| Balazs, T | 1 |
| Ueda, Y | 1 |
| Lew, VL | 1 |
| Guberti, A | 1 |
| Marchi, M | 1 |
| Tartari, S | 1 |
| Pavani, A | 1 |
| Franchella, A | 1 |
| Georgacopulo, P | 1 |
| Aluoch, JR | 2 |
| Orringer, EP | 1 |
| Roer, ME | 1 |
| Parker, JC | 1 |
| Godart, H | 1 |
| Dormandy, A | 1 |
| Ellory, JC | 2 |
| Gibson, JS | 1 |
| Stewart, GW | 1 |
| Elisaf, MS | 1 |
| Siamopoulos, KC | 1 |
| Oster, JR | 2 |
| Lee, SM | 2 |
| Lespier, LE | 2 |
| Pellegrini, EL | 2 |
| Vaamonde, CA | 2 |
| Marynick, SP | 1 |
| Ramsey, EJ | 1 |
| Knochel, JP | 2 |
| Machado, MC | 1 |
| D'Albuquerque, LA | 1 |
| da Cunha, JE | 1 |
| Bacchella, T | 1 |
| Faintuch, J | 1 |
| Rivadeneira, GE | 1 |
| Parshall, CJ | 2 |
| Vainisi, SJ | 2 |
| Goldberg, MF | 2 |
| Wolf, ED | 2 |
| Miller, GJ | 1 |
| Serjeant, GR | 1 |
| Meyersfield, SA | 1 |
| Morganstern, SL | 1 |
| Seery, W | 1 |
| Cole, AT | 1 |
| Green, M | 1 |
| Hall, RJ | 1 |
| Huntsman, RG | 3 |
| Lawson, A | 1 |
| Pearson, TC | 1 |
| Wheeler, PC | 1 |
| Billett, HH | 1 |
| Kaul, DK | 1 |
| Connel, MM | 1 |
| Fabry, ME | 1 |
| Nagel, RL | 1 |
| Mann, JR | 2 |
| Deeble, TJ | 1 |
| Breeze, GR | 1 |
| Stuart, J | 2 |
| Guy, RB | 1 |
| Rothenberg, SP | 1 |
| Howells, TH | 1 |
| Labbe, RF | 1 |
| Addae, S | 1 |
| Ringelhann, B | 1 |
| Konotey-Ahulu, FI | 1 |
| Kong, HH | 1 |
| Alleyne, GA | 1 |
| Olver, RE | 1 |
| Kabins, SA | 1 |
| Lerner, C | 1 |
| Knight, R | 1 |
| Woodruff, AW | 1 |
| Pettitt, LE | 1 |
| Williams, G | 1 |
| Murray, RS | 1 |
4 reviews available for hydrogen carbonate and HbS Disease
| Article | Year |
|---|---|
Current concepts in the treatment of sickle cell disease.
Topics: Adult; Altitude; Analgesics; Anemia, Sickle Cell; Bicarbonates; Blood Transfusion; Child; Child, Pre | 1983 |
Pathophysiology of abnormal cell volume in human red cells.
Topics: Anemia, Hemolytic, Congenital; Anemia, Sickle Cell; Bicarbonates; Carrier Proteins; Cell Membrane Pe | 1998 |
Management of sickle cell disease: a review.
Topics: Anemia, Sickle Cell; Bicarbonates; Blood Transfusion; Fluid Therapy; Genetic Counseling; Humans; Oxy | 1991 |
Sickle cell crisis.
Topics: Abdomen, Acute; Abortion, Therapeutic; Acidosis; Anemia, Sickle Cell; Bicarbonates; Citrates; Dehydr | 1973 |
5 trials available for hydrogen carbonate and HbS Disease
| Article | Year |
|---|---|
Pentoxifylline (Trental) has no significant effect on laboratory parameters in sickle cell disease.
Topics: Administration, Oral; Adult; Anemia, Sickle Cell; Bicarbonates; Blood Cell Count; Blood Viscosity; D | 1989 |
Ancrod in sickle-cell crisis.
Topics: Acute Disease; Anemia, Sickle Cell; Anticoagulants; Bicarbonates; Child; Child, Preschool; Female; F | 1972 |
Editorial: Treatment of sickle-cell crises.
Topics: Anemia, Sickle Cell; Bicarbonates; Clinical Trials as Topic; Drug Evaluation; Hexoses; Humans; Infus | 1974 |
Clinical trials of therapy for sickle cell vaso-occlusive crises. Cooperative urea trials group.
Topics: Alkalies; Anemia, Sickle Cell; Arterial Occlusive Diseases; Bicarbonates; Blood Urea Nitrogen; Evalu | 1974 |
Sodium bicarbonate prophylaxis of sickle cell crisis.
Topics: Administration, Oral; Adolescent; Anemia, Sickle Cell; Bicarbonates; Child; Child, Preschool; Clinic | 1974 |
35 other studies available for hydrogen carbonate and HbS Disease
| Article | Year |
|---|---|
Fatal type B lactic acidosis in a patient with end-stage liver disease related to homozygous sickle cell disease.
Topics: Acidosis, Lactic; Adolescent; Anemia, Sickle Cell; Bicarbonates; Catheter-Related Infections; End St | 2019 |
A normative study of the components of niprisan--an herbal medicine for sickle cell anemia.
Topics: Anemia, Sickle Cell; Bicarbonates; Herbal Medicine; Humans; Hydrogen-Ion Concentration; Phytotherapy | 2010 |
Pregnancy in sickle-cell anaemia.
Topics: Anemia; Anemia, Sickle Cell; Bicarbonates; Female; Humans; Pregnancy; Pregnancy Complications | 1963 |
TREATMENT OF PAINFUL CRISES OF SICKLE CELL DISEASE. A DOUBLE BLIND STUDY.
Topics: Anemia; Anemia, Sickle Cell; Bicarbonates; Child; Double-Blind Method; Erythrocytes, Abnormal; Human | 1964 |
SICKLE-CELL ANAEMIA.
Topics: Anemia, Sickle Cell; Bicarbonates; Blood Protein Electrophoresis; Cesarean Section; Female; Humans; | 1964 |
SOME EXPERIENCES IN MANAGING SICKLE-CELL ANAEMIA IN CHILDREN AND YOUNG ADULTS, USING ALKALIS AND MAGNESIUM.
Topics: Acidosis; Adolescent; Adult; Alkalies; Anemia, Sickle Cell; Bicarbonates; Blood Protein Electrophore | 1964 |
BICARBONATES, PH AND PERCENTAGE OF SICKLED CELLS IN VENOUS BLOOD OF PATIENTS IN SICKLE CELL CRISIS.
Topics: Anemia; Anemia, Sickle Cell; Bicarbonates; Blood; Erythrocyte Count; Hemoglobins; Hemoglobins, Abnor | 1964 |
ANAESTHESIA IN PATIENTS WITH SICKLE-CELL ANAEMIA.
Topics: Anemia, Sickle Cell; Anesthesia; Bicarbonates; Blood Transfusion; Humans; Oxygen Inhalation Therapy; | 1965 |
EFFECT OF A CARBONIC ANHYDRASE INHIBITOR (DICHLORPHENAMIDE) ON SICKLE CELL ANEMIA.
Topics: Acidosis; Anemia; Anemia, Sickle Cell; Bicarbonates; Carbonic Anhydrase Inhibitors; Dichlorphenamide | 1965 |
Dehydration and delayed proton equilibria of red blood cells suspended in isosmotic phosphate buffers. Implications for studies of sickled cells.
Topics: Anemia, Sickle Cell; Bicarbonates; Buffers; Chlorides; Erythrocytes; Hemoglobins; Humans; Hydrogen-I | 1984 |
[Anesthesia and sickle cell disease].
Topics: Acidosis; Adolescent; Anemia, Sickle Cell; Anesthesia; Bicarbonates; Blood Viscosity; Child; Child, | 1984 |
Cell density profile as a measure of erythrocyte hydration: therapeutic alteration of salt and water content in normal and SS red blood cells.
Topics: Anemia, Sickle Cell; Bicarbonates; Chromium Radioisotopes; Erythrocytes; Humans; Potassium; Sodium; | 1980 |
Do HbSS erythrocytes lose KCl in physiological conditions?
Topics: Adolescent; Adult; Anemia, Sickle Cell; Bicarbonates; Erythrocytes; Ethylmaleimide; Female; Humans; | 1997 |
A man from Surinam... (Hyperventilation after drug abuse: how are the observed acid-base and electrolyte abnormalities interpreted?)
Topics: Acid-Base Imbalance; Anemia, Sickle Cell; Bicarbonates; Electrolytes; Humans; Hyperventilation; Male | 1998 |
Renal acidification in sickle cell trait.
Topics: Acidosis, Renal Tubular; Adult; Ammonium Chloride; Anemia, Sickle Cell; Bicarbonates; Blood; Carbon | 1976 |
Renal acidification in sickle-cell disease.
Topics: Acidosis, Renal Tubular; Adolescent; Adult; Anemia, Sickle Cell; Bicarbonates; Carbon Dioxide; Eryth | 1976 |
The effect of bicarbonate and distilled water on sickle cell trait hematuria and in vitro studies on the interaction of osmolality and pH on erythrocyte sickling in sickle cell trait.
Topics: Adult; Anemia, Sickle Cell; Bicarbonates; Erythrocytes, Abnormal; Female; Hematuria; Hemoglobins; Hu | 1977 |
[Complications associated with biliary surgery in patients with sickle cell anemia].
Topics: Acidosis; Adolescent; Adult; Anemia, Sickle Cell; Bicarbonates; Blood Transfusion; Cholecystectomy; | 1979 |
In vivo erythrocyte sickling in the Japanese sika deer (Cervus nippon): methodology.
Topics: Alkalosis; Anemia, Sickle Cell; Anesthesia, Inhalation; Animals; Bicarbonates; Carbon Dioxide; Deer; | 1975 |
Ventilatory response to carbon dioxide in sickle-cell disease.
Topics: Anemia, Sickle Cell; Bicarbonates; Carbon Dioxide; Humans; Respiration | 1977 |
Medical management of refractory hematuria in sickle-cell trait.
Topics: Acetazolamide; Adult; Anemia, Sickle Cell; Bicarbonates; Drug Therapy, Combination; Female; Ferrous | 1976 |
Ophthalmic manifestations of induced sickling of erythrocytes in Japanese sika deer (Cervus nippon).
Topics: Alkalosis; Anemia, Sickle Cell; Animals; Bicarbonates; Deer; Electroretinography; Erythrocytes; Eye | 1975 |
Sickle cell crisis treated by exchange transfusion. Treatment of two patients with heterozygous sickle cell syndrome.
Topics: Adult; Anemia, Sickle Cell; Bicarbonates; Calcium; Chlorides; Exchange Transfusion, Whole Blood; Fev | 1975 |
Treatment of sickle-cell disease.
Topics: Anemia, Sickle Cell; Anesthesia; Anticoagulants; Aspirin; Bicarbonates; Blood; Blood Flow Velocity; | 1974 |
Anaesthesia in sickle cell states.
Topics: Anemia, Sickle Cell; Anesthesia, General; Bicarbonates; Genotype; Humans; Hypoxia | 1973 |
Sodium cyanate: chemical properties relevant to sickle cell disease therapy.
Topics: Anemia, Sickle Cell; Bicarbonates; Chemical Phenomena; Chemistry; Cyanates; Drug Stability; Hydrogen | 1973 |
Sodium citrate orally for painful sickle cell crises.
Topics: Acetazolamide; Adult; Ammonium Chloride; Anemia, Sickle Cell; Bicarbonates; Citrates; Codeine; Fever | 1971 |
Effect of acute temperature change in some renal functions in sickle cell disease.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anemia, Sickle Cell; Bicarbonates; Female; Hemodynamics; | 1971 |
Sickle cell crisis and acid-base balance.
Topics: Acid-Base Equilibrium; Acidosis; Adolescent; Adult; Anemia, Sickle Cell; Bicarbonates; Blood Chemica | 1971 |
Studies on acid excretion in adults with sickle-cell anaemia.
Topics: Acidosis, Renal Tubular; Acids; Adolescent; Adult; Ammonium Chloride; Anemia, Sickle Cell; Bicarbona | 1971 |
Severe acidosis during a painful sickle cell crisis.
Topics: Acidosis; Acidosis, Respiratory; Anemia, Sickle Cell; Bicarbonates; Blood Pressure; Child, Preschool | 1969 |
Fulminant pneumococcemia and sickle cell anemia.
Topics: Acute Disease; Adolescent; Adult; Anemia, Sickle Cell; Bicarbonates; Child; Child, Preschool; Erythr | 1970 |
Some applications of radiochromium 51Cr in assessing the value of therapeutic regimes and the effects of crises in haemoglobinopathic states.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Bicarbonates; Blood Chemical Analysis; Child; Chlorpromazine | 1968 |
Hematuria in sickle cell trait: the effect of intravenous administration of distilled water, urinary alkalinization, and diuresis.
Topics: Adult; Anemia, Sickle Cell; Bicarbonates; Blood Cell Count; Creatinine; Cystoscopy; Diuresis; Erythr | 1969 |
Haematuria and sickle-cell trait.
Topics: Adult; Anemia, Sickle Cell; Bicarbonates; Electrophoresis; Female; Hematuria; Hemoglobins, Abnormal; | 1969 |