hydrogen carbonate has been researched along with Gaucher Disease in 1 studies
Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.
Gaucher Disease: An autosomal recessive disorder caused by a deficiency of acid beta-glucosidase (GLUCOSYLCERAMIDASE) leading to intralysosomal accumulation of glycosylceramide mainly in cells of the MONONUCLEAR PHAGOCYTE SYSTEM. The characteristic Gaucher cells, glycosphingolipid-filled HISTIOCYTES, displace normal cells in BONE MARROW and visceral organs causing skeletal deterioration, hepatosplenomegaly, and organ dysfunction. There are several subtypes based on the presence and severity of neurological involvement.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| van der Lienden, MJC | 1 |
| Aten, J | 1 |
| Boot, RG | 1 |
| van Eijk, M | 1 |
| Aerts, JMFG | 1 |
| Kuo, CL | 1 |
1 other study available for hydrogen carbonate and Gaucher Disease
| Article | Year |
|---|---|
HEPES-buffering of bicarbonate-containing culture medium perturbs lysosomal glucocerebrosidase activity.
Topics: Bicarbonates; Gaucher Disease; Glucosylceramidase; HEPES; Humans; Lysosomes | 2022 |