hydrogen carbonate has been researched along with Gastroenteritis in 46 studies
Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.
Gastroenteritis: INFLAMMATION of any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Causes of gastroenteritis are many including genetic, infection, HYPERSENSITIVITY, drug effects, and CANCER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The clinical dehydration scale (CDS) is a quick, easy-to-use tool with 4 clinical items and a score of 1-8 that serves to classify dehydration in children with gastroenteritis as no, some or moderate/severe dehydration." | 2.79 | Comparison of clinical and biochemical markers of dehydration with the clinical dehydration scale in children: a case comparison trial. ( Filler, G; Lepage, N; Plint, A; Tam, RK; Wong, H, 2014) |
| "On admission, degree of dehydration, biochemical and haematological parameters were similar." | 2.66 | Oral rehydration therapy without bicarbonate for prevention and treatment of dehydration: a double-blind controlled trial. ( Armitstead, JC; Elliott, EJ; Farthing, MJ; Walker-Smith, JA, 1988) |
| "Acute gastroenteritis is defined as a diarrheal disease of rapid onset, with or without nausea, vomiting, fever, or abdominal pain." | 2.61 | Gastroenteritis in Children. ( Brown, E; Hartman, S; Loomis, E; Russell, HA, 2019) |
| "Overestimating dehydration may lead to overtreatment with intravenous fluids or unnecessary hospitalization, whereas underestimation may lead to delayed therapy and aggravation of symptoms." | 1.46 | Usefulness of end-tidal carbon dioxide as an indicator of dehydration in pediatric emergency departments: A retrospective observational study. ( Jeon, W; Lee, JS; Min, YG; Yang, HW, 2017) |
| "Most patients with dehydration caused by gastroeneritis who need more treatment and observation than can reasonably be offered in an emergency department setting should be considered for OU admission regardless of their historical or laboratory characteristics." | 1.33 | Use of a pediatric observation unit for treatment of children with dehydration caused by gastroenteritis. ( Kadish, H; Mallory, MD; Nelson, D; Zebrack, M, 2006) |
| "Oral rehydration is an ideal form of treatment of gastroenteritis in India both in large hsopitals and in rural health centers where adequate facilities and trained personnel are lacking." | 1.25 | Oral rehydration in gastroenteritis in children. ( Mazumdar, H; Zingde, KD, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (56.52) | 18.7374 |
| 1990's | 3 (6.52) | 18.2507 |
| 2000's | 8 (17.39) | 29.6817 |
| 2010's | 8 (17.39) | 24.3611 |
| 2020's | 1 (2.17) | 2.80 |
| Authors | Studies |
|---|---|
| Marzuillo, P | 1 |
| Baldascino, M | 1 |
| Guarino, S | 1 |
| Perrotta, S | 1 |
| Miraglia Del Giudice, E | 1 |
| Nunziata, F | 1 |
| Yang, HW | 1 |
| Jeon, W | 1 |
| Min, YG | 1 |
| Lee, JS | 1 |
| Hartman, S | 1 |
| Brown, E | 1 |
| Loomis, E | 1 |
| Russell, HA | 1 |
| De Lisle, RC | 1 |
| Borowitz, D | 1 |
| Freedman, SB | 2 |
| DeGroot, JM | 1 |
| Parkin, PC | 2 |
| Tam, RK | 1 |
| Wong, H | 1 |
| Plint, A | 1 |
| Lepage, N | 1 |
| Filler, G | 1 |
| Allen, CH | 1 |
| Goldman, RD | 2 |
| Bhatt, S | 1 |
| Simon, HK | 1 |
| Gorelick, MH | 1 |
| Spandorfer, PR | 1 |
| Spiro, DM | 1 |
| Mace, SE | 1 |
| Johnson, DW | 1 |
| Higginbotham, EA | 1 |
| Du, H | 1 |
| Smyth, BJ | 1 |
| Schermer, CR | 1 |
| Goldstein, SL | 1 |
| Madati, PJ | 1 |
| Bachur, R | 1 |
| Fujita, T | 1 |
| Shimooka, T | 1 |
| Teraoka, Y | 1 |
| Sugita, Y | 1 |
| Kaito, H | 1 |
| Iijima, K | 1 |
| Matsuo, M | 1 |
| Nozu, K | 1 |
| Tanaka, R | 1 |
| Macarthur, C | 1 |
| Khambalia, A | 1 |
| Friedman, JN | 1 |
| Kinlin, LM | 1 |
| KILDEBERG, P | 1 |
| Mallory, MD | 1 |
| Kadish, H | 1 |
| Zebrack, M | 1 |
| Nelson, D | 1 |
| Nagler, J | 1 |
| Wright, RO | 1 |
| Krauss, B | 1 |
| Costantino, M | 1 |
| Giuberti, G | 1 |
| Caraglia, M | 1 |
| Lombardi, A | 1 |
| Misso, G | 1 |
| Abbruzzese, A | 1 |
| Ciani, F | 1 |
| Lampa, E | 1 |
| Harrison, VC | 2 |
| de Heese, HV | 2 |
| Bowie, MD | 2 |
| Rubin, R | 1 |
| Lacroix, J | 1 |
| Chicoine, L | 1 |
| Price, HV | 1 |
| Dodge, JA | 1 |
| Thomas, MK | 1 |
| Narchi, H | 2 |
| Booth, IW | 1 |
| Lin, SL | 1 |
| Kong, MS | 1 |
| Brewster, D | 1 |
| Yilmaz, K | 1 |
| Karaböcüoglu, M | 1 |
| Citak, A | 1 |
| Uzel, N | 1 |
| Banister, A | 1 |
| Matin-Siddiqi, SA | 1 |
| Hatcher, GW | 1 |
| Naik, NV | 1 |
| Shah, PM | 1 |
| Bonadio, WA | 1 |
| Hennes, HH | 1 |
| Machi, J | 1 |
| Madagame, E | 1 |
| Elliott, EJ | 1 |
| Armitstead, JC | 1 |
| Farthing, MJ | 1 |
| Walker-Smith, JA | 1 |
| Davidson, GP | 1 |
| Rivkees, SA | 1 |
| Fine, BP | 1 |
| Choudhuri, PK | 1 |
| Voloshin, AI | 1 |
| Khristich, TN | 1 |
| Santhanakrishnan, BR | 1 |
| Kumaresan, G | 1 |
| Raju, VB | 1 |
| Peat, G | 1 |
| Ironside, AG | 1 |
| Rubens, RD | 1 |
| Lambert, HP | 1 |
| Mazumdar, H | 1 |
| Zingde, KD | 1 |
| Buchanan, N | 1 |
| Eyberg, C | 1 |
| Helwig, H | 1 |
| Prinsloo, JG | 1 |
| Kruger, H | 1 |
| Laubscher, NF | 1 |
| Botha, MA | 1 |
| Ahmed, I | 1 |
| Agusto-Odutola, TB | 1 |
| Martin, C | 1 |
| Beauvieux, YJ | 1 |
| Bildstein, G | 1 |
| Brown, J | 1 |
| Albert, MS | 1 |
| Rahill, WJ | 1 |
| Vega, L | 1 |
| Winters, RW | 1 |
| Tonin, C | 1 |
| Evans, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Emergency Department Rapid Intravenous Rehydration (RIVR) for Pediatric Gastroenteritis: A Randomized Controlled Trial[NCT00392145] | Phase 4 | 226 participants (Actual) | Interventional | 2006-11-30 | Completed | ||
| Cystatin C as a Marker for Detecting Early Renal Dysfunction in a Pediatric Emergency Department[NCT00462527] | 464 participants (Anticipated) | Observational | 2007-05-31 | Completed | |||
| A Double-Blind, Randomized, Comparative Efficacy and Safety Trial of Intravenous Solutions for the Treatment of Moderate to Severe Dehydration in Children With Acute Gastroenteritis[NCT01234883] | Phase 4 | 100 participants (Actual) | Interventional | 2011-06-30 | Terminated (stopped due to Insufficient enrollment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The primary efficacy variable was venous serum bicarbonate (marker of metabolic acidosis) at Hour 4 (+/- 1 hour) from the start of the First IV Bolus. (NCT01234883)
Timeframe: Day 1 (4 Hours after start of IV)
| Intervention | mmol/L (Mean) |
|---|---|
| Multiple Electrolyte Solution | 1.63 |
| Saline | 0.00 |
4 reviews available for hydrogen carbonate and Gastroenteritis
| Article | Year |
|---|---|
Gastroenteritis in Children.
Topics: Adolescent; Antiemetics; Bicarbonates; Child; Child, Preschool; Dehydration; Fluid Therapy; Gastroen | 2019 |
The cystic fibrosis intestine.
Topics: Animals; Bicarbonates; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease | 2013 |
Dehydration in acute gastroenteritis.
Topics: Acute Disease; Australia; Bicarbonates; Blood Chemical Analysis; Child; Child, Preschool; Dehydratio | 2002 |
Viral diarrhoea.
Topics: Bicarbonates; Child; Child, Preschool; Diarrhea; Diarrhea, Infantile; Fluid Therapy; Gastroenteritis | 1986 |
7 trials available for hydrogen carbonate and Gastroenteritis
| Article | Year |
|---|---|
Successful discharge of children with gastroenteritis requiring intravenous rehydration.
Topics: Administration, Intravenous; Antiemetics; Bicarbonates; Biomarkers; Child; Child, Preschool; Dehydra | 2014 |
Comparison of clinical and biochemical markers of dehydration with the clinical dehydration scale in children: a case comparison trial.
Topics: Adolescent; Bicarbonates; Biomarkers; Blood Pressure; Child; Child, Preschool; Creatinine; Dehydrati | 2014 |
A randomized trial of Plasma-Lyte A and 0.9 % sodium chloride in acute pediatric gastroenteritis.
Topics: Bicarbonates; Child; Child, Preschool; Dehydration; Double-Blind Method; Electrolytes; Gastroenterit | 2016 |
Extremely low sodium hypotonic rehydration solution for young children with acute gastroenteritis.
Topics: Acute Disease; Bicarbonates; Fluid Therapy; Gastroenteritis; Glucose; Humans; Hypotonic Solutions; I | 2001 |
Oral rehydration in acute gastro-enteritis in young children.
Topics: Acute Disease; Administration, Oral; Bicarbonates; Child, Preschool; Chlorides; Gastroenteritis; Glu | 1976 |
Oral rehydration therapy without bicarbonate for prevention and treatment of dehydration: a double-blind controlled trial.
Topics: Acidosis; Bicarbonates; Child, Preschool; Dehydration; Double-Blind Method; Fluid Therapy; Gastroent | 1988 |
Management of metabolic acidosis in acute gastro-enteritis.
Topics: Acidosis; Bicarbonates; Child, Preschool; Dehydration; Gastroenteritis; Glucose; Humans; Infant; Inf | 1966 |
35 other studies available for hydrogen carbonate and Gastroenteritis
| Article | Year |
|---|---|
Acute kidney injury in children hospitalized for acute gastroenteritis: prevalence and risk factors.
Topics: Acute Kidney Injury; Bicarbonates; Child, Preschool; Creatinine; Dehydration; ErbB Receptors; Female | 2021 |
Usefulness of end-tidal carbon dioxide as an indicator of dehydration in pediatric emergency departments: A retrospective observational study.
Topics: Acidosis; Adolescent; Bicarbonates; Capnography; Child; Child, Preschool; Dehydration; Diabetic Keto | 2017 |
Development of an emergency department triage tool to predict acidosis among children with gastroenteritis.
Topics: Acidosis; Acute Disease; Bicarbonates; Breath Tests; Carbon Dioxide; Child; Child, Preschool; Decisi | 2008 |
Acute renal failure due to obstructive uric acid stones associated with acute gastroenteritis.
Topics: Acute Kidney Injury; Bicarbonates; Child, Preschool; Gastroenteritis; Humans; Infant; Male; Nephrost | 2009 |
Clinical and laboratory assessment of dehydration severity in children with acute gastroenteritis.
Topics: Acute Disease; Bicarbonates; Body Weight; Child, Preschool; Dehydration; Diagnosis, Differential; Em | 2010 |
Evaluation of a clinical dehydration scale in children requiring intravenous rehydration.
Topics: Bicarbonates; Body Weight; Child, Preschool; Cohort Studies; Dehydration; Emergency Service, Hospita | 2012 |
METABOLIC ACIDOSIS IN INFANTILE GASTROENTERITIS. PHYSIOLOGIC AND THERAPEUTIC ASPECTS.
Topics: Acidosis; Adrenal Insufficiency; Bicarbonates; Blood; Child; Dehydration; Diarrhea; Diarrhea, Infant | 1965 |
Use of a pediatric observation unit for treatment of children with dehydration caused by gastroenteritis.
Topics: Bicarbonates; Child; Child, Preschool; Dehydration; Electrolytes; Female; Gastroenteritis; Hospital | 2006 |
End-tidal carbon dioxide as a measure of acidosis among children with gastroenteritis.
Topics: Acidosis, Respiratory; Area Under Curve; Bicarbonates; Breath Tests; Capnography; Carbon Dioxide; Fe | 2006 |
Possible antioxidant role of SPA therapy with chlorine-sulphur-bicarbonate mineral water.
Topics: Animals; Antioxidants; Balneology; Bicarbonates; Body Weight; Chlorine; Female; Gastroenteritis; Mal | 2009 |
The rapid correction of metabolic acidosis in severely dehydrated infants.
Topics: Acidosis; Bicarbonates; Body Temperature; Calcium; Carbon Dioxide; Dehydration; Gastroenteritis; Hum | 1967 |
[Metabolic alkalosis in a newborn infant caused by topical application of bicarbonate].
Topics: Administration, Topical; Alkalosis; Bicarbonates; Diaper Rash; Gastroenteritis; Humans; Hypernatremi | 1982 |
Oral rehydration without added bicarbonate for childhood gastroenteritis.
Topics: Bicarbonates; Child, Preschool; England; Female; Fluid Therapy; Gastroenteritis; Humans; Infant; Inf | 1984 |
Serum bicarbonate and dehydration severity in gastroenteritis.
Topics: Bicarbonates; Biomarkers; Child, Preschool; Dehydration; Female; Gastroenteritis; Humans; Infant; Ma | 1998 |
Serum bicarbonate and the severity of dehydration in gastroenteritis.
Topics: Bicarbonates; Dehydration; Gastroenteritis; Humans; Predictive Value of Tests | 1998 |
Serum bicarbonate and the severity of dehydration in gastroenteritis.
Topics: Bicarbonates; Biomarkers; Child; Dehydration; Gastroenteritis; Humans | 1999 |
Evaluation of laboratory tests in dehydrated children with acute gastroenteritis.
Topics: Acute Disease; Bicarbonates; Blood Chemical Analysis; Clinical Laboratory Techniques; Diarrhea, Infa | 2002 |
Treatment of hypernatraemic dehydration in infancy.
Topics: Bicarbonates; Body Weight; Dehydration; Gastroenteritis; Humans; Hyperglycemia; Hypernatremia; Hypoc | 1975 |
Efficacy of measuring BUN in assessing children with dehydration due to gastroenteritis.
Topics: Bicarbonates; Blood Urea Nitrogen; Child; Child, Preschool; Dehydration; Gastroenteritis; Humans; In | 1989 |
The reliability of calculated bicarbonate in clinical practice.
Topics: Acid-Base Imbalance; Acute Disease; Adult; Bicarbonates; Blood Gas Analysis; Clinical Competence; Di | 1988 |
Acute gastroenteritis in children.
Topics: Acute Disease; Anti-Bacterial Agents; Bicarbonates; Fluid Therapy; Gastroenteritis; Glucose; Humans; | 1987 |
[Various compensatory and adaptive changes in the exocrine function of the pancreas in chronic primary gastroduodenitis].
Topics: Adaptation, Physiological; Adolescent; Adult; Bicarbonates; Chronic Disease; Duodenitis; Female; Gas | 1987 |
Fluid therapy in infants and children with acute gastroenteritis and dehydration.
Topics: Acute Disease; Bicarbonates; Child, Preschool; Dehydration; Female; Gastroenteritis; Humans; Infant; | 1974 |
Significance of milk pH in newborn infants.
Topics: Alkalies; Animals; Bicarbonates; Body Weight; Breast Feeding; Escherichia coli; Feces; Gastroenterit | 1972 |
Gastroenteritis of infancy.
Topics: Anti-Bacterial Agents; Bicarbonates; Chlorides; Dehydration; Diet; Escherichia coli Infections; Gast | 1973 |
The homeostatic function of the colon in acute gastroenteritis.
Topics: Acute Disease; Aldosterone; Bicarbonates; Child, Preschool; Colon; Diarrhea; Feces; Gastroenteritis; | 1972 |
Oral rehydration in gastroenteritis in children.
Topics: Administration, Oral; Bicarbonates; Child, Preschool; Female; Gastroenteritis; Glucose; Humans; Infa | 1973 |
Acid-base balance of cerebrospinal fluid in acute uncompensated metabolic acidosis of infancy.
Topics: Acid-Base Equilibrium; Acidosis; Adult; Bicarbonates; Carbon Dioxide; Coma; Gastroenteritis; Humans; | 1974 |
[Metabolic effect of tromethamine in children].
Topics: Acidosis; Acidosis, Renal Tubular; Acidosis, Respiratory; Acute Disease; Asphyxia Neonatorum; Bicarb | 1970 |
Electrolyte changes during the first six days of hospitalization of Bantu male infants with gastro-enteritis.
Topics: Bicarbonates; Black People; Body Weight; Chlorides; Diet Therapy; Gastroenteritis; Hospitalization; | 1970 |
Hypernatraemia in diarrhoeal infants in Lagos.
Topics: Bicarbonates; Blood Urea Nitrogen; Cerebrospinal Fluid Proteins; Child, Preschool; Chlorides; Dehydr | 1970 |
[Significance of metabolic acidosis during severe infections in young children].
Topics: Acid-Base Equilibrium; Acidosis; Acute Disease; Bicarbonates; Carbon Dioxide; Female; Gastroenteriti | 1969 |
Iatrogenic alkalosis in childhood.
Topics: Alkalosis; Bicarbonates; Child, Preschool; Female; Gastroenteritis; Humans; Hypernatremia; Iatrogeni | 1965 |
Acid-base changes in cerebrospinal fluid of infants with metabolic acidosis.
Topics: Acid-Base Equilibrium; Acidosis; Bicarbonates; Blood; Cerebrospinal Fluid; Gastroenteritis; Humans; | 1966 |
Dehydration in acute gastro-enteritis.
Topics: Acidosis; Bicarbonates; Child, Preschool; Dehydration; Diarrhea, Infantile; Gastroenteritis; Humans; | 1966 |