Page last updated: 2024-10-18

hydrogen carbonate and Fatigue

hydrogen carbonate has been researched along with Fatigue in 28 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.

Research Excerpts

ExcerptRelevanceReference
"Eight horses exercised to fatigue were used to characterize the resulting changes in blood pH, in blood lactate, free fatty acid, bicarbonate, and ammonia concentrations, and in muscle glycogen concentrations."3.67Changes in equine metabolic characteristics due to exercise fatigue. ( Lawrence, LM; Miller, PA, 1986)
"Plasma acidosis was not associated with the decline of PPO in a supramaximal trial with elite cyclists."3.30Plasma Acidosis and Peak Power after a Supramaximal Trial in Elite Sprint and Endurance Cyclists: Effect of Bicarbonate. ( Cairns, SP; Lindinger, MI; Maunder, ED; Mildenhall, MJ; Plews, DJ, 2023)
"Time to fatigue was not significantly different between conditions and averaged 263."2.69Acute L-glutamine ingestion does not improve maximal effort exercise. ( Haub, MD; Nau, KL; Potteiger, JA; Webster, MJ; Zebas, CJ, 1998)
"Incidences of arrhythmia, muscular cramps and headache were significantly less frequent during HF."2.68On-line predilution hemofiltration versus ultrapure high-flux hemodialysis: a multicenter prospective study in 23 patients. Sardinian Collaborative Study Group of On-Line Hemofiltration. ( Altieri, P; Asproni, E; Bolasco, F; Bolasco, PG; Bostrom, M; Cabiddu, GF; Cadinu, F; Casu, D; Cossu, M; Ferrara, R; Ganadu, M; Passaghe, M; Pinna, M; Sorba, GB, 1997)
" The subjects performed six 60-s cycling bouts, at a work rate corresponding to 125% VO2 max, with 60 s recovery between work bouts; these regimens were performed 1 h after the ingestion of a solution containing either; I, placebo; II, NaHCO3 in a dosage of 0."2.66Maximal work production following two levels of artificially induced metabolic alkalosis. ( Coutts, KD; Hoeben, HH; Kuzara, G; McKenzie, DC; Stirling, DR, 1986)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199016 (57.14)18.7374
1990's4 (14.29)18.2507
2000's1 (3.57)29.6817
2010's6 (21.43)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Mildenhall, MJ1
Maunder, ED1
Plews, DJ1
Lindinger, MI1
Cairns, SP1
Gough, LA1
Rimmer, S1
Osler, CJ1
Higgins, MF1
Siegler, JC1
Marshall, PW1
Raftry, S1
Brooks, C1
Dowswell, B1
Romero, R1
Green, S1
Mitchell, JB1
Rogers, MM1
Basset, JT1
Hubing, KA1
Chung, F1
Abdullah, HR1
Liao, P1
Bellinger, PM1
Minahan, CL1
Zabala, M1
Peinado, AB1
Calderón, FJ1
Sampedro, J1
Castillo, MJ1
Benito, PJ1
Tailor, P1
Raman, T1
Garganta, CL1
Njalsson, R1
Carlsson, K1
Ristoff, E1
Carey, HB1
Shimizu, AG1
Taylor, DW1
Sackett, DL1
Smith, EK1
Barnes, CC1
Hoda, P1
Lennox, G1
Martin, J1
McNeaney, H1
Mukherjee, J1
Wagner, L1
Schindler, B1
Marhoffer, W1
van Eyl, O1
Strauch, M1
Lefebvre, A1
Mainwood, GW3
Cechetto, D1
Altieri, P1
Sorba, GB1
Bolasco, PG1
Bostrom, M1
Asproni, E1
Ferrara, R1
Bolasco, F1
Cossu, M1
Cadinu, F1
Cabiddu, GF1
Casu, D1
Ganadu, M1
Passaghe, M1
Pinna, M1
Haub, MD1
Potteiger, JA1
Nau, KL1
Webster, MJ1
Zebas, CJ1
Nagai, K1
Pagel, M1
Rattazzi, T1
Vizzo, J1
Scribner, BH2
Graefe, U1
Milutinovich, J1
Follette, WC1
Babb, AL1
Gaitanos, GC1
Nevill, ME1
Brooks, S1
Williams, C1
Grassi, M1
Fraioli, A1
Messina, B1
Mammucari, S1
Mennuni, G1
Lavender, G1
Bird, SR1
Whipp, BJ1
Ward, SA1
Wasserman, K1
McKenzie, DC1
Coutts, KD1
Stirling, DR1
Hoeben, HH1
Kuzara, G1
Miller, PA1
Lawrence, LM1
Binnewies, SM1
Poulus, AJ1
Docter, HJ1
Westra, HG1
Worsley-Brown, P1
Paterson, RA1
Lucier, GE1
De Fabanis, E1
Riccardino, N1
Barcroft, H1
Youlten, LJ1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sleepiness and Tiredness Among Doctors Working In A Tertiary Hospital: Is it Work Related or Is There Underlying Sleep Disorders[NCT04020991]203 participants (Actual)Observational2018-10-01Completed
Efficiency of Speech Therapy in Resistant Hypertensive Patients With Mild Obstructive Sleep Apnea Syndrome[NCT03753633]50 participants (Anticipated)Interventional2017-10-01Active, not recruiting
Investigating the Effects of Wearing Compression Stockings to Improve Asthma Symptoms at Night[NCT03303586]40 participants (Anticipated)Interventional2017-02-21Recruiting
Piloting an Adaption of Cognitive Behavioral Therapy for Insomnia for Shift Workers (CBTI-Shift)[NCT05965609]60 participants (Anticipated)Interventional2023-12-08Recruiting
Impact of Dexmedetomidine Supplemented Analgesia on Sleep Quality in Patients at High-risk of Obstructive Sleep Apnea After Major Surgery: A Randomized, Double-blind, and Placebo-controlled Pilot Study[NCT04608331]Phase 4152 participants (Actual)Interventional2021-01-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for hydrogen carbonate and Fatigue

ArticleYear
Mineral waters in treatment of metabolic changes from fatigue in sportsmen.
    The Journal of sports medicine and physical fitness, 1990, Volume: 30, Issue:4

    Topics: Bicarbonates; Body Water; Electrolytes; Fatigue; Humans; Mineral Waters; Physical Exertion; Sports

1990
Respiratory markers of the anaerobic threshold.
    Advances in cardiology, 1986, Volume: 35

    Topics: Adenosine Triphosphate; Anaerobiosis; Bicarbonates; Cardiovascular Physiological Phenomena; Citric A

1986
[On problems of biochemical changes during muscle activity].
    Zeitschrift fur die gesamte Hygiene und ihre Grenzgebiete, 1968, Volume: 14, Issue:9

    Topics: Adenine Nucleotides; Bicarbonates; Blood Proteins; Carbohydrate Metabolism; Creatine Kinase; Electro

1968

Trials

9 trials available for hydrogen carbonate and Fatigue

ArticleYear
Plasma Acidosis and Peak Power after a Supramaximal Trial in Elite Sprint and Endurance Cyclists: Effect of Bicarbonate.
    Medicine and science in sports and exercise, 2023, 05-01, Volume: 55, Issue:5

    Topics: Acidosis; Bicarbonates; Bicycling; Fatigue; Humans; Lactic Acid; Oxygen; Oxygen Consumption; Physica

2023
The differential effect of metabolic alkalosis on maximum force and rate of force development during repeated, high-intensity cycling.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, Volume: 115, Issue:11

    Topics: Adult; Alkalosis; Bicarbonates; Exercise; Fatigue; Female; Humans; Hydrogen-Ion Concentration; Isome

2013
Bicarbonate ingestion has no ergogenic effect on consecutive all out sprint tests in BMX elite cyclists.
    European journal of applied physiology, 2011, Volume: 111, Issue:12

    Topics: Acid-Base Equilibrium; Adult; Alkalosis; Bicarbonates; Bicycling; Cross-Over Studies; Exercise; Exer

2011
Reducing patient morbidity from high-efficiency hemodialysis: a double-blind crossover trial.
    Transactions - American Society for Artificial Internal Organs, 1983, Volume: 29

    Topics: Acetates; Acetic Acid; Adolescent; Adult; Bicarbonates; Blood Pressure; Fatigue; Headache; Humans; K

1983
On-line predilution hemofiltration versus ultrapure high-flux hemodialysis: a multicenter prospective study in 23 patients. Sardinian Collaborative Study Group of On-Line Hemofiltration.
    Blood purification, 1997, Volume: 15, Issue:3

    Topics: Aged; Arrhythmias, Cardiac; beta 2-Microglobulin; Bicarbonates; Body Weight; Electrolytes; Fatigue;

1997
Acute L-glutamine ingestion does not improve maximal effort exercise.
    The Journal of sports medicine and physical fitness, 1998, Volume: 38, Issue:3

    Topics: Acid-Base Equilibrium; Adult; Bicarbonates; Cross-Over Studies; Double-Blind Method; Exercise Test;

1998
Repeated bouts of sprint running after induced alkalosis.
    Journal of sports sciences, 1991,Winter, Volume: 9, Issue:4

    Topics: Adult; Alkalosis; Bicarbonates; Exercise Test; Fatigue; Heart Rate; Humans; Hydrogen-Ion Concentrati

1991
Effect of sodium bicarbonate ingestion upon repeated sprints.
    British journal of sports medicine, 1989, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Bicarbonates; Fatigue; Female; Humans; Male; Pilot Projects; Running

1989
Maximal work production following two levels of artificially induced metabolic alkalosis.
    Journal of sports sciences, 1986,Spring, Volume: 4, Issue:1

    Topics: Adult; Alkalosis; Bicarbonates; Energy Metabolism; Fatigue; Humans; Hydrogen-Ion Concentration; Male

1986

Other Studies

16 other studies available for hydrogen carbonate and Fatigue

ArticleYear
Ingestion of Sodium Bicarbonate (NaHCO
    International journal of sport nutrition and exercise metabolism, 2017, Volume: 27, Issue:5

    Topics: Acid-Base Equilibrium; Adult; Alkalosis; Bicarbonates; Bicycling; Double-Blind Method; Eating; Exerc

2017
Fatigue during high-intensity endurance exercise: the interaction between metabolic factors and thermal stress.
    Journal of strength and conditioning research, 2014, Volume: 28, Issue:7

    Topics: Adult; Bicarbonates; Body Temperature; Cold Temperature; Exercise Test; Fatigue; Hot Temperature; Hu

2014
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
Metabolic consequences of β-alanine supplementation during exhaustive supramaximal cycling and 4000-m time-trial performance.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2016, Volume: 41, Issue:8

    Topics: Adolescent; Adult; beta-Alanine; Bicarbonates; Bicycling; Body Mass Index; Dietary Supplements; Fati

2016
Recurrent high anion gap metabolic acidosis secondary to 5-oxoproline (pyroglutamic acid).
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 46, Issue:1

    Topics: Acetaminophen; Acid-Base Equilibrium; Acidosis; Amino Acid Metabolism, Inborn Errors; Anorexia; Bica

2005
Side effects in bicarbonate dialysis due to low dialysate pH.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1983, Volume: 19

    Topics: Bicarbonates; Carbon Dioxide; Fatigue; Humans; Hydrogen-Ion Concentration; Muscle Cramp; Renal Dialy

1983
[A hemodialysis bath with bicarbonate improves comfort and ultrafiltration].
    Nephrologie, 1983, Volume: 4, Issue:4-5

    Topics: Acetates; Bicarbonates; Body Weight; Drug Tolerance; Fatigue; Headache; Humans; Nausea; Renal Dialys

1983
The effect of bicarbonate concentration on fatigue and recovery in isolated rat diaphragm muscle.
    Canadian journal of physiology and pharmacology, 1980, Volume: 58, Issue:6

    Topics: Adenosine Triphosphate; Animals; Bicarbonates; Diaphragm; Fatigue; Hydrogen-Ion Concentration; In Vi

1980
The influence of acetate versus bicarbonate on patient symptomatology during dialysis.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1979, Volume: 16

    Topics: Acetates; Adult; Aged; Bicarbonates; Carbon Dioxide; Dialysis; Dizziness; Fatigue; Female; Headache;

1979
Improved tolerance to rapid ultrafiltration with the use of bicarbonate in dialysate.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1977, Volume: 14

    Topics: Acetates; Acid-Base Imbalance; Bicarbonates; Blood Pressure; Fatigue; Humans; Osmolar Concentration;

1977
Changes in equine metabolic characteristics due to exercise fatigue.
    American journal of veterinary research, 1986, Volume: 47, Issue:10

    Topics: Ammonia; Animals; Bicarbonates; Fatigue; Fatty Acids, Nonesterified; Female; Glycogen; Heart Rate; H

1986
Acid-base balance and subjective feelings of fatigue during physical exercise.
    European journal of applied physiology and occupational physiology, 1974, Volume: 33, Issue:3

    Topics: Acid-Base Equilibrium; Adolescent; Adult; Bicarbonates; Blood Pressure; Carbon Dioxide; Fatigue; Hea

1974
The metabolic changes in frog sartorius muscles during recovery from fatigue at different external bicarbonate concentrations.
    Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Anura; Bicarbonates

1972
Fatigue and recovery in isolated frog sartorius muscles: the effects of bicarbonate concentration and associated potassium loss.
    Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:2

    Topics: Animals; Anura; Bicarbonates; Carbon Isotopes; Cell Membrane Permeability; Electric Stimulation; Fat

1972
[Pre and postoperative acid-base balance in maxillary neoplasms].
    Minerva stomatologica, 1967, Volume: 16, Issue:9

    Topics: Acid-Base Equilibrium; Adult; Aged; Anuria; Bicarbonates; Chlorides; Fatigue; Female; Humans; Male;

1967
The effect of tiring the forearm muscles in different ways on venous blood pH, pco2 and standard bicarbonate.
    The Journal of physiology, 1966, Volume: 187, Issue:2

    Topics: Bicarbonates; Blood Circulation; Carbon Dioxide; Fatigue; Forearm; Humans; Hydrogen-Ion Concentratio

1966