hydrogen carbonate has been researched along with Drug Overdose in 13 studies
Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin-associated lactic acidosis (MALA) carries a high mortality rate." | 7.96 | Metformin-associated lactic acidosis: reinforcing learning points. ( Creagh, F; Goonoo, MS; Morris, R; Raithatha, A, 2020) |
| "Metformin-associated lactic acidosis is a rare and serious complication of biguanide treatment." | 7.75 | Metformin-associated lactic acidosis: a prognostic and therapeutic study. ( Fourrier, F; Houdret, N; Nseir, S; Seidowsky, A, 2009) |
| "Clinicians should be aware of the complications of rhabdomyolysis in patients who ingest doxylamine succinate and other over-the-counter antihistamines." | 7.68 | Severe rhabdomyolysis after doxylamine overdose. ( Miller, CH; Ognibere, AJ; Soto, LF, 1993) |
| "Bupropion cardiotoxicity widens QRS complexes by inhibiting cardiac gap junctions." | 4.31 | Sodium bicarbonate treatment for QRS widening in bupropion overdoses. ( Goldfine, C; Johnson, L; Simpson, M, 2023) |
| "Metformin-associated lactic acidosis (MALA) carries a high mortality rate." | 3.96 | Metformin-associated lactic acidosis: reinforcing learning points. ( Creagh, F; Goonoo, MS; Morris, R; Raithatha, A, 2020) |
| "Metformin-associated lactic acidosis is a rare and serious complication of biguanide treatment." | 3.75 | Metformin-associated lactic acidosis: a prognostic and therapeutic study. ( Fourrier, F; Houdret, N; Nseir, S; Seidowsky, A, 2009) |
| "Clinicians should be aware of the complications of rhabdomyolysis in patients who ingest doxylamine succinate and other over-the-counter antihistamines." | 3.68 | Severe rhabdomyolysis after doxylamine overdose. ( Miller, CH; Ognibere, AJ; Soto, LF, 1993) |
| "This is a report of an intentionally administered overdose of dimenhydrinate to a 4 month-old infant who subsequently presented with status epilepticus, coma, and life threatening ventricular dysrhythmias." | 3.68 | Response of life threatening dimenhydrinate intoxication to sodium bicarbonate administration. ( Farrell, M; Heinrichs, M; Tilelli, JA, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (69.23) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Isoardi, KZ | 1 |
| Chiew, AL | 1 |
| Simpson, M | 1 |
| Johnson, L | 1 |
| Goldfine, C | 1 |
| Goonoo, MS | 1 |
| Morris, R | 1 |
| Raithatha, A | 1 |
| Creagh, F | 1 |
| Seidowsky, A | 1 |
| Nseir, S | 1 |
| Houdret, N | 1 |
| Fourrier, F | 1 |
| Soto, LF | 1 |
| Miller, CH | 1 |
| Ognibere, AJ | 1 |
| Heaney, D | 1 |
| Majid, A | 1 |
| Junor, B | 1 |
| Probst, BD | 1 |
| Cetta, F | 1 |
| Wrenn, K | 1 |
| Smith, BA | 1 |
| Slovis, CM | 1 |
| Szerlip, HM | 1 |
| Heeger, P | 1 |
| Feldman, GM | 1 |
| Bernard, S | 1 |
| Farrell, M | 1 |
| Heinrichs, M | 1 |
| Tilelli, JA | 1 |
| Burkhart, KK | 1 |
| Kulig, KW | 1 |
| Hammond, KB | 1 |
| Pearson, JR | 1 |
| Ambruso, D | 1 |
| Rumack, B | 1 |
| Köppel, C | 1 |
| Oberdisse, U | 1 |
| Heinemeyer, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Metformin Overdose in Adult Patients Treated at the University Hospital of Nancy: Single-center Descriptive Retrospective Observational Study[NCT04762966] | 50 participants (Anticipated) | Observational | 2021-03-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 other studies available for hydrogen carbonate and Drug Overdose
| Article | Year |
|---|---|
Too much of a good thing: Bicarbonate toxicity following treatment of sodium channel blocker overdose.
Topics: Bicarbonates; Drug Overdose; Humans; Sodium Channel Blockers | 2022 |
Sodium bicarbonate treatment for QRS widening in bupropion overdoses.
Topics: Adult; Bicarbonates; Bupropion; Cardiotoxicity; Drug Overdose; Electrocardiography; Female; Humans; | 2023 |
Metformin-associated lactic acidosis: reinforcing learning points.
Topics: Acidosis, Lactic; Acute Kidney Injury; Bicarbonates; Continuous Renal Replacement Therapy; Diabetes | 2020 |
Metformin-associated lactic acidosis: a prognostic and therapeutic study.
Topics: Acidosis, Lactic; Adolescent; Adult; Aged; Aged, 80 and over; Bicarbonates; Buffers; Cohort Studies; | 2009 |
Severe rhabdomyolysis after doxylamine overdose.
Topics: Adult; Bicarbonates; Creatine Kinase; Doxylamine; Drug Overdose; Epilepsy, Tonic-Clonic; Histamine H | 1993 |
Bicarbonate haemodialysis as a treatment of metformin overdose.
Topics: Acidosis, Lactic; Adult; Bicarbonates; Buffers; Drug Overdose; Humans; Hypoglycemic Agents; Lactic A | 1997 |
The utility of a 12-lead electrocardiogram in diagnosing a suspected antidepressant overdose.
Topics: Adolescent; Bicarbonates; Desipramine; Drug Overdose; Electrocardiography; Emergency Service, Hospit | 1992 |
Profound alkalemia during treatment of tricyclic antidepressant overdose: a potential hazard of combined hyperventilation and intravenous bicarbonate.
Topics: Adult; Aged; Alkalosis; Antidepressive Agents, Tricyclic; Bicarbonates; Critical Care; Doxepin; Drug | 1992 |
Comparison between acetate and bicarbonate dialysis for the treatment of lithium intoxication.
Topics: Acetates; Adult; Bicarbonates; Drug Overdose; Humans; Lithium Carbonate; Male; Renal Dialysis | 1992 |
Severe lactic acidosis following theophylline overdose.
Topics: Acidosis, Lactic; Adult; Bicarbonates; Charcoal; Coma; Drug Overdose; Emergencies; Female; Glasgow C | 1991 |
Response of life threatening dimenhydrinate intoxication to sodium bicarbonate administration.
Topics: Arrhythmias, Cardiac; Bicarbonates; Child Abuse; Dimenhydrinate; Drug Overdose; Gas Chromatography-M | 1991 |
The rise in the total iron-binding capacity after iron overdose.
Topics: Adult; Bicarbonates; Blood Glucose; Carrier Proteins; Drug Overdose; Ferritins; Humans; Iron; Lactof | 1991 |
Clinical course and outcome in class IC antiarrhythmic overdose.
Topics: Ajmaline; Anti-Arrhythmia Agents; Bicarbonates; Bradycardia; Drug Overdose; Flecainide; Hemoperfusio | 1990 |