hydrogen carbonate has been researched along with Diabetic Nephropathies in 22 studies
Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.
Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We conducted a double-blind, placebo-controlled trial in 81 patients with diabetes, hypertension, and albuminuria (urine albumin-to-creatinine ratio > or =300 mg/g) who all received lisinopril (80 mg once daily)." | 5.14 | Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy. ( Adams-Huet, B; Mehdi, UF; Raskin, P; Toto, RD; Vega, GL, 2009) |
| "2,628 adults with type 2 diabetes and nephropathy." | 2.80 | Serum Bicarbonate and Kidney Disease Progression and Cardiovascular Outcome in Patients With Diabetic Nephropathy: A Post Hoc Analysis of the RENAAL (Reduction of End Points in Non-Insulin-Dependent Diabetes With the Angiotensin II Antagonist Losartan) St ( Bakker, SJ; de Zeeuw, D; Gansevoort, RT; Lambers Heerspink, HJ; Lewis, JB; Lutgers, HL; Schutte, E; Umanath, K; Vart, P; Wolffenbuttel, BH, 2015) |
| "Forty-two chronic renal failure patients-21 DM and 21 NDM-randomly selected among the 97 in our dialysis unit were submitted to an HD session with glucose-free bicarbonate solution (phase 1)." | 2.73 | Glucose-added dialysis fluid prevents asymptomatic hypoglycaemia in regular haemodialysis. ( Burmeister, JE; Campos, BM; da Costa, MG; da Rosa Miltersteiner, D; Scapini, A, 2007) |
| "Peritonitis is the most important complication of continuous ambulatory peritoneal dialysis (CAPD)." | 1.27 | Peritonitis in continuous ambulatory peritoneal dialysis patients. ( Barnes, T; Bower, JD; Hellems, E; Humphries, J; Ray, R; Rubin, J; Teal, N, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (27.27) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 5 (22.73) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Geiger, H | 1 |
| Kaiser, M | 1 |
| Rudolf, S | 1 |
| Büttner, S | 1 |
| Chazot, C | 1 |
| Jean, G | 1 |
| Joly, D | 1 |
| Laustsen, C | 1 |
| Lycke, S | 1 |
| Palm, F | 1 |
| Østergaard, JA | 1 |
| Bibby, BM | 1 |
| Nørregaard, R | 1 |
| Flyvbjerg, A | 1 |
| Pedersen, M | 1 |
| Ardenkjaer-Larsen, JH | 1 |
| Varol, U | 1 |
| Varol, Y | 1 |
| Yaprak, M | 1 |
| Uzum, A | 1 |
| Cirit, M | 1 |
| Schutte, E | 1 |
| Lambers Heerspink, HJ | 1 |
| Lutgers, HL | 1 |
| Bakker, SJ | 1 |
| Vart, P | 1 |
| Wolffenbuttel, BH | 1 |
| Umanath, K | 1 |
| Lewis, JB | 1 |
| de Zeeuw, D | 1 |
| Gansevoort, RT | 1 |
| Pena-Polanco, JE | 1 |
| Fried, LF | 1 |
| Mehdi, UF | 1 |
| Adams-Huet, B | 1 |
| Raskin, P | 1 |
| Vega, GL | 1 |
| Toto, RD | 1 |
| Chauveau, P | 1 |
| Nguyen, H | 1 |
| Combe, C | 1 |
| Chêne, G | 1 |
| Azar, R | 1 |
| Cano, N | 1 |
| Canaud, B | 1 |
| Fouque, D | 1 |
| Laville, M | 1 |
| Leverve, X | 1 |
| Roth, H | 1 |
| Aparicio, M | 1 |
| Burmeister, JE | 1 |
| Scapini, A | 1 |
| da Rosa Miltersteiner, D | 1 |
| da Costa, MG | 1 |
| Campos, BM | 1 |
| Hampl, H | 1 |
| Mahiout, A | 2 |
| Kessel, M | 2 |
| Hampi, H | 1 |
| Rubin, J | 1 |
| Ray, R | 1 |
| Barnes, T | 1 |
| Teal, N | 1 |
| Hellems, E | 1 |
| Humphries, J | 1 |
| Bower, JD | 1 |
| Maeda, K | 1 |
| Kawaguchi, S | 1 |
| Kobayashi, S | 1 |
| Niwa, T | 1 |
| Kobayashi, K | 1 |
| Saito, A | 1 |
| Iyoda, S | 1 |
| Ohta, K | 1 |
| Raja, RM | 1 |
| Lerner, L | 1 |
| Morris, M | 1 |
| Catalano, C | 2 |
| Fabbian, F | 1 |
| Di Landro, D | 1 |
| Verzetti, G | 1 |
| Navino, C | 1 |
| Bolzani, R | 1 |
| Galli, G | 1 |
| Panzetta, G | 1 |
| Mazouz, H | 1 |
| Kacso, I | 1 |
| Ghazali, A | 1 |
| El Esper, N | 1 |
| Moriniere, P | 1 |
| Makdassi, R | 1 |
| Hardy, P | 1 |
| Westeel, PF | 1 |
| Achard, JM | 1 |
| Pruna, A | 1 |
| Fournier, A | 1 |
| Levine, DZ | 1 |
| Iacovitti, M | 1 |
| Burns, KD | 1 |
| Umimoto, K | 1 |
| Hirai, Y | 1 |
| Hayashi, T | 1 |
| Tanaka, H | 1 |
| Woywodt, A | 1 |
| Kielstein, JT | 1 |
| Haller, H | 1 |
| Bank, N | 1 |
| Lahorra, MA | 1 |
| Aynedjian, HS | 1 |
| Enia, G | 1 |
| Zoccali, C | 1 |
| Maggiore, Q | 1 |
| Poon, TF | 1 |
| Ward, MK | 1 |
| Kerr, DN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Tolerance to Hemodialysis in Insulin-Requiring Diabetic Patients: a Prospective Randomized,Cross-over Multicenter Study Between Bicarbonate Dialysis (BD) and Blood Volume Controlled Acetate-Free Biofiltration (BVC-AFB)[NCT01098149] | 55 participants (Actual) | Interventional | 2006-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for hydrogen carbonate and Diabetic Nephropathies
| Article | Year |
|---|---|
[Metabolic complications of chronic kidney disease].
Topics: Acidosis; Aged; Aged, 80 and over; Bicarbonates; Bradycardia; Calcium; Calcium, Dietary; Comorbidity | 2017 |
Established and Emerging Strategies in the Treatment of Chronic Kidney Disease.
Topics: Allopurinol; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bicarbonate | 2016 |
4 trials available for hydrogen carbonate and Diabetic Nephropathies
| Article | Year |
|---|---|
Serum Bicarbonate and Kidney Disease Progression and Cardiovascular Outcome in Patients With Diabetic Nephropathy: A Post Hoc Analysis of the RENAAL (Reduction of End Points in Non-Insulin-Dependent Diabetes With the Angiotensin II Antagonist Losartan) St
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Bicarbonates; Biphenyl Compounds; Diabetes Mel | 2015 |
Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy.
Topics: Adult; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitor | 2009 |
Glucose-added dialysis fluid prevents asymptomatic hypoglycaemia in regular haemodialysis.
Topics: Adult; Aged; Bicarbonates; Circadian Rhythm; Diabetic Nephropathies; Female; Glucose; Hemodialysis S | 2007 |
Acetate-free biofiltration versus bicarbonate haemodialysis in the treatment of patients with diabetic nephropathy: a cross-over multicentric study.
Topics: Acetates; Adult; Aged; Bicarbonates; Cross-Over Studies; Diabetic Nephropathies; Female; Hemodiafilt | 1998 |
16 other studies available for hydrogen carbonate and Diabetic Nephropathies
| Article | Year |
|---|---|
[Therapy of chronic metabolic acidosis among diabetologist].
Topics: Acidosis; Administration, Oral; Bicarbonates; Chronic Disease; Diabetes Mellitus, Type 1; Diabetes M | 2020 |
High altitude may alter oxygen availability and renal metabolism in diabetics as measured by hyperpolarized [1-(13)C]pyruvate magnetic resonance imaging.
Topics: Alanine; Altitude; Altitude Sickness; Animals; Atmospheric Pressure; Bicarbonates; Blood Glucose; Di | 2014 |
Association between hyperlactatemia and occult cardiac failure in diabetic patients on maintenance hemodialysis.
Topics: Aged; Bicarbonates; Blood Gas Analysis; Diabetic Nephropathies; Echocardiography; Female; Heart Fail | 2014 |
Dialyzer membrane permeability and survival in hemodialysis patients.
Topics: Aged; Bicarbonates; Body Composition; Body Mass Index; Cardiovascular Diseases; Cause of Death; Chol | 2005 |
[Pathophysiologic aspects in the treatment of diabetic patients during acetate and bicarbonate dialysis].
Topics: Acetates; Adult; Bicarbonates; Carbon Dioxide; Diabetic Nephropathies; Hemodynamics; Humans; Kidney | 1984 |
Acid base values, hypoxemia in diabetic patients on acetate and bicarbonate dialysis.
Topics: Acetates; Acid-Base Equilibrium; Adult; Bicarbonates; Carbon Dioxide; Diabetic Nephropathies; Humans | 1984 |
Peritonitis in continuous ambulatory peritoneal dialysis patients.
Topics: Bicarbonates; Blood Glucose; Blood Proteins; Diabetic Nephropathies; Family Characteristics; Glomeru | 1983 |
Cell-wash dialysis (CWD).
Topics: Adult; Aged; Bicarbonates; Diabetic Nephropathies; Extracellular Space; Female; Humans; Male; Microc | 1980 |
Hypertension with combined pancreas-kidney transplants in patients with diabetic nephropathy.
Topics: Bicarbonates; Blood Glucose; Blood Pressure; Creatinine; Diabetes Mellitus, Type 1; Diabetic Nephrop | 1993 |
Acute pulmonary oedema occurring in association with diabetic ketoacidosis in a diabetic patient with chronic renal failure.
Topics: Acute Disease; Bicarbonates; Diabetic Ketoacidosis; Diabetic Nephropathies; Humans; Kidney Failure, | 1998 |
Risk factors of renal failure progression two years prior to dialysis.
Topics: Anemia; Bicarbonates; Blood Proteins; Calcium; Cholesterol; Creatinine; Diabetic Nephropathies; Dise | 1999 |
Distal tubule bicarbonate reabsorption in intact and remnant diabetic kidneys.
Topics: Absorption; Acid-Base Equilibrium; Acidosis; Aldosterone; Animals; Bicarbonates; Biological Transpor | 2000 |
The effect of biofiltration on red blood cells 2.3-diphosphoglycerate and pH.
Topics: 2,3-Diphosphoglycerate; Bicarbonates; Cross-Over Studies; Diabetic Nephropathies; Erythrocytes; Hemo | 2000 |
An uncommon cause of metabolic acidosis in a haemodialysis patient.
Topics: Acidosis; Adult; Bicarbonates; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dose-Response Rela | 2002 |
Acute effect of calcium and insulin on hyperfiltration of early diabetes.
Topics: Animals; Bicarbonates; Blood Pressure; Calcium; Carbon Dioxide; Diabetes Mellitus, Experimental; Dia | 1987 |
Hyperchloraemia: a non-specific finding in chronic renal failure.
Topics: Acid-Base Equilibrium; Bicarbonates; Chlorides; Diabetic Nephropathies; Glomerulonephritis; Humans; | 1985 |