hydrogen carbonate has been researched along with Dent Disease in 1 studies
Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.
Dent Disease: X-linked recessive NEPHROLITHIASIS characterized by HYPERCALCIURIA; HYPOPHOSPHATEMIA; NEPHROCALCINOSIS; and PROTEINURIA. It is associated with mutations in the voltage-gated chloride channel, CLC-5 (Dent Disease I). Another group of mutations associated with this disease is in phosphatidylinositol 4,5-bisphosphate-5-phosphatase gene.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mutations of the CLCN5 gene cause Dent disease." | 1.37 | Chloride channel (Clc)-5 is necessary for exocytic trafficking of Na+/H+ exchanger 3 (NHE3). ( Cha, B; Donowitz, M; Duan, X; Guggino, SE; Hubbard, A; Hulamm, P; Jin, S; Lin, Z; Martini, S; Wang, T, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, Z | 1 |
| Jin, S | 1 |
| Duan, X | 1 |
| Wang, T | 1 |
| Martini, S | 1 |
| Hulamm, P | 1 |
| Cha, B | 1 |
| Hubbard, A | 1 |
| Donowitz, M | 1 |
| Guggino, SE | 1 |
1 other study available for hydrogen carbonate and Dent Disease
| Article | Year |
|---|---|
Chloride channel (Clc)-5 is necessary for exocytic trafficking of Na+/H+ exchanger 3 (NHE3).
Topics: Animals; Bicarbonates; Cell Line; Chloride Channels; Dent Disease; Disease Models, Animal; Endocytos | 2011 |