Page last updated: 2024-10-18

hydrogen carbonate and Critical Illness

hydrogen carbonate has been researched along with Critical Illness in 53 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Critical Illness: A disease or state in which death is possible or imminent.

Research Excerpts

ExcerptRelevanceReference
"The sodium bicarbonate for the treatment of severe metabolic acidosis with moderate or severe acute kidney injury in the critically ill: a randomised clinical trial (BICARICU-2) trial is an investigator-initiated, multiple centre, stratified, parallel-group, unblinded trial with a computer-generated allocation sequence and an electronic system-based randomisation."9.69Sodium bicarbonate for the treatment of severe metabolic acidosis with moderate or severe acute kidney injury in the critically ill: protocol for a randomised clinical trial (BICARICU-2). ( Huguet, H; Jaber, S; Jung, B; Molinari, N, 2023)
"L-lactic acidosis (L-LA) is the most common cause of metabolic acidosis in the critical care setting, which has been associated with a large increase in mortality."9.05L-lactic acidosis: pathophysiology, classification, and causes; emphasis on biochemical and metabolic basis. ( Halperin, ML; Kamel, KS; Oh, MS, 2020)
"This article reviews the current body of knowledge regarding lactic acidosis in critically ill patients."8.78Lactic acidosis in critical illness. ( Falk, JL; Mizock, BA, 1992)
"From January 2004 to November 2008, 11 cases of metformin-associated lactic acidosis were seen at a medical center in Taiwan."7.75Impact of acute kidney injury on metformin-associated lactic acidosis. ( Wen, YK, 2009)
"A single dose of acetazolamide effectively corrects metabolic alkalosis in critically ill patients by decreasing the serum SID."7.73Acetazolamide-mediated decrease in strong ion difference accounts for the correction of metabolic alkalosis in critically ill patients. ( Moviat, M; Pickkers, P; van der Hoeven, JG; van der Voort, PH, 2006)
"The sodium bicarbonate for the treatment of severe metabolic acidosis with moderate or severe acute kidney injury in the critically ill: a randomised clinical trial (BICARICU-2) trial is an investigator-initiated, multiple centre, stratified, parallel-group, unblinded trial with a computer-generated allocation sequence and an electronic system-based randomisation."5.69Sodium bicarbonate for the treatment of severe metabolic acidosis with moderate or severe acute kidney injury in the critically ill: protocol for a randomised clinical trial (BICARICU-2). ( Huguet, H; Jaber, S; Jung, B; Molinari, N, 2023)
"Urine alkalinisation with sodium bicarbonate decreases renal oxidative stress and might attenuate sepsisassociated acute kidney injury (s-AKI)."5.17Safety evaluation of a trial of lipocalin-directed sodium bicarbonate infusion for renal protection in at-risk critically ill patients. ( Bellomo, R; Eastwood, GM; Garcia, M; Harley, N; Moore, E; Peck, L; Reade, M; Schneider, AG; Young, H, 2013)
"L-lactic acidosis (L-LA) is the most common cause of metabolic acidosis in the critical care setting, which has been associated with a large increase in mortality."5.05L-lactic acidosis: pathophysiology, classification, and causes; emphasis on biochemical and metabolic basis. ( Halperin, ML; Kamel, KS; Oh, MS, 2020)
"This article reviews the current body of knowledge regarding lactic acidosis in critically ill patients."4.78Lactic acidosis in critical illness. ( Falk, JL; Mizock, BA, 1992)
"From January 2004 to November 2008, 11 cases of metformin-associated lactic acidosis were seen at a medical center in Taiwan."3.75Impact of acute kidney injury on metformin-associated lactic acidosis. ( Wen, YK, 2009)
"A single dose of acetazolamide effectively corrects metabolic alkalosis in critically ill patients by decreasing the serum SID."3.73Acetazolamide-mediated decrease in strong ion difference accounts for the correction of metabolic alkalosis in critically ill patients. ( Moviat, M; Pickkers, P; van der Hoeven, JG; van der Voort, PH, 2006)
"Metabolic alkalosis is characterized by the primary elevation of the serum bicarbonate concentration with a normal or elevated partial pressure of carbon dioxide."2.66Metabolic Alkalosis in the Pediatric Patient: Treatment Options in the Pediatric ICU or Pediatric Cardiothoracic ICU Setting. ( Tobias, JD, 2020)
"Metabolic acidosis is subdivided into anion gap and non-gap acidosis."1.91Acid-Base Disorders in the Critically Ill Patient. ( Achanti, A; Szerlip, HM, 2023)
"Treatment of diabetic ketoacidosis with intravenous insulin is effective but resource intensive."1.91Bicarbonate as a predictor of successful insulin transition in critically ill patients with diabetic ketoacidosis: A retrospective cohort study. ( Aberegg, SK; Gebhart, BC; Pan, RJ; Price, EC; Wolfe, BM, 2023)
"We also modeled predictors of arrhythmias in surgical patients."1.91Arrhythmias in Critically Ill Surgical and Non-surgical Patients: A National Propensity-Matched Study. ( An, SJ; Charles, A; Davis, D; Gallaher, J; Peiffer, S; Tignanelli, CJ, 2023)
"After adjusting for respiratory failure, malignant cancer, anticoagulation, liver disease, white blood cell (WBC), red cell distribution width (RDW), glucose, bicarbonate, and temperature, BUN/Cr had week correlation with the increased risk of in-hospital mortality of cerebral infarction patients (RR = 1."1.72The Association of Blood Urea Nitrogen to Creatinine Ratio and the Prognosis of Critically Ill Patients with Cerebral Infarction: A Cohort Study. ( Chen, T; Gong, Q; Li, AP; Zhao, YX; Zhou, L; Zhou, WS; Zhou, ZW, 2022)
"Cardiogenic shock is a feared complication of acute myocardial infarction with high mortality rates."1.48Baseline serum bicarbonate levels independently predict short-term mortality in critically ill patients with ischaemic cardiogenic shock. ( Berger, D; Bloechlinger, S; Häner, J; Räber, L; Schefold, JC; Wigger, O; Windecker, S; Zanchin, T, 2018)
"Hyperchloremic acidosis is frequent in critically ill patients."1.42Renal tubular acidosis is highly prevalent in critically ill patients. ( Brunner, R; Drolz, A; Fuhrmann, V; Holzinger, U; Scherzer, TM; Schneeweiß, B; Staufer, K; Zauner, C, 2015)
"Shock was more frequently present in the low [BE] group (46% versus 24%, P = 0."1.35Severe hyperlactatemia with normal base excess: a quantitative analysis using conventional and Stewart approaches. ( Dubin, A; Kutscherauer, DO; Masevicius, FD; Pein, MC; Tuhay, G, 2008)
"Fifty-six patients with acute renal failure and continuous venovenous hemofiltration treatment."1.32Effect of filtration volume of continuous venovenous hemofiltration in the treatment of patients with acute renal failure in intensive care units. ( Brause, M; Grabensee, B; Heering, P; Neumann, A; Schumacher, T, 2003)
"We report quadriparesis as a result of severe hypokalaemia and acidosis in a 50-year-old man who had undergone ureterosigmoidostomy for bladder extrophy 48 years earlier."1.31Life-threatening hypokalaemia and quadriparesis in a patient with ureterosigmoidostomy. ( Bac, DJ; De Leeuw, PW; Dees, A; Nienhuis, IE; Van Bekkum, JW, 2002)

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (13.21)18.2507
2000's18 (33.96)29.6817
2010's14 (26.42)24.3611
2020's14 (26.42)2.80

Authors

AuthorsStudies
Lehr, AR1
Rached-d'Astous, S1
Barrowman, N1
Tsampalieros, A1
Parker, M1
McIntyre, L1
Sampson, M1
Menon, K1
Achanti, A1
Szerlip, HM1
Chen, T1
Li, AP1
Gong, Q1
Zhou, L1
Zhao, YX1
Zhou, ZW1
Zhou, WS1
Bendiab, E1
Garnier, F1
Soler, M1
Fosset, M1
Jaber, S2
Molinari, N2
Jung, B2
Price, EC1
Wolfe, BM1
Pan, RJ1
Gebhart, BC1
Aberegg, SK1
An, SJ1
Davis, D1
Peiffer, S1
Gallaher, J1
Tignanelli, CJ1
Charles, A1
Huguet, H1
Bihari, S1
Galluccio, S1
Kamel, KS1
Oh, MS1
Halperin, ML1
Cointault, O1
Tailpied, P1
Mari, A1
Faguer, S1
Tobias, JD1
Brems, JH1
Casey, JD1
Wang, L1
Self, WH1
Rice, TW1
Semler, MW1
Warnar, C1
Faber, E1
Katinakis, PA1
Schermer, T1
Spronk, PE1
Calame, P1
Winiszewski, H1
Doussot, A1
Malakhia, A1
Grillet, F1
Verdot, P1
Vuitton, L1
Ronot, M1
Pili-Floury, S1
Heyd, B1
Delabrousse, E1
Piton, G1
Wigger, O1
Bloechlinger, S1
Berger, D1
Häner, J1
Zanchin, T1
Windecker, S1
Räber, L1
Schefold, JC1
Lumholdt, M1
Damgaard, KA1
Christensen, EF1
Leutscher, PDC1
Schricker, S1
Schanz, M1
Alscher, MD1
Kimmel, M1
Schneider, AG1
Bellomo, R5
Reade, M1
Peck, L1
Young, H1
Eastwood, GM1
Garcia, M1
Moore, E1
Harley, N1
Libório, AB1
Noritomi, DT1
Leite, TT1
de Melo Bezerra, CT1
de Faria, ER1
Kellum, JA1
Brunner, R1
Drolz, A1
Scherzer, TM1
Staufer, K1
Fuhrmann, V1
Zauner, C1
Holzinger, U1
Schneeweiß, B1
Li, Y1
Wang, J1
Bai, Z1
Chen, J1
Wang, X1
Pan, J1
Li, X1
Feng, X1
Varrier, M1
Ostermann, M1
Hynes, D1
Bates, S1
Loughman, A1
Klim, S1
French, C1
Kelly, AM1
Allardet-Servent, J1
Lebsir, M1
Dubroca, C1
Fabrigoule, M1
Jordana, S1
Signouret, T1
Castanier, M1
Thomas, G1
Soundaravelou, R1
Lepidi, A1
Delapierre, L1
Penaranda, G1
Halfon, P1
Seghboyan, JM1
Das, S1
Misra, B1
Roul, L1
Minz, NT1
Pattnaik, M1
Baig, MA1
Wen, YK1
Aman, J1
Nurmohamed, SA1
Vervloet, MG1
Groeneveld, AB1
Surbatovic, M1
Radakovic, S1
Jevtic, M1
Filipovic, N1
Romic, P1
Popovic, N1
Jevdjic, J1
Grujic, K1
Djordjevic, D1
Hetzel, GR1
Schmitz, M1
Wissing, H1
Ries, W1
Schott, G1
Heering, PJ1
Isgro, F1
Kribben, A1
Himmele, R1
Grabensee, B2
Rump, LC1
Herrington, WG1
Nye, HJ1
Hammersley, MS1
Watkinson, PJ1
Christensen, M1
Chen, F1
Barenbrock, M1
Schaefer, RM1
Brause, M1
Neumann, A1
Schumacher, T1
Heering, P1
Eachempati, SR1
Reed, RL1
Barie, PS1
Naka, T1
Martin, MJ1
FitzSullivan, E1
Salim, A1
Berne, TV1
Towfigh, S1
Fuller, HD1
Vriesendorp, TM1
van Santen, S1
DeVries, JH1
de Jonge, E1
Rosendaal, FR1
Schultz, MJ1
Hoekstra, JB1
Moviat, M1
Pickkers, P1
van der Voort, PH1
van der Hoeven, JG1
Story, DA3
Morimatsu, H2
Egi, M1
Tolwani, AJ1
Prendergast, MB1
Speer, RR1
Stofan, BS1
Wille, KM1
Tuhay, G1
Pein, MC1
Masevicius, FD1
Kutscherauer, DO1
Dubin, A1
Fanconi, S1
Burger, R1
Ghelfi, D1
Uehlinger, J1
Arbenz, U1
Jabor, A2
Kazda, A2
Waldau, T1
Larsen, VH1
Bonde, J1
Fogh-Andersen, N1
Thomas, AN1
Guy, JM1
Kishen, R1
Geraghty, IF1
Bowles, BJ1
Vadgama, P1
Kierdorf, HP1
Leue, C1
Arns, S1
Fencl, V1
Figge, J1
Poustie, S1
Van Bekkum, JW1
Bac, DJ1
Nienhuis, IE1
De Leeuw, PW1
Dees, A1
Mizock, BA1
Falk, JL1
Lee, MH1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Renal Tubular Acidosis is Highly Prevalent in Critically Ill Patients[NCT02392091]100 participants (Actual)Observational2011-04-30Completed
Diagnosis Accuracy of Abdominal Compression and Hemoconcentration to Detect Diuretic Induced Fluid Removal Intolerance.[NCT03145935]40 participants (Anticipated)Observational2017-05-10Recruiting
Citrate Versus Heparin Anticoagulation in Continuous Venovenous Hemofiltration in Critically Ill Patients With Acute Renal Failure: A Randomized Clinical Trial[NCT00209378]139 participants (Actual)Interventional2005-05-31Completed
Simplified Regional Citrate Anticoagulation Protocols for CVVH, CVVHDF and SLED Focused on the Prevention of RRT-related Hypophosphatemia and Optimization of Acid-base Balance: a Pilot Study[NCT03976440]30 participants (Anticipated)Observational2019-06-01Active, not recruiting
Effects of Acetazolamide on the Duration of Mechanical Ventilation in Patients With Metabolic Alkalosis. Phase III Multicenter Double-blinded Clinical Trial.[NCT01499485]Phase 3140 participants (Actual)Interventional2011-11-30Completed
A Prospective, Before and After Study of the Impact of Lower Chloride Intravenous Fluid Management on Patients' Acid-base Status, Renal Profile,Length of Stay and Mortality.[NCT00885404]Phase 47,000 participants (Anticipated)Interventional2009-02-28Active, not recruiting
Evaluation of a Simplified Protocol for Regional Citrate Anticoagulation in Continuous Venovenous Hemodiafiltration[NCT00583765]20 participants (Actual)Observational2005-04-30Completed
Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill : A Multiple Center Randomized Clinical Trial (BICAR-ICU)[NCT02476253]Phase 3400 participants (Anticipated)Interventional2015-05-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for hydrogen carbonate and Critical Illness

ArticleYear
Balanced Versus Unbalanced Fluid in Critically Ill Children: Systematic Review and Meta-Analysis.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2022, 03-01, Volume: 23, Issue:3

    Topics: Acute Kidney Injury; Bicarbonates; Child; Critical Illness; Crystalloid Solutions; Female; Fluid The

2022
L-lactic acidosis: pathophysiology, classification, and causes; emphasis on biochemical and metabolic basis.
    Kidney international, 2020, Volume: 97, Issue:1

    Topics: Acidosis, Lactic; Anions; Bicarbonates; Citric Acid Cycle; Critical Illness; Electron Transport Chai

2020
Metabolic Alkalosis in the Pediatric Patient: Treatment Options in the Pediatric ICU or Pediatric Cardiothoracic ICU Setting.
    World journal for pediatric & congenital heart surgery, 2020, Volume: 11, Issue:6

    Topics: Acetazolamide; Alkalosis; Bicarbonates; Carbonic Anhydrase Inhibitors; Child; Critical Illness; Huma

2020
[Metabolic acidosis : Diagnosis and treatment].
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2020, Volume: 115, Issue:4

    Topics: Acid-Base Equilibrium; Acidosis; Bicarbonates; Critical Illness; Humans

2020
Fluid Composition and Clinical Effects.
    Critical care clinics, 2015, Volume: 31, Issue:4

    Topics: Acute Kidney Injury; Albumins; Anaphylaxis; Bicarbonates; Blood Volume; Colloids; Critical Illness;

2015
Bench-to-bedside review: treating acid-base abnormalities in the intensive care unit--the role of renal replacement therapy.
    Critical care (London, England), 2004, Volume: 8, Issue:2

    Topics: Acetates; Acid-Base Imbalance; Bicarbonates; Critical Care; Critical Illness; Hemofiltration; Humans

2004
Lactate- or bicarbonate-buffered solutions in continuous extracorporeal renal replacement therapies.
    Kidney international. Supplement, 1999, Issue:72

    Topics: Acute Kidney Injury; Bicarbonates; Buffers; Critical Illness; Hemodialysis Solutions; Humans; Lactat

1999
Lactic acidosis in critical illness.
    Critical care medicine, 1992, Volume: 20, Issue:1

    Topics: Acidosis, Lactic; Bicarbonates; Blood Gas Analysis; Carbonates; Citric Acid Cycle; Critical Illness;

1992

Trials

8 trials available for hydrogen carbonate and Critical Illness

ArticleYear
Long-Term Outcome of Severe Metabolic Acidemia in ICU Patients, a BICAR-ICU Trial Post Hoc Analysis.
    Critical care medicine, 2023, 01-01, Volume: 51, Issue:1

    Topics: Acidosis; Bicarbonates; Critical Illness; Humans; Intensive Care Units; Quality of Life; Sodium Bica

2023
Sodium bicarbonate for the treatment of severe metabolic acidosis with moderate or severe acute kidney injury in the critically ill: protocol for a randomised clinical trial (BICARICU-2).
    BMJ open, 2023, 08-17, Volume: 13, Issue:8

    Topics: Acute Kidney Injury; Bicarbonates; Critical Illness; Humans; Informed Consent; Randomized Controlled

2023
Safety evaluation of a trial of lipocalin-directed sodium bicarbonate infusion for renal protection in at-risk critically ill patients.
    Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2013, Volume: 15, Issue:2

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Aged; Bicarbonates; Chlorides; Critical Illness; Double-B

2013
Metabolic effects of citrate- vs bicarbonate-based substitution fluid in continuous venovenous hemofiltration: a prospective sequential cohort study.
    Journal of critical care, 2010, Volume: 25, Issue:1

    Topics: Acid-Base Equilibrium; Acute Kidney Injury; Anticoagulants; Bicarbonates; Buffers; Calcium; Citric A

2010
Regional citrate versus systemic heparin for anticoagulation in critically ill patients on continuous venovenous haemofiltration: a prospective randomized multicentre trial.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:1

    Topics: Acute Kidney Injury; Aged; Anticoagulants; Bicarbonates; Buffers; Citrates; Critical Illness; Female

2011
Cardiovascular outcome in critically ill patients treated with continuous haemofiltration--beneficial effects of bicarbonate-buffered replacement fluids.
    EDTNA/ERCA journal (English ed.), 2002, Volume: Suppl 2

    Topics: Acute Kidney Injury; Bicarbonates; Buffers; Cardiovascular Diseases; Creatinine; Critical Illness; D

2002
Hemodynamic effects of sodium bicarbonate in critically ill neonates.
    Intensive care medicine, 1993, Volume: 19, Issue:2

    Topics: Acidosis, Lactic; Bicarbonates; Birth Weight; Blood Gas Analysis; Blood Gas Monitoring, Transcutaneo

1993
Comparison of lactate and bicarbonate buffered haemofiltration fluids: use in critically ill patients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1997, Volume: 12, Issue:6

    Topics: Acidosis; Adult; Bicarbonates; Buffers; Critical Illness; Hemofiltration; Humans; Lactic Acid; Prosp

1997

Other Studies

37 other studies available for hydrogen carbonate and Critical Illness

ArticleYear
Acid-Base Disorders in the Critically Ill Patient.
    Clinical journal of the American Society of Nephrology : CJASN, 2023, 01-01, Volume: 18, Issue:1

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Alkalosis; Bicarbonates; Critical Illness; Hum

2023
The Association of Blood Urea Nitrogen to Creatinine Ratio and the Prognosis of Critically Ill Patients with Cerebral Infarction: A Cohort Study.
    Mediators of inflammation, 2022, Volume: 2022

    Topics: Anticoagulants; Bicarbonates; Blood Urea Nitrogen; Cerebral Infarction; Cohort Studies; Creatinine;

2022
Bicarbonate as a predictor of successful insulin transition in critically ill patients with diabetic ketoacidosis: A retrospective cohort study.
    Pharmacotherapy, 2023, Volume: 43, Issue:6

    Topics: Adult; Bicarbonates; Critical Illness; Diabetes Mellitus; Diabetic Ketoacidosis; Humans; Insulin; Re

2023
Arrhythmias in Critically Ill Surgical and Non-surgical Patients: A National Propensity-Matched Study.
    World journal of surgery, 2023, Volume: 47, Issue:11

    Topics: Albumins; Arrhythmias, Cardiac; Bicarbonates; Cardiovascular Diseases; Critical Illness; Humans; Int

2023
Discrepancy in Chloride Measurement with Decreasing Bicarbonate Concentrations.
    Clinical laboratory, 2019, Aug-01, Volume: 65, Issue:8

    Topics: Bicarbonates; Blood Gas Analysis; Chlorides; Critical Illness; Electrodes; Humans; Hydrogen-Ion Conc

2019
Respiratory Dialysis With Low Bicarbonate Dialysate in Critically Ill Patients: Is Acetate-Free Biofiltration the Answer?
    Critical care medicine, 2020, Volume: 48, Issue:11

    Topics: Bicarbonates; Carbon Dioxide; Critical Illness; Dialysis Solutions; Hemodiafiltration; Humans; Renal

2020
Balanced crystalloids versus saline in critically ill adults with low plasma bicarbonate: A secondary analysis of a clinical trial.
    Journal of critical care, 2021, Volume: 63

    Topics: Adult; Bicarbonates; Critical Illness; Cross-Over Studies; Crystalloid Solutions; Fluid Therapy; Hum

2021
Electrolyte monitoring during regional citrate anticoagulation in continuous renal replacement therapy.
    Journal of clinical monitoring and computing, 2022, Volume: 36, Issue:3

    Topics: Acute Kidney Injury; Anticoagulants; Bicarbonates; Calcium; Citrates; Citric Acid; Continuous Renal

2022
Evaluating the Risk of Irreversible Intestinal Necrosis Among Critically Ill Patients With Nonocclusive Mesenteric Ischemia.
    The American journal of gastroenterology, 2021, 07-01, Volume: 116, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Bicarbonates; Critical Illness; Female; Humans; Intestine, Small; La

2021
Baseline serum bicarbonate levels independently predict short-term mortality in critically ill patients with ischaemic cardiogenic shock.
    European heart journal. Acute cardiovascular care, 2018, Volume: 7, Issue:1

    Topics: Bicarbonates; Biomarkers; Cause of Death; Critical Illness; Female; Hospital Mortality; Humans; Inte

2018
Mathematical arterialisation of peripheral venous blood gas for obtainment of arterial blood gas values: a methodological validation study in the clinical setting.
    Journal of clinical monitoring and computing, 2019, Volume: 33, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Arteries; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Critical

2019
Increased serum bicarbonate in critically ill patients: a retrospective analysis.
    Intensive care medicine, 2015, Volume: 41, Issue:3

    Topics: Aged; Bicarbonates; Biomarkers; Blood Gas Analysis; Critical Illness; Female; Hospital Mortality; Hu

2015
Renal tubular acidosis is highly prevalent in critically ill patients.
    Critical care (London, England), 2015, Apr-06, Volume: 19

    Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Renal Tubular; Adult; Aged; Bicarbonates; Chlorides; Crit

2015
Early fluid overload is associated with acute kidney injury and PICU mortality in critically ill children.
    European journal of pediatrics, 2016, Volume: 175, Issue:1

    Topics: Acute Kidney Injury; Bicarbonates; Child, Preschool; Critical Illness; Female; Humans; Infant; Inten

2016
Arteriovenous blood gas agreement in intensive care patients with varying levels of circulatory compromise: a pilot study.
    Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2015, Volume: 17, Issue:4

    Topics: Aged; Arteries; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Cohort Studies; Critical Care; Cri

2015
Point-of-Care Versus Central Laboratory Measurements of Hemoglobin, Hematocrit, Glucose, Bicarbonate and Electrolytes: A Prospective Observational Study in Critically Ill Patients.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Bicarbonates; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; C

2017
Insulin resistance and beta cell function as prognostic indicator in multi-organ dysfunction syndrome.
    Metabolic syndrome and related disorders, 2009, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Aged; APACHE; Bicarbonates; Blood Glucose; Critical Illness; Disease Progression;

2009
Impact of acute kidney injury on metformin-associated lactic acidosis.
    International urology and nephrology, 2009, Volume: 41, Issue:4

    Topics: Academic Medical Centers; Acidosis, Lactic; Acute Kidney Injury; Aged; Anti-Bacterial Agents; Bicarb

2009
Predictive value of serum bicarbonate, arterial base deficit/excess and SAPS III score in critically ill patients.
    General physiology and biophysics, 2009, Volume: 28 Spec No

    Topics: APACHE; Arteries; Bicarbonates; Critical Illness; Female; Humans; Hydrogen-Ion Concentration; Male;

2009
Are arterial and venous samples clinically equivalent for the estimation of pH, serum bicarbonate and potassium concentration in critically ill patients?
    Diabetic medicine : a journal of the British Diabetic Association, 2012, Volume: 29, Issue:1

    Topics: Acid-Base Imbalance; Arteries; Bicarbonates; Blood Gas Analysis; Critical Illness; Diabetic Ketoacid

2012
Advanced arterial blood gas analysis in septic shock: a Singaporean nursing case review.
    Intensive & critical care nursing, 2013, Volume: 29, Issue:2

    Topics: Acid-Base Equilibrium; Bicarbonates; Blood Gas Analysis; Critical Care Nursing; Critical Illness; De

2013
Effect of filtration volume of continuous venovenous hemofiltration in the treatment of patients with acute renal failure in intensive care units.
    Critical care medicine, 2003, Volume: 31, Issue:3

    Topics: Acidosis; Acute Kidney Injury; Aged; APACHE; Bicarbonates; Blood Urea Nitrogen; Blood Volume; Body W

2003
Serum bicarbonate concentration correlates with arterial base deficit in critically ill patients.
    Surgical infections, 2003,Summer, Volume: 4, Issue:2

    Topics: Acid-Base Imbalance; Bicarbonates; Blood Gas Analysis; Cohort Studies; Critical Care; Critical Illne

2003
Use of serum bicarbonate measurement in place of arterial base deficit in the surgical intensive care unit.
    Archives of surgery (Chicago, Ill. : 1960), 2005, Volume: 140, Issue:8

    Topics: Acidosis; Adult; Aged; Bicarbonates; Biomarkers; Blood Gas Analysis; Cohort Studies; Critical Care;

2005
The contribution of blood chemistry to the electrical resistance of blood: an in vitro model.
    Acta physiologica Hungarica, 2005, Volume: 92, Issue:2

    Topics: Adult; Aged; Bicarbonates; Blood Chemical Analysis; Blood Glucose; Blood Proteins; Cardiac Output; C

2005
Predisposing factors for hypoglycemia in the intensive care unit.
    Critical care medicine, 2006, Volume: 34, Issue:1

    Topics: Adult; Age Distribution; Aged; Bicarbonates; Blood Glucose; Causality; Cohort Studies; Confidence In

2006
Acetazolamide-mediated decrease in strong ion difference accounts for the correction of metabolic alkalosis in critically ill patients.
    Critical care (London, England), 2006, Volume: 10, Issue:1

    Topics: Acetazolamide; Acid-Base Imbalance; Adult; Aged; Alkalosis; Bicarbonates; Critical Illness; Female;

2006
Hyperchloremic acidosis in the critically ill: one of the strong-ion acidoses?
    Anesthesia and analgesia, 2006, Volume: 103, Issue:1

    Topics: Acid-Base Equilibrium; Acidosis; Bicarbonates; Chlorides; Critical Illness; Humans

2006
The effect of albumin concentration on plasma sodium and chloride measurements in critically ill patients.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:4

    Topics: Bicarbonates; Blood Chemical Analysis; Chlorides; Critical Illness; Humans; Hypoalbuminemia; Intensi

2007
A practical citrate anticoagulation continuous venovenous hemodiafiltration protocol for metabolic control and high solute clearance.
    Clinical journal of the American Society of Nephrology : CJASN, 2006, Volume: 1, Issue:1

    Topics: Acid-Base Equilibrium; Acute Kidney Injury; Anticoagulants; Bicarbonates; Citrates; Clinical Protoco

2006
Severe hyperlactatemia with normal base excess: a quantitative analysis using conventional and Stewart approaches.
    Critical care (London, England), 2008, Volume: 12, Issue:3

    Topics: Acid-Base Equilibrium; Acidosis, Lactic; Aged; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Chl

2008
Modelling of acid-base equilibria.
    Acta anaesthesiologica Scandinavica. Supplementum, 1995, Volume: 107

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Acidosis, Lactic; Algorithms; Alkalosis; Anion

1995
Lactate, pH, and blood gas analysis in critically ill patients.
    Acta anaesthesiologica Scandinavica. Supplementum, 1995, Volume: 107

    Topics: Acid-Base Imbalance; Adult; Aged; Bacterial Infections; Bicarbonates; Carbon Dioxide; Critical Illne

1995
Diagnosis of metabolic acid-base disturbances in critically ill patients.
    American journal of respiratory and critical care medicine, 2000, Volume: 162, Issue:6

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Adult; Arteries; Bicarbonates; Carbon Dioxide; Critical

2000
Comparison of three methods to estimate plasma bicarbonate in critically ill patients: Henderson-Hasselbalch, enzymatic, and strong-ion-gap.
    Anaesthesia and intensive care, 2001, Volume: 29, Issue:6

    Topics: Acid-Base Imbalance; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Critical Illness; Humans; Hyd

2001
Life-threatening hypokalaemia and quadriparesis in a patient with ureterosigmoidostomy.
    The Netherlands journal of medicine, 2002, Volume: 60, Issue:1

    Topics: Acidosis, Renal Tubular; Anastomosis, Surgical; Bicarbonates; Bladder Exstrophy; Chlorides; Colon, S

2002
Gastric mucosal pH as a prognostic index of mortality in critically ill patients.
    Critical care medicine, 1992, Volume: 20, Issue:7

    Topics: Bicarbonates; Critical Illness; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Prognosis

1992