Page last updated: 2024-10-18

hydrogen carbonate and Colonic Neoplasms

hydrogen carbonate has been researched along with Colonic Neoplasms in 14 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
"In MDA-MB-231 breast cancer cells expressing high levels of SLC4A4 compared to LS174 cells, SLC4A4 knockdown had a strong impact on cell proliferation, migration, and invasion."1.42The Na(+)/HCO3(-) Co-Transporter SLC4A4 Plays a Role in Growth and Migration of Colon and Breast Cancer Cells. ( Parks, SK; Pouyssegur, J, 2015)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's6 (42.86)18.2507
2000's4 (28.57)29.6817
2010's1 (7.14)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Chang, HW1
Frey, G1
Liu, H1
Xing, C1
Steinman, L1
Boyle, WJ1
Short, JM1
Parks, SK1
Pouyssegur, J1
Swietach, P1
Patiar, S1
Supuran, CT1
Harris, AL1
Vaughan-Jones, RD1
Höglund, P1
Busche, R1
Bartels, J1
von Engelhardt, W1
Köttgen, M1
Leipziger, J1
Fischer, KG1
Nitschke, R1
Greger, R2
Dagher, PC1
Morton, TZ1
Joo, CS1
Taglietta-Kohlbrecher, A1
Egnor, RW1
Charney, AN1
Bischof, G1
Cosentini, E2
Hamilton, G2
Riegler, M1
Zacherl, J1
Teleky, B2
Feil, W1
Schiessel, R1
Machen, TE1
Wenzl, E2
Ushikubi, F1
Sugimoto, Y1
Ichikawa, A1
Narumiya, S1
Haberl, I1
Pertschy, P1
Mallinger, R1
Baumgartner, G1
Davies, RJ1
Asbun, H1
Thompson, SM1
Goller, DA1
Sandle, GI1
Kunzelmann, K1
Gerlach, L1
Fröbe, U1
Wilpart, M1
Roberfroid, M1
Leffall, LD1

Reviews

1 review available for hydrogen carbonate and Colonic Neoplasms

ArticleYear
Roles of prostanoids revealed from studies using mice lacking specific prostanoid receptors.
    Japanese journal of pharmacology, 2000, Volume: 83, Issue:4

    Topics: Animals; Asthma; Bicarbonates; Colonic Neoplasms; Dinoprost; Dinoprostone; Female; Fever; Hypertensi

2000

Other Studies

13 other studies available for hydrogen carbonate and Colonic Neoplasms

ArticleYear
Generating tumor-selective conditionally active biologic anti-CTLA4 antibodies via protein-associated chemical switches.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 03-02, Volume: 118, Issue:9

    Topics: 5'-Nucleotidase; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neo

2021
The Na(+)/HCO3(-) Co-Transporter SLC4A4 Plays a Role in Growth and Migration of Colon and Breast Cancer Cells.
    Journal of cellular physiology, 2015, Volume: 230, Issue:8

    Topics: Bicarbonates; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Colonic Neoplasm

2015
The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths.
    The Journal of biological chemistry, 2009, Jul-24, Volume: 284, Issue:30

    Topics: Acids; Antigens, Neoplasm; Bicarbonates; Carbon Dioxide; Carbonic Anhydrase IX; Carbonic Anhydrases;

2009
SLC26A3 and congenital chloride diarrhoea.
    Novartis Foundation symposium, 2006, Volume: 273

    Topics: Antiporters; Bicarbonates; Chloride-Bicarbonate Antiporters; Chlorides; Colonic Neoplasms; Diarrhea;

2006
Regulation of intracellular pH in the colonic epithelial cell line HT29 clone 19A.
    DTW. Deutsche tierarztliche Wochenschrift, 1995, Volume: 102, Issue:4

    Topics: Antiporters; Bicarbonates; Chloride-Bicarbonate Antiporters; Chlorides; Colon; Colonic Neoplasms; Ep

1995
pH regulation in HT29 colon carcinoma cells.
    Pflugers Archiv : European journal of physiology, 1994, Volume: 428, Issue:2

    Topics: Acid-Base Equilibrium; Antiporters; Bicarbonates; Chloride-Bicarbonate Antiporters; Chlorides; Colon

1994
Modulation of secretagogue-induced chloride secretion by intracellular bicarbonate.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 1

    Topics: Analysis of Variance; Animals; Bicarbonates; Bucladesine; Carbachol; Cell Line; Chlorides; Colon; Co

1994
Effects of extracellular pH on intracellular pH-regulation and growth in a human colon carcinoma cell-line.
    Biochimica et biophysica acta, 1996, Jun-13, Volume: 1282, Issue:1

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Bicarbonates; Carbon Dioxide; Carrier P

1996
The differentiation inducers phenylacetate and phenylbutyrate modulate camptothecin sensitivity in colon carcinoma cells in vitro by intracellular acidification.
    International journal of oncology, 2001, Volume: 19, Issue:5

    Topics: Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Bicarbonates; Camptothecin; Cell Cycle; Ce

2001
Uncoupling of sodium chloride transport in premalignant mouse colon.
    Gastroenterology, 1990, Volume: 98, Issue:6

    Topics: 1,2-Dimethylhydrazine; Action Potentials; Animals; Bicarbonates; Carcinogens; Chlorides; Colonic Neo

1990
Bicarbonate permeability of epithelial chloride channels.
    Pflugers Archiv : European journal of physiology, 1991, Volume: 417, Issue:6

    Topics: Bicarbonates; Cell Membrane Permeability; Chlorides; Colonic Neoplasms; Electric Conductivity; Epith

1991
Intestinal carcinogenesis and dietary fibers: the influence of cellulose or Fybogel chronically given after exposure to DMH.
    Nutrition and cancer, 1987, Volume: 10, Issue:1-2

    Topics: 1,2-Dimethylhydrazine; Animals; Bicarbonates; Body Weight; Cellulose; Citrates; Citric Acid; Colonic

1987
Trends in the diagnosis and management of polyps and cancer of the colon and rectum.
    The American surgeon, 1972, Volume: 38, Issue:3

    Topics: Adenoma; Barium Sulfate; Bicarbonates; Blood Pressure; Central Venous Pressure; Colonic Neoplasms; F

1972