hydrogen carbonate has been researched along with Cancer of Liver in 19 studies
Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chemotherapy for liver metastasis of breast cancer has rarely been found effective." | 5.28 | [Clinical efficacy of ifosfamide for liver metastasis of breast cancer]. ( Ando, K; Funahashi, H; Imai, T; Kato, M; Kato, N; Narita, T; Odaka, K; Oike, E; Ono, M; Sato, Y, 1990) |
| "Surgery is the main treatment for liver cancer, but the most common liver cancer – called hepatocellular carcinoma – can sometimes become too large to remove safely." | 2.82 | A nonrandomized cohort and a randomized study of local control of large hepatocarcinoma by targeting intratumoral lactic acidosis. ( Chao, M; Hu, X; Jin, K; Li, B; Wu, H; Wu, J; Yang, G; Zhang, G, 2016) |
| "The Barcelona-Clinic Liver Cancer (BCLC) stage was also an important prognostic factor; the median survival times for BCLC stages A, B and C were 251, 175 and 40 d, respectively (P < 0." | 1.42 | Prognostic factors of spontaneously ruptured hepatocellular carcinoma. ( Han, XJ; Shao, HB; Su, HY; Xu, K, 2015) |
| "Lactic acidosis is the result of imbalance between the systemic formation of lactate and its hepatic metabolism." | 1.40 | Warburg's effect on solid tumors. ( El Imad, T; El Khoury, L; Geara, AS, 2014) |
| "To study the biochemical profile in hepatocellular carcinoma patients." | 1.29 | Biochemical profile in liver cancer patients. ( Iqtidar, A; Rasheed, A, 1995) |
| "Chemotherapy for liver metastasis of breast cancer has rarely been found effective." | 1.28 | [Clinical efficacy of ifosfamide for liver metastasis of breast cancer]. ( Ando, K; Funahashi, H; Imai, T; Kato, M; Kato, N; Narita, T; Odaka, K; Oike, E; Ono, M; Sato, Y, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (52.63) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (21.05) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Berz, AM | 1 |
| Santana, JG | 1 |
| Iseke, S | 1 |
| Gross, M | 1 |
| Pekurovsky, V | 1 |
| Laage Gaupp, F | 1 |
| Savic, LJ | 1 |
| Borde, T | 1 |
| Gottwald, LA | 1 |
| Boustani, AM | 1 |
| Gebauer, B | 1 |
| Lin, M | 1 |
| Zhang, X | 1 |
| Schlachter, T | 1 |
| Madoff, DC | 1 |
| Chapiro, J | 1 |
| Ying, C | 1 |
| Jin, C | 1 |
| Zeng, S | 1 |
| Chao, M | 2 |
| Hu, X | 2 |
| El Imad, T | 1 |
| El Khoury, L | 1 |
| Geara, AS | 1 |
| Han, XJ | 1 |
| Su, HY | 1 |
| Shao, HB | 1 |
| Xu, K | 1 |
| Wu, H | 1 |
| Jin, K | 1 |
| Li, B | 1 |
| Wu, J | 1 |
| Zhang, G | 1 |
| Yang, G | 1 |
| Goldwasser, P | 1 |
| Manjappa, NG | 1 |
| Luhrs, CA | 1 |
| Barth, RH | 1 |
| Wahl, RL | 1 |
| Ziessman, HA | 1 |
| Juni, J | 1 |
| Lahti, D | 1 |
| Fields, AL | 1 |
| Wolman, SL | 1 |
| Halperin, ML | 1 |
| Colman, LK | 1 |
| Baker, TM | 1 |
| Jähde, E | 1 |
| Rajewsky, MF | 1 |
| Rasheed, A | 1 |
| Iqtidar, A | 1 |
| Mori, M | 1 |
| Tatibana, M | 1 |
| Matsuno, T | 1 |
| Funahashi, H | 1 |
| Sato, Y | 1 |
| Imai, T | 1 |
| Kato, N | 1 |
| Ando, K | 1 |
| Oike, E | 1 |
| Odaka, K | 1 |
| Ono, M | 1 |
| Narita, T | 1 |
| Kato, M | 1 |
| Gullino, PM | 1 |
| Grantham, FH | 1 |
| Smith, SH | 1 |
| Haggerty, AC | 1 |
| Mayfield, ED | 1 |
| Lyman, K | 1 |
| Bresnick, E | 1 |
| Van Rossum, GD | 1 |
| Gosalvez, M | 1 |
| Galeotti, T | 1 |
| Morris, HP | 1 |
| Iwanami, Y | 1 |
| Inose, M | 1 |
| Perret, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Trial of the Efficacy of Hepatectomy or TILA-TACE in Patients With Resectable Hepatocellular Carcinoma[NCT03314532] | 230 participants (Anticipated) | Interventional | 2017-11-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for hydrogen carbonate and Cancer of Liver
| Article | Year |
|---|---|
A nonrandomized cohort and a randomized study of local control of large hepatocarcinoma by targeting intratumoral lactic acidosis.
Topics: Acidosis, Lactic; Adult; Aged; Aged, 80 and over; Bicarbonates; Carcinoma; Chemoembolization, Therap | 2016 |
18 other studies available for hydrogen carbonate and Cancer of Liver
| Article | Year |
|---|---|
Impact of Chemoembolic Regimen on Immune Cell Recruitment and Immune Checkpoint Marker Expression following Transcatheter Arterial Chemoembolization in a VX2 Rabbit Liver Tumor Model.
Topics: Animals; Antibiotics, Antineoplastic; Bicarbonates; Carcinoma, Hepatocellular; Chemoembolization, Th | 2022 |
Alkalization of cellular pH leads to cancer cell death by disrupting autophagy and mitochondrial function.
Topics: Acidosis, Lactic; Autophagy; Bicarbonates; Carcinoma, Hepatocellular; Cell Death; Chemoembolization, | 2022 |
Warburg's effect on solid tumors.
Topics: Acidosis, Lactic; Acute Kidney Injury; Administration, Intravenous; Aged; Bicarbonates; Disease Prog | 2014 |
Prognostic factors of spontaneously ruptured hepatocellular carcinoma.
Topics: Adult; Age Factors; Aged; Alanine Transaminase; Bicarbonates; Biomarkers, Tumor; Carcinoma, Hepatoce | 2015 |
Pseudohypobicarbonatemia caused by an endogenous assay interferent: a new entity.
Topics: Acid-Base Equilibrium; Acidosis; Aged; Artifacts; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; | 2011 |
Gastric air contrast: useful adjunct to hepatic artery scintigraphy.
Topics: Bicarbonates; Carbon Dioxide; Citrates; Citric Acid; Drug Combinations; Hepatic Artery; Humans; Infu | 1984 |
Chronic lactic acidosis in a patient with cancer: therapy and metabolic consequences.
Topics: Acidosis; Bicarbonates; Cachexia; Dichloroacetic Acid; Glycolysis; Humans; Lactates; Liver Neoplasms | 1981 |
Lactic acidosis with extensive oat cell carcinoma of the lung--not necessarily a poor prognostic sign: case report.
Topics: Acidosis; Antineoplastic Agents; Bicarbonates; Carcinoma, Small Cell; Humans; Lactates; Liver Neopla | 1983 |
Tumor-selective modification of cellular microenvironment in vivo: effect of glucose infusion on the pH in normal and malignant rat tissues.
Topics: Animals; Bicarbonates; Blood Glucose; Brain; Glucose; Glycolysis; Hydrogen-Ion Concentration; Hyperg | 1982 |
Biochemical profile in liver cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bicarbonates; Blood Urea Nitrogen; Carc | 1995 |
Glutaminase activity of glutamine-dependent carbamoyl-phosphate synthase from rat ascites hepatoma. Regulation by adenosine triphosphate-magensium and magnesium ion.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Ammonium Chloride; Animals; Bicarbonates; Carbamo | 1977 |
Pathway of glutamate oxidation and its regulation in the HuH13 line of human hepatoma cells.
Topics: Alanine Transaminase; Aminooxyacetic Acid; Aspartate Aminotransferases; Bicarbonates; Carcinoma, Hep | 1991 |
[Clinical efficacy of ifosfamide for liver metastasis of breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bicarbonates; Breast Neoplasms; Doxorubicin; Drug Ad | 1990 |
Modifications of the acid-base status of the internal milieu of tumors.
Topics: Acid-Base Equilibrium; Ammonium Chloride; Animals; Bicarbonates; Blood Chemical Analysis; Body Fluid | 1965 |
Incorporation of bicarbonate-14 C into pyrimidines and into ribonucleic acid of the Novikoff ascites tumor cell.
Topics: Ammonia; Animals; Aspartic Acid; Bicarbonates; Carcinoma, Hepatocellular; Chromatography, Ion Exchan | 1967 |
Net movements of monovalent and bivalent cations, and their relation to energy metabolism, in slices of hepatoma 3924A and of a mammary tumour.
Topics: Adenosine Triphosphate; Animals; Benz(a)Anthracenes; Bicarbonates; Biological Transport; Calcium; Ca | 1971 |
Transfer-RNA methylase activity in rat ascites hepatomas: Altered methylation patterns in the presence of guanidine carbonate.
Topics: Animals; Bicarbonates; Carbon Radioisotopes; Carbonates; Carcinoma, Hepatocellular; Escherichia coli | 1974 |
[Lactic acidosis].
Topics: Acidosis; Adolescent; Adult; Aged; Bicarbonates; Diabetic Ketoacidosis; Female; Glucose; Humans; Lac | 1970 |