hydrogen carbonate has been researched along with CKD-MBD in 25 studies
Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This article reviews the clinical, biological, radiological, and pathological procedures and their respective indications for the practical diagnosis of the following various histological patterns of renal osteodystrophy: osteitis fibrosa due to parathyroid hormone (PTH) hypersecretion: osteomalacia or rickets due to native vitamin D deficiency and/or aluminum overload; and adynamic bone disease (ABD) due to aluminum overload and/or PTH secretion oversuppression." | 4.80 | Renal osteodystrophy in dialysis patients: diagnosis and treatment. ( Abighanem, O; Achard, JM; Atik, A; Boudailliez, B; El Esper, N; Fournier, A; Ghazali, A; Hedri, H; Hottelart, C; Moriniere, P; Oprisiu, R; Pruna, A; Rasolombololona, M; Said, S; Sarraj, A; Sechet, A; Westeel, PF; Yverneau, PH, 1998) |
| "Metabolic acidosis is noted in the majority of patients with chronic kidney disease (CKD) when glomerular filtration rate (GFR) decreases to less than 20% to 25% of normal, although as many as 20% of individuals can have acid-base parameters close to or within the normal range." | 2.43 | Metabolic acidosis of CKD: diagnosis, clinical characteristics, and treatment. ( Kraut, JA; Kurtz, I, 2005) |
| "Renal osteodystrophy is a state of impaired bone quality and strength." | 1.91 | Comprehensive Associations between Acidosis and the Skeleton in Patients with Kidney Disease. ( Agarwal, S; Aponte, MA; Brown, DD; Dempster, D; Fusaro, M; Guo, XE; Kamanda-Kosseh, M; Kumar, J; Levy, RV; McMahon, DJ; Melamed, ML; Misof, BM; Nickolas, TL; Reidy, K; Zhou, H, 2023) |
| " No significant difference in 1-alpha-OH-D3 dosage or serum 1,25(OH)2D3 was found between the genders in the study period." | 1.29 | Changes in bone mineral content during long-term CAPD. Indication of a sex-dependent bone mineral loss. ( Lyhne, N; Pedersen, FB, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (52.00) | 18.7374 |
| 1990's | 5 (20.00) | 18.2507 |
| 2000's | 3 (12.00) | 29.6817 |
| 2010's | 3 (12.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Levy, RV | 1 |
| McMahon, DJ | 1 |
| Agarwal, S | 1 |
| Dempster, D | 1 |
| Zhou, H | 1 |
| Misof, BM | 1 |
| Guo, XE | 1 |
| Kamanda-Kosseh, M | 1 |
| Aponte, MA | 1 |
| Reidy, K | 1 |
| Kumar, J | 1 |
| Fusaro, M | 1 |
| Brown, DD | 1 |
| Melamed, ML | 2 |
| Nickolas, TL | 1 |
| Seras, M | 1 |
| Martín de Francisco, ÁL | 1 |
| Piñera, C | 1 |
| Gundin, S | 1 |
| García-Unzueta, M | 1 |
| Kislikova, M | 1 |
| Albines, Z | 1 |
| Serrano, M | 1 |
| Arias, M | 1 |
| Buttar, RS | 1 |
| Coco, M | 1 |
| De Paola, L | 1 |
| Coppolino, G | 1 |
| Bolignano, D | 1 |
| Buemi, M | 1 |
| Lombardi, L | 1 |
| London, GM | 1 |
| Marty, C | 1 |
| Marchais, SJ | 1 |
| Guerin, AP | 1 |
| Metivier, F | 1 |
| de Vernejoul, MC | 2 |
| Kraut, JA | 1 |
| Kurtz, I | 1 |
| Brewster, UC | 1 |
| Ciampi, MA | 1 |
| Abu-Alfa, AK | 1 |
| Reilly, RF | 1 |
| Chan, JC | 1 |
| Lyhne, N | 1 |
| Pedersen, FB | 1 |
| Wilske, J | 1 |
| Attman, PO | 1 |
| Fournier, A | 1 |
| Oprisiu, R | 1 |
| Hottelart, C | 1 |
| Yverneau, PH | 1 |
| Ghazali, A | 1 |
| Atik, A | 1 |
| Hedri, H | 1 |
| Said, S | 1 |
| Sechet, A | 1 |
| Rasolombololona, M | 1 |
| Abighanem, O | 1 |
| Sarraj, A | 1 |
| El Esper, N | 1 |
| Moriniere, P | 1 |
| Boudailliez, B | 1 |
| Westeel, PF | 1 |
| Achard, JM | 1 |
| Pruna, A | 1 |
| Fuchs, C | 1 |
| Brasche, M | 1 |
| Donath-Wolfram, U | 1 |
| Kubosch, J | 1 |
| Quellhorst, E | 1 |
| Scheler, F | 1 |
| Duursma, SA | 1 |
| Dorhout Mees, EJ | 1 |
| Hutchison, AJ | 1 |
| Freemont, AJ | 1 |
| Boulton, HF | 1 |
| Gokal, R | 1 |
| Kanagawa, S | 1 |
| Yosikawa, Y | 1 |
| Dohi, Y | 1 |
| Lefebvre, A | 1 |
| Gueris, J | 1 |
| Goldfarb, B | 1 |
| Graulet, AM | 1 |
| Morieux, C | 1 |
| Kleeman, CR | 1 |
| Better, OS | 1 |
| Cordy, PE | 1 |
| Gagnon, R | 1 |
| Taves, DR | 1 |
| Kaye, M | 1 |
| Ingham, JP | 1 |
| Kleerekoper, M | 1 |
| Stewart, JH | 1 |
| Posen, S | 1 |
| Cohn, SH | 1 |
| Cinque, TJ | 1 |
| Dombrowski, CS | 1 |
| Letteri, JM | 1 |
| Bishop, MC | 1 |
| Ledingham, JG | 1 |
| Stickler, GB | 1 |
| Bergen, BJ | 1 |
| Artemenko, SP | 1 |
| Matsuda, I | 1 |
| Takeda, T | 1 |
| Sugai, M | 1 |
| Matsuura, N | 1 |
| Stanbury, SW | 1 |
| Lumb, GA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Nicotinamide and Sevelamer Hydrochloride on Phosphatemia Control on Chronic Hemodialysed Patients[NCT01011699] | Phase 3 | 176 participants (Actual) | Interventional | 2010-01-31 | Terminated (stopped due to Financial problem) | ||
| Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill : A Multiple Center Randomized Clinical Trial (BICAR-ICU)[NCT02476253] | Phase 3 | 400 participants (Anticipated) | Interventional | 2015-05-05 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for hydrogen carbonate and CKD-MBD
| Article | Year |
|---|---|
CKD-Mineral Bone Disorder in Stage 4 and 5 CKD: What We Know Today?
Topics: Bicarbonates; Chelating Agents; Chronic Kidney Disease-Mineral and Bone Disorder; Cinacalcet; Diet, | 2016 |
Metabolic acidosis of CKD: diagnosis, clinical characteristics, and treatment.
Topics: Acidosis; beta 2-Microglobulin; Bicarbonates; Cardiovascular Diseases; Chronic Disease; Chronic Kidn | 2005 |
Renal osteodystrophy in dialysis patients: diagnosis and treatment.
Topics: Adult; Alkaline Phosphatase; Aluminum; Bicarbonates; Biopsy; Calcifediol; Calcium; Calcium Carbonate | 1998 |
Disordered divalent ion metabolism in kidney disease: comments on pathogenesis and treatment.
Topics: Bicarbonates; Bone Resorption; Calcium; Cholecalciferol; Chronic Kidney Disease-Mineral and Bone Dis | 1973 |
[A case of Butler-Albright syndrome].
Topics: Acidosis, Renal Tubular; Adolescent; Bicarbonates; Calcium; Chlorides; Chronic Kidney Disease-Minera | 1970 |
3 trials available for hydrogen carbonate and CKD-MBD
| Article | Year |
|---|---|
Haemodialysis session: the perfect storm for vascular calcification.
Topics: Acid-Base Imbalance; Aged; Aged, 80 and over; Bicarbonates; Calcium; Chronic Kidney Disease-Mineral | 2015 |
Low-calcium dialysis fluid and oral calcium carbonate in CAPD. A method of controlling hyperphosphataemia whilst minimizing aluminium exposure and hypercalcaemia.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aluminum; Bicarbonates; Bone and Bones; Calcium; Calc | 1992 |
Optimal correction of acidosis changes progression of dialysis osteodystrophy.
Topics: Acidosis; Bicarbonates; Biopsy; Bone and Bones; Chronic Kidney Disease-Mineral and Bone Disorder; Di | 1989 |
17 other studies available for hydrogen carbonate and CKD-MBD
| Article | Year |
|---|---|
Comprehensive Associations between Acidosis and the Skeleton in Patients with Kidney Disease.
Topics: Acidosis; Bicarbonates; Bone Density; Chronic Kidney Disease-Mineral and Bone Disorder; Cross-Sectio | 2023 |
Parathyroid hormone variability parameters for identifying high turnover osteodystrophy disease in hemodialysis patients: an observational retrospective cohort study.
Topics: Aged; Bicarbonates; Biomarkers; Chronic Kidney Disease-Mineral and Bone Disorder; Cohort Studies; Fe | 2010 |
Arterial calcifications and bone histomorphometry in end-stage renal disease.
Topics: Aluminum; Bicarbonates; Bone and Bones; Bone Density; Calcium; Calcium Phosphates; Chronic Kidney Di | 2004 |
Long-term comparison of sevelamer hydrochloride to calcium-containing phosphate binders.
Topics: Acetates; Bicarbonates; Calcium; Calcium Carbonate; Calcium Compounds; Chronic Kidney Disease-Minera | 2006 |
Fluid-electrolyte and acid-base disorders in children.
Topics: Acid-Base Imbalance; Acidosis, Renal Tubular; Acute Kidney Injury; Bicarbonates; Calcium Metabolism | 1981 |
Changes in bone mineral content during long-term CAPD. Indication of a sex-dependent bone mineral loss.
Topics: Adult; Aged; Alkaline Phosphatase; Bicarbonates; Bone Density; Calcium; Chronic Kidney Disease-Miner | 1995 |
Increase of calcitriol during treatment with protein-reduced diet in patients with renal failure.
Topics: Adult; Aged; Bicarbonates; Body Mass Index; Calcifediol; Calcitriol; Calcium; Chronic Kidney Disease | 1994 |
Dailysate calcium and plasma calcium fractions during and after haemodialysis.
Topics: Bicarbonates; Blood Proteins; Calcium; Carbon Dioxide; Chronic Kidney Disease-Mineral and Bone Disor | 1975 |
[Treatment of renal osteodystrophy].
Topics: Alkaline Phosphatase; Bicarbonates; Calcium; Chronic Kidney Disease-Mineral and Bone Disorder; Dihyd | 1978 |
[Phosphate binders for therapy of hyperphosphatemia causing secondary hyperparathyroidism and renal osteodystrophy in patients with chronic renal failure].
Topics: Acetates; Acetic Acid; Allantoin; Aluminum Hydroxide; Bicarbonates; Chronic Kidney Disease-Mineral a | 1991 |
Bone disease in hemodialysis patients with particular reference to the effect of fluoride.
Topics: Adult; Alkaline Phosphatase; Bicarbonates; Blood Urea Nitrogen; Bone Resorption; Calcium; Chronic Ki | 1974 |
Symptomatic skeletal disease in non-terminal renal failure.
Topics: Adult; Aged; Alkaline Phosphatase; Analgesics; Bicarbonates; Bone Diseases; Calcium; Chronic Kidney | 1974 |
Determination of body composition by neutron activation analysis in patient with renal failure.
Topics: Activation Analysis; Adult; Bicarbonates; Blood Urea Nitrogen; Body Composition; Calcium; Chronic Ki | 1972 |
Alkali treatment of renal osteodystrophy.
Topics: Acidosis; Alkaline Phosphatase; Bicarbonates; Bone Development; Child, Preschool; Chronic Kidney Dis | 1972 |
A review: short stature in renal disease.
Topics: Acidosis, Renal Tubular; Adolescent; Adult; Age Factors; Alkaline Phosphatase; Bicarbonates; Blood U | 1973 |
Oculocerebrorenal syndrome in a child with a normal urinary acidification and a defect in bicarbonate reabsorption.
Topics: Acidosis, Renal Tubular; Ammonium Chloride; Bicarbonates; Cataract; Child; Chronic Kidney Disease-Mi | 1969 |
Parathyroid function in chronic renal failure. A statistical survey of the plasma biochemistry in azotaemic renal osteodystrophy.
Topics: Bicarbonates; Blood Proteins; Blood Urea Nitrogen; Calcium; Chronic Kidney Disease-Mineral and Bone | 1966 |