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hydrogen carbonate and Breast Cancer

hydrogen carbonate has been researched along with Breast Cancer in 12 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Research Excerpts

ExcerptRelevanceReference
"Chemotherapy for liver metastasis of breast cancer has rarely been found effective."5.28[Clinical efficacy of ifosfamide for liver metastasis of breast cancer]. ( Ando, K; Funahashi, H; Imai, T; Kato, M; Kato, N; Narita, T; Odaka, K; Oike, E; Ono, M; Sato, Y, 1990)
" In this study, we prepared nanoscaled RBCs (RAs) containing oxyHb and gas-generating agent ammonium bicarbonate (ABC) for co-loading and controlled release of ICG and DOX, thus hoping to achieve synergistic effects of PTT/PDT and chemotherapy against breast cancer."3.88Nanoscaled red blood cells facilitate breast cancer treatment by combining photothermal/photodynamic therapy and chemotherapy. ( Chen, B; Li, L; Shi, S; Wan, G; Wang, D; Wang, Y; Zhang, L; Zhang, T, 2018)
"In MDA-MB-231 breast cancer cells expressing high levels of SLC4A4 compared to LS174 cells, SLC4A4 knockdown had a strong impact on cell proliferation, migration, and invasion."1.42The Na(+)/HCO3(-) Co-Transporter SLC4A4 Plays a Role in Growth and Migration of Colon and Breast Cancer Cells. ( Parks, SK; Pouyssegur, J, 2015)
"Using our mouse model for metastatic breast cancer (MDA-MB-231), we designed an interventional survival study where tumor bearing mice received bicarbonate, DCA, or DCA-bicarbonate (DB) therapies chronically."1.37Bicarbonate and dichloroacetate: evaluating pH altering therapies in a mouse model for metastatic breast cancer. ( Martin, NK; Robey, IF, 2011)
"Chemotherapy for liver metastasis of breast cancer has rarely been found effective."1.28[Clinical efficacy of ifosfamide for liver metastasis of breast cancer]. ( Ando, K; Funahashi, H; Imai, T; Kato, M; Kato, N; Narita, T; Odaka, K; Oike, E; Ono, M; Sato, Y, 1990)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's3 (25.00)18.2507
2000's2 (16.67)29.6817
2010's4 (33.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Park, JM1
Reed, GD1
Liticker, J1
Putnam, WC1
Chandra, A1
Yaros, K1
Afzal, A1
MacNamara, J1
Raza, J1
Hall, RG1
Baxter, J1
Derner, K1
Pena, S1
Kallem, RR1
Subramaniyan, I1
Edpuganti, V1
Harrison, CE1
Muthukumar, A1
Lewis, C1
Reddy, S1
Unni, N1
Klemow, D1
Syed, S1
Li, H1
Cole, S1
Froehlich, T1
Ayers, C1
de Lemos, J1
Malloy, CR1
Haley, B1
Zaha, VG1
Wan, G1
Chen, B1
Li, L1
Wang, D1
Shi, S1
Zhang, T1
Wang, Y2
Zhang, L1
Parks, SK1
Pouyssegur, J1
Xia, J1
Feng, G1
Xia, X1
Hao, L1
Wang, Z1
Robey, IF1
Martin, NK1
Sennoune, SR1
Bakunts, K1
Martínez, GM2
Chua-Tuan, JL1
Kebir, Y1
Attaya, MN1
Martínez-Zaguilán, R2
Lee, AH1
Tannock, IF1
Raghunand, N1
Lynch, RM1
Bellamy, W1
Rojas, B1
Smith, D1
Dalton, WS1
Gillies, RJ1
Nicholl, AJ1
Killey, J1
Leonard, MN1
Garner, C1
Funahashi, H1
Sato, Y1
Imai, T1
Kato, N1
Ando, K1
Oike, E1
Odaka, K1
Ono, M1
Narita, T1
Kato, M1
Krarup-Hansen, A1
Wassermann, K1
Rasmussen, SN1
Dalmark, M1
Bondy, PK1

Other Studies

12 other studies available for hydrogen carbonate and Breast Cancer

ArticleYear
Effect of Doxorubicin on Myocardial Bicarbonate Production From Pyruvate Dehydrogenase in Women With Breast Cancer.
    Circulation research, 2020, 12-04, Volume: 127, Issue:12

    Topics: Adult; Antibiotics, Antineoplastic; Bicarbonates; Breast Neoplasms; Carbon-13 Magnetic Resonance Spe

2020
Nanoscaled red blood cells facilitate breast cancer treatment by combining photothermal/photodynamic therapy and chemotherapy.
    Biomaterials, 2018, Volume: 155

    Topics: Animals; Apoptosis; Bicarbonates; Breast Neoplasms; Cell Line, Tumor; Doxorubicin; Erythrocytes; Fem

2018
The Na(+)/HCO3(-) Co-Transporter SLC4A4 Plays a Role in Growth and Migration of Colon and Breast Cancer Cells.
    Journal of cellular physiology, 2015, Volume: 230, Issue:8

    Topics: Bicarbonates; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Colonic Neoplasm

2015
NH
    International journal of nanomedicine, 2017, Volume: 12

    Topics: Animals; Bicarbonates; Breast Neoplasms; Cell Line, Tumor; Diagnostic Imaging; Female; Humans; Lipos

2017
Bicarbonate and dichloroacetate: evaluating pH altering therapies in a mouse model for metastatic breast cancer.
    BMC cancer, 2011, Jun-10, Volume: 11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Bicarbonates; Breast Neoplasms; Cell Hypoxia;

2011
Vacuolar H+-ATPase in human breast cancer cells with distinct metastatic potential: distribution and functional activity.
    American journal of physiology. Cell physiology, 2004, Volume: 286, Issue:6

    Topics: Acid-Base Equilibrium; Bicarbonates; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Membrane; C

2004
Heterogeneity of intracellular pH and of mechanisms that regulate intracellular pH in populations of cultured cells.
    Cancer research, 1998, May-01, Volume: 58, Issue:9

    Topics: Amiloride; Animals; Antiporters; Bicarbonates; Breast Neoplasms; Chloride-Bicarbonate Antiporters; C

1998
pH and drug resistance. I. Functional expression of plasmalemmal V-type H+-ATPase in drug-resistant human breast carcinoma cell lines.
    Biochemical pharmacology, 1999, May-01, Volume: 57, Issue:9

    Topics: Antineoplastic Agents; Benzopyrans; Bicarbonates; Biological Transport; Breast Neoplasms; Cell Compa

1999
The role of bicarbonate in regulatory volume decrease (RVD) in the epithelial-derived human breast cancer cell line ZR-75-1.
    Pflugers Archiv : European journal of physiology, 2002, Volume: 443, Issue:5-6

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Antineoplastic Agents, Hormonal; Bicarbonates; Bre

2002
[Clinical efficacy of ifosfamide for liver metastasis of breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:4 Pt 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bicarbonates; Breast Neoplasms; Doxorubicin; Drug Ad

1990
Pharmacokinetics of doxorubicin in man with induced acid or alkaline urine.
    Acta oncologica (Stockholm, Sweden), 1988, Volume: 27, Issue:1

    Topics: Acid-Base Equilibrium; Adult; Bicarbonates; Breast Neoplasms; Diarrhea; Doxorubicin; Female; Humans;

1988
Some 'pseudo' and some true endocrine syndromes in cancer.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:1

    Topics: Adrenocorticotropic Hormone; Alkalosis; Bicarbonates; Breast Neoplasms; Calcium; Carcinoma, Bronchog

1974