hydrogen carbonate has been researched along with Bone Loss, Osteoclastic in 42 studies
Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Urinary excretion of calcium and bone resorption marker N-terminal telopeptide of type I collagen was reduced by 12 and 8%, respectively (calcium, P = 0." | 2.77 | Alkaline salts to counteract bone resorption and protein wasting induced by high salt intake: results of a randomized controlled trial. ( Biolo, G; Buehlmeier, J; Frings-Meuthen, P; Heer, M; Maser-Gluth, C; Remer, T; Stehle, P, 2012) |
| "Bicarbonate or alkali diet decreases bone resorption in humans." | 2.74 | Alkaline mineral water lowers bone resorption even in calcium sufficiency: alkaline mineral water and bone metabolism. ( Aeschlimann, JM; Burckhardt, P; Krieg, MA; Wynn, E, 2009) |
| "Both salts significantly lowered the bone resorption marker NTX (P < 0." | 2.52 | The effect of supplementation with alkaline potassium salts on bone metabolism: a meta-analysis. ( Burckhardt, P; Frassetto, L; Gannon, R; Lambert, H; Lanham-New, S; Moore, JB; Torgerson, D, 2015) |
| "Bone resorption is most sensitive to changes in H+ concentration at a pH of about 7." | 2.42 | Regulation of bone cell function by acid-base balance. ( Arnett, T, 2003) |
| "Interestingly respiratory acidosis, caused by an increase in the partial pressure of carbon dioxide induces far less bone dissolution and resorption and the additional hydrogen ions are not buffered by bone." | 2.41 | Acid-base imbalance and the skeleton. ( Bushinsky, DA, 2001) |
| "Conversely, respiratory acidosis [decreased pH from increased partial pressure of carbon dioxide (Pco(2))] does not appreciably alter Ca homeostasis." | 1.36 | Effect of metabolic and respiratory acidosis on intracellular calcium in osteoblasts. ( Bushinsky, DA; Frick, KK, 2010) |
| "Alkali supplements decrease bone resorption and increase bone mineral density." | 1.35 | The effect of the alkali load of mineral water on bone metabolism: interventional studies. ( Burckhardt, P, 2008) |
| "The potassium bicarbonate was given orally for 18 days in doses (60 to 120 mmol per day) that nearly completely neutralized the endogenous acid." | 1.29 | Improved mineral balance and skeletal metabolism in postmenopausal women treated with potassium bicarbonate. ( Harris, ST; Morris, RC; Ottaway, JH; Sebastian, A; Todd, KM, 1994) |
| "However, the effects on bone resorption of the concentrations of these ions or their transmembrane gradients are unknown." | 1.29 | Acid and base effects on avian osteoclast activity. ( Athanasou, NA; Blair, HC; Carano, A; Schlesinger, PH; Teitelbaum, SL, 1993) |
| "Little or no bone resorption occurred when ambient pH was above about 7." | 1.29 | Modulation of the resorptive activity of rat osteoclasts by small changes in extracellular pH near the physiological range. ( Arnett, TR; Spowage, M, 1996) |
| "DIDS inhibited bone resorption in concentration dependent fashion, without affecting osteoclast viability or survival on bone slices." | 1.28 | Optimal bone resorption by isolated rat osteoclasts requires chloride/bicarbonate exchange. ( Chambers, TJ; Hall, TJ, 1989) |
| "After inhibition of bone resorption with colchicine (1 mg/kg), plasma HCO3 decreased to 16." | 1.26 | The pathophysiology of acid-base changes in chronically phosphate-depleted rats: bone-kidney interactions. ( Agus, ZS; Emmett, M; Goldfarb, S; Narins, RG, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (35.71) | 18.7374 |
| 1990's | 9 (21.43) | 18.2507 |
| 2000's | 8 (19.05) | 29.6817 |
| 2010's | 10 (23.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shea, MK | 1 |
| Dawson-Hughes, B | 2 |
| Müller, WE | 1 |
| Schröder, HC | 1 |
| Schlossmacher, U | 1 |
| Grebenjuk, VA | 1 |
| Ushijima, H | 1 |
| Wang, X | 1 |
| Lambert, H | 1 |
| Frassetto, L | 1 |
| Moore, JB | 1 |
| Torgerson, D | 1 |
| Gannon, R | 1 |
| Burckhardt, P | 4 |
| Lanham-New, S | 1 |
| Tabatabai, LS | 1 |
| Cummings, SR | 1 |
| Tylavsky, FA | 1 |
| Bauer, DC | 1 |
| Cauley, JA | 1 |
| Kritchevsky, SB | 1 |
| Newman, A | 1 |
| Simonsick, EM | 1 |
| Harris, TB | 1 |
| Sebastian, A | 2 |
| Sellmeyer, DE | 1 |
| Wynn, E | 2 |
| Krieg, MA | 2 |
| Aeschlimann, JM | 1 |
| Harris, SS | 1 |
| Palermo, NJ | 1 |
| Castaneda-Sceppa, C | 1 |
| Rasmussen, HM | 1 |
| Dallal, GE | 1 |
| Lanham-New, SA | 1 |
| Pizzorno, J | 1 |
| Frassetto, LA | 1 |
| Katzinger, J | 1 |
| Riihonen, R | 1 |
| Nielsen, S | 1 |
| Väänänen, HK | 1 |
| Laitala-Leinonen, T | 1 |
| Kwon, TH | 1 |
| Frick, KK | 2 |
| Bushinsky, DA | 5 |
| Belavý, DL | 1 |
| Bansmann, PM | 1 |
| Böhme, G | 1 |
| Frings-Meuthen, P | 2 |
| Heer, M | 2 |
| Rittweger, J | 1 |
| Zange, J | 1 |
| Felsenberg, D | 1 |
| Buehlmeier, J | 1 |
| Remer, T | 1 |
| Maser-Gluth, C | 1 |
| Stehle, P | 1 |
| Biolo, G | 1 |
| Krieger, NS | 2 |
| Arnett, T | 1 |
| Ott, SM | 1 |
| LaCroix, AZ | 1 |
| Scholes, D | 1 |
| Ichikawa, LE | 1 |
| Wu, K | 1 |
| Harris, ST | 1 |
| Ottaway, JH | 1 |
| Todd, KM | 1 |
| Morris, RC | 1 |
| Arnett, TR | 2 |
| Boyde, A | 1 |
| Jones, SJ | 1 |
| Taylor, ML | 1 |
| Lemann, J | 2 |
| Pleuss, JA | 1 |
| Gray, RW | 2 |
| Blair, HC | 2 |
| Schlesinger, PH | 2 |
| Ross, FP | 1 |
| Teitelbaum, SL | 2 |
| Carano, A | 1 |
| Athanasou, NA | 1 |
| Spowage, M | 1 |
| Parker, WR | 1 |
| Alexander, KM | 1 |
| Beck, N | 1 |
| Webster, SK | 1 |
| Dominguez, JH | 1 |
| Raisz, LG | 1 |
| Emmett, M | 1 |
| Goldfarb, S | 1 |
| Agus, ZS | 1 |
| Narins, RG | 1 |
| Orsatti, MB | 1 |
| Fucci, LL | 1 |
| Valenti, JL | 1 |
| Puche, RC | 1 |
| Dedrick, DK | 1 |
| Mase, C | 1 |
| Ranger, W | 1 |
| Burney, RE | 1 |
| Abu Damir, H | 1 |
| Scott, D | 1 |
| Loveridge, N | 1 |
| Buchan, W | 1 |
| Milne, J | 1 |
| Hall, TJ | 1 |
| Chambers, TJ | 1 |
| Maierhofer, WJ | 1 |
| Cheung, HS | 1 |
| Ikeda, K | 1 |
| Matsumoto, T | 1 |
| Ogata, E | 1 |
| Kleeman, CR | 1 |
| Better, OS | 1 |
| Cordy, PE | 1 |
| Gagnon, R | 1 |
| Taves, DR | 1 |
| Kaye, M | 1 |
| Cochran, M | 1 |
| Bulusu, L | 1 |
| Horsman, A | 1 |
| Stasiak, L | 1 |
| Nordin, BE | 1 |
| Mueller, WJ | 1 |
| Brubaker, RL | 1 |
| Gay, CV | 1 |
| Boelkins, JN | 1 |
| Mahgoub, A | 1 |
| Stern, PH | 1 |
| Binswanger, U | 1 |
| Sherrard, D | 1 |
| Rich, C | 1 |
| Curtis, FK | 1 |
| Rubini, ME | 1 |
| Cobun, JW | 1 |
| Massry, SG | 1 |
| Shinaberger, JH | 1 |
| Barzel, US | 1 |
| Jowsey, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Musculoskeletal Benefits of Bicarbonate in Older Adults - A Dose-Finding Trial[NCT01475214] | Phase 2 | 244 participants (Actual) | Interventional | 2012-01-31 | Completed | ||
| Efficacy of Potassium Citrate in the Treatment of Postmenopausal Osteopenia. A Randomized, Placebo-controlled, Double Blind Investigation.[NCT02731820] | 40 participants (Actual) | Interventional | 2015-09-01 | Completed | |||
| Evaluation of the Effects of Bicarbonate-calcium Water in Premenopausal and Postmenopausal Women as a Prevention of Osteoporosis[NCT05854342] | 120 participants (Actual) | Interventional | 2021-06-01 | Completed | |||
| Effect of Potassium Bicarbonate on Bone and Muscle[NCT00357214] | 171 participants (Actual) | Interventional | 2006-09-30 | Completed | |||
| A Pilot Study to Assess the Effects of Regulating Urine pH Levels for Alleviating Chronic Joint Pain[NCT01421160] | Phase 1 | 0 participants (Actual) | Interventional | 2011-07-31 | Withdrawn (stopped due to PI left the institution prior to any data being collected) | ||
| Effects of a Cocktail XXS-2A/Omega-3 on Insulin Sensitivity and Oxidative Stress During a 20-day Period of Physical Inactivity: a Controlled, Randomized Pilot Study on 20 Healthy Men[NCT03313869] | 20 participants (Actual) | Interventional | 2015-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Describe and compare changes in 24-hour urinary nitrogen in the low and high dose and KHCO3 group and in placebo. (NCT01475214)
Timeframe: 84 days
| Intervention | mmol/day (Mean) | |
|---|---|---|
| baseline 24-hr urine nitrogen | change in 24-hr urine nitrogen | |
| Inactive Capsule | 864 | -21.0 |
| Potassium Bicarbonate Higher Dose | 834 | -16.4 |
| Potassium Bicarbonate Low Dose | 769 | -29.4 |
Describe and compare changes in urinary N-telopeptide (NTX) across the placebo and Potassium Bicarbonate (KHCO3) doses. (NCT01475214)
Timeframe: 84 days
| Intervention | nmol/day (Mean) | |
|---|---|---|
| baseline 24-hr urinary NTX | change in NTX | |
| Inactive Placebo Capsule | 241 | -14 |
| Potassium Bicarbonate Higher Dose | 230 | -43 |
| Potassium Bicarbonate Low Dose | 240 | -53 |
"Bone-specific alkaline phosphatase (BAP) is a specific product of osteoblasts; it is considered as a marker of bone formation. The concentration of BAP (µg/L) will be measured at T0, T3, and T6 on serum samples (fasting morning samples) using commercially available reagents and following the manufacturer's protocol. At the end of the study, the results will be aggregated as mean ± standard of the mean, median and min-max range. Data will be statistically analyzed in order to compare the activity of Potassium citrate versus Placebo (unpaired analysis) and to evaluate the effect of Potassium Citrate and Placebo over time (paired analysis).~Differences will be considered to be statistically significant for p-value <0.05." (NCT02731820)
Timeframe: Baseline (T0), 3 months (T3) 6 months (T6)
| Intervention | µg/L (Mean) | ||
|---|---|---|---|
| Baseline (T0) | 3 months (T3) | 6 months (T6) | |
| Control Group, Placebo | 20.36 | 18.27 | 15.79 |
| Treatment Group, Potassium Citrate | 21.89 | 19.81 | 16.83 |
"N-terminal propeptide of type I procollagen (P1NP) is a product of the conversion of procollagen to collagen; it is considered as a marker of bone formation. The concentration of P1NP (pg/L) will be measured at T0, T3, and T6 on serum samples (fasting morning samples) using commercially available reagents and following the manufacturer's protocol. At the end of the study, the results will be aggregated as mean ± standard of the mean, median and min-max range. Data will be statistically analyzed in order to compare the activity of Potassium citrate versus Placebo (unpaired analysis) and to evaluate the effect of Potassium Citrate and Placebo over time (paired analysis).~Differences will be considered to be statistically significant for p-value <0.05." (NCT02731820)
Timeframe: Baseline (T0), 3 months (T3) 6 months (T6)
| Intervention | pg/L (Mean) | ||
|---|---|---|---|
| Baseline (T0) | 3 months (T3) | 6 months (T6) | |
| Control Group, Placebo | 18.82 | 18.39 | 16.77 |
| Treatment Group, Potassium Citrate | 17.45 | 16.24 | 14.97 |
"Tartrate-resistant acid phosphatase 5b isoenzyme (TRAcP5b) is a specific product of osteoclasts; it is considered as a marker of bone resorption. The concentration of TRAcP5B (U/L) will be measured at T0, T3, and T6 on serum samples (fasting morning samples) using commercially available reagents and following the manufacturer's protocol. At the end of the study, the results will be aggregated as mean ± standard of the mean, median and min-max range. Data will be statistically analyzed in order to compare the activity of Potassium Citrate versus Placebo (unpaired analysis) and to evaluate the effect of Potassium Citrate and Placebo over time (paired analysis).~Differences will be considered to be statistically significant for p-value <0.05." (NCT02731820)
Timeframe: Baseline (T0), 3 months (T3) 6 months (T6)
| Intervention | U/L (Mean) | ||
|---|---|---|---|
| Baseline (T0) | 3 months (T3) | 6 months (T6) | |
| Control Group, Placebo | 2.64 | 2.85 | 2.25 |
| Treatment Group, Potassium Citrate | 2.35 | 2.79 | 2.69 |
"Carboxyterminal cross-linked telopeptide of type I collagen (CTX) is a degradation product of the type I collagen; it is considered as a marker of bone resorption. The concentration of CTX (µg/L) will be measured at T0, T3, and T6 on serum samples (fasting morning samples) using commercially available reagents and following the manufacturer's protocol.~At the end of the study, the results will be aggregated as mean ± standard of the mean, median and min-max range. Data will be statistically analyzed in order to compare the activity of Potassium citrate versus Placebo (unpaired analysis) and to evaluate the effect of Potassium Citrate and Placebo over time (paired analysis).~Differences will be considered to be statistically significant for p-value <0.05." (NCT02731820)
Timeframe: Baseline (T0), 3 months (T3) 6 months (T6)
| Intervention | µg/L (Mean) | ||
|---|---|---|---|
| Baseline (T0) | 3 months (T3) | 6 months (T6) | |
| Control Group, Placebo | 0.64 | 0.56 | 0.54 |
| Treatment Group, Potassium Citrate | 0.64 | 0.63 | 0.53 |
Change in 24-hr urinary N-telopeptide/creatinine measured at baseline and 3 months (NCT00357214)
Timeframe: 3 month change in 24-hr urine values
| Intervention | nmol/mmol (Mean) |
|---|---|
| Potassium Bicarbonate | -6.25 |
| Sodium Bicarbonate | -3.36 |
| Potassium Chloride | -0.14 |
| Microcrystalline Cellulose | 0.5 |
7 reviews available for hydrogen carbonate and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
The effect of supplementation with alkaline potassium salts on bone metabolism: a meta-analysis.
Topics: Bicarbonates; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Bone Resorption; Calc | 2015 |
Regulation of bone cell function by acid-base balance.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Aging; Bicarbonates; Bone and Bones; Bone Reso | 2003 |
Potassium causes calcium retention in healthy adults.
Topics: Animals; Bicarbonates; Bone Resorption; Calcitriol; Calcium; Humans; Male; Potassium; Potassium Comp | 1993 |
Recent advances toward understanding osteoclast physiology.
Topics: Bicarbonates; Biological Transport, Active; Bone Resorption; Calcium; Carbonic Acid; Cell Nucleus; C | 1993 |
Acid-base imbalance and the skeleton.
Topics: Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Aging; Bicarbonates; Bone and Bones; Bone Remo | 2001 |
[Thyroid and parathyroid diseases associated with renal tubular acidosis].
Topics: Absorption; Acid-Base Equilibrium; Acidosis, Renal Tubular; Animals; Bicarbonates; Bone Resorption; | 1985 |
Disordered divalent ion metabolism in kidney disease: comments on pathogenesis and treatment.
Topics: Bicarbonates; Bone Resorption; Calcium; Cholecalciferol; Chronic Kidney Disease-Mineral and Bone Dis | 1973 |
6 trials available for hydrogen carbonate and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Association of Urinary Citrate With Acid-Base Status, Bone Resorption, and Calcium Excretion in Older Men and Women.
Topics: Acid-Base Equilibrium; Aged; Aged, 80 and over; Aging; Bicarbonates; Bone Remodeling; Bone Resorptio | 2018 |
Alkaline mineral water lowers bone resorption even in calcium sufficiency: alkaline mineral water and bone metabolism.
Topics: Adolescent; Adult; Alkalies; Bicarbonates; Bone and Bones; Bone Resorption; Calcium, Dietary; Collag | 2009 |
Treatment with potassium bicarbonate lowers calcium excretion and bone resorption in older men and women.
Topics: Aged; Bicarbonates; Bone Resorption; Calcium; Collagen Type I; Creatinine; Double-Blind Method; Fema | 2009 |
Alkaline salts to counteract bone resorption and protein wasting induced by high salt intake: results of a randomized controlled trial.
Topics: Adult; Alkalies; Bicarbonates; Bone and Bones; Bone Resorption; Cross-Over Studies; Dietary Suppleme | 2012 |
Effects of three years of low-dose thiazides on mineral metabolism in healthy elderly persons.
Topics: Aged; Bicarbonates; Bone and Bones; Bone Density; Bone Resorption; Calcium; Calcium, Dietary; Dose-R | 2008 |
Hydrochlorothiazide inhibits bone resorption in men despite experimentally elevated serum 1,25-dihydroxyvitamin D concentrations.
Topics: Acid-Base Equilibrium; Adult; Bicarbonates; Body Weight; Bone Resorption; Calcitriol; Calcium; Creat | 1985 |
29 other studies available for hydrogen carbonate and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Induction of carbonic anhydrase in SaOS-2 cells, exposed to bicarbonate and consequences for calcium phosphate crystal formation.
Topics: Acetazolamide; Ascorbic Acid; Bicarbonates; Bone Resorption; Calcium Phosphates; Carbonic Anhydrase | 2013 |
Arterialized venous bicarbonate is associated with lower bone mineral density and an increased rate of bone loss in older men and women.
Topics: Aged; Aging; Bicarbonates; Blood Gas Analysis; Body Composition; Bone Density; Bone Resorption; Coho | 2015 |
Postgraduate Symposium: Positive influence of nutritional alkalinity on bone health.
Topics: Acid-Base Equilibrium; Acidosis; Adult; Aged; Bicarbonates; Bone and Bones; Bone Density; Bone Resor | 2010 |
Diet-induced acidosis: is it real and clinically relevant?
Topics: Acidosis; Algorithms; Bicarbonates; Bone Density; Bone Resorption; Carbon Dioxide; Diet; Female; Hom | 2010 |
Degradation of hydroxyapatite in vivo and in vitro requires osteoclastic sodium-bicarbonate co-transporter NBCn1.
Topics: Animals; Bicarbonates; Bone and Bones; Bone Resorption; Calcium; Calcium Metabolism Disorders; Cell | 2010 |
Effect of metabolic and respiratory acidosis on intracellular calcium in osteoblasts.
Topics: Acidosis; Acidosis, Respiratory; Animals; Animals, Newborn; Bicarbonates; Bone Resorption; Calcium; | 2010 |
Changes in intervertebral disc morphology persist 5 mo after 21-day bed rest.
Topics: Adult; Bed Rest; Bicarbonates; Bone Resorption; Cross-Sectional Studies; Germany; Head-Down Tilt; Hu | 2011 |
Cortisol inhibits acid-induced bone resorption in vitro.
Topics: Acids; Animals; Bicarbonates; Bone Resorption; Calcium; Carbon Dioxide; Culture Media; Dinoprostone; | 2002 |
The effect of the alkali load of mineral water on bone metabolism: interventional studies.
Topics: Acid-Base Equilibrium; Bicarbonates; Bone Resorption; Calcium; Humans; Hydrogen-Ion Concentration; K | 2008 |
Effects of medium acidification by alteration of carbon dioxide or bicarbonate concentrations on the resorptive activity of rat osteoclasts.
Topics: Acidosis; Animals; Bicarbonates; Bone Resorption; Carbon Dioxide; Cell Movement; Cells, Cultured; Hy | 1994 |
Improved mineral balance and skeletal metabolism in postmenopausal women treated with potassium bicarbonate.
Topics: Aged; Bicarbonates; Bone and Bones; Bone Density; Bone Resorption; Calcium; Female; Humans; Middle A | 1994 |
Effects of medium acidification by alteration of carbon dioxide or bicarbonate concentrations on the resorptive activity of rat osteoclasts.
Topics: Acid Phosphatase; Animals; Bicarbonates; Bone Resorption; Carbon Dioxide; Cells, Cultured; Culture M | 1994 |
Acid and base effects on avian osteoclast activity.
Topics: Acid-Base Equilibrium; Animals; Bicarbonates; Bone Resorption; Carbon Dioxide; Cells, Cultured; Dose | 1993 |
Modulation of the resorptive activity of rat osteoclasts by small changes in extracellular pH near the physiological range.
Topics: Analysis of Variance; Animals; Bicarbonates; Bone Resorption; Buffers; Carbonates; Cells, Cultured; | 1996 |
Prostaglandins regulate acid-induced cell-mediated bone resorption.
Topics: Acidosis; Animals; Animals, Newborn; Bicarbonates; Bone and Bones; Bone Resorption; Calcium; Carbon | 2000 |
Effects of acute metabolic acidosis on parathyroid hormone action and calcium mobilization.
Topics: Acidosis; Animals; Bicarbonates; Bone Resorption; Calcitonin; Calcium; Glomerular Filtration Rate; H | 1976 |
Effects of changing hydrogen ion, carbonic acid, and bicarbonate concentrations on bone resorption in vitro.
Topics: Acidosis; Alkalosis; Animals; Bicarbonates; Bone Resorption; Calcium; Carbonates; Carbonic Acid; Cul | 1979 |
The pathophysiology of acid-base changes in chronically phosphate-depleted rats: bone-kidney interactions.
Topics: Acid-Base Imbalance; Animals; Bicarbonates; Bone and Bones; Bone Resorption; Calcium; Colchicine; Ki | 1977 |
Effect of bicarbonate feeding on immobilization osteoporosis in the rat.
Topics: Animals; Bicarbonates; Bone and Bones; Bone Resorption; Calcium; Immobilization; Osteoporosis; Rats | 1976 |
The effects of intraosseous infusion on the growth plate in a nestling rabbit model.
Topics: Animals; Animals, Newborn; Bicarbonates; Bone Resorption; Growth Plate; Infusions, Parenteral; Micro | 1992 |
The effects of feeding diets containing either NaHCO3 or NH4Cl on indices of bone formation and resorption and on mineral balance in the lamb.
Topics: Ammonium Chloride; Animals; Bicarbonates; Bone Development; Bone Resorption; Calcium; Diet; Minerals | 1991 |
Optimal bone resorption by isolated rat osteoclasts requires chloride/bicarbonate exchange.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo | 1989 |
Bone disease in hemodialysis patients with particular reference to the effect of fluoride.
Topics: Adult; Alkaline Phosphatase; Bicarbonates; Blood Urea Nitrogen; Bone Resorption; Calcium; Chronic Ki | 1974 |
Hypocalcaemia and bone disease in renal failure.
Topics: Absorptiometry, Photon; Acidosis; Adolescent; Adult; Aged; Alkaline Phosphatase; Bicarbonates; Biops | 1973 |
Mechanisms of bone resorption in laying hens.
Topics: Animals; Bicarbonates; Bone and Bones; Bone Resorption; Calcium; Calcium Isotopes; Chickens; Citrate | 1973 |
Carbon dioxide and the effect of parathyroid hormone on bone in vitro.
Topics: Acetazolamide; Animals; Bicarbonates; Bone and Bones; Bone Resorption; Buffers; Calcium Radioisotope | 1974 |
Dialysis bone disease. A quantitative histologic study.
Topics: Adult; Alkaline Phosphatase; Bicarbonates; Biopsy; Blood Urea Nitrogen; Bone Diseases; Bone Resorpti | 1974 |
Renal osteodystrophy; some therapeutic consideration relative to long-term dialysis and transplantation.
Topics: Acidosis; Bicarbonates; Bone Diseases; Bone Resorption; Calcium; Humans; Hypercalcemia; Kidney Failu | 1969 |
The effects of chronic acid and alkali administration on bone turnover in adult rats.
Topics: Ammonium Chloride; Animals; Bicarbonates; Body Weight; Bone and Bones; Bone Resorption; Calcium; Cal | 1969 |