hydrogen carbonate has been researched along with Blood Pressure, High in 148 studies
Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.
Excerpt | Relevance | Reference |
---|---|---|
"The effects of amiloride hydrochloride on thiazide-induced hypokalemia were evaluated." | 9.05 | Response of thiazide-induced hypokalemia to amiloride. ( Chan, L; Maronde, RF; Milgrom, M; Vlachakis, ND, 1983) |
"The effect of a six-week course of spironolactone 300 mg/day was examined in 25 unselected patients with essential hypertension." | 9.04 | Spironolactone in essential hypertension: evidence against its effect through mineralocorticoid antagonism. ( Edmonds, CJ; Hoffbrand, BI; Smith, T, 1976) |
"In uninephrectomized rats given desoxycorticosterone (DOC) and a fixed amount of dietary sodium, we sought to determine if the anionic component of the sodium salt consumed could be a pathogenetic determinant of the occurrence and maintenance of hypertension." | 7.67 | Dietary chloride and bicarbonate as determinants of desoxycorticosterone hypertension. ( Kurtz, TW; Morris, RC, 1984) |
"We report two diabetic patients who developed lactic acidosis following the use of Buformin." | 7.67 | [Lactic acidosis in diabetic patients associated with buformin]. ( Díaz, RA; Hernández, G; Huidobro, F; Jimenez, R; Pérez, H; Torres, H; Videla, C, 1989) |
"Treatment with procainamide not only inhibited the overexpression of DNMT1 but also diminished the overproduction of IL-6 in rhabdomyolysis rats." | 5.43 | Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats. ( Chen, SJ; Hii, HP; Ka, SM; Liao, MH; Shih, CC; Tsao, CM; Wu, CC, 2016) |
"Chlorthalidone (50 mg daily) was given for 14 days." | 5.26 | Initial potassium loss and hypokalaemia during chlorthalidone administration in patients with essential hypertension: the influence of dietary sodium restriction. ( Landmann-Suter, R; Struyvenberg, A, 1978) |
" We conducted a double-blind, placebo-controlled trial in 81 patients with diabetes, hypertension, and albuminuria (urine albumin-to-creatinine ratio > or =300 mg/g) who all received lisinopril (80 mg once daily)." | 5.14 | Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy. ( Adams-Huet, B; Mehdi, UF; Raskin, P; Toto, RD; Vega, GL, 2009) |
"The effects of amiloride hydrochloride on thiazide-induced hypokalemia were evaluated." | 5.05 | Response of thiazide-induced hypokalemia to amiloride. ( Chan, L; Maronde, RF; Milgrom, M; Vlachakis, ND, 1983) |
"The effect of a six-week course of spironolactone 300 mg/day was examined in 25 unselected patients with essential hypertension." | 5.04 | Spironolactone in essential hypertension: evidence against its effect through mineralocorticoid antagonism. ( Edmonds, CJ; Hoffbrand, BI; Smith, T, 1976) |
"We used myocytes from Wistar, SHR, losartan-treated SHR (Los-SHR), and Angiotensin II (Ang II)-induced cardiac hypertrophy." | 3.80 | Reduced sarcolemmal expression and function of the NBCe1 isoform of the Na⁺-HCO₃⁻ cotransporter in hypertrophied cardiomyocytes of spontaneously hypertensive rats: role of the renin-angiotensin system. ( Aiello, EA; Caldiz, CI; Ciancio, MC; De Giusti, VC; Orlowski, A, 2014) |
"In uninephrectomized rats given desoxycorticosterone (DOC) and a fixed amount of dietary sodium, we sought to determine if the anionic component of the sodium salt consumed could be a pathogenetic determinant of the occurrence and maintenance of hypertension." | 3.67 | Dietary chloride and bicarbonate as determinants of desoxycorticosterone hypertension. ( Kurtz, TW; Morris, RC, 1984) |
"In 116 patients with coronary heart disease, essential hypertension, acute and chronic glomerulonephritis and pyelonephritis, the authors observed differences in the excretion of the ions of 42K, stable potassium, 24Na, stable sodium, chlorine as well as in the value of diuresis during the administration of equimolar solutions of potassium hydrocarbonate and potassium chloride, sodium hydrocarbonate and sodium chloride labeled with 42K and 24Na respectively." | 3.67 | [Metabolism of potassium and sodium when administered with different anions to patients with ischemic heart disease and arterial hypertension]. ( Barnatskiĭ, VN; Korsunskiĭ, VN; Moiseev, AA; Stoliarov, VP; Vikhrov, NI, 1984) |
"We report two diabetic patients who developed lactic acidosis following the use of Buformin." | 3.67 | [Lactic acidosis in diabetic patients associated with buformin]. ( Díaz, RA; Hernández, G; Huidobro, F; Jimenez, R; Pérez, H; Torres, H; Videla, C, 1989) |
"In rats given desoxycorticosterone (DOC), the recently reported finding that a normal amount of dietary sodium chloride (NaCl) induces hypertension but an equimolar amount of sodium bicarbonate (NaHCO3) does not, might be a consequence of the differing effects of the two sodium salts on the metabolism of calcium." | 3.67 | Dietary chloride as a determinant of disordered calcium metabolism in salt-dependent hypertension. ( Kurtz, TW; Morris, RC, 1985) |
"The role of sodium and its accompanying anion for the development of DOCA-salt hypertension was studied in uninephrectomized DOCA-treated weanling Wistar rats which were fed a diet containing either sodium chloride or sodium bicarbonate (170 mmol/kg)." | 3.67 | The importance of sodium and chloride ions for the development of DOCA-NaCl hypertension: a haemodynamic study. ( Govyrin, VA; Jelínek, J; Kunes, J; Leont'eva, GR; Zicha, J, 1986) |
" Prevention of the development of hypertension in SHR by hydralazine treatment from weaning did not increase pH or bicarbonate compared with untreated SHR, indicating that the metabolic acidosis in the SHR was not a consequence of raised blood pressure." | 3.67 | Disturbance of acid-base balance in the young spontaneously hypertensive rat. ( Drüeke, T; Lacour, B; Lucas, PA; McCarron, DA, 1987) |
"In a study of 50 patients with uncomplicated arterial hypertension the administration of hydrochlorothiazide, 50 to 100 mg daily or every other day, with or without reserpine, 0." | 3.66 | Hypokalemia during the treatment of arterial hypertension with diuretics. ( Beauchemin, M; Gougoux, A; Lemieux, G; Vinay, P, 1980) |
"Studies were carried out in 69 patients with essential hypertension to examine the relationship between changes in plasma renin activity (PRA) and arterial pressure (BP) in response to a beta-adrenergic blocking agent, propranolol." | 3.65 | Dissociation between renin and arterial pressure responses to beta-adrenergic blockade in human essential hypertension. ( Bravo, EL; Dustan, HP; Lewis, JW; Tarazi, RC, 1975) |
"Hypocitraturia and hypercalciuria are risk factors for calcium stone disease." | 2.47 | Diet-induced metabolic acidosis. ( Adeva, MM; Souto, G, 2011) |
"Metabolic alkalosis is a primary pathophysiologic event characterized by the gain of bicarbonate or the loss of nonvolatile acid from extracellular fluid." | 2.41 | Metabolic alkalosis. ( Khanna, A; Kurtzman, NA, 2001) |
"Obstructive sleep apnea is characterized by intermittent hypoxia and hypercapnia." | 1.46 | Independent associations between arterial bicarbonate, apnea severity and hypertension in obstructive sleep apnea. ( Eskandari, D; Grote, L; Hedner, J; Penzel, T; Schneider, H; Zou, D, 2017) |
"Treatment with procainamide not only inhibited the overexpression of DNMT1 but also diminished the overproduction of IL-6 in rhabdomyolysis rats." | 1.43 | Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats. ( Chen, SJ; Hii, HP; Ka, SM; Liao, MH; Shih, CC; Tsao, CM; Wu, CC, 2016) |
"Many end stage renal disease (ESRD) patients get their first nephrologic care under critical clinical conditions and without previous diagnosis of chronic renal failure (CRF), a situation even worse than the late referral of CRF patients for nephrologic treatment." | 1.32 | Risk factors for hospital death of patients with end-stage renal disease without previous diagnosis of severe chronic renal failure arriving in an emergency situation at the hospital. ( Abdulkader, RC; Burdmann, EA; Oliveira, GM; Zanetta, DM, 2003) |
"Metabolic acidosis has recently been observed in rat models of salt-sensitive genetic hypertension." | 1.28 | Abnormal acid-base regulation in salt-sensitive normotensive man. ( Distler, A; Sharma, AM, 1991) |
" In the Sprague-Dawley rat, acute and chronic administration of sodium salts other than sodium chloride failed to suppress plasma renin activity, whereas renin was inhibited by both sodium chloride and by selective chloride (without sodium) loading." | 1.27 | Effect of chloride on renin and blood pressure responses to sodium chloride. ( Galla, JH; Kotchen, TA; Luke, RG; Ott, CE; Whitescarver, S, 1983) |
"Amiloride was disproportionately potent in lowering serum bicarbonate, and the data do not suggest that these drugs elevate plasma potassium simply by correcting metabolic alkalosis." | 1.26 | Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients. ( Fraser, R; Hettiarachchi, J; Morton, JJ; Ramsay, LE, 1980) |
"Chlorthalidone (50 mg daily) was given for 14 days." | 1.26 | Initial potassium loss and hypokalaemia during chlorthalidone administration in patients with essential hypertension: the influence of dietary sodium restriction. ( Landmann-Suter, R; Struyvenberg, A, 1978) |
"If hypokalemia is present in patients receiving thiazides who have had an acute myocardial infarction, it should be corrected so as to remove this predisposing cause of ventricular fibrillation." | 1.26 | Thiazide-induced hypokalemia. Association with acute myocardial infarction and ventricular fibrillation. ( Duke, M, 1978) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 88 (59.46) | 18.7374 |
1990's | 25 (16.89) | 18.2507 |
2000's | 15 (10.14) | 29.6817 |
2010's | 16 (10.81) | 24.3611 |
2020's | 4 (2.70) | 2.80 |
Authors | Studies |
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Lombari, P | 1 |
Mallardo, M | 1 |
Petrazzuolo, O | 1 |
Amruthraj Nagoth, J | 1 |
Fiume, G | 1 |
Scanni, R | 1 |
Iervolino, A | 1 |
Damiano, S | 1 |
Coppola, A | 1 |
Borriello, M | 1 |
Ingrosso, D | 1 |
Perna, AF | 1 |
Zacchia, M | 1 |
Trepiccione, F | 1 |
Capasso, G | 1 |
Meremo, A | 1 |
Paget, G | 1 |
Duarte, R | 1 |
Dickens, C | 1 |
Dix-Peek, T | 1 |
Bintabara, D | 1 |
Naicker, S | 1 |
Wesson, DE | 1 |
Dobre, M | 1 |
Pajewski, NM | 1 |
Beddhu, S | 3 |
Chonchol, M | 1 |
Hostetter, TH | 1 |
Li, P | 1 |
Rahman, M | 1 |
Servilla, K | 1 |
Weiner, DE | 1 |
Wright, JT | 1 |
Raphael, KL | 2 |
Eskandari, D | 1 |
Zou, D | 1 |
Grote, L | 1 |
Schneider, H | 1 |
Penzel, T | 1 |
Hedner, J | 1 |
Simão, S | 1 |
Gomes, P | 1 |
Pinho, MJ | 1 |
Soares-da-Silva, P | 1 |
Mandel, EI | 1 |
Forman, JP | 1 |
Curhan, GC | 1 |
Taylor, EN | 1 |
Orlowski, A | 1 |
Ciancio, MC | 1 |
Caldiz, CI | 1 |
De Giusti, VC | 1 |
Aiello, EA | 1 |
Hung, AM | 1 |
Hakim, RM | 1 |
Chung, F | 1 |
Abdullah, HR | 1 |
Liao, P | 1 |
Shih, CC | 1 |
Hii, HP | 1 |
Tsao, CM | 1 |
Chen, SJ | 1 |
Ka, SM | 1 |
Liao, MH | 1 |
Wu, CC | 1 |
Pena-Polanco, JE | 1 |
Fried, LF | 1 |
Kendrick, JB | 1 |
Zelnick, L | 1 |
Chonchol, MB | 1 |
Siscovick, D | 1 |
Hoofnagle, AN | 1 |
Ix, JH | 1 |
Sarnak, M | 1 |
Shlipak, MG | 1 |
Kestenbaum, B | 1 |
de Boer, IH | 1 |
Seidler, U | 1 |
Singh, A | 1 |
Chen, M | 1 |
Cinar, A | 1 |
Bachmann, O | 1 |
Zheng, W | 1 |
Wang, J | 1 |
Yeruva, S | 1 |
Riederer, B | 1 |
Mehdi, UF | 1 |
Adams-Huet, B | 1 |
Raskin, P | 1 |
Vega, GL | 1 |
Toto, RD | 1 |
He, FJ | 1 |
Marciniak, M | 1 |
Carney, C | 1 |
Markandu, ND | 1 |
Anand, V | 1 |
Fraser, WD | 1 |
Dalton, RN | 1 |
Kaski, JC | 1 |
MacGregor, GA | 1 |
Crajoinas, RO | 1 |
Lessa, LM | 1 |
Carraro-Lacroix, LR | 1 |
Davel, AP | 1 |
Pacheco, BP | 1 |
Rossoni, LV | 1 |
Malnic, G | 1 |
Girardi, AC | 1 |
Wei, G | 1 |
Baird, BC | 1 |
Greene, T | 1 |
Tapolyai, M | 1 |
Uysal, A | 1 |
Dossabhoy, NR | 1 |
Zsom, L | 1 |
Szarvas, T | 1 |
Lengvárszky, Z | 1 |
Fülöp, T | 1 |
Adeva, MM | 1 |
Souto, G | 1 |
Scialla, JJ | 1 |
Appel, LJ | 1 |
Astor, BC | 1 |
Miller, ER | 1 |
Woodward, M | 1 |
Parekh, RS | 1 |
Anderson, CA | 1 |
Dodd, MS | 1 |
Ball, DR | 1 |
Schroeder, MA | 1 |
Le Page, LM | 1 |
Atherton, HJ | 1 |
Heather, LC | 1 |
Seymour, AM | 1 |
Ashrafian, H | 1 |
Watkins, H | 1 |
Clarke, K | 1 |
Tyler, DJ | 1 |
Abdulkader, RC | 1 |
Zanetta, DM | 1 |
Oliveira, GM | 1 |
Burdmann, EA | 1 |
THOMAS, J | 1 |
THOMAS, E | 1 |
BRIGGS, AP | 1 |
FINDLEY, T | 1 |
HARMS, WS | 1 |
TALSO, PJ | 1 |
YOUNG, L | 1 |
TANSEY, WJ | 1 |
WILLUMSEN, J | 2 |
CLAUSEN, E | 1 |
GALSKOV, A | 1 |
SCHREINER, GE | 1 |
MEES, EJ | 1 |
GEYSKES, GG | 1 |
ENSON, Y | 1 |
BERHNARD, WF | 1 |
DANIS, R | 1 |
GROSS, RE | 1 |
Lameire, N | 1 |
TOSTESON, DC | 1 |
DEFRIEZ, AI | 1 |
ABRAMS, M | 1 |
GOTTSCHALK, CW | 1 |
LANDIS, EM | 1 |
REISZ, O | 1 |
Bocchi, B | 1 |
Kenouch, S | 1 |
Lamarre-Cliche, M | 1 |
Muffat-Joly, M | 1 |
Capron, MH | 1 |
Fiet, J | 1 |
Morineau, G | 1 |
Azizi, M | 1 |
Bonvalet, JP | 1 |
Farman, N | 1 |
Schmidlin, O | 4 |
Tanaka, M | 4 |
Bollen, AW | 1 |
Yi, SL | 2 |
Morris, RC | 7 |
Cuende, N | 1 |
Miranda, B | 1 |
Cañón, JF | 1 |
Garrido, G | 1 |
Matesanz, R | 1 |
Wall, SM | 1 |
Kurtz, TW | 3 |
Dubois, D | 1 |
Petitcolas, J | 1 |
Temperville, B | 1 |
Klepper, A | 1 |
Catherine, P | 1 |
Kotchen, TA | 2 |
Luke, RG | 1 |
Ott, CE | 2 |
Galla, JH | 1 |
Whitescarver, S | 1 |
Korsunskiĭ, VN | 1 |
Moiseev, AA | 1 |
Barnatskiĭ, VN | 3 |
Stoliarov, VP | 1 |
Vikhrov, NI | 2 |
Whitescarver, SA | 1 |
Jackson, BA | 1 |
Guthrie, GP | 1 |
Maronde, RF | 1 |
Milgrom, M | 1 |
Vlachakis, ND | 1 |
Chan, L | 1 |
Phelps, KR | 1 |
Lieberman, RL | 1 |
Oh, MS | 1 |
Carroll, HJ | 1 |
Kotenko, VA | 1 |
Goroiaev, BI | 1 |
Ramsay, LE | 1 |
Hettiarachchi, J | 1 |
Fraser, R | 3 |
Morton, JJ | 1 |
Lemieux, G | 1 |
Beauchemin, M | 1 |
Vinay, P | 1 |
Gougoux, A | 1 |
Scuteri, A | 1 |
Jensen, PE | 1 |
Aalkjaer, C | 2 |
Pérez, NG | 2 |
Alvarez, BV | 1 |
Camilión de Hurtado, MC | 2 |
Cingolani, HE | 2 |
Good, DW | 1 |
Caflisch, CR | 1 |
George, T | 1 |
Batlle, D | 2 |
Redon, J | 2 |
Gutterman, C | 1 |
LaPointe, M | 1 |
Saleh, A | 1 |
Sharma, A | 1 |
Rombola, G | 1 |
Ye, M | 1 |
Alsheikha, W | 1 |
Gomez, L | 1 |
Sharma, AM | 2 |
Cetto, C | 1 |
Schorr, U | 1 |
Spies, KP | 1 |
Distler, A | 2 |
Sudhir, K | 1 |
Yock, PG | 1 |
Connolly, AJ | 1 |
Raja, RM | 1 |
Lerner, L | 1 |
Morris, M | 1 |
Lijnen, P | 1 |
Orosz, DE | 1 |
Hopfer, U | 1 |
Górriz, JL | 1 |
Sancho, A | 1 |
Lopez-Martin, JM | 1 |
Alcoy, E | 1 |
Catalán, C | 1 |
Pallardó, LM | 1 |
Smolarczyk, R | 1 |
Wójcicka-Jagodzińska, J | 1 |
Romejko, E | 1 |
Czajkowski, K | 1 |
Piekarski, P | 1 |
Teliga-Czajkowska, J | 1 |
Kuczyńska-Sicińska, J | 1 |
Cicco, G | 1 |
van der Kleij, AJ | 1 |
Passavanti, G | 1 |
Baldassare, G | 1 |
Manicone, A | 1 |
Vicenti, P | 1 |
Marra, M | 1 |
Izzo, P | 1 |
Coratelli, P | 1 |
Pirelli, A | 1 |
Sebastian, A | 2 |
Forman, A | 2 |
Mazouz, H | 1 |
Kacso, I | 1 |
Ghazali, A | 1 |
El Esper, N | 1 |
Moriniere, P | 1 |
Makdassi, R | 1 |
Hardy, P | 1 |
Westeel, PF | 1 |
Achard, JM | 1 |
Pruna, A | 1 |
Fournier, A | 1 |
Frassetto, L | 1 |
Halperin, ML | 1 |
Kamel, KS | 1 |
Ushikubi, F | 1 |
Sugimoto, Y | 1 |
Ichikawa, A | 1 |
Narumiya, S | 1 |
Chipperfield, AR | 1 |
Harper, AA | 1 |
Olson, JL | 1 |
Khanna, A | 1 |
Kurtzman, NA | 1 |
Cruz, DN | 1 |
Simon, DB | 1 |
Nelson-Williams, C | 1 |
Farhi, A | 1 |
Finberg, K | 1 |
Burleson, L | 1 |
Gill, JR | 1 |
Lifton, RP | 1 |
Landmann-Suter, R | 1 |
Struyvenberg, A | 1 |
Fadel, HE | 1 |
Northrop, G | 1 |
Misenhimer, HR | 1 |
Harp, RJ | 1 |
Wilkinson, PR | 1 |
Issler, H | 1 |
Hesp, R | 1 |
Raftery, EB | 1 |
Bravo, EL | 1 |
Tarazi, RC | 1 |
Dustan, HP | 1 |
Lewis, JW | 1 |
Messerli, FH | 1 |
Frohlich, ED | 1 |
Duke, M | 1 |
Hoffbrand, BI | 1 |
Edmonds, CJ | 1 |
Smith, T | 1 |
Valmin, K | 1 |
Hansen, T | 1 |
Bernardi, P | 1 |
Descovich, GC | 1 |
Rondina, M | 1 |
Pecoraro, F | 1 |
Lenzi, S | 1 |
Shul'tsev, GP | 2 |
Tsalenchuk, IaP | 2 |
Gilunova, NI | 1 |
Lowder, SC | 1 |
Brown, RD | 1 |
Carballo, AS | 1 |
Carney, S | 1 |
Morgan, T | 1 |
Wilson, M | 1 |
Matthews, G | 1 |
Roberts, R | 1 |
Cope, CL | 1 |
Loizou, S | 1 |
Izzard, AS | 1 |
Cragoe, EJ | 1 |
Heagerty, AM | 1 |
Syme, PD | 1 |
Aronson, JK | 1 |
Thompson, CH | 1 |
Williams, EM | 1 |
Green, Y | 1 |
Radda, GK | 1 |
Semplicini, A | 1 |
Ceolotto, G | 1 |
Marzola, M | 1 |
Inagaki, Y | 1 |
Amano, I | 1 |
Overlack, A | 1 |
Conrad, H | 1 |
Stumpe, KO | 1 |
Karniski, LP | 1 |
Luft, FC | 1 |
Zemel, MB | 1 |
Sowers, JA | 1 |
Fineberg, NS | 1 |
Weinberger, MH | 1 |
Soppi, E | 1 |
Viikari, J | 1 |
Seppälä, P | 1 |
Lehtonen, A | 1 |
Saarinen, R | 1 |
Miilunpalo, S | 1 |
Huidobro, F | 1 |
Videla, C | 1 |
Hernández, G | 1 |
Torres, H | 1 |
Jimenez, R | 1 |
Pérez, H | 1 |
Díaz, RA | 1 |
Johnson, BE | 1 |
Mehmel, HC | 1 |
Gordon, RD | 2 |
Zicha, J | 1 |
Kunes, J | 1 |
Jelínek, J | 1 |
Leont'eva, GR | 1 |
Govyrin, VA | 1 |
Withington, PS | 1 |
Durcan, JJ | 1 |
Weir, I | 1 |
Innis, R | 1 |
Savage, T | 1 |
Teschner, M | 1 |
Bahner, U | 1 |
Schaefer, RM | 1 |
Möslein, J | 1 |
Heidland, A | 1 |
Lucas, PA | 3 |
Lacour, B | 3 |
Comte, L | 2 |
McCarron, DA | 2 |
Drüeke, T | 3 |
Gierada, DS | 1 |
Bohr, DF | 1 |
Funder, J | 1 |
Sundar, S | 1 |
Sachdev, KK | 1 |
Vaish, SK | 1 |
Bhattacharya, SK | 1 |
Singh, VP | 1 |
Agarwal, SK | 1 |
Patton, RD | 1 |
Berkowitz, R | 1 |
Buchwald, RP | 1 |
Stein, E | 1 |
Pannier, JL | 1 |
Leusen, I | 1 |
Materson, BJ | 1 |
Oster, JR | 1 |
Perez-Stable, EC | 1 |
Maxwell, MH | 1 |
Miyazawa, T | 1 |
Zakharchenko, VN | 1 |
Dobrova, AS | 1 |
Kunau, RT | 1 |
Webb, HL | 1 |
Borman, SC | 1 |
Vohra, J | 1 |
Burrows, GD | 1 |
Logan, DA | 1 |
Howie, HB | 1 |
Crawford, J | 1 |
Kalinovskaia, IIa | 1 |
Kremer, D | 1 |
Brown, JJ | 2 |
Lever, AF | 2 |
Davies, DL | 1 |
Robertson, JI | 2 |
McConnell, SD | 1 |
Henkin, RI | 1 |
Fodor, JG | 1 |
Pfeiffer, CJ | 1 |
Papezik, VS | 1 |
Brunner, HR | 1 |
Sealey, JE | 1 |
Laragh, JH | 1 |
Degnbol, B | 1 |
Dorph, S | 1 |
Marner, T | 1 |
Lieberman, E | 1 |
Bergström, J | 1 |
Hultman, E | 1 |
Solheim, SB | 1 |
Gundersen, HJ | 1 |
Vohra, JK | 1 |
Aitchison, J | 1 |
Ferriss, JB | 1 |
Kay, AW | 1 |
Neville, AM | 1 |
Symington, T | 1 |
Hagge, W | 1 |
Winegrad, AI | 1 |
Clements, RS | 1 |
Fish, SA | 1 |
Morrison, JC | 1 |
Bucovaz, ET | 1 |
Wiser, WL | 1 |
Whybrew, WD | 1 |
King, JF | 1 |
Easton, R | 1 |
Dunn, M | 1 |
Paulson, OB | 1 |
Olesen, J | 1 |
Christensen, MS | 1 |
Morton, WE | 1 |
Salako, LA | 1 |
Geddes, RA | 1 |
Pawsey, CG | 1 |
O'Halloran, MW | 1 |
Blair-West, JR | 1 |
Coghlan, JP | 1 |
Denton, DA | 1 |
Funder, JW | 1 |
Nelson, J | 1 |
Scoggins, BA | 1 |
Wright, RD | 1 |
Ackerman, GL | 1 |
Paterson, JW | 1 |
Dollery, CT | 1 |
Haslam, RM | 1 |
Gordon, E | 1 |
Rossanda, M | 1 |
Takekoshi, N | 1 |
Retan, JW | 1 |
Dillon, HC | 1 |
Quellhorst, E | 1 |
Scheler, F | 1 |
Arnold, JE | 1 |
Healy, JK | 1 |
Hausmann, W | 1 |
Tárnoky, AL | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Systolic Blood Pressure Intervention Trial[NCT01206062] | 9,361 participants (Actual) | Interventional | 2010-10-31 | Completed | |||
Development of a Mathematical Model for the Evaluation of the Potassium Kinetic During and After Hemodialysis for the Potassium Profiling in the Dialysate to Prevent Arrhythmias[NCT04563091] | 6 participants (Anticipated) | Interventional | 2018-11-15 | Recruiting | |||
Sleepiness and Tiredness Among Doctors Working In A Tertiary Hospital: Is it Work Related or Is There Underlying Sleep Disorders[NCT04020991] | 203 participants (Actual) | Observational | 2018-10-01 | Completed | |||
Efficiency of Speech Therapy in Resistant Hypertensive Patients With Mild Obstructive Sleep Apnea Syndrome[NCT03753633] | 50 participants (Anticipated) | Interventional | 2017-10-01 | Active, not recruiting | |||
Investigating the Effects of Wearing Compression Stockings to Improve Asthma Symptoms at Night[NCT03303586] | 40 participants (Anticipated) | Interventional | 2017-02-21 | Recruiting | |||
Piloting an Adaption of Cognitive Behavioral Therapy for Insomnia for Shift Workers (CBTI-Shift)[NCT05965609] | 60 participants (Anticipated) | Interventional | 2023-12-08 | Recruiting | |||
Impact of Dexmedetomidine Supplemented Analgesia on Sleep Quality in Patients at High-risk of Obstructive Sleep Apnea After Major Surgery: A Randomized, Double-blind, and Placebo-controlled Pilot Study[NCT04608331] | Phase 4 | 152 participants (Actual) | Interventional | 2021-01-29 | Completed | ||
Value of Liquid Potassium Magnesium Citrate in Controlling Hypertension[NCT02653560] | Phase 4 | 30 participants (Actual) | Interventional | 2012-09-30 | Completed | ||
Randomized Trial of Sodium Bicarbonate in Renal Transplant Recipients With Low-normal Serum Bicarbonate Levels[NCT01225796] | Early Phase 1 | 29 participants (Actual) | Interventional | 2010-11-30 | Completed | ||
Alkaline Diet for Insulin Sensitivity[NCT02501343] | 32 participants (Actual) | Interventional | 2015-03-31 | Completed | |||
Haemodynamic Consequences of Changing Potassium Concentrations in Haemodialysis Fluids[NCT01224314] | 24 participants (Actual) | Interventional | 2007-09-30 | Completed | |||
Clinical Significance of Heterozygosity for Mutations of the SLC12A3 Gene Coding for the Thiazide Sensitive Na-Cl Cotransporter[NCT02035046] | 250 participants (Anticipated) | Interventional | 2013-12-31 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
(NCT01206062)
Timeframe: 6 years
Intervention | Participants (Count of Participants) |
---|---|
Intensive Control of SBP | 10 |
Standard Control of SBP | 12 |
(NCT01206062)
Timeframe: 6 years
Intervention | Participants (Count of Participants) |
---|---|
Intensive Control of SBP | 155 |
Standard Control of SBP | 210 |
(NCT01206062)
Timeframe: 6 years
Intervention | Participants (Count of Participants) |
---|---|
Intensive Control of SBP | 243 |
Standard Control of SBP | 319 |
A 3-step process was used ascertain incident cases of all-cause dementia. First, to identify possible cases of dementia a brief Cognition Screening Battery was administered to all participants. Participants who score below the pre-designated screening cut-point for possible cognitive impairment during follow-up were administered a more comprehensive and detailed neurocognitive test battery (the Extended Cognitive Assessment Battery) plus the Functional Assessment Questionnaire (FAQ) which assesses impairments in daily living skills as a result of cognitive impairments. Last, all the above available tests and questionnaire data were submitted to a centralized, web-based system for adjudication by a panel of dementia experts who assigned final study classifications of probable dementia (PD), mild cognitive impairment (MCI) or no impairment (NI). (NCT01206062)
Timeframe: 6 years
Intervention | Participants (Count of Participants) |
---|---|
Intensive Control of SBP | 149 |
Standard Control of SBP | 176 |
(NCT01206062)
Timeframe: 6 years
Intervention | Participants (Count of Participants) |
---|---|
Intensive Control of SBP | 12 |
Standard Control of SBP | 8 |
"Change over 4 years in total white matter lesion volume from baseline Change over 4 years in total brain volume from baseline~Because of the skewed distribution for WML volume, we first applied an inverse hyperbolic sine transformation (asinh), which is similar to a log transformation but can accommodate values of zero. Linear mixed models, including random effects for participant and MRI facility, were used to estimate the change in WML volume and TBV between the treatment groups, including time since randomization (in days) and intracranial volume as covariates. Because the inverse hyperbolic sine transformation is nonlinear, and given the context of a mixed-effects model, back-transformation to the original scale of cm3 is difficult" (NCT01206062)
Timeframe: 4 years
Intervention | asinh(cm3) (Mean) | |
---|---|---|
Change in total white matter lesion volume from ba | Change in total brain volume from baseline | |
Intensive Control of SBP | 0.23 | -7.7 |
Standard Control of SBP | 0.37 | -6.8 |
Systolic blood pressure was measured through an ambulatory blood pressure monitoring device worn by each participant for 24 hours after completing each treatment phase. This devise measures blood pressure intermittently throughout the day and night and provides the average of all readings. (NCT02653560)
Timeframe: 4 weeks
Intervention | mmHg (Mean) |
---|---|
Potassium Magnesium Citrate (KMgCit) Arm | 127 |
Potassium Citrate Arm | 127 |
Potassium Chloride Arm | 126 |
Placebo | 129 |
20 reviews available for hydrogen carbonate and Blood Pressure, High
Article | Year |
---|---|
Dialysate and serum potassium in hemodialysis.
Topics: Aged; Arrhythmias, Cardiac; Azithromycin; Bicarbonates; Black or African American; Calcium; Coronary | 2015 |
Established and Emerging Strategies in the Treatment of Chronic Kidney Disease.
Topics: Allopurinol; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bicarbonate | 2016 |
Knockout mouse models for intestinal electrolyte transporters and regulatory PDZ adaptors: new insights into cystic fibrosis, secretory diarrhoea and fructose-induced hypertension.
Topics: Animals; Bicarbonates; Biological Transport; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conducta | 2009 |
Diet-induced metabolic acidosis.
Topics: Acid-Base Equilibrium; Acidosis; Bicarbonates; Biomarkers; Cardiovascular Diseases; Citric Acid; Die | 2011 |
Volume control in peritoneal dialysis patients: role of new dialysis solutions.
Topics: Acidosis; Bicarbonates; Blood Volume; Double-Blind Method; Glucans; Glucose; Glycation End Products, | 2004 |
Pathophysiology of the syndrome of hyporeninemic hypoaldosteronism.
Topics: Acidosis; Aged; Aldosterone; Ammonia; Angiotensin II; Bicarbonates; Cations, Monovalent; Extracellul | 1980 |
Acid-base status and intracellular pH regulation in lymphocytes from rats with genetic hypertension.
Topics: Acid-Base Equilibrium; Animals; Bicarbonates; Carbon Dioxide; Chlorides; Hydrogen-Ion Concentration; | 1994 |
Alterations in sodium metabolism as an etiological model for hypertension.
Topics: Antiporters; Bicarbonates; Blood Pressure; Calcium; Chlorides; Erythrocytes; Humans; Hypertension; I | 1995 |
Differing effects of supplemental KCl and KHCO3: pathophysiological and clinical implications.
Topics: Adult; Animals; Bicarbonates; Child; Child, Preschool; Dietary Supplements; Humans; Hypertension; Mi | 1999 |
Dynamic interactions between integrative physiology and molecular medicine: the key to understand the mechanism of action of aldosterone in the kidney.
Topics: Acid-Base Equilibrium; Aldosterone; Animals; Bicarbonates; Humans; Hypertension; Kidney; Sodium Chlo | 2000 |
Roles of prostanoids revealed from studies using mice lacking specific prostanoid receptors.
Topics: Animals; Asthma; Bicarbonates; Colonic Neoplasms; Dinoprost; Dinoprostone; Female; Fever; Hypertensi | 2000 |
Chloride in smooth muscle.
Topics: Animals; Bicarbonates; Biophysical Phenomena; Biophysics; Carrier Proteins; Chlorides; Energy Metabo | 2000 |
Metabolic alkalosis.
Topics: Alkalosis; Bicarbonates; Chlorides; Diuretics; Glomerular Filtration Rate; Humans; Hydrochloric Acid | 2001 |
High blood pressure. A side effect of drugs, poisons, and food.
Topics: Androgens; Anesthetics; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Antihypertensive | 1979 |
Current drug therapy - thiazide diuretics.
Topics: Antihypertensive Agents; Benzothiadiazines; Bicarbonates; Chemical Phenomena; Chemistry; Chlorides; | 1975 |
[Erythrocyte Na+/H+ exchange and arterial hypertension].
Topics: Bicarbonates; Biochemical Phenomena; Biochemistry; Electrochemistry; Erythrocytes; Humans; Hydrogen; | 1991 |
Regulation of intracellular pH and its role in vascular smooth muscle function.
Topics: Animals; Bicarbonates; Calcium; Cell Division; Cricetinae; Guinea Pigs; Hydrogen-Ion Concentration; | 1990 |
Syndrome of hypertension and hyperkalemia with normal glomerular filtration rate.
Topics: Adolescent; Adult; Aldosterone; Bicarbonates; Blood Pressure; Child; Diet, Sodium-Restricted; Diuret | 1986 |
[Vertigo].
Topics: Acute Disease; Age Factors; Aortic Valve Insufficiency; Arteriosclerosis; Atropine; Atropine Derivat | 1974 |
Diabetic ketoacidosis.
Topics: Acute Kidney Injury; Bicarbonates; Brain Edema; Diabetic Ketoacidosis; Humans; Hypertension; Insulin | 1971 |
17 trials available for hydrogen carbonate and Blood Pressure, High
Article | Year |
---|---|
Serum bicarbonate and cardiovascular events in hypertensive adults: results from the Systolic Blood Pressure Intervention Trial.
Topics: Aged; Bicarbonates; Biomarkers; Cardiovascular Diseases; Female; Humans; Hypertension; Incidence; Ma | 2020 |
Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy.
Topics: Adult; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitor | 2009 |
Effects of potassium chloride and potassium bicarbonate on endothelial function, cardiovascular risk factors, and bone turnover in mild hypertensives.
Topics: Adult; Albuminuria; Bicarbonates; Blood Pressure; Bone Remodeling; Brachial Artery; Calcium; Cross-O | 2010 |
Higher serum bicarbonate levels within the normal range are associated with better survival and renal outcomes in African Americans.
Topics: Adult; Aged; Antihypertensive Agents; Bicarbonates; Biomarkers; Black or African American; Chronic D | 2011 |
Estimated net endogenous acid production and serum bicarbonate in African Americans with chronic kidney disease.
Topics: Acidosis; Adult; Aged; Bicarbonates; Black or African American; Chi-Square Distribution; Chronic Dis | 2011 |
Response of thiazide-induced hypokalemia to amiloride.
Topics: Aldosterone; Amiloride; Bicarbonates; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypert | 1983 |
Renal acid-base excretion in normotensive salt-sensitive humans.
Topics: Acid-Base Equilibrium; Adult; Ammonium Chloride; Analysis of Variance; Bicarbonates; Blood Pressure; | 1993 |
[Evaluation of fetal condition in pregnancy complicated by hypertension--biochemical assessment of amniotic fluid. III. Acid-base balance].
Topics: Acid-Base Equilibrium; Adult; Amniotic Fluid; Bicarbonates; Carbon Dioxide; Female; Humans; Hydrogen | 1996 |
Spironolactone in essential hypertension: evidence against its effect through mineralocorticoid antagonism.
Topics: Adult; Bicarbonates; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertension; Male; M | 1976 |
Treatment of benign essential hypertension: comparison of furosemide and hydrochlorothiazide.
Topics: Adult; Bicarbonates; Blood Pressure; Body Weight; Clinical Trials as Topic; Diuresis; Dose-Response | 1975 |
The influence of oral potassium citrate/bicarbonate on blood pressure in essential hypertension during unrestricted salt intake.
Topics: Adult; Aldosterone; Bicarbonates; Blood Pressure; Citrates; Female; Humans; Hypertension; Male; Midd | 1991 |
Sodium bicarbonate and sodium chloride: effects on blood pressure and electrolyte homeostasis in normal and hypertensive man.
Topics: Adult; Bicarbonates; Blood Pressure; Female; Humans; Hypertension; Male; Mineral Waters; Randomized | 1990 |
Haemodynamic and metabolic effects of prophylactic nitroglycerin infusion in the immediate period following coronary artery bypass grafting.
Topics: Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Coronary Artery Bypass; Female; Hemodynamics | 1988 |
Potassium supplementation in essential hypertension--a double blind placebo controlled study.
Topics: Bicarbonates; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Humans; Hypertension | 1985 |
Antihypertensive effects of metolazone (zaroxolyn).
Topics: Adult; Aged; Antihypertensive Agents; Bicarbonates; Blood Glucose; Blood Pressure; Blood Urea Nitrog | 1974 |
The effect of different diuretics on elevated blood pressure and serum potassium.
Topics: Adult; Aged; Amides; Bicarbonates; Blood Pressure; Chlorides; Clopamide; Creatinine; Depression, Che | 1973 |
Amiloride hydrochloride in hypertensive patients.
Topics: Bicarbonates; Blood Pressure; Chlorides; Depression, Chemical; Diuretics; Drug Synergism; Guanidines | 1968 |
111 other studies available for hydrogen carbonate and Blood Pressure, High
Article | Year |
---|---|
miRNA-23a modulates sodium-hydrogen exchanger 1 expression: studies in medullary thick ascending limb of salt-induced hypertensive rats.
Topics: Animals; Bicarbonates; Essential Hypertension; Humans; Hypertension; Kidney Medulla; MicroRNAs; Rats | 2023 |
Demographic and clinical profile of black patients with chronic kidney disease attending a tertiary hospital in Johannesburg, South Africa.
Topics: Acidosis; Aged; Allopurinol; Anemia; Bicarbonates; Cross-Sectional Studies; Diabetes Mellitus; Doxaz | 2022 |
Serum bicarbonate as a cardiovascular risk factor: evolving from 'non-traditional'?
Topics: Adult; Bicarbonates; Blood Pressure; Cardiovascular Diseases; Humans; Hypertension; Risk Factors | 2020 |
Independent associations between arterial bicarbonate, apnea severity and hypertension in obstructive sleep apnea.
Topics: Adult; Bicarbonates; Blood Gas Analysis; Cohort Studies; Female; Humans; Hypertension; Male; Middle | 2017 |
Identification of SLC26A transporters involved in the Cl⁻/HCO₃⁻ exchange in proximal tubular cells from WKY and SHR.
Topics: Animals; Antiporters; Bicarbonates; Biological Transport; Cells, Cultured; Chloride-Bicarbonate Anti | 2013 |
Plasma bicarbonate and odds of incident hypertension.
Topics: Adult; Bicarbonates; Biomarkers; Boston; Buffers; Case-Control Studies; Female; Follow-Up Studies; H | 2013 |
Reduced sarcolemmal expression and function of the NBCe1 isoform of the Na⁺-HCO₃⁻ cotransporter in hypertrophied cardiomyocytes of spontaneously hypertensive rats: role of the renin-angiotensin system.
Topics: Ammonium Compounds; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensi | 2014 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni | 2016 |
Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats.
Topics: Acidosis; Animals; Bicarbonates; Biomarkers; Creatinine; DNA (Cytosine-5-)-Methyltransferase 1; DNA | 2016 |
Serum Bicarbonate Is Associated with Heart Failure in the Multi-Ethnic Study of Atherosclerosis.
Topics: Aged; Antihypertensive Agents; Atherosclerosis; Bicarbonates; Blood Pressure; Creatinine; Diuretics; | 2017 |
Posttranslational mechanisms associated with reduced NHE3 activity in adult vs. young prehypertensive SHR.
Topics: Absorption; Aging; Animals; Bicarbonates; Blood Pressure; Dipeptidyl Peptidase 4; Disease Models, An | 2010 |
High prevalence of liddle syndrome phenotype among hypertensive US Veterans in Northwest Louisiana.
Topics: Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Bicarbonates; Blood Pressure; Cross-S | 2010 |
In vivo alterations in cardiac metabolism and function in the spontaneously hypertensive rat heart.
Topics: Adenosine Triphosphate; Animals; Bicarbonates; Carbon Dioxide; Cardiomegaly; Citric Acid Cycle; Hydr | 2012 |
Risk factors for hospital death of patients with end-stage renal disease without previous diagnosis of severe chronic renal failure arriving in an emergency situation at the hospital.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Bicarbonates; Biomarkers; Brazil; Child; Cr | 2003 |
[TREATMENT OF URIC LITHIASIS].
Topics: Bicarbonates; Calcium Metabolism Disorders; Citrates; Diet; Diet Therapy; Diuresis; Gout; Humans; Hy | 1963 |
FURTHER OBSERVATIONS ON THE RENAL PRODUCTION OF ACID IN UREMIA.
Topics: Acids; Ammonium Compounds; Bicarbonates; Blood Chemical Analysis; Carbon Dioxide; Chlorides; Creatin | 1964 |
POLYTHIAZIDE IN THE MANAGEMENT OF HYPERTENSIVE DISEASE. I. EFFECTS OF WATER AND ELECTROLYTE METABOLISM.
Topics: Benzothiadiazines; Bicarbonates; Biomedical Research; Blood Chemical Analysis; Blood Pressure; Blood | 1964 |
[TRICHLORMETHIAZIDE (FLUITRAN) AS A DIURETIC].
Topics: Bicarbonates; Blood Chemical Analysis; Chlorides; Chlorothiazide; Creatine; Creatinine; Diuretics; E | 1964 |
[TRICHLORMETHIAZIDE (FLUITRAN) AS A HYPOTENSIVE AGENT].
Topics: Antihypertensive Agents; Bicarbonates; Blood Chemical Analysis; Blood Pressure Determination; Chlori | 1964 |
TREATMENT OF CHRONIC RENAL FAILURE.
Topics: Acidosis; Anemia; Anti-Bacterial Agents; Bicarbonates; Chloramphenicol; Classification; Diet; Diet T | 1964 |
A COMPARATIVE STUDY OF THE DIURETICS CHLORTHALIDONUM AND CYCLOPENTHIAZIDUM.
Topics: Benzothiadiazines; Bicarbonates; Biomedical Research; Blood; Chlorides; Chlorthalidone; Diet, Sodium | 1964 |
EFFECTS OF ACIDOSIS ON RESPIRATORY FUNCTION.
Topics: Acidosis; Bicarbonates; Carbon Dioxide; Hemoglobins; Hydrochloric Acid; Hypertension; Hypertension, | 1965 |
METABOLIC ALTERATIONS NOTED IN CYANOTIC AND ACYANOTIC INFANTS DURING OPERATION UNDER HYPERBARIC CONDITIONS.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Aortic Coarctation; Aortic Valve Stenosis; A | 1965 |
Effects of adrenalectomy, desoxycorticosterone acetate and increased fluid intake on intake of sodium chloride and bicarbonate by hypertensive and normal rats.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Animals; Bicarbonates; Blood Pressure; Blood Pressure Determ | 1951 |
[Clinical experiences with TEAB (tetraethylammonium bromide SPOFA)].
Topics: Bicarbonates; Blood Pressure; Blood Vessels; Hypertension; Tetraethylammonium | 1951 |
Impaired 11-beta hydroxysteroid dehydrogenase type 2 activity in sweat gland ducts in human essential hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenal Cortex Hormones; Adult; Aldosterone; Bicarbonat | 2004 |
Chloride-dominant salt sensitivity in the stroke-prone spontaneously hypertensive rat.
Topics: Animals; Bicarbonates; Blood Pressure; Body Weight; Chlorides; Creatinine; Drug Combinations; Electr | 2005 |
Donor characteristics associated with liver graft survival.
Topics: Acidosis; Adolescent; Adult; Aged; Aging; Bicarbonates; Female; Graft Survival; Humans; Hypertension | 2005 |
The renal physiology of pendrin (SLC26A4) and its role in hypertension.
Topics: Absorption; Acid-Base Equilibrium; Aldosterone; Animals; Anion Transport Proteins; Bicarbonates; Blo | 2006 |
Dietary chloride and bicarbonate as determinants of desoxycorticosterone hypertension.
Topics: Animals; Bicarbonates; Blood Pressure; Desoxycorticosterone; Diet; Drug Interactions; Hypertension; | 1984 |
Beta blocker therapy in 125 cases of hypertension during pregnancy.
Topics: Abnormalities, Drug-Induced; Adrenergic beta-Antagonists; Adult; Apgar Score; Bicarbonates; Birth We | 1983 |
Effect of chloride on renin and blood pressure responses to sodium chloride.
Topics: Adult; Animals; Bicarbonates; Blood Pressure; Chlorides; Diet; Dogs; Humans; Hypertension; Male; Nit | 1983 |
[Metabolism of potassium and sodium when administered with different anions to patients with ischemic heart disease and arterial hypertension].
Topics: Bicarbonates; Coronary Disease; Humans; Hypertension; Injections, Intravenous; Potassium; Potassium | 1984 |
Salt-sensitive hypertension: contribution of chloride.
Topics: Animals; Bicarbonates; Blood Pressure; Chlorides; Diet; Hypertension; Kidney; Loop of Henle; Male; P | 1984 |
[Prevention of arterial hypertension sailors].
Topics: Bicarbonates; Humans; Hypertension; Natriuresis; Naval Medicine; Sodium Chloride; USSR | 1981 |
Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients.
Topics: Adult; Aldosterone; Amiloride; Angiotensin II; Bendroflumethiazide; Bicarbonates; Blood Pressure; Di | 1980 |
Hypokalemia during the treatment of arterial hypertension with diuretics.
Topics: Adult; Aged; Bicarbonates; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertens | 1980 |
The regulation of pH in resistance arteries from spontaneously hypertensive and Wistar-Kyoto rats: the effect of bicarbonate.
Topics: Animals; Arteries; Bicarbonates; Hydrogen-Ion Concentration; Hypertension; Male; Rats; Rats, Inbred | 1995 |
pHi regulation in myocardium of the spontaneously hypertensive rat. Compensated enhanced activity of the Na(+)-H+ exchanger.
Topics: Animals; Bicarbonates; Buffers; Chlorides; Data Interpretation, Statistical; Fluorescence; Hydrogen- | 1995 |
Prostaglandin E2 regulation of ion transport is absent in medullary thick ascending limbs from SHR.
Topics: Absorption; Animals; Arginine Vasopressin; Bicarbonates; Biological Transport; Chlorides; Cholera To | 1995 |
Regulation of intracellular pH in the spontaneously hypertensive rat. Role of bicarbonate-dependent transporters.
Topics: Animals; Antiporters; Bicarbonates; Buffers; Carbon Dioxide; Cells, Cultured; Chloride-Bicarbonate A | 1994 |
Potassium preserves endothelial function and enhances aortic compliance in Dahl rats.
Topics: Acetylcholine; Animals; Bicarbonates; Blood Pressure; Compliance; Hypertension; Male; Nitric Oxide; | 1993 |
Hypertension with combined pancreas-kidney transplants in patients with diabetic nephropathy.
Topics: Bicarbonates; Blood Glucose; Blood Pressure; Creatinine; Diabetes Mellitus, Type 1; Diabetic Nephrop | 1993 |
Pathophysiological consequences of changes in the coupling ratio of Na,K-ATPase for renal sodium reabsorption and its implications for hypertension.
Topics: Animals; Bicarbonates; Carrier Proteins; Humans; Hypertension; Kidney; Kidney Tubules, Proximal; Kin | 1996 |
Rhabdomyolysis and acute renal failure associated with gemfibrozil therapy.
Topics: Acute Kidney Injury; Aged; Angiotensin-Converting Enzyme Inhibitors; Bicarbonates; Diabetes Mellitus | 1996 |
Effect of bicarbonate haemodialysis on peripheral oxygen availability in mild hypertensive patients.
Topics: 2,3-Diphosphoglycerate; Arterial Occlusive Diseases; Bicarbonates; Female; Glucosephosphate Dehydrog | 1997 |
Normotensive salt sensitivity: effects of race and dietary potassium.
Topics: Adult; Aged; Bicarbonates; Black People; Blood Pressure; Data Interpretation, Statistical; Humans; H | 1999 |
Risk factors of renal failure progression two years prior to dialysis.
Topics: Anemia; Bicarbonates; Blood Proteins; Calcium; Cholesterol; Creatinine; Diabetic Nephropathies; Dise | 1999 |
[What is Na+/H+ exchanger guilty of in cardiology?].
Topics: Acidosis; Angiotensin II; Animals; Bicarbonates; Calcium; Carbon Dioxide; Cell Membrane Permeability | 2000 |
Chloride-sensitive renal microangiopathy in the stroke-prone spontaneously hypertensive rat.
Topics: Animals; Bicarbonates; Blood Pressure; Chlorides; Creatinine; Disease Susceptibility; Hypertension; | 2001 |
Mutations in the Na-Cl cotransporter reduce blood pressure in humans.
Topics: Alkalosis; Bicarbonates; Blood Pressure; Calcium; Carrier Proteins; Founder Effect; Genotype; Hetero | 2001 |
Initial potassium loss and hypokalaemia during chlorthalidone administration in patients with essential hypertension: the influence of dietary sodium restriction.
Topics: Adult; Bicarbonates; Chlorides; Chlorthalidone; Diet, Sodium-Restricted; Female; Humans; Hydrogen-Io | 1978 |
Acid base balance in pre-eclamptic, hypertensive and diabetic pregnancies. Maternal blood and amniotic fluid studies.
Topics: Acid-Base Equilibrium; Adult; Amniotic Fluid; Bicarbonates; Carbon Dioxide; Female; Humans; Hydrogen | 1979 |
Total body and serum potassium during prolonged thiazide therapy for essential hypertension.
Topics: Bendroflumethiazide; Bicarbonates; Blood Pressure; Blood Pressure Determination; Humans; Hypertensio | 1975 |
Dissociation between renin and arterial pressure responses to beta-adrenergic blockade in human essential hypertension.
Topics: Adrenergic beta-Antagonists; Bicarbonates; Blood Pressure; Chlorides; Creatinine; Diuretics; Drug Ad | 1975 |
Thiazide-induced hypokalemia. Association with acute myocardial infarction and ventricular fibrillation.
Topics: Acute Disease; Aged; Benzothiadiazines; Bicarbonates; Diuretics; Female; Humans; Hypertension; Hypok | 1978 |
[Renal control of acid-base equilibrium during dyslipidemia].
Topics: Acid-Base Equilibrium; Adolescent; Adult; Aged; Bicarbonates; Child; Female; Humans; Hyperlipidemias | 1977 |
[Comparative evaluation of the saluretic effect of furosemide, sodium bicarbonate and heparin].
Topics: Bicarbonates; Drug Evaluation; Furosemide; Glomerulonephritis; Heparin; Humans; Hypertension; Natriu | 1976 |
Hypertension corrected by discontinuing chronic sodium bicarbonate ingestion. Subsequent transient hypoaldosteronism.
Topics: 17-Hydroxycorticosteroids; Aldosterone; Angiotensin II; Antihypertensive Agents; Bicarbonates; Calci | 1975 |
Aborted malignant hyperthermia: case report.
Topics: Acidosis; Adult; Anesthesia, General; Aspartate Aminotransferases; Bicarbonates; Creatine Kinase; Fe | 1975 |
Sodium restriction and thiazide diuretics in the treatment of hypertension.
Topics: Amiloride; Bicarbonates; Body Weight; Chlorothiazide; Diet, Sodium-Restricted; Diuretics; Humans; Hy | 1975 |
Deoxycorticosterone excretion in normal, hypertensive and hypokalaemic subjects.
Topics: Aldosterone; Animals; Bicarbonates; Blood Pressure; Cross Reactions; Desoxycorticosterone; Humans; H | 1975 |
Intracellular pH in human resistance arteries in essential hypertension.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo | 1991 |
Na+/H+ and HCO3-/Cl- exchange in the control of intracellular pH in vivo in the spontaneously hypertensive rat.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo | 1991 |
[Bicarbonate dialysate].
Topics: Acetates; Acetic Acid; Adult; Aged; Aged, 80 and over; Bicarbonates; Buffers; Calcium Carbonate; Che | 1991 |
Abnormal acid-base regulation in salt-sensitive normotensive man.
Topics: Acid-Base Imbalance; Acidosis; Adult; Animals; Bicarbonates; Blood Pressure; Humans; Hydrogen-Ion Co | 1991 |
Potential role of Cl-HCO3 exchange in regulating vascular tone.
Topics: Animals; Bicarbonates; Biological Transport; Carbon Dioxide; Carrier Proteins; Chloride-Bicarbonate | 1990 |
Unusual association of hyperkalemia and hypertension.
Topics: Adult; Aldosterone; Bicarbonates; Erythrocytes; Female; Humans; Hyperkalemia; Hypertension; Ion Chan | 1986 |
[Lactic acidosis in diabetic patients associated with buformin].
Topics: Acidosis, Lactic; Aged; Bicarbonates; Biguanides; Buformin; Diabetes Mellitus; Diabetic Angiopathies | 1989 |
Resistant hypertension due to pica (baking soda)
Topics: Adult; Anemia, Hypochromic; Bicarbonates; Female; Humans; Hypertension; Patient Compliance; Pica; So | 1989 |
[Therapy of acute myocardial infarct].
Topics: Acidosis; Analgesics; Atropine; Bicarbonates; Bradycardia; Cardiac Complexes, Premature; Critical Ca | 1985 |
Dietary chloride as a determinant of disordered calcium metabolism in salt-dependent hypertension.
Topics: Animals; Bicarbonates; Blood Pressure; Body Weight; Calcium; Desoxycorticosterone; Diet; Hypertensio | 1985 |
The importance of sodium and chloride ions for the development of DOCA-NaCl hypertension: a haemodynamic study.
Topics: Animals; Bicarbonates; Chlorides; Desoxycorticosterone; Hemodynamics; Hypertension; Male; Rats; Rats | 1986 |
Early functional effects of various antihypertensive drugs in chronically uremic rats.
Topics: Acidosis; Animals; Antihypertensive Agents; Bicarbonates; Chlorides; Chronic Disease; Creatinine; Hy | 1988 |
Abnormal parameters of acid-base balance in genetic hypertension.
Topics: Acid-Base Equilibrium; Animals; Bicarbonates; Calcium; Hydrogen-Ion Concentration; Hypertension; Mal | 1988 |
The influence of potassium and bicarbonate on red blood cell sodium in the DOCA-hypertensive pig.
Topics: Animals; Bicarbonates; Desoxycorticosterone; Erythrocytes; Female; Hypertension; Potassium; Sodium; | 1988 |
Pathogenesis of abnormal acid-base balance in the young spontaneously hypertensive rat.
Topics: Acidosis; Animals; Bicarbonates; Calcium; Creatinine; Hydrogen-Ion Concentration; Hypertension; Male | 1988 |
Membrane transport pathways and essential hypertension.
Topics: Bicarbonates; Biological Transport, Active; Cell Membrane; Chlorides; Erythrocytes; Humans; Hyperten | 1986 |
Disturbance of acid-base balance in the young spontaneously hypertensive rat.
Topics: Acid-Base Imbalance; Anesthesia, General; Animals; Bicarbonates; Blood Pressure; Calcium; Hydralazin | 1987 |
Hypothermia and profound acidosis due to benign prostatic hyperplasia.
Topics: Acetazolamide; Acidosis; Aged; Bicarbonates; Glaucoma; Hot Temperature; Humans; Hypertension; Hypoth | 1971 |
Proceedings: Influence of changes in the acid-base balance on cerebral blood flow after an actue hypertensive insult.
Topics: Animals; Bicarbonates; Blood-Brain Barrier; Brain; Carbon Dioxide; Cats; Cerebrovascular Circulation | 1974 |
[Sodium and arterial hypertension].
Topics: Animals; Arteries; Bicarbonates; Biological Transport; Cardiac Output; Cell Membrane Permeability; C | 1969 |
[Clinical pathophysiological study of venous blood gas partial pressures and pH of organs in various diseases (author's transl)].
Topics: Adolescent; Adult; Bicarbonates; Brain; Carbon Dioxide; Cerebrovascular Circulation; Chronic Disease | 1974 |
[Use of sodium hydrocarbonate in hypertensive disease and renal hypertension].
Topics: Adolescent; Antihypertensive Agents; Bicarbonates; Drug Therapy, Combination; Humans; Hydrocarbons; | 1974 |
Characteristics of sodium reabsorption in the loop of Henle and distal tubule.
Topics: Animals; Aorta; Bicarbonates; Biological Transport; Blood Pressure; Blood Volume; Constriction; Extr | 1974 |
Cardiovascular complications of tricyclic antidepressant overdosage.
Topics: Antidepressive Agents; Arrhythmias, Cardiac; Bicarbonates; Cardiovascular Diseases; Electrocardiogra | 1974 |
Anaesthesia and renal transplantation: an analysis of fifty-six cases.
Topics: Adolescent; Adult; Anesthesia, General; Atropine; Bicarbonates; Chlorides; Female; Hematocrit; Hemog | 1974 |
Amiloride in primary hyperaldosteronism with chronic peptic ulceration.
Topics: Aged; Amiloride; Bicarbonates; Blood Pressure; Body Water; Chlorides; Chronic Disease; Diuretics; Fe | 1973 |
Increased preference for Na + and K + salts in spontaneously hypertensive (SH) rats.
Topics: Animals; Bicarbonates; Chlorides; Feeding Behavior; Hypertension; Male; Potassium; Rats; Rats, Inbre | 1973 |
Relationship of drinking water quality (hardness-softness) to cardiovascular mortality in Newfoundland.
Topics: Adult; Aged; Bicarbonates; Calcium; Cardiovascular Diseases; Chlorides; Female; Heart; Humans; Hyper | 1973 |
Renin subgroups in essential hypertension. Further analysis of their pathophysiological and epidemiological characteristics.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aldosterone; Bicarbonates; Blood Urea Nitrogen; Diet | 1973 |
Management of acute renal failure in infants and children.
Topics: Acidosis; Acute Kidney Injury; Anemia; Bicarbonates; Calcium; Child, Preschool; Dehydration; Furosem | 1973 |
The effect of mefruside on plasma and muscle electrolytes and blood pressure in normal subjects and in patients with essential hypertension.
Topics: Adult; Aged; Bicarbonates; Blood; Blood Glucose; Blood Pressure; Blood Proteins; Body Water; Body We | 1973 |
Peripheral blood flow and metabolic control in juvenile diabetes.
Topics: Adipose Tissue; Adolescent; Adult; Bicarbonates; Blood Flow Velocity; Blood Glucose; Diabetes Compli | 1974 |
Cardiovascular abnormalities following tricyclic antidepressant drug overdosage.
Topics: Acidosis; Antidepressive Agents; Arrhythmias, Cardiac; Bicarbonates; Bradycardia; Heart Rate; Humans | 1974 |
Quadric analysis in the preoperative distinction between patients with and without adrenocortical tumors in hypertension with aldosterone excess and low plasma renin.
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adult; Aldosterone; Bicarbonates; Blood Pr | 1971 |
[Treatment of acute glomerulonephritis].
Topics: Acute Disease; Anuria; Bicarbonates; Brain Diseases; Child; Child, Preschool; Diet Therapy; Glomerul | 1970 |
Cerebral spinal fluid studies in eclampsia.
Topics: Bicarbonates; Cerebrospinal Fluid; Chlorides; Eclampsia; Female; Hematocrit; Humans; Hypertension; N | 1972 |
Acute pernicious beriberi heart disease.
Topics: Acidosis; Acute Disease; Adult; Alcoholism; Beriberi; Bicarbonates; Cardiac Output; Cardiomyopathies | 1972 |
Restoration of autoregulation of cerebral blood flow by hypocapnia.
Topics: Aged; Bicarbonates; Blood Pressure; Brain Neoplasms; Carbon Dioxide; Cerebrovascular Circulation; Ce | 1972 |
Hypertension and drinking water. A pilot statewide ecological study in Colorado.
Topics: Adult; Bicarbonates; Chlorides; Colorado; Geography; Humans; Hypertension; Iron; Magnesium; Male; Mi | 1971 |
Serum electrolytes in hypertension in Nigerians.
Topics: Adult; Aged; Bicarbonates; Chlorides; Creatinine; Female; Humans; Hypertension; Male; Mathematics; M | 1971 |
Hypertension and severe hyperkalaemia associated with suppression of renin and aldosterone and completely reversed by dietary sodium restriction.
Topics: Aldosterone; Ammonia; Bicarbonates; Blood Urea Nitrogen; Child; Chlorides; Creatinine; Diet, Sodium- | 1970 |
Sodium homeostasis, salt appetite, and hypertension.
Topics: Aldosterone; Animals; Anxiety; Appetite; Bicarbonates; Diet; Diet, Sodium-Restricted; Female; Food A | 1970 |
Increased calcium excretion after saline administration to hypertensive subjects.
Topics: Adult; Bicarbonates; Calcium; Creatinine; Humans; Hypertension; Infusions, Parenteral; Kidney Tubule | 1971 |
The importance of the cerebrospinal fluid acid-base status in the treatment of unconscious patients with brain lesions.
Topics: Acid-Base Equilibrium; Acidosis; Adolescent; Adult; Aged; Bicarbonates; Brain Diseases; Carbon Dioxi | 1968 |
[Studies on hypertension. 2. Influence of acid-base imbalance on the distribution of electrolytes and its relationship to hemodynamics].
Topics: Acid-Base Equilibrium; Acidosis; Adult; Aged; Alkalosis; Arteries; Bicarbonates; Blood Pressure; Chl | 1968 |
Furosemide in the treatment of acute post-streptococcal glomerulonephritis.
Topics: Bicarbonates; Blood Pressure Determination; Blood Urea Nitrogen; Child; Chlorides; Creatinine; Edema | 1969 |
[On the management of renal acidosis using sodium bicarbonate and ethacrynic acid].
Topics: Acidosis, Renal Tubular; Acute Kidney Injury; Adult; Bicarbonates; Blood Pressure; Body Weight; Etha | 1969 |
Hyperkalemia, hypertension and systemic acidosis without renal failure associated with a tubular defect in potassium excretion.
Topics: Acetazolamide; Acidosis, Renal Tubular; Adolescent; Adult; Aminohippuric Acids; Bicarbonates; Blood | 1969 |
Biochemical effects of short-term treatment with carbenoxolone disodium.
Topics: Adolescent; Adult; Aged; Bicarbonates; Digestive System; Female; Gastric Mucosa; Gastrointestinal Di | 1966 |