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hydrogen carbonate and Blood Pressure, High

hydrogen carbonate has been researched along with Blood Pressure, High in 148 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Research Excerpts

ExcerptRelevanceReference
"The effects of amiloride hydrochloride on thiazide-induced hypokalemia were evaluated."9.05Response of thiazide-induced hypokalemia to amiloride. ( Chan, L; Maronde, RF; Milgrom, M; Vlachakis, ND, 1983)
"The effect of a six-week course of spironolactone 300 mg/day was examined in 25 unselected patients with essential hypertension."9.04Spironolactone in essential hypertension: evidence against its effect through mineralocorticoid antagonism. ( Edmonds, CJ; Hoffbrand, BI; Smith, T, 1976)
"In uninephrectomized rats given desoxycorticosterone (DOC) and a fixed amount of dietary sodium, we sought to determine if the anionic component of the sodium salt consumed could be a pathogenetic determinant of the occurrence and maintenance of hypertension."7.67Dietary chloride and bicarbonate as determinants of desoxycorticosterone hypertension. ( Kurtz, TW; Morris, RC, 1984)
"We report two diabetic patients who developed lactic acidosis following the use of Buformin."7.67[Lactic acidosis in diabetic patients associated with buformin]. ( Díaz, RA; Hernández, G; Huidobro, F; Jimenez, R; Pérez, H; Torres, H; Videla, C, 1989)
"Treatment with procainamide not only inhibited the overexpression of DNMT1 but also diminished the overproduction of IL-6 in rhabdomyolysis rats."5.43Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats. ( Chen, SJ; Hii, HP; Ka, SM; Liao, MH; Shih, CC; Tsao, CM; Wu, CC, 2016)
"Chlorthalidone (50 mg daily) was given for 14 days."5.26Initial potassium loss and hypokalaemia during chlorthalidone administration in patients with essential hypertension: the influence of dietary sodium restriction. ( Landmann-Suter, R; Struyvenberg, A, 1978)
" We conducted a double-blind, placebo-controlled trial in 81 patients with diabetes, hypertension, and albuminuria (urine albumin-to-creatinine ratio > or =300 mg/g) who all received lisinopril (80 mg once daily)."5.14Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy. ( Adams-Huet, B; Mehdi, UF; Raskin, P; Toto, RD; Vega, GL, 2009)
"The effects of amiloride hydrochloride on thiazide-induced hypokalemia were evaluated."5.05Response of thiazide-induced hypokalemia to amiloride. ( Chan, L; Maronde, RF; Milgrom, M; Vlachakis, ND, 1983)
"The effect of a six-week course of spironolactone 300 mg/day was examined in 25 unselected patients with essential hypertension."5.04Spironolactone in essential hypertension: evidence against its effect through mineralocorticoid antagonism. ( Edmonds, CJ; Hoffbrand, BI; Smith, T, 1976)
"We used myocytes from Wistar, SHR, losartan-treated SHR (Los-SHR), and Angiotensin II (Ang II)-induced cardiac hypertrophy."3.80Reduced sarcolemmal expression and function of the NBCe1 isoform of the Na⁺-HCO₃⁻ cotransporter in hypertrophied cardiomyocytes of spontaneously hypertensive rats: role of the renin-angiotensin system. ( Aiello, EA; Caldiz, CI; Ciancio, MC; De Giusti, VC; Orlowski, A, 2014)
"In uninephrectomized rats given desoxycorticosterone (DOC) and a fixed amount of dietary sodium, we sought to determine if the anionic component of the sodium salt consumed could be a pathogenetic determinant of the occurrence and maintenance of hypertension."3.67Dietary chloride and bicarbonate as determinants of desoxycorticosterone hypertension. ( Kurtz, TW; Morris, RC, 1984)
"In 116 patients with coronary heart disease, essential hypertension, acute and chronic glomerulonephritis and pyelonephritis, the authors observed differences in the excretion of the ions of 42K, stable potassium, 24Na, stable sodium, chlorine as well as in the value of diuresis during the administration of equimolar solutions of potassium hydrocarbonate and potassium chloride, sodium hydrocarbonate and sodium chloride labeled with 42K and 24Na respectively."3.67[Metabolism of potassium and sodium when administered with different anions to patients with ischemic heart disease and arterial hypertension]. ( Barnatskiĭ, VN; Korsunskiĭ, VN; Moiseev, AA; Stoliarov, VP; Vikhrov, NI, 1984)
"We report two diabetic patients who developed lactic acidosis following the use of Buformin."3.67[Lactic acidosis in diabetic patients associated with buformin]. ( Díaz, RA; Hernández, G; Huidobro, F; Jimenez, R; Pérez, H; Torres, H; Videla, C, 1989)
"In rats given desoxycorticosterone (DOC), the recently reported finding that a normal amount of dietary sodium chloride (NaCl) induces hypertension but an equimolar amount of sodium bicarbonate (NaHCO3) does not, might be a consequence of the differing effects of the two sodium salts on the metabolism of calcium."3.67Dietary chloride as a determinant of disordered calcium metabolism in salt-dependent hypertension. ( Kurtz, TW; Morris, RC, 1985)
"The role of sodium and its accompanying anion for the development of DOCA-salt hypertension was studied in uninephrectomized DOCA-treated weanling Wistar rats which were fed a diet containing either sodium chloride or sodium bicarbonate (170 mmol/kg)."3.67The importance of sodium and chloride ions for the development of DOCA-NaCl hypertension: a haemodynamic study. ( Govyrin, VA; Jelínek, J; Kunes, J; Leont'eva, GR; Zicha, J, 1986)
" Prevention of the development of hypertension in SHR by hydralazine treatment from weaning did not increase pH or bicarbonate compared with untreated SHR, indicating that the metabolic acidosis in the SHR was not a consequence of raised blood pressure."3.67Disturbance of acid-base balance in the young spontaneously hypertensive rat. ( Drüeke, T; Lacour, B; Lucas, PA; McCarron, DA, 1987)
"In a study of 50 patients with uncomplicated arterial hypertension the administration of hydrochlorothiazide, 50 to 100 mg daily or every other day, with or without reserpine, 0."3.66Hypokalemia during the treatment of arterial hypertension with diuretics. ( Beauchemin, M; Gougoux, A; Lemieux, G; Vinay, P, 1980)
"Studies were carried out in 69 patients with essential hypertension to examine the relationship between changes in plasma renin activity (PRA) and arterial pressure (BP) in response to a beta-adrenergic blocking agent, propranolol."3.65Dissociation between renin and arterial pressure responses to beta-adrenergic blockade in human essential hypertension. ( Bravo, EL; Dustan, HP; Lewis, JW; Tarazi, RC, 1975)
"Hypocitraturia and hypercalciuria are risk factors for calcium stone disease."2.47Diet-induced metabolic acidosis. ( Adeva, MM; Souto, G, 2011)
"Metabolic alkalosis is a primary pathophysiologic event characterized by the gain of bicarbonate or the loss of nonvolatile acid from extracellular fluid."2.41Metabolic alkalosis. ( Khanna, A; Kurtzman, NA, 2001)
"Obstructive sleep apnea is characterized by intermittent hypoxia and hypercapnia."1.46Independent associations between arterial bicarbonate, apnea severity and hypertension in obstructive sleep apnea. ( Eskandari, D; Grote, L; Hedner, J; Penzel, T; Schneider, H; Zou, D, 2017)
"Treatment with procainamide not only inhibited the overexpression of DNMT1 but also diminished the overproduction of IL-6 in rhabdomyolysis rats."1.43Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats. ( Chen, SJ; Hii, HP; Ka, SM; Liao, MH; Shih, CC; Tsao, CM; Wu, CC, 2016)
"Many end stage renal disease (ESRD) patients get their first nephrologic care under critical clinical conditions and without previous diagnosis of chronic renal failure (CRF), a situation even worse than the late referral of CRF patients for nephrologic treatment."1.32Risk factors for hospital death of patients with end-stage renal disease without previous diagnosis of severe chronic renal failure arriving in an emergency situation at the hospital. ( Abdulkader, RC; Burdmann, EA; Oliveira, GM; Zanetta, DM, 2003)
"Metabolic acidosis has recently been observed in rat models of salt-sensitive genetic hypertension."1.28Abnormal acid-base regulation in salt-sensitive normotensive man. ( Distler, A; Sharma, AM, 1991)
" In the Sprague-Dawley rat, acute and chronic administration of sodium salts other than sodium chloride failed to suppress plasma renin activity, whereas renin was inhibited by both sodium chloride and by selective chloride (without sodium) loading."1.27Effect of chloride on renin and blood pressure responses to sodium chloride. ( Galla, JH; Kotchen, TA; Luke, RG; Ott, CE; Whitescarver, S, 1983)
"Amiloride was disproportionately potent in lowering serum bicarbonate, and the data do not suggest that these drugs elevate plasma potassium simply by correcting metabolic alkalosis."1.26Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients. ( Fraser, R; Hettiarachchi, J; Morton, JJ; Ramsay, LE, 1980)
"Chlorthalidone (50 mg daily) was given for 14 days."1.26Initial potassium loss and hypokalaemia during chlorthalidone administration in patients with essential hypertension: the influence of dietary sodium restriction. ( Landmann-Suter, R; Struyvenberg, A, 1978)
"If hypokalemia is present in patients receiving thiazides who have had an acute myocardial infarction, it should be corrected so as to remove this predisposing cause of ventricular fibrillation."1.26Thiazide-induced hypokalemia. Association with acute myocardial infarction and ventricular fibrillation. ( Duke, M, 1978)

Research

Studies (148)

TimeframeStudies, this research(%)All Research%
pre-199088 (59.46)18.7374
1990's25 (16.89)18.2507
2000's15 (10.14)29.6817
2010's16 (10.81)24.3611
2020's4 (2.70)2.80

Authors

AuthorsStudies
Lombari, P1
Mallardo, M1
Petrazzuolo, O1
Amruthraj Nagoth, J1
Fiume, G1
Scanni, R1
Iervolino, A1
Damiano, S1
Coppola, A1
Borriello, M1
Ingrosso, D1
Perna, AF1
Zacchia, M1
Trepiccione, F1
Capasso, G1
Meremo, A1
Paget, G1
Duarte, R1
Dickens, C1
Dix-Peek, T1
Bintabara, D1
Naicker, S1
Wesson, DE1
Dobre, M1
Pajewski, NM1
Beddhu, S3
Chonchol, M1
Hostetter, TH1
Li, P1
Rahman, M1
Servilla, K1
Weiner, DE1
Wright, JT1
Raphael, KL2
Eskandari, D1
Zou, D1
Grote, L1
Schneider, H1
Penzel, T1
Hedner, J1
Simão, S1
Gomes, P1
Pinho, MJ1
Soares-da-Silva, P1
Mandel, EI1
Forman, JP1
Curhan, GC1
Taylor, EN1
Orlowski, A1
Ciancio, MC1
Caldiz, CI1
De Giusti, VC1
Aiello, EA1
Hung, AM1
Hakim, RM1
Chung, F1
Abdullah, HR1
Liao, P1
Shih, CC1
Hii, HP1
Tsao, CM1
Chen, SJ1
Ka, SM1
Liao, MH1
Wu, CC1
Pena-Polanco, JE1
Fried, LF1
Kendrick, JB1
Zelnick, L1
Chonchol, MB1
Siscovick, D1
Hoofnagle, AN1
Ix, JH1
Sarnak, M1
Shlipak, MG1
Kestenbaum, B1
de Boer, IH1
Seidler, U1
Singh, A1
Chen, M1
Cinar, A1
Bachmann, O1
Zheng, W1
Wang, J1
Yeruva, S1
Riederer, B1
Mehdi, UF1
Adams-Huet, B1
Raskin, P1
Vega, GL1
Toto, RD1
He, FJ1
Marciniak, M1
Carney, C1
Markandu, ND1
Anand, V1
Fraser, WD1
Dalton, RN1
Kaski, JC1
MacGregor, GA1
Crajoinas, RO1
Lessa, LM1
Carraro-Lacroix, LR1
Davel, AP1
Pacheco, BP1
Rossoni, LV1
Malnic, G1
Girardi, AC1
Wei, G1
Baird, BC1
Greene, T1
Tapolyai, M1
Uysal, A1
Dossabhoy, NR1
Zsom, L1
Szarvas, T1
Lengvárszky, Z1
Fülöp, T1
Adeva, MM1
Souto, G1
Scialla, JJ1
Appel, LJ1
Astor, BC1
Miller, ER1
Woodward, M1
Parekh, RS1
Anderson, CA1
Dodd, MS1
Ball, DR1
Schroeder, MA1
Le Page, LM1
Atherton, HJ1
Heather, LC1
Seymour, AM1
Ashrafian, H1
Watkins, H1
Clarke, K1
Tyler, DJ1
Abdulkader, RC1
Zanetta, DM1
Oliveira, GM1
Burdmann, EA1
THOMAS, J1
THOMAS, E1
BRIGGS, AP1
FINDLEY, T1
HARMS, WS1
TALSO, PJ1
YOUNG, L1
TANSEY, WJ1
WILLUMSEN, J2
CLAUSEN, E1
GALSKOV, A1
SCHREINER, GE1
MEES, EJ1
GEYSKES, GG1
ENSON, Y1
BERHNARD, WF1
DANIS, R1
GROSS, RE1
Lameire, N1
TOSTESON, DC1
DEFRIEZ, AI1
ABRAMS, M1
GOTTSCHALK, CW1
LANDIS, EM1
REISZ, O1
Bocchi, B1
Kenouch, S1
Lamarre-Cliche, M1
Muffat-Joly, M1
Capron, MH1
Fiet, J1
Morineau, G1
Azizi, M1
Bonvalet, JP1
Farman, N1
Schmidlin, O4
Tanaka, M4
Bollen, AW1
Yi, SL2
Morris, RC7
Cuende, N1
Miranda, B1
Cañón, JF1
Garrido, G1
Matesanz, R1
Wall, SM1
Kurtz, TW3
Dubois, D1
Petitcolas, J1
Temperville, B1
Klepper, A1
Catherine, P1
Kotchen, TA2
Luke, RG1
Ott, CE2
Galla, JH1
Whitescarver, S1
Korsunskiĭ, VN1
Moiseev, AA1
Barnatskiĭ, VN3
Stoliarov, VP1
Vikhrov, NI2
Whitescarver, SA1
Jackson, BA1
Guthrie, GP1
Maronde, RF1
Milgrom, M1
Vlachakis, ND1
Chan, L1
Phelps, KR1
Lieberman, RL1
Oh, MS1
Carroll, HJ1
Kotenko, VA1
Goroiaev, BI1
Ramsay, LE1
Hettiarachchi, J1
Fraser, R3
Morton, JJ1
Lemieux, G1
Beauchemin, M1
Vinay, P1
Gougoux, A1
Scuteri, A1
Jensen, PE1
Aalkjaer, C2
Pérez, NG2
Alvarez, BV1
Camilión de Hurtado, MC2
Cingolani, HE2
Good, DW1
Caflisch, CR1
George, T1
Batlle, D2
Redon, J2
Gutterman, C1
LaPointe, M1
Saleh, A1
Sharma, A1
Rombola, G1
Ye, M1
Alsheikha, W1
Gomez, L1
Sharma, AM2
Cetto, C1
Schorr, U1
Spies, KP1
Distler, A2
Sudhir, K1
Yock, PG1
Connolly, AJ1
Raja, RM1
Lerner, L1
Morris, M1
Lijnen, P1
Orosz, DE1
Hopfer, U1
Górriz, JL1
Sancho, A1
Lopez-Martin, JM1
Alcoy, E1
Catalán, C1
Pallardó, LM1
Smolarczyk, R1
Wójcicka-Jagodzińska, J1
Romejko, E1
Czajkowski, K1
Piekarski, P1
Teliga-Czajkowska, J1
Kuczyńska-Sicińska, J1
Cicco, G1
van der Kleij, AJ1
Passavanti, G1
Baldassare, G1
Manicone, A1
Vicenti, P1
Marra, M1
Izzo, P1
Coratelli, P1
Pirelli, A1
Sebastian, A2
Forman, A2
Mazouz, H1
Kacso, I1
Ghazali, A1
El Esper, N1
Moriniere, P1
Makdassi, R1
Hardy, P1
Westeel, PF1
Achard, JM1
Pruna, A1
Fournier, A1
Frassetto, L1
Halperin, ML1
Kamel, KS1
Ushikubi, F1
Sugimoto, Y1
Ichikawa, A1
Narumiya, S1
Chipperfield, AR1
Harper, AA1
Olson, JL1
Khanna, A1
Kurtzman, NA1
Cruz, DN1
Simon, DB1
Nelson-Williams, C1
Farhi, A1
Finberg, K1
Burleson, L1
Gill, JR1
Lifton, RP1
Landmann-Suter, R1
Struyvenberg, A1
Fadel, HE1
Northrop, G1
Misenhimer, HR1
Harp, RJ1
Wilkinson, PR1
Issler, H1
Hesp, R1
Raftery, EB1
Bravo, EL1
Tarazi, RC1
Dustan, HP1
Lewis, JW1
Messerli, FH1
Frohlich, ED1
Duke, M1
Hoffbrand, BI1
Edmonds, CJ1
Smith, T1
Valmin, K1
Hansen, T1
Bernardi, P1
Descovich, GC1
Rondina, M1
Pecoraro, F1
Lenzi, S1
Shul'tsev, GP2
Tsalenchuk, IaP2
Gilunova, NI1
Lowder, SC1
Brown, RD1
Carballo, AS1
Carney, S1
Morgan, T1
Wilson, M1
Matthews, G1
Roberts, R1
Cope, CL1
Loizou, S1
Izzard, AS1
Cragoe, EJ1
Heagerty, AM1
Syme, PD1
Aronson, JK1
Thompson, CH1
Williams, EM1
Green, Y1
Radda, GK1
Semplicini, A1
Ceolotto, G1
Marzola, M1
Inagaki, Y1
Amano, I1
Overlack, A1
Conrad, H1
Stumpe, KO1
Karniski, LP1
Luft, FC1
Zemel, MB1
Sowers, JA1
Fineberg, NS1
Weinberger, MH1
Soppi, E1
Viikari, J1
Seppälä, P1
Lehtonen, A1
Saarinen, R1
Miilunpalo, S1
Huidobro, F1
Videla, C1
Hernández, G1
Torres, H1
Jimenez, R1
Pérez, H1
Díaz, RA1
Johnson, BE1
Mehmel, HC1
Gordon, RD2
Zicha, J1
Kunes, J1
Jelínek, J1
Leont'eva, GR1
Govyrin, VA1
Withington, PS1
Durcan, JJ1
Weir, I1
Innis, R1
Savage, T1
Teschner, M1
Bahner, U1
Schaefer, RM1
Möslein, J1
Heidland, A1
Lucas, PA3
Lacour, B3
Comte, L2
McCarron, DA2
Drüeke, T3
Gierada, DS1
Bohr, DF1
Funder, J1
Sundar, S1
Sachdev, KK1
Vaish, SK1
Bhattacharya, SK1
Singh, VP1
Agarwal, SK1
Patton, RD1
Berkowitz, R1
Buchwald, RP1
Stein, E1
Pannier, JL1
Leusen, I1
Materson, BJ1
Oster, JR1
Perez-Stable, EC1
Maxwell, MH1
Miyazawa, T1
Zakharchenko, VN1
Dobrova, AS1
Kunau, RT1
Webb, HL1
Borman, SC1
Vohra, J1
Burrows, GD1
Logan, DA1
Howie, HB1
Crawford, J1
Kalinovskaia, IIa1
Kremer, D1
Brown, JJ2
Lever, AF2
Davies, DL1
Robertson, JI2
McConnell, SD1
Henkin, RI1
Fodor, JG1
Pfeiffer, CJ1
Papezik, VS1
Brunner, HR1
Sealey, JE1
Laragh, JH1
Degnbol, B1
Dorph, S1
Marner, T1
Lieberman, E1
Bergström, J1
Hultman, E1
Solheim, SB1
Gundersen, HJ1
Vohra, JK1
Aitchison, J1
Ferriss, JB1
Kay, AW1
Neville, AM1
Symington, T1
Hagge, W1
Winegrad, AI1
Clements, RS1
Fish, SA1
Morrison, JC1
Bucovaz, ET1
Wiser, WL1
Whybrew, WD1
King, JF1
Easton, R1
Dunn, M1
Paulson, OB1
Olesen, J1
Christensen, MS1
Morton, WE1
Salako, LA1
Geddes, RA1
Pawsey, CG1
O'Halloran, MW1
Blair-West, JR1
Coghlan, JP1
Denton, DA1
Funder, JW1
Nelson, J1
Scoggins, BA1
Wright, RD1
Ackerman, GL1
Paterson, JW1
Dollery, CT1
Haslam, RM1
Gordon, E1
Rossanda, M1
Takekoshi, N1
Retan, JW1
Dillon, HC1
Quellhorst, E1
Scheler, F1
Arnold, JE1
Healy, JK1
Hausmann, W1
Tárnoky, AL1

Clinical Trials (12)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Systolic Blood Pressure Intervention Trial[NCT01206062]9,361 participants (Actual)Interventional2010-10-31Completed
Development of a Mathematical Model for the Evaluation of the Potassium Kinetic During and After Hemodialysis for the Potassium Profiling in the Dialysate to Prevent Arrhythmias[NCT04563091]6 participants (Anticipated)Interventional2018-11-15Recruiting
Sleepiness and Tiredness Among Doctors Working In A Tertiary Hospital: Is it Work Related or Is There Underlying Sleep Disorders[NCT04020991]203 participants (Actual)Observational2018-10-01Completed
Efficiency of Speech Therapy in Resistant Hypertensive Patients With Mild Obstructive Sleep Apnea Syndrome[NCT03753633]50 participants (Anticipated)Interventional2017-10-01Active, not recruiting
Investigating the Effects of Wearing Compression Stockings to Improve Asthma Symptoms at Night[NCT03303586]40 participants (Anticipated)Interventional2017-02-21Recruiting
Piloting an Adaption of Cognitive Behavioral Therapy for Insomnia for Shift Workers (CBTI-Shift)[NCT05965609]60 participants (Anticipated)Interventional2023-12-08Recruiting
Impact of Dexmedetomidine Supplemented Analgesia on Sleep Quality in Patients at High-risk of Obstructive Sleep Apnea After Major Surgery: A Randomized, Double-blind, and Placebo-controlled Pilot Study[NCT04608331]Phase 4152 participants (Actual)Interventional2021-01-29Completed
Value of Liquid Potassium Magnesium Citrate in Controlling Hypertension[NCT02653560]Phase 430 participants (Actual)Interventional2012-09-30Completed
Randomized Trial of Sodium Bicarbonate in Renal Transplant Recipients With Low-normal Serum Bicarbonate Levels[NCT01225796]Early Phase 129 participants (Actual)Interventional2010-11-30Completed
Alkaline Diet for Insulin Sensitivity[NCT02501343]32 participants (Actual)Interventional2015-03-31Completed
Haemodynamic Consequences of Changing Potassium Concentrations in Haemodialysis Fluids[NCT01224314]24 participants (Actual)Interventional2007-09-30Completed
Clinical Significance of Heterozygosity for Mutations of the SLC12A3 Gene Coding for the Thiazide Sensitive Na-Cl Cotransporter[NCT02035046]250 participants (Anticipated)Interventional2013-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of CKD Participants Who Experienced a 50% Decline From Baseline eGFR

(NCT01206062)
Timeframe: 6 years

InterventionParticipants (Count of Participants)
Intensive Control of SBP10
Standard Control of SBP12

Number of Participants With All-cause Mortality

(NCT01206062)
Timeframe: 6 years

InterventionParticipants (Count of Participants)
Intensive Control of SBP155
Standard Control of SBP210

Number of Participants With First Occurrence of a Myocardial Infarction (MI), Acute Coronary Syndrome (ACS), Stroke, Heart Failure (HF), or CVD Death

(NCT01206062)
Timeframe: 6 years

InterventionParticipants (Count of Participants)
Intensive Control of SBP243
Standard Control of SBP319

Number of Patients With All-cause Dementia

A 3-step process was used ascertain incident cases of all-cause dementia. First, to identify possible cases of dementia a brief Cognition Screening Battery was administered to all participants. Participants who score below the pre-designated screening cut-point for possible cognitive impairment during follow-up were administered a more comprehensive and detailed neurocognitive test battery (the Extended Cognitive Assessment Battery) plus the Functional Assessment Questionnaire (FAQ) which assesses impairments in daily living skills as a result of cognitive impairments. Last, all the above available tests and questionnaire data were submitted to a centralized, web-based system for adjudication by a panel of dementia experts who assigned final study classifications of probable dementia (PD), mild cognitive impairment (MCI) or no impairment (NI). (NCT01206062)
Timeframe: 6 years

InterventionParticipants (Count of Participants)
Intensive Control of SBP149
Standard Control of SBP176

Participants Who Developed End Stage Renal Disease

(NCT01206062)
Timeframe: 6 years

InterventionParticipants (Count of Participants)
Intensive Control of SBP12
Standard Control of SBP8

Small Vessel Cerebral Ischemic Disease

"Change over 4 years in total white matter lesion volume from baseline Change over 4 years in total brain volume from baseline~Because of the skewed distribution for WML volume, we first applied an inverse hyperbolic sine transformation (asinh), which is similar to a log transformation but can accommodate values of zero. Linear mixed models, including random effects for participant and MRI facility, were used to estimate the change in WML volume and TBV between the treatment groups, including time since randomization (in days) and intracranial volume as covariates. Because the inverse hyperbolic sine transformation is nonlinear, and given the context of a mixed-effects model, back-transformation to the original scale of cm3 is difficult" (NCT01206062)
Timeframe: 4 years

,
Interventionasinh(cm3) (Mean)
Change in total white matter lesion volume from baChange in total brain volume from baseline
Intensive Control of SBP0.23-7.7
Standard Control of SBP0.37-6.8

24-hour Average Systolic Blood Pressure

Systolic blood pressure was measured through an ambulatory blood pressure monitoring device worn by each participant for 24 hours after completing each treatment phase. This devise measures blood pressure intermittently throughout the day and night and provides the average of all readings. (NCT02653560)
Timeframe: 4 weeks

InterventionmmHg (Mean)
Potassium Magnesium Citrate (KMgCit) Arm127
Potassium Citrate Arm127
Potassium Chloride Arm126
Placebo129

Reviews

20 reviews available for hydrogen carbonate and Blood Pressure, High

ArticleYear
Dialysate and serum potassium in hemodialysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2015, Volume: 66, Issue:1

    Topics: Aged; Arrhythmias, Cardiac; Azithromycin; Bicarbonates; Black or African American; Calcium; Coronary

2015
Established and Emerging Strategies in the Treatment of Chronic Kidney Disease.
    Seminars in nephrology, 2016, Volume: 36, Issue:4

    Topics: Allopurinol; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bicarbonate

2016
Knockout mouse models for intestinal electrolyte transporters and regulatory PDZ adaptors: new insights into cystic fibrosis, secretory diarrhoea and fructose-induced hypertension.
    Experimental physiology, 2009, Volume: 94, Issue:2

    Topics: Animals; Bicarbonates; Biological Transport; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conducta

2009
Diet-induced metabolic acidosis.
    Clinical nutrition (Edinburgh, Scotland), 2011, Volume: 30, Issue:4

    Topics: Acid-Base Equilibrium; Acidosis; Bicarbonates; Biomarkers; Cardiovascular Diseases; Citric Acid; Die

2011
Volume control in peritoneal dialysis patients: role of new dialysis solutions.
    Blood purification, 2004, Volume: 22, Issue:1

    Topics: Acidosis; Bicarbonates; Blood Volume; Double-Blind Method; Glucans; Glucose; Glycation End Products,

2004
Pathophysiology of the syndrome of hyporeninemic hypoaldosteronism.
    Metabolism: clinical and experimental, 1980, Volume: 29, Issue:2

    Topics: Acidosis; Aged; Aldosterone; Ammonia; Angiotensin II; Bicarbonates; Cations, Monovalent; Extracellul

1980
Acid-base status and intracellular pH regulation in lymphocytes from rats with genetic hypertension.
    Journal of the American Society of Nephrology : JASN, 1994, Volume: 5, Issue:5 Suppl 1

    Topics: Acid-Base Equilibrium; Animals; Bicarbonates; Carbon Dioxide; Chlorides; Hydrogen-Ion Concentration;

1994
Alterations in sodium metabolism as an etiological model for hypertension.
    Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:3

    Topics: Antiporters; Bicarbonates; Blood Pressure; Calcium; Chlorides; Erythrocytes; Humans; Hypertension; I

1995
Differing effects of supplemental KCl and KHCO3: pathophysiological and clinical implications.
    Seminars in nephrology, 1999, Volume: 19, Issue:5

    Topics: Adult; Animals; Bicarbonates; Child; Child, Preschool; Dietary Supplements; Humans; Hypertension; Mi

1999
Dynamic interactions between integrative physiology and molecular medicine: the key to understand the mechanism of action of aldosterone in the kidney.
    Canadian journal of physiology and pharmacology, 2000, Volume: 78, Issue:8

    Topics: Acid-Base Equilibrium; Aldosterone; Animals; Bicarbonates; Humans; Hypertension; Kidney; Sodium Chlo

2000
Roles of prostanoids revealed from studies using mice lacking specific prostanoid receptors.
    Japanese journal of pharmacology, 2000, Volume: 83, Issue:4

    Topics: Animals; Asthma; Bicarbonates; Colonic Neoplasms; Dinoprost; Dinoprostone; Female; Fever; Hypertensi

2000
Chloride in smooth muscle.
    Progress in biophysics and molecular biology, 2000, Volume: 74, Issue:3-5

    Topics: Animals; Bicarbonates; Biophysical Phenomena; Biophysics; Carrier Proteins; Chlorides; Energy Metabo

2000
Metabolic alkalosis.
    Respiratory care, 2001, Volume: 46, Issue:4

    Topics: Alkalosis; Bicarbonates; Chlorides; Diuretics; Glomerular Filtration Rate; Humans; Hydrochloric Acid

2001
High blood pressure. A side effect of drugs, poisons, and food.
    Archives of internal medicine, 1979, Volume: 139, Issue:6

    Topics: Androgens; Anesthetics; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Antihypertensive

1979
Current drug therapy - thiazide diuretics.
    American journal of hospital pharmacy, 1975, Volume: 32, Issue:5

    Topics: Antihypertensive Agents; Benzothiadiazines; Bicarbonates; Chemical Phenomena; Chemistry; Chlorides;

1975
[Erythrocyte Na+/H+ exchange and arterial hypertension].
    Giornale italiano di cardiologia, 1991, Volume: 21, Issue:12

    Topics: Bicarbonates; Biochemical Phenomena; Biochemistry; Electrochemistry; Erythrocytes; Humans; Hydrogen;

1991
Regulation of intracellular pH and its role in vascular smooth muscle function.
    Journal of hypertension, 1990, Volume: 8, Issue:3

    Topics: Animals; Bicarbonates; Calcium; Cell Division; Cricetinae; Guinea Pigs; Hydrogen-Ion Concentration;

1990
Syndrome of hypertension and hyperkalemia with normal glomerular filtration rate.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Bicarbonates; Blood Pressure; Child; Diet, Sodium-Restricted; Diuret

1986
[Vertigo].
    Klinicheskaia meditsina, 1974, Volume: 52, Issue:9

    Topics: Acute Disease; Age Factors; Aortic Valve Insufficiency; Arteriosclerosis; Atropine; Atropine Derivat

1974
Diabetic ketoacidosis.
    The Medical clinics of North America, 1971, Volume: 55, Issue:4

    Topics: Acute Kidney Injury; Bicarbonates; Brain Edema; Diabetic Ketoacidosis; Humans; Hypertension; Insulin

1971

Trials

17 trials available for hydrogen carbonate and Blood Pressure, High

ArticleYear
Serum bicarbonate and cardiovascular events in hypertensive adults: results from the Systolic Blood Pressure Intervention Trial.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2020, 08-01, Volume: 35, Issue:8

    Topics: Aged; Bicarbonates; Biomarkers; Cardiovascular Diseases; Female; Humans; Hypertension; Incidence; Ma

2020
Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy.
    Journal of the American Society of Nephrology : JASN, 2009, Volume: 20, Issue:12

    Topics: Adult; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitor

2009
Effects of potassium chloride and potassium bicarbonate on endothelial function, cardiovascular risk factors, and bone turnover in mild hypertensives.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:3

    Topics: Adult; Albuminuria; Bicarbonates; Blood Pressure; Bone Remodeling; Brachial Artery; Calcium; Cross-O

2010
Higher serum bicarbonate levels within the normal range are associated with better survival and renal outcomes in African Americans.
    Kidney international, 2011, Volume: 79, Issue:3

    Topics: Adult; Aged; Antihypertensive Agents; Bicarbonates; Biomarkers; Black or African American; Chronic D

2011
Estimated net endogenous acid production and serum bicarbonate in African Americans with chronic kidney disease.
    Clinical journal of the American Society of Nephrology : CJASN, 2011, Volume: 6, Issue:7

    Topics: Acidosis; Adult; Aged; Bicarbonates; Black or African American; Chi-Square Distribution; Chronic Dis

2011
Response of thiazide-induced hypokalemia to amiloride.
    JAMA, 1983, Jan-14, Volume: 249, Issue:2

    Topics: Aldosterone; Amiloride; Bicarbonates; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypert

1983
Renal acid-base excretion in normotensive salt-sensitive humans.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:6

    Topics: Acid-Base Equilibrium; Adult; Ammonium Chloride; Analysis of Variance; Bicarbonates; Blood Pressure;

1993
[Evaluation of fetal condition in pregnancy complicated by hypertension--biochemical assessment of amniotic fluid. III. Acid-base balance].
    Ginekologia polska, 1996, Volume: 67, Issue:12

    Topics: Acid-Base Equilibrium; Adult; Amniotic Fluid; Bicarbonates; Carbon Dioxide; Female; Humans; Hydrogen

1996
Spironolactone in essential hypertension: evidence against its effect through mineralocorticoid antagonism.
    British medical journal, 1976, Mar-20, Volume: 1, Issue:6011

    Topics: Adult; Bicarbonates; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertension; Male; M

1976
Treatment of benign essential hypertension: comparison of furosemide and hydrochlorothiazide.
    European journal of clinical pharmacology, 1975, Aug-14, Volume: 8, Issue:6

    Topics: Adult; Bicarbonates; Blood Pressure; Body Weight; Clinical Trials as Topic; Diuresis; Dose-Response

1975
The influence of oral potassium citrate/bicarbonate on blood pressure in essential hypertension during unrestricted salt intake.
    Klinische Wochenschrift, 1991, Volume: 69 Suppl 25

    Topics: Adult; Aldosterone; Bicarbonates; Blood Pressure; Citrates; Female; Humans; Hypertension; Male; Midd

1991
Sodium bicarbonate and sodium chloride: effects on blood pressure and electrolyte homeostasis in normal and hypertensive man.
    Journal of hypertension, 1990, Volume: 8, Issue:7

    Topics: Adult; Bicarbonates; Blood Pressure; Female; Humans; Hypertension; Male; Mineral Waters; Randomized

1990
Haemodynamic and metabolic effects of prophylactic nitroglycerin infusion in the immediate period following coronary artery bypass grafting.
    European heart journal, 1988, Volume: 9 Suppl A

    Topics: Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Coronary Artery Bypass; Female; Hemodynamics

1988
Potassium supplementation in essential hypertension--a double blind placebo controlled study.
    The Journal of the Association of Physicians of India, 1985, Volume: 33, Issue:12

    Topics: Bicarbonates; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Humans; Hypertension

1985
Antihypertensive effects of metolazone (zaroxolyn).
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:9

    Topics: Adult; Aged; Antihypertensive Agents; Bicarbonates; Blood Glucose; Blood Pressure; Blood Urea Nitrog

1974
The effect of different diuretics on elevated blood pressure and serum potassium.
    Acta medica Scandinavica, 1973, Volume: 193, Issue:5

    Topics: Adult; Aged; Amides; Bicarbonates; Blood Pressure; Chlorides; Clopamide; Creatinine; Depression, Che

1973
Amiloride hydrochloride in hypertensive patients.
    British medical journal, 1968, Feb-17, Volume: 1, Issue:5589

    Topics: Bicarbonates; Blood Pressure; Chlorides; Depression, Chemical; Diuretics; Drug Synergism; Guanidines

1968

Other Studies

111 other studies available for hydrogen carbonate and Blood Pressure, High

ArticleYear
miRNA-23a modulates sodium-hydrogen exchanger 1 expression: studies in medullary thick ascending limb of salt-induced hypertensive rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2023, 02-28, Volume: 38, Issue:3

    Topics: Animals; Bicarbonates; Essential Hypertension; Humans; Hypertension; Kidney Medulla; MicroRNAs; Rats

2023
Demographic and clinical profile of black patients with chronic kidney disease attending a tertiary hospital in Johannesburg, South Africa.
    PloS one, 2022, Volume: 17, Issue:9

    Topics: Acidosis; Aged; Allopurinol; Anemia; Bicarbonates; Cross-Sectional Studies; Diabetes Mellitus; Doxaz

2022
Serum bicarbonate as a cardiovascular risk factor: evolving from 'non-traditional'?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2020, 08-01, Volume: 35, Issue:8

    Topics: Adult; Bicarbonates; Blood Pressure; Cardiovascular Diseases; Humans; Hypertension; Risk Factors

2020
Independent associations between arterial bicarbonate, apnea severity and hypertension in obstructive sleep apnea.
    Respiratory research, 2017, 06-28, Volume: 18, Issue:1

    Topics: Adult; Bicarbonates; Blood Gas Analysis; Cohort Studies; Female; Humans; Hypertension; Male; Middle

2017
Identification of SLC26A transporters involved in the Cl⁻/HCO₃⁻ exchange in proximal tubular cells from WKY and SHR.
    Life sciences, 2013, Oct-06, Volume: 93, Issue:12-14

    Topics: Animals; Antiporters; Bicarbonates; Biological Transport; Cells, Cultured; Chloride-Bicarbonate Anti

2013
Plasma bicarbonate and odds of incident hypertension.
    American journal of hypertension, 2013, Volume: 26, Issue:12

    Topics: Adult; Bicarbonates; Biomarkers; Boston; Buffers; Case-Control Studies; Female; Follow-Up Studies; H

2013
Reduced sarcolemmal expression and function of the NBCe1 isoform of the Na⁺-HCO₃⁻ cotransporter in hypertrophied cardiomyocytes of spontaneously hypertensive rats: role of the renin-angiotensin system.
    Cardiovascular research, 2014, Feb-01, Volume: 101, Issue:2

    Topics: Ammonium Compounds; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensi

2014
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
STOP-Bang Questionnaire: A Practical Approach to Screen for Obstructive Sleep Apnea.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Age Factors; Bicarbonates; Body Mass Index; Comorbidity; Fatigue; Humans; Hypertension; Mass Screeni

2016
Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Acidosis; Animals; Bicarbonates; Biomarkers; Creatinine; DNA (Cytosine-5-)-Methyltransferase 1; DNA

2016
Serum Bicarbonate Is Associated with Heart Failure in the Multi-Ethnic Study of Atherosclerosis.
    American journal of nephrology, 2017, Volume: 45, Issue:2

    Topics: Aged; Antihypertensive Agents; Atherosclerosis; Bicarbonates; Blood Pressure; Creatinine; Diuretics;

2017
Posttranslational mechanisms associated with reduced NHE3 activity in adult vs. young prehypertensive SHR.
    American journal of physiology. Renal physiology, 2010, Volume: 299, Issue:4

    Topics: Absorption; Aging; Animals; Bicarbonates; Blood Pressure; Dipeptidyl Peptidase 4; Disease Models, An

2010
High prevalence of liddle syndrome phenotype among hypertensive US Veterans in Northwest Louisiana.
    Journal of clinical hypertension (Greenwich, Conn.), 2010, Volume: 12, Issue:11

    Topics: Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Bicarbonates; Blood Pressure; Cross-S

2010
In vivo alterations in cardiac metabolism and function in the spontaneously hypertensive rat heart.
    Cardiovascular research, 2012, Jul-01, Volume: 95, Issue:1

    Topics: Adenosine Triphosphate; Animals; Bicarbonates; Carbon Dioxide; Cardiomegaly; Citric Acid Cycle; Hydr

2012
Risk factors for hospital death of patients with end-stage renal disease without previous diagnosis of severe chronic renal failure arriving in an emergency situation at the hospital.
    Renal failure, 2003, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Bicarbonates; Biomarkers; Brazil; Child; Cr

2003
[TREATMENT OF URIC LITHIASIS].
    Rein et foie, maladies de la nutrition; actualites, 1963, Volume: 6

    Topics: Bicarbonates; Calcium Metabolism Disorders; Citrates; Diet; Diet Therapy; Diuresis; Gout; Humans; Hy

1963
FURTHER OBSERVATIONS ON THE RENAL PRODUCTION OF ACID IN UREMIA.
    Metabolism: clinical and experimental, 1964, Volume: 13

    Topics: Acids; Ammonium Compounds; Bicarbonates; Blood Chemical Analysis; Carbon Dioxide; Chlorides; Creatin

1964
POLYTHIAZIDE IN THE MANAGEMENT OF HYPERTENSIVE DISEASE. I. EFFECTS OF WATER AND ELECTROLYTE METABOLISM.
    Current therapeutic research, clinical and experimental, 1964, Volume: 6

    Topics: Benzothiadiazines; Bicarbonates; Biomedical Research; Blood Chemical Analysis; Blood Pressure; Blood

1964
[TRICHLORMETHIAZIDE (FLUITRAN) AS A DIURETIC].
    Ugeskrift for laeger, 1964, Mar-05, Volume: 126

    Topics: Bicarbonates; Blood Chemical Analysis; Chlorides; Chlorothiazide; Creatine; Creatinine; Diuretics; E

1964
[TRICHLORMETHIAZIDE (FLUITRAN) AS A HYPOTENSIVE AGENT].
    Ugeskrift for laeger, 1964, Mar-05, Volume: 126

    Topics: Antihypertensive Agents; Bicarbonates; Blood Chemical Analysis; Blood Pressure Determination; Chlori

1964
TREATMENT OF CHRONIC RENAL FAILURE.
    Modern treatment, 1964, Volume: 1

    Topics: Acidosis; Anemia; Anti-Bacterial Agents; Bicarbonates; Chloramphenicol; Classification; Diet; Diet T

1964
A COMPARATIVE STUDY OF THE DIURETICS CHLORTHALIDONUM AND CYCLOPENTHIAZIDUM.
    Acta medica Scandinavica, 1964, Volume: 175

    Topics: Benzothiadiazines; Bicarbonates; Biomedical Research; Blood; Chlorides; Chlorthalidone; Diet, Sodium

1964
EFFECTS OF ACIDOSIS ON RESPIRATORY FUNCTION.
    Annals of the New York Academy of Sciences, 1965, Mar-24, Volume: 121

    Topics: Acidosis; Bicarbonates; Carbon Dioxide; Hemoglobins; Hydrochloric Acid; Hypertension; Hypertension,

1965
METABOLIC ALTERATIONS NOTED IN CYANOTIC AND ACYANOTIC INFANTS DURING OPERATION UNDER HYPERBARIC CONDITIONS.
    The Journal of thoracic and cardiovascular surgery, 1965, Volume: 50

    Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Aortic Coarctation; Aortic Valve Stenosis; A

1965
Effects of adrenalectomy, desoxycorticosterone acetate and increased fluid intake on intake of sodium chloride and bicarbonate by hypertensive and normal rats.
    The American journal of physiology, 1951, Volume: 164, Issue:2

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Animals; Bicarbonates; Blood Pressure; Blood Pressure Determ

1951
[Clinical experiences with TEAB (tetraethylammonium bromide SPOFA)].
    Casopis lekaru ceskych, 1951, Jun-29, Volume: 90, Issue:26

    Topics: Bicarbonates; Blood Pressure; Blood Vessels; Hypertension; Tetraethylammonium

1951
Impaired 11-beta hydroxysteroid dehydrogenase type 2 activity in sweat gland ducts in human essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:4

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenal Cortex Hormones; Adult; Aldosterone; Bicarbonat

2004
Chloride-dominant salt sensitivity in the stroke-prone spontaneously hypertensive rat.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:5

    Topics: Animals; Bicarbonates; Blood Pressure; Body Weight; Chlorides; Creatinine; Drug Combinations; Electr

2005
Donor characteristics associated with liver graft survival.
    Transplantation, 2005, May-27, Volume: 79, Issue:10

    Topics: Acidosis; Adolescent; Adult; Aged; Aging; Bicarbonates; Female; Graft Survival; Humans; Hypertension

2005
The renal physiology of pendrin (SLC26A4) and its role in hypertension.
    Novartis Foundation symposium, 2006, Volume: 273

    Topics: Absorption; Acid-Base Equilibrium; Aldosterone; Animals; Anion Transport Proteins; Bicarbonates; Blo

2006
Dietary chloride and bicarbonate as determinants of desoxycorticosterone hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:3

    Topics: Animals; Bicarbonates; Blood Pressure; Desoxycorticosterone; Diet; Drug Interactions; Hypertension;

1984
Beta blocker therapy in 125 cases of hypertension during pregnancy.
    Clinical and experimental hypertension. Part B, Hypertension in pregnancy, 1983, Volume: 2, Issue:1

    Topics: Abnormalities, Drug-Induced; Adrenergic beta-Antagonists; Adult; Apgar Score; Bicarbonates; Birth We

1983
Effect of chloride on renin and blood pressure responses to sodium chloride.
    Annals of internal medicine, 1983, Volume: 98, Issue:5 Pt 2

    Topics: Adult; Animals; Bicarbonates; Blood Pressure; Chlorides; Diet; Dogs; Humans; Hypertension; Male; Nit

1983
[Metabolism of potassium and sodium when administered with different anions to patients with ischemic heart disease and arterial hypertension].
    Meditsinskaia radiologiia, 1984, Volume: 29, Issue:3

    Topics: Bicarbonates; Coronary Disease; Humans; Hypertension; Injections, Intravenous; Potassium; Potassium

1984
Salt-sensitive hypertension: contribution of chloride.
    Science (New York, N.Y.), 1984, Mar-30, Volume: 223, Issue:4643

    Topics: Animals; Bicarbonates; Blood Pressure; Chlorides; Diet; Hypertension; Kidney; Loop of Henle; Male; P

1984
[Prevention of arterial hypertension sailors].
    Vrachebnoe delo, 1981, Issue:2

    Topics: Bicarbonates; Humans; Hypertension; Natriuresis; Naval Medicine; Sodium Chloride; USSR

1981
Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:4

    Topics: Adult; Aldosterone; Amiloride; Angiotensin II; Bendroflumethiazide; Bicarbonates; Blood Pressure; Di

1980
Hypokalemia during the treatment of arterial hypertension with diuretics.
    Canadian Medical Association journal, 1980, Apr-19, Volume: 122, Issue:8

    Topics: Adult; Aged; Bicarbonates; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertens

1980
The regulation of pH in resistance arteries from spontaneously hypertensive and Wistar-Kyoto rats: the effect of bicarbonate.
    Journal of hypertension, 1995, Volume: 13, Issue:5

    Topics: Animals; Arteries; Bicarbonates; Hydrogen-Ion Concentration; Hypertension; Male; Rats; Rats, Inbred

1995
pHi regulation in myocardium of the spontaneously hypertensive rat. Compensated enhanced activity of the Na(+)-H+ exchanger.
    Circulation research, 1995, Volume: 77, Issue:6

    Topics: Animals; Bicarbonates; Buffers; Chlorides; Data Interpretation, Statistical; Fluorescence; Hydrogen-

1995
Prostaglandin E2 regulation of ion transport is absent in medullary thick ascending limbs from SHR.
    The American journal of physiology, 1995, Volume: 269, Issue:1 Pt 2

    Topics: Absorption; Animals; Arginine Vasopressin; Bicarbonates; Biological Transport; Chlorides; Cholera To

1995
Regulation of intracellular pH in the spontaneously hypertensive rat. Role of bicarbonate-dependent transporters.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:4

    Topics: Animals; Antiporters; Bicarbonates; Buffers; Carbon Dioxide; Cells, Cultured; Chloride-Bicarbonate A

1994
Potassium preserves endothelial function and enhances aortic compliance in Dahl rats.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:3

    Topics: Acetylcholine; Animals; Bicarbonates; Blood Pressure; Compliance; Hypertension; Male; Nitric Oxide;

1993
Hypertension with combined pancreas-kidney transplants in patients with diabetic nephropathy.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 2

    Topics: Bicarbonates; Blood Glucose; Blood Pressure; Creatinine; Diabetes Mellitus, Type 1; Diabetic Nephrop

1993
Pathophysiological consequences of changes in the coupling ratio of Na,K-ATPase for renal sodium reabsorption and its implications for hypertension.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:2

    Topics: Animals; Bicarbonates; Carrier Proteins; Humans; Hypertension; Kidney; Kidney Tubules, Proximal; Kin

1996
Rhabdomyolysis and acute renal failure associated with gemfibrozil therapy.
    Nephron, 1996, Volume: 74, Issue:2

    Topics: Acute Kidney Injury; Aged; Angiotensin-Converting Enzyme Inhibitors; Bicarbonates; Diabetes Mellitus

1996
Effect of bicarbonate haemodialysis on peripheral oxygen availability in mild hypertensive patients.
    Advances in experimental medicine and biology, 1997, Volume: 428

    Topics: 2,3-Diphosphoglycerate; Arterial Occlusive Diseases; Bicarbonates; Female; Glucosephosphate Dehydrog

1997
Normotensive salt sensitivity: effects of race and dietary potassium.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:1

    Topics: Adult; Aged; Bicarbonates; Black People; Blood Pressure; Data Interpretation, Statistical; Humans; H

1999
Risk factors of renal failure progression two years prior to dialysis.
    Clinical nephrology, 1999, Volume: 51, Issue:6

    Topics: Anemia; Bicarbonates; Blood Proteins; Calcium; Cholesterol; Creatinine; Diabetic Nephropathies; Dise

1999
[What is Na+/H+ exchanger guilty of in cardiology?].
    Medicina, 2000, Volume: 60, Issue:5 Pt 2

    Topics: Acidosis; Angiotensin II; Animals; Bicarbonates; Calcium; Carbon Dioxide; Cell Membrane Permeability

2000
Chloride-sensitive renal microangiopathy in the stroke-prone spontaneously hypertensive rat.
    Kidney international, 2001, Volume: 59, Issue:3

    Topics: Animals; Bicarbonates; Blood Pressure; Chlorides; Creatinine; Disease Susceptibility; Hypertension;

2001
Mutations in the Na-Cl cotransporter reduce blood pressure in humans.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:6

    Topics: Alkalosis; Bicarbonates; Blood Pressure; Calcium; Carrier Proteins; Founder Effect; Genotype; Hetero

2001
Initial potassium loss and hypokalaemia during chlorthalidone administration in patients with essential hypertension: the influence of dietary sodium restriction.
    European journal of clinical investigation, 1978, Volume: 8, Issue:3

    Topics: Adult; Bicarbonates; Chlorides; Chlorthalidone; Diet, Sodium-Restricted; Female; Humans; Hydrogen-Io

1978
Acid base balance in pre-eclamptic, hypertensive and diabetic pregnancies. Maternal blood and amniotic fluid studies.
    Journal of perinatal medicine, 1979, Volume: 7, Issue:4

    Topics: Acid-Base Equilibrium; Adult; Amniotic Fluid; Bicarbonates; Carbon Dioxide; Female; Humans; Hydrogen

1979
Total body and serum potassium during prolonged thiazide therapy for essential hypertension.
    Lancet (London, England), 1975, Apr-05, Volume: 1, Issue:7910

    Topics: Bendroflumethiazide; Bicarbonates; Blood Pressure; Blood Pressure Determination; Humans; Hypertensio

1975
Dissociation between renin and arterial pressure responses to beta-adrenergic blockade in human essential hypertension.
    Circulation research, 1975, Volume: 36, Issue:6 Suppl 1

    Topics: Adrenergic beta-Antagonists; Bicarbonates; Blood Pressure; Chlorides; Creatinine; Diuretics; Drug Ad

1975
Thiazide-induced hypokalemia. Association with acute myocardial infarction and ventricular fibrillation.
    JAMA, 1978, Jan-02, Volume: 239, Issue:1

    Topics: Acute Disease; Aged; Benzothiadiazines; Bicarbonates; Diuretics; Female; Humans; Hypertension; Hypok

1978
[Renal control of acid-base equilibrium during dyslipidemia].
    Minerva medica, 1977, Feb-18, Volume: 68, Issue:8

    Topics: Acid-Base Equilibrium; Adolescent; Adult; Aged; Bicarbonates; Child; Female; Humans; Hyperlipidemias

1977
[Comparative evaluation of the saluretic effect of furosemide, sodium bicarbonate and heparin].
    Terapevticheskii arkhiv, 1976, Volume: 48, Issue:7

    Topics: Bicarbonates; Drug Evaluation; Furosemide; Glomerulonephritis; Heparin; Humans; Hypertension; Natriu

1976
Hypertension corrected by discontinuing chronic sodium bicarbonate ingestion. Subsequent transient hypoaldosteronism.
    The American journal of medicine, 1975, Volume: 58, Issue:2

    Topics: 17-Hydroxycorticosteroids; Aldosterone; Angiotensin II; Antihypertensive Agents; Bicarbonates; Calci

1975
Aborted malignant hyperthermia: case report.
    Canadian Anaesthetists' Society journal, 1975, Volume: 22, Issue:2

    Topics: Acidosis; Adult; Anesthesia, General; Aspartate Aminotransferases; Bicarbonates; Creatine Kinase; Fe

1975
Sodium restriction and thiazide diuretics in the treatment of hypertension.
    The Medical journal of Australia, 1975, Jun-28, Volume: 1, Issue:26

    Topics: Amiloride; Bicarbonates; Body Weight; Chlorothiazide; Diet, Sodium-Restricted; Diuretics; Humans; Hy

1975
Deoxycorticosterone excretion in normal, hypertensive and hypokalaemic subjects.
    Clinical science and molecular medicine, 1975, Volume: 48, Issue:2

    Topics: Aldosterone; Animals; Bicarbonates; Blood Pressure; Cross Reactions; Desoxycorticosterone; Humans; H

1975
Intracellular pH in human resistance arteries in essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:6 Pt 1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo

1991
Na+/H+ and HCO3-/Cl- exchange in the control of intracellular pH in vivo in the spontaneously hypertensive rat.
    Clinical science (London, England : 1979), 1991, Volume: 81, Issue:6

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo

1991
[Bicarbonate dialysate].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49 Suppl

    Topics: Acetates; Acetic Acid; Adult; Aged; Aged, 80 and over; Bicarbonates; Buffers; Calcium Carbonate; Che

1991
Abnormal acid-base regulation in salt-sensitive normotensive man.
    Klinische Wochenschrift, 1991, Volume: 69 Suppl 25

    Topics: Acid-Base Imbalance; Acidosis; Adult; Animals; Bicarbonates; Blood Pressure; Humans; Hydrogen-Ion Co

1991
Potential role of Cl-HCO3 exchange in regulating vascular tone.
    Hypertension (Dallas, Tex. : 1979), 1990, Volume: 15, Issue:1

    Topics: Animals; Bicarbonates; Biological Transport; Carbon Dioxide; Carrier Proteins; Chloride-Bicarbonate

1990
Unusual association of hyperkalemia and hypertension.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:2

    Topics: Adult; Aldosterone; Bicarbonates; Erythrocytes; Female; Humans; Hyperkalemia; Hypertension; Ion Chan

1986
[Lactic acidosis in diabetic patients associated with buformin].
    Revista medica de Chile, 1989, Volume: 117, Issue:1

    Topics: Acidosis, Lactic; Aged; Bicarbonates; Biguanides; Buformin; Diabetes Mellitus; Diabetic Angiopathies

1989
Resistant hypertension due to pica (baking soda)
    Lancet (London, England), 1989, Mar-11, Volume: 1, Issue:8637

    Topics: Adult; Anemia, Hypochromic; Bicarbonates; Female; Humans; Hypertension; Patient Compliance; Pica; So

1989
[Therapy of acute myocardial infarct].
    Deutsche medizinische Wochenschrift (1946), 1985, May-10, Volume: 110, Issue:19

    Topics: Acidosis; Analgesics; Atropine; Bicarbonates; Bradycardia; Cardiac Complexes, Premature; Critical Ca

1985
Dietary chloride as a determinant of disordered calcium metabolism in salt-dependent hypertension.
    Life sciences, 1985, Mar-11, Volume: 36, Issue:10

    Topics: Animals; Bicarbonates; Blood Pressure; Body Weight; Calcium; Desoxycorticosterone; Diet; Hypertensio

1985
The importance of sodium and chloride ions for the development of DOCA-NaCl hypertension: a haemodynamic study.
    Physiologia Bohemoslovaca, 1986, Volume: 35, Issue:4

    Topics: Animals; Bicarbonates; Chlorides; Desoxycorticosterone; Hemodynamics; Hypertension; Male; Rats; Rats

1986
Early functional effects of various antihypertensive drugs in chronically uremic rats.
    Kidney international. Supplement, 1988, Volume: 25

    Topics: Acidosis; Animals; Antihypertensive Agents; Bicarbonates; Chlorides; Chronic Disease; Creatinine; Hy

1988
Abnormal parameters of acid-base balance in genetic hypertension.
    Kidney international. Supplement, 1988, Volume: 25

    Topics: Acid-Base Equilibrium; Animals; Bicarbonates; Calcium; Hydrogen-Ion Concentration; Hypertension; Mal

1988
The influence of potassium and bicarbonate on red blood cell sodium in the DOCA-hypertensive pig.
    Clinical and experimental hypertension. Part A, Theory and practice, 1988, Volume: 10, Issue:2

    Topics: Animals; Bicarbonates; Desoxycorticosterone; Erythrocytes; Female; Hypertension; Potassium; Sodium;

1988
Pathogenesis of abnormal acid-base balance in the young spontaneously hypertensive rat.
    Clinical science (London, England : 1979), 1988, Volume: 75, Issue:1

    Topics: Acidosis; Animals; Bicarbonates; Calcium; Creatinine; Hydrogen-Ion Concentration; Hypertension; Male

1988
Membrane transport pathways and essential hypertension.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1986, Volume: 180

    Topics: Bicarbonates; Biological Transport, Active; Cell Membrane; Chlorides; Erythrocytes; Humans; Hyperten

1986
Disturbance of acid-base balance in the young spontaneously hypertensive rat.
    Clinical science (London, England : 1979), 1987, Volume: 73, Issue:2

    Topics: Acid-Base Imbalance; Anesthesia, General; Animals; Bicarbonates; Blood Pressure; Calcium; Hydralazin

1987
Hypothermia and profound acidosis due to benign prostatic hyperplasia.
    The Journal of urology, 1971, Volume: 105, Issue:4

    Topics: Acetazolamide; Acidosis; Aged; Bicarbonates; Glaucoma; Hot Temperature; Humans; Hypertension; Hypoth

1971
Proceedings: Influence of changes in the acid-base balance on cerebral blood flow after an actue hypertensive insult.
    Archives internationales de physiologie et de biochimie, 1974, Volume: 82, Issue:4

    Topics: Animals; Bicarbonates; Blood-Brain Barrier; Brain; Carbon Dioxide; Cats; Cerebrovascular Circulation

1974
[Sodium and arterial hypertension].
    La Presse medicale, 1969, Apr-23, Volume: 77, Issue:20

    Topics: Animals; Arteries; Bicarbonates; Biological Transport; Cardiac Output; Cell Membrane Permeability; C

1969
[Clinical pathophysiological study of venous blood gas partial pressures and pH of organs in various diseases (author's transl)].
    Japanese circulation journal, 1974, Volume: 38, Issue:5

    Topics: Adolescent; Adult; Bicarbonates; Brain; Carbon Dioxide; Cerebrovascular Circulation; Chronic Disease

1974
[Use of sodium hydrocarbonate in hypertensive disease and renal hypertension].
    Klinicheskaia meditsina, 1974, Volume: 52, Issue:10

    Topics: Adolescent; Antihypertensive Agents; Bicarbonates; Drug Therapy, Combination; Humans; Hydrocarbons;

1974
Characteristics of sodium reabsorption in the loop of Henle and distal tubule.
    The American journal of physiology, 1974, Volume: 227, Issue:5

    Topics: Animals; Aorta; Bicarbonates; Biological Transport; Blood Pressure; Blood Volume; Constriction; Extr

1974
Cardiovascular complications of tricyclic antidepressant overdosage.
    Drugs, 1974, Volume: 8, Issue:6

    Topics: Antidepressive Agents; Arrhythmias, Cardiac; Bicarbonates; Cardiovascular Diseases; Electrocardiogra

1974
Anaesthesia and renal transplantation: an analysis of fifty-six cases.
    British journal of anaesthesia, 1974, Volume: 46, Issue:1

    Topics: Adolescent; Adult; Anesthesia, General; Atropine; Bicarbonates; Chlorides; Female; Hematocrit; Hemog

1974
Amiloride in primary hyperaldosteronism with chronic peptic ulceration.
    British medical journal, 1973, Apr-28, Volume: 2, Issue:5860

    Topics: Aged; Amiloride; Bicarbonates; Blood Pressure; Body Water; Chlorides; Chronic Disease; Diuretics; Fe

1973
Increased preference for Na + and K + salts in spontaneously hypertensive (SH) rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 143, Issue:1

    Topics: Animals; Bicarbonates; Chlorides; Feeding Behavior; Hypertension; Male; Potassium; Rats; Rats, Inbre

1973
Relationship of drinking water quality (hardness-softness) to cardiovascular mortality in Newfoundland.
    Canadian Medical Association journal, 1973, Jun-02, Volume: 108, Issue:11

    Topics: Adult; Aged; Bicarbonates; Calcium; Cardiovascular Diseases; Chlorides; Female; Heart; Humans; Hyper

1973
Renin subgroups in essential hypertension. Further analysis of their pathophysiological and epidemiological characteristics.
    Circulation research, 1973, May-05, Volume: 32

    Topics: Administration, Oral; Adult; Age Factors; Aged; Aldosterone; Bicarbonates; Blood Urea Nitrogen; Diet

1973
Management of acute renal failure in infants and children.
    Nephron, 1973, Volume: 11, Issue:2

    Topics: Acidosis; Acute Kidney Injury; Anemia; Bicarbonates; Calcium; Child, Preschool; Dehydration; Furosem

1973
The effect of mefruside on plasma and muscle electrolytes and blood pressure in normal subjects and in patients with essential hypertension.
    Acta medica Scandinavica, 1973, Volume: 194, Issue:5

    Topics: Adult; Aged; Bicarbonates; Blood; Blood Glucose; Blood Pressure; Blood Proteins; Body Water; Body We

1973
Peripheral blood flow and metabolic control in juvenile diabetes.
    Diabetologia, 1974, Volume: 10, Issue:3

    Topics: Adipose Tissue; Adolescent; Adult; Bicarbonates; Blood Flow Velocity; Blood Glucose; Diabetes Compli

1974
Cardiovascular abnormalities following tricyclic antidepressant drug overdosage.
    Drugs, 1974, Volume: 7, Issue:5

    Topics: Acidosis; Antidepressive Agents; Arrhythmias, Cardiac; Bicarbonates; Bradycardia; Heart Rate; Humans

1974
Quadric analysis in the preoperative distinction between patients with and without adrenocortical tumors in hypertension with aldosterone excess and low plasma renin.
    American heart journal, 1971, Volume: 82, Issue:5

    Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adult; Aldosterone; Bicarbonates; Blood Pr

1971
[Treatment of acute glomerulonephritis].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. 1. Abt. Medizinisch-hygienische Bakteriologie, Virusforschung und Parasitologie. Originale, 1970, Volume: 214, Issue:3

    Topics: Acute Disease; Anuria; Bicarbonates; Brain Diseases; Child; Child, Preschool; Diet Therapy; Glomerul

1970
Cerebral spinal fluid studies in eclampsia.
    American journal of obstetrics and gynecology, 1972, Feb-15, Volume: 112, Issue:4

    Topics: Bicarbonates; Cerebrospinal Fluid; Chlorides; Eclampsia; Female; Hematocrit; Humans; Hypertension; N

1972
Acute pernicious beriberi heart disease.
    Chest, 1972, Volume: 61, Issue:5

    Topics: Acidosis; Acute Disease; Adult; Alcoholism; Beriberi; Bicarbonates; Cardiac Output; Cardiomyopathies

1972
Restoration of autoregulation of cerebral blood flow by hypocapnia.
    Neurology, 1972, Volume: 22, Issue:3

    Topics: Aged; Bicarbonates; Blood Pressure; Brain Neoplasms; Carbon Dioxide; Cerebrovascular Circulation; Ce

1972
Hypertension and drinking water. A pilot statewide ecological study in Colorado.
    Journal of chronic diseases, 1971, Volume: 23, Issue:8

    Topics: Adult; Bicarbonates; Chlorides; Colorado; Geography; Humans; Hypertension; Iron; Magnesium; Male; Mi

1971
Serum electrolytes in hypertension in Nigerians.
    Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 34, Issue:1

    Topics: Adult; Aged; Bicarbonates; Chlorides; Creatinine; Female; Humans; Hypertension; Male; Mathematics; M

1971
Hypertension and severe hyperkalaemia associated with suppression of renin and aldosterone and completely reversed by dietary sodium restriction.
    Australasian annals of medicine, 1970, Volume: 19, Issue:4

    Topics: Aldosterone; Ammonia; Bicarbonates; Blood Urea Nitrogen; Child; Chlorides; Creatinine; Diet, Sodium-

1970
Sodium homeostasis, salt appetite, and hypertension.
    Circulation research, 1970, Volume: 27

    Topics: Aldosterone; Animals; Anxiety; Appetite; Bicarbonates; Diet; Diet, Sodium-Restricted; Female; Food A

1970
Increased calcium excretion after saline administration to hypertensive subjects.
    The Journal of laboratory and clinical medicine, 1971, Volume: 77, Issue:2

    Topics: Adult; Bicarbonates; Calcium; Creatinine; Humans; Hypertension; Infusions, Parenteral; Kidney Tubule

1971
The importance of the cerebrospinal fluid acid-base status in the treatment of unconscious patients with brain lesions.
    Acta anaesthesiologica Scandinavica, 1968, Volume: 12, Issue:2

    Topics: Acid-Base Equilibrium; Acidosis; Adolescent; Adult; Aged; Bicarbonates; Brain Diseases; Carbon Dioxi

1968
[Studies on hypertension. 2. Influence of acid-base imbalance on the distribution of electrolytes and its relationship to hemodynamics].
    Japanese circulation journal, 1968, Volume: 32, Issue:9

    Topics: Acid-Base Equilibrium; Acidosis; Adult; Aged; Alkalosis; Arteries; Bicarbonates; Blood Pressure; Chl

1968
Furosemide in the treatment of acute post-streptococcal glomerulonephritis.
    Southern medical journal, 1969, Volume: 62, Issue:2

    Topics: Bicarbonates; Blood Pressure Determination; Blood Urea Nitrogen; Child; Chlorides; Creatinine; Edema

1969
[On the management of renal acidosis using sodium bicarbonate and ethacrynic acid].
    Deutsche medizinische Wochenschrift (1946), 1969, Jul-04, Volume: 94, Issue:27

    Topics: Acidosis, Renal Tubular; Acute Kidney Injury; Adult; Bicarbonates; Blood Pressure; Body Weight; Etha

1969
Hyperkalemia, hypertension and systemic acidosis without renal failure associated with a tubular defect in potassium excretion.
    The American journal of medicine, 1969, Volume: 47, Issue:3

    Topics: Acetazolamide; Acidosis, Renal Tubular; Adolescent; Adult; Aminohippuric Acids; Bicarbonates; Blood

1969
Biochemical effects of short-term treatment with carbenoxolone disodium.
    British journal of pharmacology and chemotherapy, 1966, Volume: 26, Issue:2

    Topics: Adolescent; Adult; Aged; Bicarbonates; Digestive System; Female; Gastric Mucosa; Gastrointestinal Di

1966