Page last updated: 2024-10-18

hydrogen carbonate and Ataxia with Lactic Acidosis

hydrogen carbonate has been researched along with Ataxia with Lactic Acidosis in 2 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Research Excerpts

ExcerptRelevanceReference
" The partial correction of lactic acidosis with oral sodium bicarbonate chronic therapy may result in a slow evolution of the clinical symptoms."3.68Congenital lactic acidosis due to a defect of pyruvate dehydrogenase complex (E1). Clinical, biochemical, nerve biopsy study and effect of therapy. ( Dotti, MT; Fabrizi, GM; Federico, A; Guazzi, GC; Malandrini, A; Massimo, L; Palmeri, S; Robinson, BH, 1990)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Neiberger, RE1
George, JC1
Perkins, LA1
Theriaque, DW1
Hutson, AD1
Stacpoole, PW1
Federico, A1
Dotti, MT1
Fabrizi, GM1
Palmeri, S1
Massimo, L1
Robinson, BH1
Malandrini, A1
Guazzi, GC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pharmacotoxicology of Trichloroethylene Metabolites: Short-term Effect of DCA on in Vivo Tyrosine Catabolism and MAAI Expression[NCT00865514]2 participants (Actual)Interventional2011-08-31Terminated (stopped due to Difficulty in obtaining the solution from the compounding pharmacies caused a two year delay in start-up; the funding ended prior to study completion.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for hydrogen carbonate and Ataxia with Lactic Acidosis

ArticleYear
Renal manifestations of congenital lactic acidosis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2002, Volume: 39, Issue:1

    Topics: Acidosis, Lactic; Adolescent; Adult; Bicarbonates; Blood Urea Nitrogen; Calcium; Child; Child, Presc

2002
Congenital lactic acidosis due to a defect of pyruvate dehydrogenase complex (E1). Clinical, biochemical, nerve biopsy study and effect of therapy.
    European neurology, 1990, Volume: 30, Issue:3

    Topics: Acidosis, Lactic; Bicarbonates; Biopsy; Brain Diseases, Metabolic; Child; Fibroblasts; Humans; Leigh

1990