hydrogen carbonate has been researched along with Alkalosis, Respiratory in 150 studies
Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.
Alkalosis, Respiratory: A state due to excess loss of carbon dioxide from the body. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sodium bicarbonate has been recommended for the treatment of arrhythmias induced by tricyclic antidepressants." | 7.67 | Use of sodium bicarbonate to treat tricyclic antidepressant-induced arrhythmias in a patient with alkalosis. ( Hall, KW; Molloy, DW; Penner, SB; Rabson, J, 1984) |
| "We present a 19-month-old boy with a history of asthma who presented to the pediatric emergency department with noisy breathing and tachypnea partially responsive to albuterol." | 3.76 | A 19-month-old boy with recurrent respiratory distress. ( Cross, KP; Herr, SM; Randell, KA, 2010) |
| " Two sets of experimental data, derived from two different methods of inducing anemia, were used: repetitive doses of phenylhydrazine (PHZ) and bleeding (BL)." | 3.70 | Acid-base analysis during experimental anemia in rats. ( Alfaro, V; Palacios, L; Pesquero, J, 2000) |
| "Under metabolic-balance conditions, we used altitude-induced hypobaric hypoxia to produce chronic hypocapnia in nine normal young men, five of whom received ammonium chloride daily to cause metabolic acidosis (the mean [+/- SE] steady-state plasma bicarbonate level in these five was 12." | 3.68 | Chronic respiratory alkalosis. The effect of sustained hyperventilation on renal regulation of acid-base equilibrium. ( Beeler, I; Hertner, D; Hulter, HN; Krapf, R, 1991) |
| "Sodium bicarbonate has been recommended for the treatment of arrhythmias induced by tricyclic antidepressants." | 3.67 | Use of sodium bicarbonate to treat tricyclic antidepressant-induced arrhythmias in a patient with alkalosis. ( Hall, KW; Molloy, DW; Penner, SB; Rabson, J, 1984) |
| "5% sodium bicarbonate (NaHCO3) in the diet of birds subjected to chronic heat stress enhanced body weight gain by 9% even though it tended (P less than ." | 3.67 | Chronic heat stress and respiratory alkalosis: occurrence and treatment in broiler chicks. ( Arp, SC; Breazile, JE; Owens, FN; Sangiah, S; Smith, MO; Teeter, RG, 1985) |
| "Hyperventilation-induced respiratory alkalosis can enhance WAnT cycling sprint performance well in the magnitude of what is seen after successful bicarbonate ingestion." | 2.82 | Enhancement on Wingate Anaerobic Test Performance With Hyperventilation. ( Beneke, R; Böning, D; Hütler, M; Leithäuser, RM, 2016) |
| "Among patients with COPD receiving invasive mechanical ventilation, the use of acetazolamide, compared with placebo, did not result in a statistically significant reduction in the duration of invasive mechanical ventilation." | 2.82 | Effect of Acetazolamide vs Placebo on Duration of Invasive Mechanical Ventilation Among Patients With Chronic Obstructive Pulmonary Disease: A Randomized Clinical Trial. ( Bornstain, C; Clavel, M; Djibre, M; Duguet, A; Esvan, M; Faisy, C; Gacouin, A; Gibot, S; Heming, N; Katsahian, S; Lerolle, N; Meziani, F; Planquette, B; Rabbat, A; Ricard, JD; Ricome, JL; Sanchez, O; Schneider, F; Urien, S, 2016) |
| "To determine the effects of respiratory acidosis and alkalosis by mechanical ventilation on the onset, duration, and recovery times of vecuronium." | 2.70 | Respiratory acidosis prolongs, while alkalosis shortens, the duration and recovery time of vecuronium in humans. ( Iwasaki, H; Namiki, A; Takahashi, H; Yamauchi, M, 2002) |
| "Several disorders can mimic renal tubular acidosis, and these must be appropriately diagnosed to prevent inadvertent and inappropriate application of alkali therapy." | 2.58 | Pseudo-Renal Tubular Acidosis: Conditions Mimicking Renal Tubular Acidosis. ( Uduman, J; Yee, J, 2018) |
| "Severe respiratory alkalosis is a life-threatening condition, as it induces hypo- calcaemia and extreme adrenergic sensitivity leading to cerebral and myocardial vasoconstriction." | 1.72 | [Severe respiratory alkalosis due to psychogenic hyperventilation. Report of one case]. ( Juanet, C; Romero, J; Sepúlveda, RA; Sepúlveda, S, 2022) |
| "In patients with COPD exacerbation and hypercapnia, the development of sufficient metabolic compensation and adequate renal function significantly decreases mortality." | 1.35 | Relationship of metabolic alkalosis, azotemia and morbidity in patients with chronic obstructive pulmonary disease and hypercapnia. ( Bal, C; Dagli, CE; Oztuna, F; Ucgun, I; Yildirim, H, 2008) |
| "The pathophysiological consequences of febrile seizures have been extensively studied in rat pups exposed to hyperthermia." | 1.33 | Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis. ( Kaila, K; Mackie, K; Rivera, C; Salmen, B; Schmitz, D; Schuchmann, S; Sipilä, ST; Vanhatalo, S; Voipio, J, 2006) |
| "In medullary raphe neurones, respiratory acidosis (5%--> 9% CO(2)) caused a rapid fall in pH(i) (DeltapH(i) approximately 0." | 1.32 | Effect of extracellular acid-base disturbances on the intracellular pH of neurones cultured from rat medullary raphe or hippocampus. ( Boron, WF; Bouyer, P; Bradley, SR; Richerson, GB; Wang, W; Zhao, J, 2004) |
| "We suggest that respiratory alkalosis (hypocapnia) of Leigh syndrome patients with SURF1 mutations results from compulsory hyperventilation and speculate that hypocapnia may contribute to Leigh-like brain damage in the SURF1-deficient patients as well as in other patients presenting with Leigh-like syndrome." | 1.31 | Compulsory hyperventilation and hypocapnia of patients with Leigh syndrome associated with SURF1 gene mutations as a cause of low serum bicarbonates. ( Karczmarewicz, E; Piekutowska-Abramczuk, DH; Popowska, E; Pronicka, E; Pronicki, M; Sykut-Cegielskâ, Y; Taybert, J, 2001) |
| "We have studied the effects of acute respiratory alkalosis (ARALK, hyperventilation) and acidosis (ARA, 8% CO2), chronic respiratory acidosis (CRA; 10% CO2 for 7-10 days), and subsequent recovery from CRA breathing air on loop of Henle (LOH) net bicarbonate flux (JHCO3) by in vivo tubule microperfusion in anesthetized rats." | 1.30 | The effects of respiratory alkalosis and acidosis on net bicarbonate flux along the rat loop of Henle in vivo. ( Capasso, G; Stidwell, R; Taylor, S; Unwin, R, 1997) |
| "Following CO2 treatment, respiratory alkalosis conditions returned." | 1.29 | Laying hen responses to acute heat stress and carbon dioxide supplementation: I. Blood gas changes and plasma lactate accumulation. ( Koelkebeck, KW; Odom, TW, 1994) |
| "In Group II (acute respiratory alkalosis), both PaCO2 and cisternal CSF PCO2 decreased by 10 mm Hg." | 1.29 | Quantitative cerebrospinal fluid acid-base balance in acute respiratory alkalosis. ( Adams, JM; Corbett, W; Javaheri, S; Wagner, K, 1994) |
| "In chronic respiratory alkalosis, on the other hand, plasma bicarbonate should fall by 0." | 1.28 | [Hypo- and hyperventilation: consequences for acid-base balance]. ( Krapf, R, 1991) |
| "Hypercapnia was induced in rats acutely (1-3 h) and chronically (4-5 d) by increasing inspired PCO2." | 1.28 | Delivery dependence of early proximal bicarbonate reabsorption in the rat in respiratory acidosis and alkalosis. ( Gennari, FJ; Maddox, DA; Santella, RN, 1991) |
| "Hypokalemia in respiratory alkalosis was associated with a decrease in the plasma norepinephrine concentration from the control level of 377 +/- 104 to 155 +/- 41 pg/ml (P less than 0." | 1.28 | Role of hormonal factors in plasma K alterations in acute respiratory and metabolic alkalosis in dogs. ( Hishida, A; Honda, N; Kimura, M; Ohishi, K; Suzuki, H, 1990) |
| "Metabolic alkalosis has previously been shown to have an antimagnesiuric influence." | 1.28 | Effects of systemic alkalosis on urinary magnesium excretion in the rat. ( Levin, M; Winaver, J, 1989) |
| "Sodium bicarbonate (5 mmol/kg) was infused over 10 min to the unanesthetized animals; observations were carried out over 90 min." | 1.27 | Influence of steady-state alterations in acid-base equilibrium on the fate of administered bicarbonate in the dog. ( Adrogué, HJ; Brensilver, J; Cohen, JJ; Madias, NE, 1983) |
| "These data suggest that, during respiratory acidosis and alkalosis, pHi is maintained in a qualitatively similar way in the jejunum, ileum, and colon with quantitatively greater or lesser changes in (HCO3)i." | 1.27 | Intestinal ion transport and intracellular pH during acute respiratory alkalosis and acidosis. ( Charney, AN; Kurtin, P, 1984) |
| "Decreases in systemic pH during respiratory acidosis caused equivalent increases in net water (54 +/- 8 microliters ." | 1.27 | Effect of systemic acid-base balance on ileal secretion. ( Charney, AN; Goldfarb, DS; Ingrassia, PM, 1987) |
| "Chronic respiratory alkalosis and acidosis, as well as the acute CO2 titrations, were produced in unanesthetized dogs within a large environmental chamber." | 1.27 | Influence of chronic respiratory acid-base disorders on acute CO2 titration curve. ( Adrogué, HJ; Madias, NE, 1985) |
| "Respiratory acidosis was induced by CO2 inhalations in 5 dogs, respiratory alkalosis by hyperventilation in 5 dogs, metabolic acidosis by intravenous(i." | 1.26 | Pancreatic tissue pH in experimental acidosis and alkalosis. ( Farkas, S; Halmágyi, G; Lantos, J; Molnár, Z, 1980) |
| "A primary respiratory alkalosis was also present in several patients." | 1.26 | Acid-base balance in continuous ambulatory peritoneal dialysis. ( Cupit, M; Haff, AC; Reichard, GA; Schleifer, CR; Sigler, MH; Teehan, BP, 1980) |
| "To compare metabolic with respiratory alkalosis 17 dogs were anesthetized with halothane and their VO2 response to respiratory alkalosis evaluated by hyperventilation." | 1.26 | Determinants of oxygen uptake during sodium bicarbonate infusion. ( Patterson, RW; Sullivan, SF, 1978) |
| "Metabloic alkalosis is due to loss of H+ (usually from stomach or kidneys) or ingestion of alkali." | 1.26 | Acute acid-base disorders. 2. Specific disturbances. ( Quintanilla, AP, 1976) |
| "Hyperaldosteronism, a disease entity influencing electrolytic changes and causing other pathophysiological effects, should be understood by the surgeon." | 1.24 | HOMEOSTATIC PROBLEMS IN GENERAL SURGERY. ( LUPPI, AP, 1965) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 112 (74.67) | 18.7374 |
| 1990's | 15 (10.00) | 18.2507 |
| 2000's | 10 (6.67) | 29.6817 |
| 2010's | 10 (6.67) | 24.3611 |
| 2020's | 3 (2.00) | 2.80 |
| Authors | Studies |
|---|---|
| Steele, AR | 1 |
| Ainslie, PN | 1 |
| Stone, R | 1 |
| Tymko, K | 1 |
| Tymko, C | 1 |
| Howe, CA | 1 |
| MacLeod, D | 1 |
| Anholm, JD | 1 |
| Gasho, C | 1 |
| Tymko, MM | 1 |
| Sepúlveda, RA | 1 |
| Romero, J | 1 |
| Sepúlveda, S | 1 |
| Juanet, C | 1 |
| Assadi, F | 1 |
| Bae, K | 1 |
| Jee, D | 1 |
| Uduman, J | 1 |
| Yee, J | 1 |
| Lomax, M | 1 |
| Kapus, J | 1 |
| Webb, S | 1 |
| Ušaj, A | 1 |
| Nadler, ST | 1 |
| Suri, J | 1 |
| Swenson, ER | 1 |
| Kościelska, M | 1 |
| Mieczkowski, M | 1 |
| Leithäuser, RM | 1 |
| Böning, D | 3 |
| Hütler, M | 1 |
| Beneke, R | 1 |
| Faisy, C | 1 |
| Meziani, F | 1 |
| Planquette, B | 1 |
| Clavel, M | 1 |
| Gacouin, A | 1 |
| Bornstain, C | 1 |
| Schneider, F | 1 |
| Duguet, A | 1 |
| Gibot, S | 1 |
| Lerolle, N | 1 |
| Ricard, JD | 1 |
| Sanchez, O | 1 |
| Djibre, M | 1 |
| Ricome, JL | 1 |
| Rabbat, A | 1 |
| Heming, N | 1 |
| Urien, S | 1 |
| Esvan, M | 1 |
| Katsahian, S | 1 |
| Cross, KP | 1 |
| Randell, KA | 1 |
| Herr, SM | 1 |
| Hidalgo, SF | 1 |
| Prieto de Paula, JM | 1 |
| Martin, NK | 1 |
| Gaffney, EA | 1 |
| Gatenby, RA | 1 |
| Gillies, RJ | 1 |
| Robey, IF | 1 |
| Maini, PK | 1 |
| LUPPI, AP | 1 |
| SCHWARTZ, WB | 1 |
| LEMIEUX, G | 1 |
| FALBRIARD, A | 1 |
| Bouyer, P | 1 |
| Bradley, SR | 1 |
| Zhao, J | 1 |
| Wang, W | 1 |
| Richerson, GB | 1 |
| Boron, WF | 1 |
| Kosch, M | 1 |
| Schaefer, RM | 1 |
| Schuchmann, S | 1 |
| Schmitz, D | 1 |
| Rivera, C | 1 |
| Vanhatalo, S | 1 |
| Salmen, B | 1 |
| Mackie, K | 1 |
| Sipilä, ST | 1 |
| Voipio, J | 1 |
| Kaila, K | 1 |
| Johnson, RA | 1 |
| Ucgun, I | 1 |
| Oztuna, F | 1 |
| Dagli, CE | 1 |
| Yildirim, H | 1 |
| Bal, C | 1 |
| Arvidsson, S | 1 |
| Häggendal, E | 1 |
| Winsö, I | 1 |
| Adrogué, HJ | 3 |
| Brensilver, J | 1 |
| Cohen, JJ | 2 |
| Madias, NE | 3 |
| Brobst, D | 2 |
| Molloy, DW | 1 |
| Penner, SB | 1 |
| Rabson, J | 1 |
| Hall, KW | 1 |
| Ackerman, GL | 1 |
| Arruda, JA | 3 |
| Batlle, DC | 1 |
| Itsarayoungyuen, K | 1 |
| Downer, M | 1 |
| Foley, R | 1 |
| Kurtzman, NA | 1 |
| Bettice, JA | 3 |
| Owens, D | 1 |
| Riley, S | 1 |
| Goodkin, DA | 1 |
| Krishna, GG | 1 |
| Narins, RG | 2 |
| Kurtin, P | 1 |
| Charney, AN | 2 |
| Massey, EW | 1 |
| Farkas, S | 1 |
| Lantos, J | 1 |
| Halmágyi, G | 1 |
| Molnár, Z | 1 |
| Langberg, H | 1 |
| Mathisen, O | 1 |
| Holdaas, H | 1 |
| Kiil, F | 1 |
| El Hadi, H | 1 |
| Sykes, AH | 1 |
| Oberleithner, H | 1 |
| Greger, R | 1 |
| Lang, F | 1 |
| DuBose, TD | 1 |
| Abendschein, DR | 1 |
| Mines, AH | 1 |
| Goerke, JR | 1 |
| Kellogg, RH | 1 |
| Bia, M | 1 |
| Thier, SO | 1 |
| Dordoni, PL | 1 |
| De Cosmo, G | 1 |
| Bondoli, A | 2 |
| Schleifer, CR | 1 |
| Teehan, BP | 1 |
| Reichard, GA | 1 |
| Sigler, MH | 1 |
| Cupit, M | 1 |
| Haff, AC | 1 |
| Milhorn, HT | 1 |
| Koushanpour, E | 1 |
| McAuley, JW | 1 |
| Koelkebeck, KW | 1 |
| Odom, TW | 1 |
| Javaheri, S | 2 |
| Corbett, W | 1 |
| Wagner, K | 1 |
| Adams, JM | 1 |
| Moreau, R | 1 |
| Hadengue, A | 1 |
| Soupison, T | 1 |
| Mamzer, MF | 1 |
| Kirstetter, P | 1 |
| Saraux, JL | 1 |
| Assous, M | 1 |
| Roche-Sicot, J | 1 |
| Sicot, C | 1 |
| Ranta-Knuuttila, T | 1 |
| Mustonen, H | 1 |
| Kivilaakso, E | 1 |
| Lückermann, M | 1 |
| Trapp, S | 1 |
| Ballanyi, K | 1 |
| Unwin, R | 1 |
| Stidwell, R | 1 |
| Taylor, S | 1 |
| Capasso, G | 1 |
| Schlichtig, R | 1 |
| Grogono, AW | 1 |
| Severinghaus, JW | 1 |
| Pesquero, J | 1 |
| Alfaro, V | 1 |
| Palacios, L | 1 |
| Ishibashi, T | 1 |
| Kubota, K | 1 |
| Himeno, M | 1 |
| Matsubara, T | 1 |
| Hori, T | 1 |
| Ozaki, K | 1 |
| Yamozoe, M | 1 |
| Aizawa, Y | 1 |
| Yoshida, J | 1 |
| Nishio, M | 1 |
| Pronicka, E | 1 |
| Piekutowska-Abramczuk, DH | 1 |
| Popowska, E | 1 |
| Pronicki, M | 1 |
| Karczmarewicz, E | 1 |
| Sykut-Cegielskâ, Y | 1 |
| Taybert, J | 1 |
| Yamauchi, M | 1 |
| Takahashi, H | 1 |
| Iwasaki, H | 1 |
| Namiki, A | 1 |
| Höhne, C | 1 |
| Boemke, W | 1 |
| Schleyer, N | 1 |
| Francis, RC | 1 |
| Krebs, MO | 1 |
| Kaczmarczyk, G | 1 |
| Sodipo, JO | 1 |
| Lee, DC | 1 |
| Morris, LE | 1 |
| Smithline, N | 1 |
| Choma, L | 1 |
| Späth, G | 1 |
| Albert, MS | 1 |
| Haskins, SC | 1 |
| Martinez-Maldonado, M | 1 |
| Sanchez-Montserrat, R | 1 |
| Förster, H | 1 |
| Kazemi, H | 3 |
| Patterson, RW | 1 |
| Sullivan, SF | 1 |
| Fadel, HE | 1 |
| Northrop, G | 1 |
| Misenhimer, HR | 1 |
| Harp, RJ | 1 |
| Buchanan, N | 1 |
| Kundig, H | 1 |
| Eyberg, C | 1 |
| Hornbein, TF | 1 |
| Pavlin, EG | 1 |
| Plum, F | 1 |
| Siesjo, BK | 2 |
| Howorth, PJ | 1 |
| Wichser, J | 1 |
| Emmett, M | 1 |
| Latimer, RD | 1 |
| Laszlo, G | 1 |
| Hirschman, GH | 1 |
| Chan, JC | 1 |
| Chesney, RW | 1 |
| McPherson, E | 1 |
| Hall, D | 1 |
| Segar, WE | 1 |
| Quintanilla, AP | 1 |
| Meyer, JG | 1 |
| Gougoux, A | 1 |
| Kaehny, WD | 1 |
| Kuhn, MM | 1 |
| Busse, MW | 1 |
| Scholz, J | 1 |
| Maassen, N | 1 |
| Krapf, R | 2 |
| Beeler, I | 1 |
| Hertner, D | 1 |
| Hulter, HN | 1 |
| Santella, RN | 1 |
| Maddox, DA | 1 |
| Gennari, FJ | 1 |
| Suzuki, H | 1 |
| Hishida, A | 1 |
| Ohishi, K | 1 |
| Kimura, M | 1 |
| Honda, N | 1 |
| Gonzalez, NC | 1 |
| Albrecht, T | 1 |
| Sullivan, LP | 1 |
| Clancy, RL | 1 |
| Blot-Chabaud, M | 1 |
| Dumont, M | 1 |
| Corbic, M | 1 |
| Erlinger, S | 1 |
| Al-Awqati, Q | 1 |
| Levin, M | 1 |
| Winaver, J | 1 |
| Bajaj, AK | 1 |
| Woosley, RL | 1 |
| Roden, DM | 1 |
| Ruiz, OS | 1 |
| Talor, Z | 1 |
| Hobbs, J | 1 |
| LaGrange, BM | 1 |
| Hood, VL | 1 |
| Kassirer, JP | 2 |
| Teeter, RG | 1 |
| Smith, MO | 1 |
| Owens, FN | 1 |
| Arp, SC | 1 |
| Sangiah, S | 1 |
| Breazile, JE | 1 |
| Jehle, D | 1 |
| Harchelroad, F | 1 |
| Breyer, MD | 1 |
| Kokko, JP | 1 |
| Jacobson, HR | 1 |
| York, K | 1 |
| Bengele, HH | 1 |
| McNamara, ER | 1 |
| Schwartz, JH | 1 |
| Alexander, EA | 1 |
| Elms, JJ | 1 |
| Norris, SH | 1 |
| Goldfarb, DS | 1 |
| Ingrassia, PM | 1 |
| Walmsley, RN | 1 |
| White, GH | 1 |
| Tannen, RL | 1 |
| Gerrits, L | 1 |
| Rothe, KF | 1 |
| Schorer, R | 1 |
| Katz, RM | 1 |
| Van Leuven, F | 1 |
| Weyne, J | 1 |
| Rodríguez Navarro, I | 1 |
| Del Villar Galán, JL | 1 |
| Fermoso García, J | 1 |
| Alguire, PC | 1 |
| Bailie, MD | 1 |
| Weaver, WJ | 1 |
| Taylor, DG | 1 |
| Hook, JB | 1 |
| Schweigart, U | 1 |
| Nutz, V | 1 |
| Stegemann, J | 1 |
| Catangay, PA | 1 |
| Géraud, J | 1 |
| Rascol, A | 1 |
| Bes, A | 1 |
| Guiraud, B | 1 |
| Géraud, G | 1 |
| Hudson, HE | 1 |
| Harber, PI | 1 |
| Smith, TC | 1 |
| Mitchell, JH | 1 |
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| Bobrovskaia, AN | 1 |
| Klahr, S | 1 |
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| Davies, DG | 2 |
| Gurtner, GH | 2 |
| Shore, NS | 1 |
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| Magalini, SI | 1 |
| Scrascia, E | 1 |
| Scheidemandel, V | 1 |
| Wirtzfeld, A | 1 |
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| Grängsjö, G | 1 |
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| Cherniaeva, TE | 1 |
| Arroyo, JL | 1 |
| El Busto, J | 1 |
| Torán, I | 1 |
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| Ortiz de Landázuri, E | 1 |
| King, LR | 1 |
| McLaurin, RL | 1 |
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| Gamble, JL | 1 |
| Zuromskis, PJ | 1 |
| Ginsberg, RL | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Trial to Evaluate Effectiveness of Acetazolamide in COPD Patients Developing Metabolic Alkalosis During Invasive Mechanical Ventilation[NCT01627639] | Phase 4 | 380 participants (Actual) | Interventional | 2011-10-31 | Completed | ||
| Phase 3 Trial of Coenzyme Q10 in Mitochondrial Disease[NCT00432744] | Phase 3 | 24 participants (Actual) | Interventional | 2007-01-31 | Completed | ||
| Comparative Analysis Between Ringer's Lactate vs Acetate Containing Balanced Crystalloid Solution (Plasma Lyte-A) as Cardiopulmonary Bypass Prime[NCT03043131] | Phase 3 | 60 participants (Anticipated) | Interventional | 2017-02-10 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The McMaster Gross Motor Function is a validated scale ranging from 0 to 100 (the higher the better). Since there was the possibility of a subject becoming totally disabled our FDA peer reviewed design called for its use as follows: If the subject completed both periods, the score was calculated as the difference in scores between the end of Period 2 (at 12 months) minus that at the end of Period 1 (6 months). If a subject became totally disabled, this difference was considered as plus infinity if it occurred in period 1 (Penalizes period 1), and minus infinity if it occurred in Period 2 (Penalizes period 2). The two treatments were compared via the Wilcoxon test, and the effect size was estimated using Kendall's Tau-B. This is interpreted in a similar manner to correlation with positive values favoring COQenzyme10 and negative values favoring placebo. One of the links in this report is to the the GMFM scale and how it is scored. A link to the instrument is included. (NCT00432744)
Timeframe: Taken at 6 and 12 Months
| Intervention | units on a scale (Median) |
|---|---|
| Placebo First | -0.002 |
| CoenzymeQ10 Frist | -0.12 |
This is a multivariate analysis of the first two outcomes: Period 2 minus Period 1 GMFM88 and Peds Quality of Life, analyzed as follows: First, to be in the analysis, subjects must contribute at least one of these endpoints. Second, if the subject became totally disabled during period 1, the difference was defined as + infinity, (highest possible evidence favoring period 2), and if the subject became totally disabled in period 2, the subject was scored as - infinity (highest possible evidence favoring period 1). Period 2 minus period 1 differences were ranked form low to high with missing values scores at the mid-rank. The Hotelling T-square was computed on these ranks and the P-value was obtained from 100,000 rerandomizations as the fraction of rerandomizations with T-sq at least as large as that observed. (NCT00432744)
Timeframe: end of 12 month minus end of 6 month difference.
| Intervention | participants (Number) |
|---|---|
| Placebo First | 7 |
| CoenzymeQ10 Frist | 8 |
"The Pediatric Quality of Life Scale is a validated scale ranging from 0 to 100 (the higher the better). Since there was the possibility of a subject becoming totally disabled our FDA peer reviewed design called for its use as follows: If the subject completed both periods, the score was calculated as the difference in scores between the end of Period 2 (at 12 months) minus that at the end of Period 1 (6 months). If a subject became totally disabled, this difference was considered as plus infinity if it occurred in period 1 (Penalizes period 1), and minus infinity if it occurred in Period 2 (Penalizes period 2). The two treatments were compared via the Wilcoxon test, and the effect size was estimated using Kendall's Tau-B. This is interpreted in a similar manner to correlation with positive values favoring COQenzyme10 and negative values favoring placebo. Goggle pedsQL and Mapi to browse the copyrighted manual. A link to the instrument is included." (NCT00432744)
Timeframe: At 6 and 12 Months
| Intervention | units on a scale (Median) |
|---|---|
| Placebo First | -1.1 |
| CoenzymeQ10 Frist | -11.9 |
16 reviews available for hydrogen carbonate and Alkalosis, Respiratory
| Article | Year |
|---|---|
Pseudo-Renal Tubular Acidosis: Conditions Mimicking Renal Tubular Acidosis.
Topics: Acid-Base Equilibrium; Acidosis, Renal Tubular; Alkalosis, Respiratory; Bicarbonates; Diagnosis, Dif | 2018 |
[Alkalosis].
Topics: Alkalosis; Alkalosis, Respiratory; Bicarbonates; Carbon Dioxide; Diagnosis, Differential; Diuretics; | 2013 |
Respiratory alkalosis: a quick reference.
Topics: Alkalosis, Respiratory; Animals; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Hydrogen-Ion Conc | 2008 |
Pathophysiologic and adaptive changes in acid-base disorders.
Topics: Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Animals; Bi | 1983 |
Disorders of acid-base relationships in the cerebrospinal fluid: a review.
Topics: Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Alkalosis, Respiratory; Bicarbonates; Brain Di | 1980 |
Human PaCO2 and standard base excess compensation for acid-base imbalance.
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Alkalosis, Respiratory; Bicarbonates; Carbon Dioxide; | 1998 |
An overview of acid-base physiology.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Animals; | 1977 |
Bicarbonate.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, R | 1986 |
Exercise induced bronchospasm in childhood.
Topics: Acidosis; Alkalosis, Respiratory; Asthma; Autacoids; Bicarbonates; Bradykinin; Bronchial Spasm; Carb | 1970 |
[Constants of acid-base equilibrium in the cerebrospinal fluid].
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Bicarbona | 1973 |
[The cerebrospinal fluid in disturbances of plasma acid-base equilibrium].
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Animals; | 1973 |
The effects of acid-base disturbances on cardiovascular and pulmonary function.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Altitude; | 1972 |
Acid base, blood gas, and electrolyte balances.
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Bicarbonates; Blood | 1972 |
An approach to clinical disorders of acid-base balance.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Ammonia; | 1974 |
Serious acid-base disorders.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Acute Disease; Alkalosis; Alkalosis, Respira | 1974 |
Monitoring in anesthesia. Acid-base monitoring.
Topics: Acid-Base Equilibrium; Acidosis; Alkalosis; Alkalosis, Respiratory; Anesthesiology; Apnea; Bicarbona | 1973 |
5 trials available for hydrogen carbonate and Alkalosis, Respiratory
| Article | Year |
|---|---|
Enhancement on Wingate Anaerobic Test Performance With Hyperventilation.
Topics: Acid-Base Equilibrium; Adult; Alkalosis, Respiratory; Anaerobic Threshold; Bicarbonates; Biomarkers; | 2016 |
Effect of Acetazolamide vs Placebo on Duration of Invasive Mechanical Ventilation Among Patients With Chronic Obstructive Pulmonary Disease: A Randomized Clinical Trial.
Topics: Acetazolamide; Aged; Alkalosis, Respiratory; Bicarbonates; Carbon Dioxide; Carbonic Anhydrase Inhibi | 2016 |
Respiratory acidosis prolongs, while alkalosis shortens, the duration and recovery time of vecuronium in humans.
Topics: Abdomen; Acidosis, Respiratory; Alkalosis, Respiratory; Bicarbonates; Carbon Dioxide; Humans; Hydrog | 2002 |
Respiratory depression from alkalosis and opioid interaction in man.
Topics: Adult; Alkalosis, Respiratory; Analgesics; Anesthesia, Intravenous; Bicarbonates; Blood; Carbon Diox | 1974 |
[Acid-base parameters in postoperative infusion therapy].
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Bicarbona | 1973 |
129 other studies available for hydrogen carbonate and Alkalosis, Respiratory
| Article | Year |
|---|---|
Global REACH 2018: Characterizing Acid-Base Balance Over 21 Days at 4,300 m in Lowlanders.
Topics: Acclimatization; Acid-Base Equilibrium; Alkalosis, Respiratory; Altitude; Bicarbonates; Female; Huma | 2022 |
[Severe respiratory alkalosis due to psychogenic hyperventilation. Report of one case].
Topics: Adrenergic Agents; Adult; Alkalosis, Respiratory; Benzodiazepines; Bicarbonates; COVID-19; Female; H | 2022 |
Urine anion gap can differentiate respiratory alkalosis from metabolic acidosis in the absence of blood gas results.
Topics: Acid-Base Equilibrium; Acidosis; Alkalosis; Alkalosis, Respiratory; Bicarbonates; Humans; Hydrogen-I | 2023 |
Hyperventilation Syndrome and Sustained Hyperchloremia After Kidney Transplant: Time-Sequence Swing of Acid-Base Interpretation.
Topics: Acid-Base Equilibrium; Acidosis; Adult; Alkalosis, Respiratory; Bicarbonates; Biomarkers; Chlorides; | 2018 |
The effect of inspiratory muscle fatigue on acid-base status and performance during race-paced middle-distance swimming.
Topics: Acid-Base Equilibrium; Alkalosis, Respiratory; Athletic Performance; Bicarbonates; Carbon Dioxide; F | 2019 |
How Basic Can You Be?
Topics: Acidosis, Lactic; Alkalosis; Alkalosis, Respiratory; Bicarbonates; Diagnosis, Differential; Humans; | 2019 |
A 19-month-old boy with recurrent respiratory distress.
Topics: Acid-Base Equilibrium; Albuterol; Alkalosis, Respiratory; Aspirin; Asthma; Bicarbonates; Bites, Huma | 2010 |
[Acute topiramate intoxication: cause of metabolic acidosis and central hyperventilation].
Topics: Acidosis; Alkalosis, Respiratory; Bicarbonates; Brain; Carbon Dioxide; Carbonic Anhydrase Inhibitors | 2011 |
A mathematical model of tumour and blood pHe regulation: The HCO3-/CO2 buffering system.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Algorithms; Alkalosis; Alkalosis, Respirator | 2011 |
HOMEOSTATIC PROBLEMS IN GENERAL SURGERY.
Topics: Acidosis, Respiratory; Alkalosis, Respiratory; Bicarbonates; Carbon Dioxide; Dehydration; Homeostasi | 1965 |
Renal reabsorption of bicarbonate during acute respiratory alkalosis.
Topics: Alkalosis; Alkalosis, Respiratory; Bicarbonates; Humans; Kidney; Renal Reabsorption | 1959 |
Effect of extracellular acid-base disturbances on the intracellular pH of neurones cultured from rat medullary raphe or hippocampus.
Topics: Acidosis, Respiratory; Alkalosis, Respiratory; Animals; Bicarbonates; Carbon Dioxide; Cells, Culture | 2004 |
[Diagnosis and treatment of disordered acid-base balance].
Topics: Acid-Base Imbalance; Acidosis, Respiratory; Alkalosis, Respiratory; Bicarbonates; Carbon Dioxide; Di | 2005 |
Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis.
Topics: Alkalosis, Respiratory; Animals; Bicarbonates; Body Temperature; Brain; Carbon Dioxide; Disease Mode | 2006 |
Relationship of metabolic alkalosis, azotemia and morbidity in patients with chronic obstructive pulmonary disease and hypercapnia.
Topics: Aged; Alkalosis, Respiratory; APACHE; Bicarbonates; Creatinine; Female; Humans; Hydrogen-Ion Concent | 2008 |
Influence on cerebral blood flow of infusion of sodium bicarbonate during respiratory acidosis and alkalosis in the dog.
Topics: Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Animals; Bicarbonates; Carbon Dioxide; Cer | 1981 |
Influence of steady-state alterations in acid-base equilibrium on the fate of administered bicarbonate in the dog.
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Alkalosis, Respiratory; Animals; Bicarbonates; Carbon | 1983 |
Use of sodium bicarbonate to treat tricyclic antidepressant-induced arrhythmias in a patient with alkalosis.
Topics: Adult; Alkalosis; Alkalosis, Respiratory; Arrhythmias, Cardiac; Bicarbonates; Electrocardiography; F | 1984 |
Acid-base and electrolyte imbalance in respiratory failure.
Topics: Acid-Base Imbalance; Acidosis, Respiratory; Alkalosis, Respiratory; Animals; Bicarbonates; Carbon Di | 1983 |
Suppression of distal urinary acidification after recovery from chronic hypocapnia.
Topics: Alkalosis, Respiratory; Animals; Bicarbonates; Carbon Dioxide; Electrolytes; Hydrogen-Ion Concentrat | 1983 |
The effects of hypocapnia on intracellular pH and bicarbonate.
Topics: Acid-Base Equilibrium; Alkalosis, Respiratory; Animals; Bicarbonates; Body Fluids; Carbon Dioxide; H | 1984 |
The role of the anion gap in detecting and managing mixed metabolic acid-base disorders.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Alkalosis; Alkalosis, Respiratory; Anti-Bacter | 1984 |
Intestinal ion transport and intracellular pH during acute respiratory alkalosis and acidosis.
Topics: Acidosis, Respiratory; Alkalosis, Respiratory; Animals; Bicarbonates; Biological Transport; Chloride | 1984 |
Pancreatic tissue pH in experimental acidosis and alkalosis.
Topics: Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Animals; Bicarbonates; Blood; Ca | 1980 |
Filtered bicarbonate and plasma pH as determinants of renal bicarbonate reabsorption.
Topics: Alkalosis; Alkalosis, Respiratory; Animals; Bicarbonates; Carbon Dioxide; Creatinine; Dogs; Ethacryn | 1981 |
Thermal panting and respiratory alkalosis in the laying hen.
Topics: Alkalosis, Respiratory; Animals; Bicarbonates; Carbon Dioxide; Chickens; Female; Oviposition; Poultr | 1982 |
The effect of respiratory and metabolic acid-base changes on ionized calcium concentration: in vivo and in vitro experiments in man and rat.
Topics: Acidosis; Acidosis, Respiratory; Adult; Alkalosis; Alkalosis, Respiratory; Animals; Bicarbonates; Ca | 1982 |
Clinical approach to patients with acid-base disorders.
Topics: Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Bicarbonate | 1983 |
Changes in plasma potassium concentration during acute acid-base disturbances.
Topics: Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Acute Disease; Alkalosis; Alkalosis, Respirato | 1981 |
Acid-base balance in the dog.
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Alkalosis, Respiratory; Animals; Bicarbonates; Dogs | 1982 |
Mixed acid base disturbances: a clinical approach.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis, Respiratory; Alkalosis, Respiratory; Bicarbona | 1981 |
[Control of acid-base equilibrium in open-heart surgery].
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Alkalosis, Respiratory; Bicarbonates; Cardiac | 1981 |
Acid-base balance in continuous ambulatory peritoneal dialysis.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acid-Base Imbalance; Acidosis, Respiratory; Alkalosis, Respira | 1980 |
Understanding arterial blood gases.
Topics: Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Bicarbonate | 1980 |
Systems analysis of renal response to increasing levels of acute forced hyperventilation in dogs.
Topics: Acid-Base Imbalance; Alkalosis, Respiratory; Animals; Bicarbonates; Carbon Dioxide; Computers; Dogs; | 1980 |
Laying hen responses to acute heat stress and carbon dioxide supplementation: I. Blood gas changes and plasma lactate accumulation.
Topics: Acid-Base Equilibrium; Acute Disease; Alkalosis, Respiratory; Animals; Bicarbonates; Body Temperatur | 1994 |
Quantitative cerebrospinal fluid acid-base balance in acute respiratory alkalosis.
Topics: Acid-Base Equilibrium; Acute Disease; Alkalosis, Respiratory; Animals; Bicarbonates; Carbon Dioxide; | 1994 |
Arterial and mixed venous acid-base status in patients with cirrhosis. Influence of liver failure.
Topics: Alkalosis, Respiratory; Bicarbonates; Blood Gas Analysis; Female; Humans; Hydrogen-Ion Concentration | 1993 |
High systemic HCO3(-) and topical 16,16-dimethyl-PGE2 protect gastric mucosa against luminal acid by enhancing its preepithelial buffer capacity.
Topics: 16,16-Dimethylprostaglandin E2; Alkalosis; Alkalosis, Respiratory; Analysis of Variance; Animals; An | 1996 |
GABA- and glycine-mediated fall of intracellular pH in rat medullary neurons in situ.
Topics: Alkalosis, Respiratory; Animals; Bicarbonates; Carbon Dioxide; Carbonic Acid; Chloride Channels; Fem | 1997 |
The effects of respiratory alkalosis and acidosis on net bicarbonate flux along the rat loop of Henle in vivo.
Topics: Acidosis, Respiratory; Alkalosis, Respiratory; Analysis of Variance; Animals; Bicarbonates; Blood Pr | 1997 |
Acid-base analysis during experimental anemia in rats.
Topics: Acid-Base Imbalance; Alkalosis, Respiratory; Anemia; Animals; Bicarbonates; Carbon Dioxide; Erythroc | 2000 |
Respiratory alkalosis does not alter NOx concentrations in human plasma and erythrocytes.
Topics: Adult; Alkalosis, Respiratory; Bicarbonates; Carbon Dioxide; Erythrocytes; Female; Humans; Hypervent | 2001 |
Compulsory hyperventilation and hypocapnia of patients with Leigh syndrome associated with SURF1 gene mutations as a cause of low serum bicarbonates.
Topics: Alkalosis, Respiratory; Bicarbonates; Carbon Dioxide; Child; Child, Preschool; Female; Humans; Hydro | 2001 |
Low sodium intake does not impair renal compensation of hypoxia-induced respiratory alkalosis.
Topics: Aldosterone; Alkalosis, Respiratory; Angiotensin II; Animals; Arteries; Atrial Natriuretic Factor; B | 2002 |
Cardiac output response to altered acid-base status during diethyl ether anaesthesia.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Anesthesi | 1975 |
Understanding acid-base disturbances.
Topics: Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Bicarbonate | 1975 |
Importance of changes in plasma HCO-3 on regulation of CSF HCO-3 in respiratory alkalosis.
Topics: Acid-Base Equilibrium; Acidosis; Alkalosis; Alkalosis, Respiratory; Animals; Bicarbonates; Dogs; Hyd | 1976 |
[New blood gas analysis formularies for the differential evaluation of acid-base equilibrium disorders].
Topics: Acid-Base Imbalance; Acidosis, Respiratory; Acute Disease; Adult; Aged; Alkalosis, Respiratory; Bica | 1976 |
Acid-base disorders in pediatrics.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Acidosis, Renal Tubular; Acidosis, Respiratory | 1976 |
Respiratory acidosis and alkalosis.
Topics: Acidosis, Respiratory; Alkalosis, Respiratory; Animals; Bicarbonates; Blood Gas Analysis; Electrolyt | 1977 |
[Blood picture in lactate acidosis. Part 2: acid-base equilibrium and lactate].
Topics: Acid-Base Equilibrium; Acidosis; Alkalosis, Respiratory; Bicarbonates; Carbon Dioxide; Humans; Hydro | 1977 |
Interaction between PCO2 and plasma [HCO-3] in regulation of CSF [HCO-3] in respiratory alkalosis and metabolic acidosis.
Topics: Acidosis; Alkalosis, Respiratory; Animals; Bicarbonates; Carbon Dioxide; Central Nervous System; Cer | 1978 |
Determinants of oxygen uptake during sodium bicarbonate infusion.
Topics: Alkalosis; Alkalosis, Respiratory; Animals; Bicarbonates; Carbon Dioxide; Dogs; Hydrogen-Ion Concent | 1978 |
Normal pregnancy: a model of sustained respiratory alkalosis.
Topics: Acid-Base Equilibrium; Adult; Alkalosis, Respiratory; Bicarbonates; Carbon Dioxide; Female; Humans; | 1979 |
Effect of hypocapnia on intracellular pH during metabolic acidosis.
Topics: Acidosis; Alkalosis, Respiratory; Animals; Bicarbonates; Carbon Dioxide; Chlorides; Hydrogen-Ion Con | 1979 |
Experimental salicylate intoxication in young baboons. A preliminary report.
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Alkalosis, Respiratory; Ammonium Chloride; Animals; As | 1975 |
Evaluation of clinical disorders of acid-base balance.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Animals; | 1975 |
Distribution of H+ and HCO3 minus between CSF and blood during respiratory alkalosis in dogs.
Topics: Acid-Base Equilibrium; Alkalosis, Respiratory; Animals; Bicarbonates; Biological Transport; Blood; C | 1975 |
Recent advances in CSF physiology.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Animals; | 1975 |
The physiological assessment of acid-base balance.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Adult; Aged; Alkalosis; Alkalosis, Respirato | 1975 |
CSF bicarbonate regulation in respiratory acidosis and alkalosis.
Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis, Respiratory; Alkalosis, Respiratory; Ammonia; Ammoni | 1975 |
Clinical use of the anion gap.
Topics: Acid-Base Imbalance; Acidosis; Acidosis, Renal Tubular; Alkalosis; Alkalosis, Respiratory; Aspirin; | 1977 |
Carbon dioxide equilibration in canine lungs during rebreathing and acute alkalosis.
Topics: Acid-Base Equilibrium; Acute Disease; Alkalosis, Respiratory; Animals; Bicarbonates; Carbon Dioxide; | 1979 |
Complex acid-base disorders in subacute necrotizing encephalomyelopathy (Leigh's syndrome).
Topics: Acid-Base Imbalance; Acidosis; Acidosis, Renal Tubular; Alkalosis, Respiratory; Bicarbonates; Brain | 1978 |
Letter: Severe mixed metabolic and respiratory alkalosis in Reye syndrome.
Topics: Alkalosis; Alkalosis, Respiratory; Ammonia; Bicarbonates; Brain Diseases; Carbon Dioxide; Child, Pre | 1976 |
Acute acid-base disorders. 2. Specific disturbances.
Topics: Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Acute Disease; Alkalies; Alkalosis; Alkalosis, | 1976 |
[Acido-basic changes in cerebrospinal fluid during alcoholic predelirium].
Topics: Acid-Base Imbalance; Acidosis, Respiratory; Alcohol Withdrawal Delirium; Alcoholism; Alkalosis, Resp | 1976 |
Renal adaptation to chronic hypocapnia: dietary constraints in achieving H+ retention.
Topics: Alkalosis, Respiratory; Animals; Bicarbonates; Chlorides; Chronic Disease; Diet; Dogs; Female; Hydro | 1975 |
Drug overdose: salicylates.
Topics: Acidosis; Adult; Alkalosis, Respiratory; Bicarbonates; Charcoal; Female; Humans; Poisoning; Salicyla | 1992 |
Plasma potassium and ventilation during incremental exercise in humans: modulation by sodium bicarbonate and substrate availability.
Topics: Acid-Base Equilibrium; Adult; Alkalosis, Respiratory; Bicarbonates; Exercise; Exercise Test; Fatty A | 1992 |
Chronic respiratory alkalosis. The effect of sustained hyperventilation on renal regulation of acid-base equilibrium.
Topics: Acid-Base Equilibrium; Acidosis; Adult; Alkalosis, Respiratory; Ammonium Chloride; Bicarbonates; Car | 1991 |
[Hypo- and hyperventilation: consequences for acid-base balance].
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Alkalosis, Respiratory; Bicarbonates; Humans; Hypercap | 1991 |
Delivery dependence of early proximal bicarbonate reabsorption in the rat in respiratory acidosis and alkalosis.
Topics: Acidosis, Respiratory; Alkalosis, Respiratory; Animals; Bicarbonates; Hypercapnia; Kidney Tubules, P | 1991 |
Role of hormonal factors in plasma K alterations in acute respiratory and metabolic alkalosis in dogs.
Topics: Acid-Base Equilibrium; Acute Disease; Alkalosis; Alkalosis, Respiratory; Animals; Bicarbonates; Dogs | 1990 |
Compensation of respiratory alkalosis induced after acclimation to simulated altitude.
Topics: Acid-Base Equilibrium; Adaptation, Physiological; Alkalosis, Respiratory; Altitude; Animals; Atmosph | 1990 |
Effect of acid-base balance on biliary bicarbonate secretion in the isolated perfused guinea pig liver.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Amiloride | 1990 |
The cellular renal response to respiratory acid-base disorders.
Topics: Alkalosis, Respiratory; Animals; Bicarbonates; Biological Transport; Carbon Dioxide; Endocytosis; Ex | 1985 |
Effects of systemic alkalosis on urinary magnesium excretion in the rat.
Topics: Alkalosis; Alkalosis, Respiratory; Animals; Bicarbonates; Carbon Dioxide; Magnesium; Male; Natriures | 1989 |
Acute electrophysiologic effects of sodium administration in dogs treated with O-desmethyl encainide.
Topics: Alkalosis, Respiratory; Anilides; Animals; Bicarbonates; Dogs; Electroencephalography; Electrophysio | 1989 |
Na-HCO3 cotransport and Na-H antiporter in chronic respiratory acidosis and alkalosis.
Topics: Acidosis, Respiratory; Alkaline Phosphatase; Alkalosis, Respiratory; Animals; Bicarbonates; Carrier | 1989 |
Disturbances in acid-base metabolism. Recognition in the office setting.
Topics: Acid-Base Imbalance; Acidosis; Alkalosis; Alkalosis, Respiratory; Bicarbonates; Diabetic Ketoacidosi | 1988 |
Ketoacid production in acute respiratory and metabolic acidosis and alkalosis in rats.
Topics: Acetoacetates; Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respira | 1989 |
Life-threatening acid-base disorders.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, R | 1985 |
Chronic heat stress and respiratory alkalosis: occurrence and treatment in broiler chicks.
Topics: Alkalosis, Respiratory; Ammonium Chloride; Animals; Bicarbonates; Blood Chemical Analysis; Body Weig | 1985 |
Regulation of net bicarbonate transport in rabbit cortical collecting tubule by peritubular pH, carbon dioxide tension, and bicarbonate concentration.
Topics: Absorption; Acidosis, Respiratory; Alkalosis, Respiratory; Animals; Bicarbonates; Biological Transpo | 1986 |
The lung and fluid-electrolyte and acid-base imbalances.
Topics: Acid-Base Imbalance; Acidosis, Respiratory; Alkalosis, Respiratory; Bicarbonates; Carbon Dioxide; Hu | 1987 |
Suppression of acidification along inner medullary collecting duct.
Topics: Alkalosis, Respiratory; Animals; Bicarbonates; Carbon Dioxide; Glomerular Filtration Rate; Hematocri | 1988 |
Common mistakes in managing metabolic disorders.
Topics: Aged; Alcoholism; Alkalosis, Respiratory; Bicarbonates; Female; Fluid Therapy; Humans; Kidney Failur | 1988 |
A combination of acute metabolic alkalosis superimposed on chronic respiratory alkalosis.
Topics: Alkalosis; Alkalosis, Respiratory; Bicarbonates; Gastrointestinal Hemorrhage; Humans; Kidney; Kidney | 1987 |
Effect of systemic acid-base balance on ileal secretion.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis, Respiratory; Alkalosis, Respiratory; Animals; | 1987 |
Mixed acid-base disorders.
Topics: Acidosis; Acidosis, Respiratory; Adolescent; Aged; Alkalosis; Alkalosis, Respiratory; Bicarbonates; | 1985 |
Influence of chronic respiratory acid-base disorders on acute CO2 titration curve.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis, Respiratory; Alkalosis, Respiratory; Animals; | 1985 |
Response of the renal K+-conserving mechanism to kaliuretic stimuli: evidence for a direct kaliuretic effect by furosemide.
Topics: Absorption; Acidosis; Alkalosis; Alkalosis, Respiratory; Animals; Bicarbonates; Furosemide; Glomerul | 1986 |
[Acid-base equilibrium in anesthesiology and operative intensive care medicine. Physiology, pathophysiology and clinical aspects of alkalosis and mixed disorders].
Topics: Acid-Base Equilibrium; Acidosis; Alkalosis; Alkalosis, Respiratory; Anesthesia, General; Bicarbonate | 1985 |
Glutamate and glutamine in the brain of rats during acute PCO 2 changes.
Topics: Alkalosis, Respiratory; Animals; Bicarbonates; Brain; Carbon Dioxide; Glutamates; Glutamine; Hyperca | 1972 |
Differential effects of furosemide and ethacrynic acid on electrolyte excretion in anesthetized dogs.
Topics: Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Animals; Bicarbonates; Chlorides; Dogs; Et | 1974 |
The "in vivo" and "in vitro" CO2-equilibration curves of blood during acute hypercapnia and hypocapnia. II. Theoretical considerations.
Topics: Acidosis, Respiratory; Alkalosis, Respiratory; Arteries; Bicarbonates; Blood; Carbon Dioxide; Extrac | 1974 |
The "in vivo" and "in vitro" CO2-equilibration curves of blood during acute hypercapnia and hypocapnia. I. Experimental investigations.
Topics: Acidosis, Respiratory; Adult; Alkalosis, Respiratory; Arteries; Bicarbonates; Blood; Carbon Dioxide; | 1974 |
Pulmonary edema: biochemical disorder and management revisited.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Bicarbona | 1972 |
Acid-base balance in cerebrospinal fluid of newborn infants.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Bicarbona | 1972 |
[Acid-base balance in prolonged artificial ventrilation of the lungs in patients with paralysis of the respiratory muscles].
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis, Respiratory; Bicarbonates; Carbon | 1972 |
Acid-base disorders in health and disease.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Bicarbona | 1972 |
CSF acid-base balance and the Wien effect.
Topics: Acid-Base Equilibrium; Acidosis; Alkalosis; Alkalosis, Respiratory; Animals; Bicarbonates; Blood-Bra | 1973 |
Brain organic buffers in respiratory acidosis and alkalosis.
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Ammonia; Animals; B | 1973 |
[Bicarbonate ion in the treatment of simple respiratory alkalosis].
Topics: Acid-Base Equilibrium; Adult; Aged; Alkalosis; Alkalosis, Respiratory; Animals; Bicarbonates; Child; | 1973 |
[Arterial blood gases and asthma].
Topics: Acidosis, Respiratory; Acute Disease; Adult; Airway Obstruction; Alkalosis, Respiratory; Asthma; Bic | 1973 |
Salicylate poisoning.
Topics: Acidosis; Adult; Alkalosis, Respiratory; Anuria; Bicarbonates; Child; Gastric Lavage; Humans; Infusi | 1973 |
Renal function in the dog in acute disturbances of the acid-base balance.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Animals; | 1973 |
The effect of acute hypocapnia upon the energy state of the brain in sustained hyperammonemia.
Topics: Acid-Base Equilibrium; Alkalosis, Respiratory; Ammonia; Animals; Bicarbonates; Blood; Brain; Carbon | 1973 |
[Arterial blood and cerebrospinal fluid acid-base balance in meningococcal meningitis patients with manifestations of cerebral edema].
Topics: Acid-Base Equilibrium; Adolescent; Adult; Alkalosis, Respiratory; Bicarbonates; Blood Gas Analysis; | 1973 |
[Regulation of the acid-base equilibrium of the cerebrospinal fluid in patients with artificial respiration].
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Acute Disease; Adult; Aged; Alkalosis; Alkal | 1973 |
Acid-base balance and arterial and CSF lactate levels following human head injury.
Topics: Acid-Base Equilibrium; Acidosis; Adolescent; Adult; Alkalosis, Respiratory; Bicarbonates; Blood-Brai | 1974 |
Steady state differences in PCO2 [HCO3-] and [H+] between blood and extravascular tissue. Results for lung, CSF and brain.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Animals; | 1972 |
Intracellular buffering in the dog at varying CO 2 tensions.
Topics: Acidosis; Acidosis, Respiratory; Alkalosis, Respiratory; Animals; Bicarbonates; Body Fluids; Buffers | 1972 |
Antepartum and postpartum acid-base changes in maternal blood in normal and complicated pregnancies.
Topics: Acid-Base Equilibrium; Acidosis; Alkalosis, Respiratory; Arteries; Bicarbonates; Capillaries; Carbon | 1972 |
Severe alkalosis in critically ill surgical patients.
Topics: Alkalosis; Alkalosis, Respiratory; Bicarbonates; Extracorporeal Circulation; Female; Humans; Male; P | 1972 |
Mixed metabolic and respiratory acid-base disturbances: diagnosis and treatment.
Topics: Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Bicarbonates; Blood Gas Analysis | 1972 |
[Acid-base equilibrium in collagen diseases].
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Bicarbona | 1972 |
On the interpretation of the -delta (HCO3-) delta-pH ratio in respiratory acid-base disturbances.
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Bicarbonates; Body | 1971 |
The DC potential between CSF and plasma in respiratory acidosis.
Topics: Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Animals; Bicarbonates; Blood Pressure; Car | 1971 |
Compensatory patterns in acid-base disorders.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Bicarbona | 1971 |
The imprecision arising from the application of the Henderson-Hasselbalch relationship to the blood of anesthetized dogs.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis, Respiratory; Anesthesia, General; | 1971 |
The chemical control of ventilation.
Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Adaptation, Physiological; Alkalosis; Alkalo | 1971 |
[Functional and ultrastructural alterations of the brain in hypoxic and normoxic respiratory acisosis].
Topics: Acidosis, Respiratory; Alkalosis, Respiratory; Animals; Bicarbonates; Brain; Carbon Dioxide; Carotid | 1971 |
[Problems in the treatment of acidosis in salicylate poisoning].
Topics: Acidosis; Alkalosis; Alkalosis, Respiratory; Bicarbonates; Diuretics; Humans; Hydrogen-Ion Concentra | 1970 |
[Respiratory disorders in patients with craniocerebral injuries].
Topics: Alkalosis, Respiratory; Bicarbonates; Brain Injuries; Carbon Dioxide; Humans; Hydrogen-Ion Concentra | 1970 |
[The importance of rehydration in asthmatic children].
Topics: Acidosis; Acidosis, Respiratory; Adolescent; Airway Obstruction; Alkalosis; Alkalosis, Respiratory; | 1970 |
Acid-base balance in bacteremic shock.
Topics: Acid-Base Equilibrium; Acidosis; Alkalosis; Alkalosis, Respiratory; Bicarbonates; Blood Pressure; Bu | 1971 |