Page last updated: 2024-10-18

hydrogen carbonate and Albuminuria

hydrogen carbonate has been researched along with Albuminuria in 13 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Albuminuria: The presence of albumin in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
" We conducted a double-blind, placebo-controlled trial in 81 patients with diabetes, hypertension, and albuminuria (urine albumin-to-creatinine ratio > or =300 mg/g) who all received lisinopril (80 mg once daily)."5.14Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy. ( Adams-Huet, B; Mehdi, UF; Raskin, P; Toto, RD; Vega, GL, 2009)
"Sodium bicarbonate (NaHCO3) was administered to 8 of these animals before CA or AA."1.27Effect of urinary alkalinization on renal changes produced by cationic albumin. ( Coimbra, TM; De Carvalho, IF; DeGiacobbi, G; Gouveia, MA; Lachat, JJ, 1984)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's2 (15.38)18.2507
2000's1 (7.69)29.6817
2010's4 (30.77)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Murray, AM1
Slinin, Y1
Tupper, DE1
Pederson, SL1
Davey, C1
Gilbertson, DT1
Drawz, P1
Mello, R1
Hart, A1
Johansen, KL1
Reule, S1
Rossom, R1
Knopman, DS1
Lee, YJ1
Cho, S1
Kim, SR1
Driver, TH1
Shlipak, MG1
Katz, R1
Goldenstein, L1
Sarnak, MJ1
Hoofnagle, AN1
Siscovick, DS1
Kestenbaum, B1
de Boer, IH1
Ix, JH1
Mehdi, UF1
Adams-Huet, B1
Raskin, P1
Vega, GL1
Toto, RD1
He, FJ1
Marciniak, M1
Carney, C1
Markandu, ND1
Anand, V1
Fraser, WD1
Dalton, RN1
Kaski, JC1
MacGregor, GA1
Raphael, KL1
Zhang, Y1
Wei, G1
Greene, T1
Cheung, AK1
Beddhu, S1
RICHARDS, W1
DONNELL, GN1
WILSON, WA1
STOWENS, D1
PERRY, T1
Joles, JA1
Nicaise, E1
Sanders, M1
Schot, A1
Coimbra, TM1
DeGiacobbi, G1
Gouveia, MA1
Lachat, JJ1
De Carvalho, IF1
Kamper, AL1
Strandgaard, S1
Leyssac, PP1
Odum, L1
Hansen-Nord, G1
Nielsen, CA1
Pun, KK1
Ho, PW1
Varghese, Z1
Moorhead, JF1
Bichler, KH1
Porzsolt, F1
Naber, K1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot Study of Sodium Bicarbonate in Generally Healthy People With Low Bicarbonate[NCT02743650]7 participants (Actual)Interventional2016-02-29Terminated (stopped due to Difficulties identifying subjects who were qualified to participate in the study)
Value of Liquid Potassium Magnesium Citrate in Controlling Hypertension[NCT02653560]Phase 430 participants (Actual)Interventional2012-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

24-hour Average Systolic Blood Pressure

Systolic blood pressure was measured through an ambulatory blood pressure monitoring device worn by each participant for 24 hours after completing each treatment phase. This devise measures blood pressure intermittently throughout the day and night and provides the average of all readings. (NCT02653560)
Timeframe: 4 weeks

InterventionmmHg (Mean)
Potassium Magnesium Citrate (KMgCit) Arm127
Potassium Citrate Arm127
Potassium Chloride Arm126
Placebo129

Trials

3 trials available for hydrogen carbonate and Albuminuria

ArticleYear
Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy.
    Journal of the American Society of Nephrology : JASN, 2009, Volume: 20, Issue:12

    Topics: Adult; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitor

2009
Effects of potassium chloride and potassium bicarbonate on endothelial function, cardiovascular risk factors, and bone turnover in mild hypertensives.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:3

    Topics: Adult; Albuminuria; Bicarbonates; Blood Pressure; Bone Remodeling; Brachial Artery; Calcium; Cross-O

2010
Effect of enalapril on the progression of chronic renal failure. A randomized controlled trial.
    American journal of hypertension, 1992, Volume: 5, Issue:7

    Topics: Adolescent; Adult; Aged; Albuminuria; Antihypertensive Agents; Bicarbonates; Blood Pressure; Body We

1992

Other Studies

10 other studies available for hydrogen carbonate and Albuminuria

ArticleYear
Kidney-Metabolic Factors Associated with Cognitive Impairment in Chronic Kidney Disease: A Pilot Study.
    American journal of nephrology, 2022, Volume: 53, Issue:6

    Topics: Aged; Albuminuria; Bicarbonates; Carbon Dioxide; Cognitive Dysfunction; Cross-Sectional Studies; Glo

2022
Association between serum bicarbonate levels and albuminuria in stage 3 and stage 4 chronic kidney disease: a cross-sectional study.
    Clinical nephrology, 2014, Volume: 81, Issue:6

    Topics: Aged; Albuminuria; Bicarbonates; Biomarkers; Chi-Square Distribution; Creatinine; Cross-Sectional St

2014
Low serum bicarbonate and kidney function decline: the Multi-Ethnic Study of Atherosclerosis (MESA).
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 64, Issue:4

    Topics: Acidosis; Aged; Albuminuria; Atherosclerosis; Bicarbonates; Cohort Studies; Creatinine; Cystatin C;

2014
Serum bicarbonate and mortality in adults in NHANES III.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2013, Volume: 28, Issue:5

    Topics: Adult; Aged; Albuminuria; Bicarbonates; Biomarkers; Body Mass Index; Cardiovascular Diseases; Female

2013
THE OCULO-CEREBRO-RENAL SYNDROME OF LOWE.
    American journal of diseases of children (1960), 1965, Volume: 109

    Topics: Albuminuria; Ammonium Chloride; Bicarbonates; Blood; Blood Protein Electrophoresis; Cataract; Child;

1965
Effects of NaHCO3, alpha-, and beta-adrenergic blockade on albuminuria after swimming in splenectomized dogs.
    International journal of sports medicine, 1984, Volume: 5, Issue:6

    Topics: Acidosis; Albuminuria; Animals; Bicarbonates; Blood; Dogs; Hydrogen-Ion Concentration; Metoprolol; M

1984
Effect of urinary alkalinization on renal changes produced by cationic albumin.
    Nephron, 1984, Volume: 38, Issue:4

    Topics: Albumins; Albuminuria; Animals; Bicarbonates; Cations; Female; Hydrogen-Ion Concentration; Kidney Tu

1984
Reversible microproteinuria induced by L-aspartate infusion.
    Nephron, 1990, Volume: 56, Issue:1

    Topics: Adult; Albuminuria; Arginine; Aspartic Acid; beta 2-Microglobulin; Bicarbonates; Female; Glycoprotei

1990
Logistic regression model for the assessment of microalbuminuria and microproteinuria in insulin-dependent diabetic patients at risk.
    Computer methods and programs in biomedicine, 1989, Volume: 29, Issue:3

    Topics: Adult; Aged; Albuminuria; Bicarbonates; Creatinine; Diabetes Mellitus, Type 1; Humans; Middle Aged;

1989
[Proteinuria after physical exercise].
    Deutsche medizinische Wochenschrift (1946), 1972, Aug-25, Volume: 97, Issue:34

    Topics: Acidosis; Adult; Albuminuria; Beta-Globulins; Bicarbonates; Ceruloplasmin; Creatinine; Glycoproteins

1972