hydrogen has been researched along with Subarachnoid Hemorrhage in 14 studies
Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.
Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydrogen gas significantly alleviated brain edema and blood-brain barrier disruption, reduced apoptosis, and improved neurologic function at 24 hrs but not 72 hrs after subarachnoid hemorrhage." | 7.78 | Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats. ( Chen, C; Hu, Q; Suzuki, H; Zhan, Y; Zhang, JH; Zhi, X, 2012) |
| " In contrast, the upregulated level of MDA, caspase-12/3 and brain edema was attenuated and the brain injury was substantially alleviated in the hydrogen treated rabbits, but the improvement of neurology outcome was not obvious." | 7.78 | Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits. ( Ma, CY; Shi, JX; Sun, XJ; You, WC; Zhou, ML; Zhu, L; Zhuang, Z, 2012) |
| "A total of 450 patients with high-grade subarachnoid hemorrhage will be randomized to one of three arms: (i) Mg + H2 group, (ii) Mg group, and (iii) control group." | 6.79 | Effects of intravenous infusion of hydrogen-rich fluid combined with intra-cisternal infusion of magnesium sulfate in severe aneurysmal subarachnoid hemorrhage: study protocol for a randomized controlled trial. ( Arimoto, H; Fujii, K; Mori, K; Nagatani, K; Osada, H; Otani, N; Takeuchi, S; Tomura, S; Wada, K, 2014) |
| "Hydrogen has been reported to alleviate early brain injury (EBI) through oxidative stress injury, reactive oxygen species (ROS), and autophagy." | 5.62 | Hydrogen-rich saline alleviates early brain injury through regulating of ER stress and autophagy after experimental subarachnoid hemorrhage. ( Dai, W; Jiang, B; Li, Y; Mao, D; Wu, A; Wu, H, 2021) |
| "Hydrogen can inhibit neuronal apoptosis and attenuate EBI following SAH." | 5.40 | Neuroprotective effect of hydrogen-rich saline against neurologic damage and apoptosis in early brain injury following subarachnoid hemorrhage: possible role of the Akt/GSK3β signaling pathway. ( Chen, S; Hong, Y; McBride, DW; Shao, A; Sun, X; Wang, J; Wu, H; Wu, Q; Zhang, J, 2014) |
| "Hydrogen gas significantly alleviated brain edema and blood-brain barrier disruption, reduced apoptosis, and improved neurologic function at 24 hrs but not 72 hrs after subarachnoid hemorrhage." | 3.78 | Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats. ( Chen, C; Hu, Q; Suzuki, H; Zhan, Y; Zhang, JH; Zhi, X, 2012) |
| " In contrast, the upregulated level of MDA, caspase-12/3 and brain edema was attenuated and the brain injury was substantially alleviated in the hydrogen treated rabbits, but the improvement of neurology outcome was not obvious." | 3.78 | Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits. ( Ma, CY; Shi, JX; Sun, XJ; You, WC; Zhou, ML; Zhu, L; Zhuang, Z, 2012) |
| "A total of 450 patients with high-grade subarachnoid hemorrhage will be randomized to one of three arms: (i) Mg + H2 group, (ii) Mg group, and (iii) control group." | 2.79 | Effects of intravenous infusion of hydrogen-rich fluid combined with intra-cisternal infusion of magnesium sulfate in severe aneurysmal subarachnoid hemorrhage: study protocol for a randomized controlled trial. ( Arimoto, H; Fujii, K; Mori, K; Nagatani, K; Osada, H; Otani, N; Takeuchi, S; Tomura, S; Wada, K, 2014) |
| "Hydrogen has been reported to alleviate early brain injury (EBI) through oxidative stress injury, reactive oxygen species (ROS), and autophagy." | 1.62 | Hydrogen-rich saline alleviates early brain injury through regulating of ER stress and autophagy after experimental subarachnoid hemorrhage. ( Dai, W; Jiang, B; Li, Y; Mao, D; Wu, A; Wu, H, 2021) |
| "Hydrogen can inhibit neuronal apoptosis and attenuate EBI following SAH." | 1.40 | Neuroprotective effect of hydrogen-rich saline against neurologic damage and apoptosis in early brain injury following subarachnoid hemorrhage: possible role of the Akt/GSK3β signaling pathway. ( Chen, S; Hong, Y; McBride, DW; Shao, A; Sun, X; Wang, J; Wu, H; Wu, Q; Zhang, J, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, B | 1 |
| Li, Y | 1 |
| Dai, W | 1 |
| Wu, A | 1 |
| Wu, H | 3 |
| Mao, D | 1 |
| Kumagai, K | 1 |
| Toyooka, T | 1 |
| Takeuchi, S | 2 |
| Otani, N | 2 |
| Wada, K | 2 |
| Tomiyama, A | 1 |
| Mori, K | 2 |
| Amory, CF | 1 |
| Varelas, PN | 1 |
| Zhuang, Z | 2 |
| Sun, XJ | 2 |
| Zhang, X | 1 |
| Liu, HD | 1 |
| You, WC | 2 |
| Ma, CY | 2 |
| Zhu, L | 2 |
| Zhou, ML | 2 |
| Shi, JX | 2 |
| Hong, Y | 3 |
| Shao, A | 2 |
| Wang, J | 1 |
| Chen, S | 2 |
| McBride, DW | 1 |
| Wu, Q | 2 |
| Sun, X | 3 |
| Zhang, J | 3 |
| Arimoto, H | 1 |
| Fujii, K | 1 |
| Nagatani, K | 1 |
| Tomura, S | 1 |
| Osada, H | 1 |
| Tu, S | 1 |
| Zhao, Q | 1 |
| Sheng, J | 1 |
| Zhan, Y | 1 |
| Chen, C | 1 |
| Suzuki, H | 1 |
| Hu, Q | 1 |
| Zhi, X | 1 |
| Zhang, JH | 1 |
| Hardeland, R | 1 |
| Guo, S | 1 |
| Sun, C | 1 |
| Charbel, FT | 1 |
| Du, X | 1 |
| Hoffman, WE | 1 |
| Ausman, JI | 1 |
| Moon, MS | 1 |
| Kim, I | 1 |
| Ok, IY | 1 |
| Lee, KW | 1 |
| Jorgensen, PB | 1 |
1 trial available for hydrogen and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Effects of intravenous infusion of hydrogen-rich fluid combined with intra-cisternal infusion of magnesium sulfate in severe aneurysmal subarachnoid hemorrhage: study protocol for a randomized controlled trial.
Topics: Adult; Aged; Clinical Protocols; Humans; Hydrogen; Infusions, Intravenous; Infusions, Parenteral; In | 2014 |
13 other studies available for hydrogen and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Hydrogen-rich saline alleviates early brain injury through regulating of ER stress and autophagy after experimental subarachnoid hemorrhage.
Topics: Animals; Apoptosis; Autophagy; Brain; Brain Injuries; Hydrogen; Mice; Mice, Inbred C57BL; Neuroprote | 2021 |
Hydrogen gas inhalation improves delayed brain injury by alleviating early brain injury after experimental subarachnoid hemorrhage.
Topics: Administration, Inhalation; Animals; Blood Pressure; Brain; Brain Edema; Brain Injuries; Cell Death; | 2020 |
Magnesium and Hydrogen in Subarachnoid Hemorrhage: Is Neuroprotection Finally a Reality?
Topics: Humans; Hydrogen; Magnesium; Magnesium Sulfate; Neuroprotection; Subarachnoid Hemorrhage | 2021 |
Nuclear factor-κB/Bcl-XL pathway is involved in the protective effect of hydrogen-rich saline on the brain following experimental subarachnoid hemorrhage in rabbits.
Topics: Animals; Apoptosis; bcl-X Protein; Blotting, Western; Disease Models, Animal; Electrophoretic Mobili | 2013 |
Neuroprotective effect of hydrogen-rich saline against neurologic damage and apoptosis in early brain injury following subarachnoid hemorrhage: possible role of the Akt/GSK3β signaling pathway.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cerebral Cortex; Chromones; Glycogen Synthase Kin | 2014 |
Hydrogen-Rich Saline Attenuated Subarachnoid Hemorrhage-Induced Early Brain Injury in Rats by Suppressing Inflammatory Response: Possible Involvement of NF-κB Pathway and NLRP3 Inflammasome.
Topics: Animals; Antioxidants; Apoptosis; Brain; Brain Edema; Brain Injuries; Cerebral Cortex; Cytokines; Do | 2016 |
Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats.
Topics: Administration, Inhalation; Animals; Antioxidants; Apoptosis; Blood-Brain Barrier; Brain; Brain Chem | 2012 |
Hydrogen therapy: a future option in critical care?
Topics: Animals; Antioxidants; Brain Injuries; Hydrogen; Male; Oxidative Stress; Subarachnoid Hemorrhage | 2012 |
Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits.
Topics: Analysis of Variance; Animals; Brain Edema; Brain Injuries; Caspase 12; Caspase 3; Cell Death; Cereb | 2012 |
Beneficial effect of hydrogen-rich saline on cerebral vasospasm after experimental subarachnoid hemorrhage in rats.
Topics: Animals; Antioxidants; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Enzyme-Linked I | 2012 |
Brain tissue PO(2), PCO(2), and pH during cerebral vasospasm.
Topics: Aged; Brain; Brain Ischemia; Carbon Dioxide; Female; Humans; Hydrogen; Hydrogen-Ion Concentration; I | 2000 |
The response of nerve tissue to chymopapain.
Topics: Animals; Chymopapain; Gangliosides; Hydrogen; Injections, Epidural; Necrosis; Nerve Regeneration; Ne | 1990 |
Brain death. Cerebral appearance of inhaled hydrogen in the diagnosis of cerebral circulatry arrest.
Topics: Adult; Brain Chemistry; Brain Death; Brain Injuries; Brain Neoplasms; Cerebral Angiography; Cerebral | 1974 |